IL88742A - Hiv inhibiting compositions containing polyhydroxy derivatives of pyrrolidine and certain novel derivatives thereof - Google Patents
Hiv inhibiting compositions containing polyhydroxy derivatives of pyrrolidine and certain novel derivatives thereofInfo
- Publication number
- IL88742A IL88742A IL88742A IL8874288A IL88742A IL 88742 A IL88742 A IL 88742A IL 88742 A IL88742 A IL 88742A IL 8874288 A IL8874288 A IL 8874288A IL 88742 A IL88742 A IL 88742A
- Authority
- IL
- Israel
- Prior art keywords
- dideoxy
- imino
- derivatives
- methyl
- pyrrolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13621987A | 1987-12-21 | 1987-12-21 | |
| US07/249,144 US4999360A (en) | 1987-12-21 | 1988-09-26 | Method of inhibiting virus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL88742A0 IL88742A0 (en) | 1989-07-31 |
| IL88742A true IL88742A (en) | 1993-08-18 |
Family
ID=26834131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL88742A IL88742A (en) | 1987-12-21 | 1988-12-20 | Hiv inhibiting compositions containing polyhydroxy derivatives of pyrrolidine and certain novel derivatives thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4999360A (xx) |
| EP (1) | EP0322395B1 (xx) |
| JP (1) | JP2538014B2 (xx) |
| KR (1) | KR910009994B1 (xx) |
| AT (1) | ATE87206T1 (xx) |
| AU (1) | AU607834B2 (xx) |
| CA (1) | CA1316929C (xx) |
| DE (1) | DE3879653T2 (xx) |
| DK (1) | DK175113B1 (xx) |
| FI (1) | FI93210C (xx) |
| IE (1) | IE63095B1 (xx) |
| IL (1) | IL88742A (xx) |
| NO (1) | NO172340C (xx) |
| NZ (1) | NZ227410A (xx) |
| OA (1) | OA08937A (xx) |
| PT (1) | PT89267B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68925940T2 (de) * | 1988-11-03 | 1996-10-24 | Searle & Co | Dideoxy-L-arabinitol Derivate als Antivirus-Verbindungen |
| US4894388A (en) * | 1988-12-22 | 1990-01-16 | Monsanto Company | Glycosidase inhibitors and use thereof |
| US5100797A (en) * | 1989-06-27 | 1992-03-31 | Monsanto Company | Fucosidase inhibitors |
| US5043273A (en) * | 1989-08-17 | 1991-08-27 | Monsanto Company | Phosphorylated glycosidase inhibitor prodrugs |
| IT1239950B (it) * | 1990-03-28 | 1993-11-27 | Zambon Spa | Processo per la preparazione di composti con attivita' analgesica centrale |
| US5536732A (en) * | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
| US5252587A (en) * | 1990-04-27 | 1993-10-12 | Merrell Dow Pharmaceuticals, Inc. | N-derivatives of 1-deoxy nojirimycin |
| US5290948A (en) * | 1990-09-17 | 1994-03-01 | Mcneilab, Inc. | Process for producing polyhydroxylated piperidines and pyrrolidines and compounds thereof |
| GB9026271D0 (en) * | 1990-12-03 | 1991-01-16 | Alphey Thomas J W | Control of parasitic nematodes(a) |
| US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
| US5451679A (en) * | 1994-03-08 | 1995-09-19 | G. D. Searle & Co. | 2-chloro and 2-bromo derivatives of 1,5-iminosugars |
| CZ120398A3 (cs) * | 1995-09-08 | 1998-12-16 | Novo Nordisk A/S | Použití 2-alkylpyrrolidinových derivátů pro přípravu léčiva pro léčbu diabetu, 2-alkylpyrrolidiné deriváty |
| CN102399228B (zh) * | 2010-09-08 | 2013-10-16 | 中国科学院成都生物研究所 | N-烷基多羟基哌啶衍生物的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
| US4065562A (en) * | 1975-12-29 | 1977-12-27 | Nippon Shinyaku Co., Ltd. | Method and composition for reducing blood glucose levels |
| DE3038901A1 (de) * | 1980-10-15 | 1982-05-06 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins |
| DE3507019A1 (de) * | 1985-02-28 | 1986-08-28 | Bayer Ag, 5090 Leverkusen | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung |
| EP0252962B1 (en) * | 1985-12-23 | 1995-08-23 | Fred Hutchinson Cancer Research Center | Regulating retroviral replication, infection, and pathogenesis |
-
1988
- 1988-09-26 US US07/249,144 patent/US4999360A/en not_active Expired - Lifetime
- 1988-12-20 KR KR1019880017028A patent/KR910009994B1/ko not_active IP Right Cessation
- 1988-12-20 IE IE379488A patent/IE63095B1/en not_active IP Right Cessation
- 1988-12-20 OA OA59494A patent/OA08937A/xx unknown
- 1988-12-20 AU AU27068/88A patent/AU607834B2/en not_active Ceased
- 1988-12-20 DK DK198807081A patent/DK175113B1/da not_active IP Right Cessation
- 1988-12-20 JP JP63321868A patent/JP2538014B2/ja not_active Expired - Fee Related
- 1988-12-20 FI FI885880A patent/FI93210C/fi not_active IP Right Cessation
- 1988-12-20 PT PT89267A patent/PT89267B/pt active IP Right Revival
- 1988-12-20 CA CA000586466A patent/CA1316929C/en not_active Expired - Fee Related
- 1988-12-20 EP EP88870192A patent/EP0322395B1/en not_active Expired - Lifetime
- 1988-12-20 IL IL88742A patent/IL88742A/xx not_active IP Right Cessation
- 1988-12-20 AT AT88870192T patent/ATE87206T1/de not_active IP Right Cessation
- 1988-12-20 DE DE88870192T patent/DE3879653T2/de not_active Expired - Fee Related
- 1988-12-20 NZ NZ227410A patent/NZ227410A/en unknown
- 1988-12-20 NO NO885655A patent/NO172340C/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO885655L (no) | 1989-06-22 |
| FI885880A0 (fi) | 1988-12-20 |
| DK708188D0 (da) | 1988-12-20 |
| FI93210C (fi) | 1995-03-10 |
| CA1316929C (en) | 1993-04-27 |
| FI93210B (fi) | 1994-11-30 |
| KR910009994B1 (ko) | 1991-12-10 |
| IL88742A0 (en) | 1989-07-31 |
| JP2538014B2 (ja) | 1996-09-25 |
| IE883794L (en) | 1989-06-21 |
| JPH01230517A (ja) | 1989-09-14 |
| EP0322395B1 (en) | 1993-03-24 |
| FI885880A (fi) | 1989-06-22 |
| NO172340C (no) | 1993-07-07 |
| NZ227410A (en) | 1991-06-25 |
| DE3879653T2 (de) | 1993-10-14 |
| OA08937A (fr) | 1989-10-31 |
| IE63095B1 (en) | 1995-03-22 |
| PT89267A (pt) | 1989-12-29 |
| PT89267B (pt) | 1993-12-31 |
| AU2706888A (en) | 1989-06-22 |
| KR890009389A (ko) | 1989-08-01 |
| DE3879653D1 (de) | 1993-04-29 |
| US4999360A (en) | 1991-03-12 |
| AU607834B2 (en) | 1991-03-14 |
| EP0322395A1 (en) | 1989-06-28 |
| DK708188A (da) | 1989-06-22 |
| DK175113B1 (da) | 2004-06-07 |
| NO172340B (no) | 1993-03-29 |
| NO885655D0 (no) | 1988-12-20 |
| ATE87206T1 (de) | 1993-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL111843A (en) | Crystalline 3,4,4-trisubstituted piperidinyl-N-(3-phenylprop-2-YL) carboxylic acid derivatives pharmaceutical compositions containing them and processes for their preparation | |
| HUT46708A (en) | Process for producing heterocyclic ketones and pharmaceutical compositions containing them as active components | |
| HUT58313A (en) | Process for producing pyrrolidine derivatives and pharmaceutical compositions containing them | |
| ZA932168B (en) | Naphthylalkylamines, process for preparing them and pharmaceutical compositions containing them | |
| IL88742A (en) | Hiv inhibiting compositions containing polyhydroxy derivatives of pyrrolidine and certain novel derivatives thereof | |
| IL86381A0 (en) | Oxetanocins and pharmaceutical compositions containing the same | |
| DK0587088T3 (da) | Substituerede cyclohexan-derivater, fremgangsmåde til deres fremstilling og anvendelsen af forbindelserne til behandling af sygdomme | |
| DE68927160D1 (de) | Verwendung von N-Butyl-Deoxynojirimycin zur Behandlung von Herpes | |
| IT1228288B (it) | Composti ad attivita' antiserotoninica | |
| ZA887399B (en) | 4-aminopyridine derivatives | |
| HU9802143D0 (en) | New heterocyclic compounds of 5 members in the ring, process for producing them and pharmaceutical compositions containing them | |
| MX9700807A (es) | Derivados de 3-azabiciclo (3.2.0)heptano n-sustituidos utiles como neurolepticos. | |
| HUT46664A (en) | Process for producing new dihydropyridineamide derivatives and pharmaceutical compositions comprising these compounds | |
| ES2019840A6 (es) | Procedimiento para preparar nuevos derivados de tieno-triazolo-diazepina. | |
| IL88740A0 (en) | Compositions for the inhibition of viruses | |
| ES2065192T3 (es) | Nuevos nicotinatos de diacil-glicerol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| SG48784A1 (en) | Use of tetrahydropyridine derivatives for the preparation of cardioprotective medicaments | |
| HUT44500A (en) | Process for producing methionin-substituted new 1,4-dihydro-pyridine derivatives and pharmaceutical compositions containing them | |
| AU657423B2 (en) | Novel piperidine derivatives and process for preparation thereof | |
| GR3002168T3 (en) | Cis & trans stilbenes and their composition for the treatment of hypertension | |
| HUT58742A (en) | Process for producing alpha-adrenerg-receptor antagonistic thieno-benzazepines and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |