IL89929A0 - Beta-lactam derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Beta-lactam derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL89929A0
IL89929A0 IL89929A IL8992989A IL89929A0 IL 89929 A0 IL89929 A0 IL 89929A0 IL 89929 A IL89929 A IL 89929A IL 8992989 A IL8992989 A IL 8992989A IL 89929 A0 IL89929 A0 IL 89929A0
Authority
IL
Israel
Prior art keywords
preparation
beta
pharmaceutical compositions
compositions containing
lactam derivatives
Prior art date
Application number
IL89929A
Other languages
English (en)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IL89929A0 publication Critical patent/IL89929A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
IL89929A 1988-04-13 1989-04-12 Beta-lactam derivatives,their preparation and pharmaceutical compositions containing them IL89929A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888808701A GB8808701D0 (en) 1988-04-13 1988-04-13 Beta-lactam derivatives

Publications (1)

Publication Number Publication Date
IL89929A0 true IL89929A0 (en) 1989-12-15

Family

ID=10635113

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89929A IL89929A0 (en) 1988-04-13 1989-04-12 Beta-lactam derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US5077286A (de)
EP (1) EP0337704B1 (de)
JP (1) JP2840286B2 (de)
KR (1) KR0138771B1 (de)
CN (1) CN1037151A (de)
AT (1) ATE123778T1 (de)
AU (1) AU615048B2 (de)
CA (1) CA1325077C (de)
DE (1) DE68923033T2 (de)
DK (1) DK175689A (de)
ES (1) ES2075850T3 (de)
FI (1) FI93731C (de)
GB (1) GB8808701D0 (de)
GR (1) GR3017081T3 (de)
HU (1) HU206118B (de)
IE (1) IE67549B1 (de)
IL (1) IL89929A0 (de)
MY (1) MY104428A (de)
NO (1) NO173016C (de)
NZ (1) NZ228681A (de)
SU (2) SU1750430A3 (de)
YU (1) YU47481B (de)
ZA (1) ZA892629B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132301A (en) * 1983-05-02 1992-07-21 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
GB8811388D0 (en) * 1988-05-13 1988-06-15 Erba Carlo Spa 1,1-dioxo-cephem-4-carbothiolic acid derivatives
AU661453B2 (en) * 1989-10-06 1995-07-27 Synphar Laboratories, Inc. Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof
US5264429A (en) * 1989-10-06 1993-11-23 Synphar Laboratories, Inc. 2-spirocyclopropyl cephalosporin sulfone derivatives
GB8928373D0 (en) * 1989-12-15 1990-02-21 Erba Carlo Spa Beta-lactam derivatives
GB9011463D0 (en) * 1990-05-22 1990-07-11 Erba Carlo Spa Process for the preparation of 7 alpha-alkoxycephem derivatives
US5162348A (en) * 1990-05-24 1992-11-10 Imperial Chemical Industries Plc Treatment of cystic fibrosis
DE69129083T2 (de) * 1990-05-24 1998-07-09 Zeneca Ltd Therapeutisches Mittel zur Vorbeugung und Behandlung des Atemnotsyndroms bei Erwachsenen
EP0458537B1 (de) * 1990-05-24 1999-03-31 Zeneca Limited Verwendung einer therapeutischen Zusammensetzung zur Behandlung von Bronchitis
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems
US5446037A (en) * 1991-12-05 1995-08-29 Synphar Laboratories, Inc. 2-[(substituted) methylene]cephalosporin sulfones as antiinflammatory, antidegenerative and antithrombin agents
DE69331089T2 (de) * 1992-02-18 2002-07-18 Otsuka Kagaku K.K., Osaka Beta-Laktam und Cepham Verbindungen und Ihre Herstellung
GB9207715D0 (en) * 1992-04-08 1992-05-27 Erba Carlo Spa 2,2-disubstituted cephem sulphones
WO1993024493A1 (fr) * 1992-05-27 1993-12-09 Teijin Limited Derive de cephalosporine
GB2273097B (en) * 1992-12-04 1996-09-18 Erba Carlo Spa 4-Alkyl and 4-alkenyl delta-3-cephem sulphone human leukocyte elastase inhibitors
AU685433B2 (en) 1993-02-12 1998-01-22 Regents Of The University Of Minnesota Pulmonary administration of sCR1 and other complement inhibitory proteins
GB9304440D0 (en) * 1993-03-04 1993-04-21 Erba Carlo Spa 2-acyloxycephem derivatives
US5439904A (en) * 1993-12-07 1995-08-08 Synphar Laboratories, Inc. 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents
US5629306A (en) 1994-12-09 1997-05-13 Research Corporation Technologies, Inc. 7-alkylidene cephalosporanic acid derivatives and methods of using the same
US5597817A (en) * 1994-12-09 1997-01-28 Southern Methodist University 7-vinylidene cephalosporins and methods of using the same
GB9513818D0 (en) * 1995-07-06 1995-09-06 Pharmacia Spa 7,7-Disubstituted cephem-4-ketones
US5760027A (en) * 1996-12-06 1998-06-02 Research Corporation Technologies, Inc. Use of 7-alkylidene cephalosporins to inhibit elastase activity
US6407091B1 (en) * 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
AU2004268593B2 (en) * 2003-08-25 2012-02-02 Revaax Pharmaceuticals, Llc Oral neurotherapeutic cefazolin compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799922A (en) * 1971-11-17 1974-03-26 Smithkline Corp 4-substituted 3-cephem compounds
IN149747B (de) * 1977-06-07 1982-04-03 Pfizer
NZ190797A (en) * 1978-06-06 1982-08-17 Pfizer Combination of penicillanic 1,1-dioxide and 7-(d-2-(4-ethylpiperazin-2 3-dione-1-carboxamido)-2-(4-hydroxphenyl)acetamido)-3-(1-methyl-5-tetrazolyl)-thiomethyl-3-desacetoxymethylcephalosporanic acid
NZ193020A (en) * 1979-03-05 1982-11-23 Pfizer Preparation of penicillanic acid 1,1-dioxide and intermediates therefor
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4381263A (en) * 1981-03-23 1983-04-26 Pfizer Inc. Process for the preparation of penicillanic acid esters
IN159362B (de) * 1981-03-23 1987-05-09 Pfizer
US4547371A (en) * 1983-04-18 1985-10-15 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
US4637999A (en) * 1983-05-02 1987-01-20 Merck & Co., Inc. Substituted cephalosporins as anti-inflammatory and antidegenerative agents
EP0124081A3 (de) * 1983-05-02 1986-11-26 Merck & Co. Inc. Substituierte Cephalosporinsulfone mit Antientzündungs- und Antidegenerativwirkung, sie enthaltende Zusammensetzungen und Verfahren zur Herstellung
US4468351A (en) * 1983-06-06 1984-08-28 Pfizer Inc. Process for debromination of dibromopenicillanic acid and derivatives
JPS62284386A (ja) * 1986-06-03 1987-12-10 日立電子エンジニアリング株式会社 プロ−ビング方式
EP0267723B1 (de) * 1986-11-12 1996-02-07 Merck & Co. Inc. Substituierte Cephalosporinsulfone als anti-entzündliche und anti-degenerative Mittel

Also Published As

Publication number Publication date
GB8808701D0 (en) 1988-05-18
SU1750430A3 (ru) 1992-07-23
JP2840286B2 (ja) 1998-12-24
IE891132L (en) 1989-10-13
YU74489A (en) 1991-02-28
HUT50348A (en) 1990-01-29
DK175689A (da) 1989-10-14
DE68923033T2 (de) 1995-10-26
NZ228681A (en) 1991-07-26
NO173016C (no) 1993-10-13
AU3276289A (en) 1989-10-19
EP0337704A3 (de) 1991-09-25
HU206118B (en) 1992-08-28
CA1325077C (en) 1993-12-07
FI93731B (fi) 1995-02-15
KR0138771B1 (ko) 1998-05-15
EP0337704B1 (de) 1995-06-14
DE68923033D1 (de) 1995-07-20
MY104428A (en) 1994-03-31
FI891700A0 (fi) 1989-04-11
NO891516L (no) 1989-10-16
YU47481B (sh) 1995-10-03
AU615048B2 (en) 1991-09-19
FI93731C (fi) 1995-05-26
US5077286A (en) 1991-12-31
KR890016048A (ko) 1989-11-28
IE67549B1 (en) 1996-04-17
EP0337704A2 (de) 1989-10-18
ZA892629B (en) 1989-12-27
FI891700A (fi) 1989-10-14
ES2075850T3 (es) 1995-10-16
GR3017081T3 (en) 1995-11-30
ATE123778T1 (de) 1995-06-15
DK175689D0 (da) 1989-04-12
NO891516D0 (no) 1989-04-12
SU1766261A3 (ru) 1992-09-30
CN1037151A (zh) 1989-11-15
JPH0228183A (ja) 1990-01-30
NO173016B (no) 1993-07-05

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)
RH Patent void