IL89481A - Hypoglycemic and hypocholesterolemic thiazolidine 2,4-dione derivatives and compositions containing them - Google Patents

Hypoglycemic and hypocholesterolemic thiazolidine 2,4-dione derivatives and compositions containing them

Info

Publication number
IL89481A
IL89481A IL89481A IL8948189A IL89481A IL 89481 A IL89481 A IL 89481A IL 89481 A IL89481 A IL 89481A IL 8948189 A IL8948189 A IL 8948189A IL 89481 A IL89481 A IL 89481A
Authority
IL
Israel
Prior art keywords
hypocholesterolemic
thiazolidine
hypoglycemic
compositions containing
dione derivatives
Prior art date
Application number
IL89481A
Other languages
English (en)
Other versions
IL89481A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL89481A0 publication Critical patent/IL89481A0/xx
Publication of IL89481A publication Critical patent/IL89481A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cleaning Or Clearing Of The Surface Of Open Water (AREA)
  • Treatment Of Fiber Materials (AREA)
IL89481A 1988-03-08 1989-03-03 Hypoglycemic and hypocholesterolemic thiazolidine 2,4-dione derivatives and compositions containing them IL89481A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1988/000745 WO1989008652A1 (en) 1988-03-08 1988-03-08 Thiazolidinedione derivatives as hypoglycemic agents

Publications (2)

Publication Number Publication Date
IL89481A0 IL89481A0 (en) 1989-09-10
IL89481A true IL89481A (en) 1993-02-21

Family

ID=22208591

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89481A IL89481A (en) 1988-03-08 1989-03-03 Hypoglycemic and hypocholesterolemic thiazolidine 2,4-dione derivatives and compositions containing them

Country Status (17)

Country Link
EP (1) EP0389699B1 (zh)
JP (1) JPH01299289A (zh)
KR (1) KR910000734B1 (zh)
CN (1) CN1026234C (zh)
AU (1) AU594899B2 (zh)
CA (1) CA1328265C (zh)
DK (1) DK108789A (zh)
ES (3) ES2052906T3 (zh)
FI (1) FI92696C (zh)
HU (1) HU217432B (zh)
IL (1) IL89481A (zh)
MY (1) MY103837A (zh)
NO (1) NO178068C (zh)
NZ (1) NZ228247A (zh)
PT (1) PT89922B (zh)
WO (1) WO1989008652A1 (zh)
ZA (1) ZA891681B (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
GB8919417D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
DE69106714T2 (de) * 1990-08-23 1995-05-11 Pfizer Hypoglykämische hydroxyharnstoffderivate.
FR2696743B1 (fr) * 1992-10-12 1994-12-23 Adir Nouveaux composés de thiazolidine dione, leur procédé de préparation et les compositions pharmaceutiques les contenant.
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
JPH08157473A (ja) * 1994-10-06 1996-06-18 Nissan Chem Ind Ltd ピラゾール系チアゾリジン類
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents
JP3906935B2 (ja) * 1995-12-18 2007-04-18 杏林製薬株式会社 Ｎ−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法
WO1997032863A1 (fr) * 1996-03-08 1997-09-12 Torii Pharmaceutical Co., Ltd. Derives de thiazolidine-2,4-dione
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
WO2000008018A1 (fr) * 1998-08-07 2000-02-17 Takeda Chemical Industries, Ltd. Derives de benzothiepine, leur procede de preparation et leurs utilisations
CA2380206A1 (en) 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Pharmaceutical compositions exhibiting thrombopoietin receptor agonism
JP4316787B2 (ja) * 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、
DE10029077A1 (de) 2000-06-13 2001-12-20 Bayer Ag Thiazolylsubstituierte Heterocyclen
US20040063764A1 (en) * 2001-01-26 2004-04-01 Hiroshi Takemoto Halogen compounds having thrombopoietin receptor agonism
EP1357116A4 (en) * 2001-02-02 2005-06-01 Yamanouchi Pharma Co Ltd 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF
DE10331675A1 (de) 2003-07-14 2005-02-10 Bayer Cropscience Ag Hetarylsubstituierte Pyrazolidindion-Derivate
US8492428B2 (en) 2005-09-20 2013-07-23 Mayo Foundation For Medical Education And Research Small-molecule botulinum toxin inhibitors
GB2465890A (en) * 2008-12-05 2010-06-09 Scynexis Inc 2-Arylazole derivatives as antiprotozoal agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
HU210339B (en) * 1985-05-21 1995-03-28 Pfizer Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物

Also Published As

Publication number Publication date
CA1328265C (en) 1994-04-05
PT89922B (pt) 1995-03-01
AU3107789A (en) 1989-09-14
IL89481A0 (en) 1989-09-10
ES2052907T3 (es) 1994-07-16
JPH0585551B2 (zh) 1993-12-07
FI92696B (fi) 1994-09-15
HUT54680A (en) 1991-03-28
FI92696C (fi) 1994-12-27
MY103837A (en) 1993-09-30
NZ228247A (en) 1990-05-28
NO178068B (no) 1995-10-09
EP0389699A1 (en) 1990-10-03
FI904413A0 (fi) 1990-09-07
NO903863D0 (no) 1990-09-05
DK108789A (da) 1989-09-09
HU882181D0 (en) 1991-01-28
ZA891681B (en) 1990-10-31
DK108789D0 (da) 1989-03-07
EP0389699B1 (en) 1994-05-11
PT89922A (pt) 1989-11-10
ES2052906T3 (es) 1994-07-16
JPH01299289A (ja) 1989-12-04
WO1989008652A1 (en) 1989-09-21
KR890014534A (ko) 1989-10-24
CN1036572A (zh) 1989-10-25
KR910000734B1 (ko) 1991-02-06
NO178068C (no) 1996-01-17
ES2052910T3 (es) 1994-07-16
NO903863L (no) 1990-09-05
AU594899B2 (en) 1990-03-15
HU217432B (hu) 2000-01-28
CN1026234C (zh) 1994-10-19

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees