DE3879653D1 - Virusinhibierende heterocyclische verbindungen. - Google Patents
Virusinhibierende heterocyclische verbindungen.Info
- Publication number
- DE3879653D1 DE3879653D1 DE8888870192T DE3879653T DE3879653D1 DE 3879653 D1 DE3879653 D1 DE 3879653D1 DE 8888870192 T DE8888870192 T DE 8888870192T DE 3879653 T DE3879653 T DE 3879653T DE 3879653 D1 DE3879653 D1 DE 3879653D1
- Authority
- DE
- Germany
- Prior art keywords
- dideoxy
- imino
- methyl
- ribitol
- heterocyclic compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13621987A | 1987-12-21 | 1987-12-21 | |
US07/249,144 US4999360A (en) | 1987-12-21 | 1988-09-26 | Method of inhibiting virus |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3879653D1 true DE3879653D1 (de) | 1993-04-29 |
DE3879653T2 DE3879653T2 (de) | 1993-10-14 |
Family
ID=26834131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE88870192T Expired - Fee Related DE3879653T2 (de) | 1987-12-21 | 1988-12-20 | Virusinhibierende heterocyclische Verbindungen. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4999360A (de) |
EP (1) | EP0322395B1 (de) |
JP (1) | JP2538014B2 (de) |
KR (1) | KR910009994B1 (de) |
AT (1) | ATE87206T1 (de) |
AU (1) | AU607834B2 (de) |
CA (1) | CA1316929C (de) |
DE (1) | DE3879653T2 (de) |
DK (1) | DK175113B1 (de) |
FI (1) | FI93210C (de) |
IE (1) | IE63095B1 (de) |
IL (1) | IL88742A (de) |
NO (1) | NO172340C (de) |
NZ (1) | NZ227410A (de) |
OA (1) | OA08937A (de) |
PT (1) | PT89267B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2086323T3 (es) * | 1988-11-03 | 1996-07-01 | Searle & Co | Derivados del didesoxi-arabinitol como compuestos antiviricos. |
US4894388A (en) * | 1988-12-22 | 1990-01-16 | Monsanto Company | Glycosidase inhibitors and use thereof |
US5100797A (en) * | 1989-06-27 | 1992-03-31 | Monsanto Company | Fucosidase inhibitors |
US5043273A (en) * | 1989-08-17 | 1991-08-27 | Monsanto Company | Phosphorylated glycosidase inhibitor prodrugs |
IT1239950B (it) * | 1990-03-28 | 1993-11-27 | Zambon Spa | Processo per la preparazione di composti con attivita' analgesica centrale |
US5536732A (en) * | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
US5252587A (en) * | 1990-04-27 | 1993-10-12 | Merrell Dow Pharmaceuticals, Inc. | N-derivatives of 1-deoxy nojirimycin |
US5290948A (en) * | 1990-09-17 | 1994-03-01 | Mcneilab, Inc. | Process for producing polyhydroxylated piperidines and pyrrolidines and compounds thereof |
GB9026271D0 (en) * | 1990-12-03 | 1991-01-16 | Alphey Thomas J W | Control of parasitic nematodes(a) |
US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
US5451679A (en) * | 1994-03-08 | 1995-09-19 | G. D. Searle & Co. | 2-chloro and 2-bromo derivatives of 1,5-iminosugars |
HUP9901132A2 (hu) * | 1995-09-08 | 1999-07-28 | Novo Nordisk A/S | 2-Alkilpirrolidinek |
CN102399228B (zh) * | 2010-09-08 | 2013-10-16 | 中国科学院成都生物研究所 | N-烷基多羟基哌啶衍生物的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
US4065562A (en) * | 1975-12-29 | 1977-12-27 | Nippon Shinyaku Co., Ltd. | Method and composition for reducing blood glucose levels |
DE3038901A1 (de) * | 1980-10-15 | 1982-05-06 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins |
DE3507019A1 (de) * | 1985-02-28 | 1986-08-28 | Bayer Ag, 5090 Leverkusen | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung |
WO1987003903A1 (en) * | 1985-12-23 | 1987-07-02 | Fred Hutchinson Cancer Research Center | Regulating retroviral replication, infection, and pathogenesis |
-
1988
- 1988-09-26 US US07/249,144 patent/US4999360A/en not_active Expired - Lifetime
- 1988-12-20 EP EP88870192A patent/EP0322395B1/de not_active Expired - Lifetime
- 1988-12-20 AU AU27068/88A patent/AU607834B2/en not_active Ceased
- 1988-12-20 IE IE379488A patent/IE63095B1/en not_active IP Right Cessation
- 1988-12-20 JP JP63321868A patent/JP2538014B2/ja not_active Expired - Fee Related
- 1988-12-20 FI FI885880A patent/FI93210C/fi not_active IP Right Cessation
- 1988-12-20 IL IL88742A patent/IL88742A/xx not_active IP Right Cessation
- 1988-12-20 NZ NZ227410A patent/NZ227410A/en unknown
- 1988-12-20 CA CA000586466A patent/CA1316929C/en not_active Expired - Fee Related
- 1988-12-20 PT PT89267A patent/PT89267B/pt active IP Right Revival
- 1988-12-20 AT AT88870192T patent/ATE87206T1/de not_active IP Right Cessation
- 1988-12-20 DE DE88870192T patent/DE3879653T2/de not_active Expired - Fee Related
- 1988-12-20 KR KR1019880017028A patent/KR910009994B1/ko not_active IP Right Cessation
- 1988-12-20 DK DK198807081A patent/DK175113B1/da not_active IP Right Cessation
- 1988-12-20 NO NO885655A patent/NO172340C/no not_active IP Right Cessation
- 1988-12-20 OA OA59494A patent/OA08937A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE3879653T2 (de) | 1993-10-14 |
EP0322395A1 (de) | 1989-06-28 |
IE63095B1 (en) | 1995-03-22 |
NO172340C (no) | 1993-07-07 |
NO885655D0 (no) | 1988-12-20 |
CA1316929C (en) | 1993-04-27 |
US4999360A (en) | 1991-03-12 |
ATE87206T1 (de) | 1993-04-15 |
AU607834B2 (en) | 1991-03-14 |
KR910009994B1 (ko) | 1991-12-10 |
NO172340B (no) | 1993-03-29 |
DK175113B1 (da) | 2004-06-07 |
EP0322395B1 (de) | 1993-03-24 |
PT89267A (pt) | 1989-12-29 |
JP2538014B2 (ja) | 1996-09-25 |
IL88742A0 (en) | 1989-07-31 |
AU2706888A (en) | 1989-06-22 |
FI93210C (fi) | 1995-03-10 |
FI93210B (fi) | 1994-11-30 |
KR890009389A (ko) | 1989-08-01 |
PT89267B (pt) | 1993-12-31 |
DK708188D0 (da) | 1988-12-20 |
DK708188A (da) | 1989-06-22 |
JPH01230517A (ja) | 1989-09-14 |
FI885880A (fi) | 1989-06-22 |
NO885655L (no) | 1989-06-22 |
FI885880A0 (fi) | 1988-12-20 |
NZ227410A (en) | 1991-06-25 |
OA08937A (fr) | 1989-10-31 |
IE883794L (en) | 1989-06-21 |
IL88742A (en) | 1993-08-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |