IL88145A0 - Monoclonal antibodies against human interleukin-4 and hybridomas producing the same - Google Patents

Monoclonal antibodies against human interleukin-4 and hybridomas producing the same

Info

Publication number
IL88145A0
IL88145A0 IL88145A IL8814588A IL88145A0 IL 88145 A0 IL88145 A0 IL 88145A0 IL 88145 A IL88145 A IL 88145A IL 8814588 A IL8814588 A IL 8814588A IL 88145 A0 IL88145 A0 IL 88145A0
Authority
IL
Israel
Prior art keywords
same
monoclonal antibodies
antibodies against
against human
human interleukin
Prior art date
Application number
IL88145A
Other languages
English (en)
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Publication of IL88145A0 publication Critical patent/IL88145A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/247—IL-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
IL88145A 1987-10-26 1988-10-25 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same IL88145A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/113,623 US5041381A (en) 1986-07-03 1987-10-26 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same

Publications (1)

Publication Number Publication Date
IL88145A0 true IL88145A0 (en) 1989-06-30

Family

ID=22350540

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88145A IL88145A0 (en) 1987-10-26 1988-10-25 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same

Country Status (18)

Country Link
US (1) US5041381A (ja)
EP (2) EP0314402A3 (ja)
JP (1) JPH0698020B2 (ja)
KR (1) KR930008112B1 (ja)
CN (2) CN1032816A (ja)
AU (1) AU611750B2 (ja)
CA (1) CA1335653C (ja)
DE (1) DE3886760T2 (ja)
DK (1) DK169627B1 (ja)
ES (1) ES2061736T3 (ja)
HK (1) HK105996A (ja)
IE (1) IE62491B1 (ja)
IL (1) IL88145A0 (ja)
MY (1) MY108526A (ja)
NZ (1) NZ226692A (ja)
PT (1) PT88847B (ja)
WO (1) WO1989003846A2 (ja)
ZA (1) ZA887987B (ja)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700915A (en) * 1985-11-19 1997-12-23 Schering Corporations Human interleukin immunopurification processes
ES2058490T3 (es) * 1988-02-02 1994-11-01 Schering Biotech Corp Metodo de reducir respuestas de inmunoglobulina e.
JPH05503098A (ja) * 1989-12-15 1993-05-27 カイロン　コーポレイション セプシスの処理のためのサイトカイン抗体
GB8928501D0 (en) * 1989-12-18 1990-02-21 Unilever Plc Reagents
IL96714A0 (en) * 1989-12-20 1991-09-16 Schering Corp Antibody antagonists of human interleukin-4
US5132109A (en) * 1990-10-05 1992-07-21 Ludwig Institute For Cancer Research Method for inhibiting production of ige and method for enhancing production of igg using interleukin 9 and inhibitors thereof
DE4137333A1 (de) * 1991-11-13 1993-05-19 W Prof Dr Sebald Therapeutische mittel, die antagonisten oder partielle agonisten des humanen interleukin 4 sind oder diese enthalten, hil-4-mutantenproteine sowie vefahren zu deren herstellung
US5863537A (en) * 1992-02-19 1999-01-26 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US5714146A (en) * 1992-08-26 1998-02-03 Board Of Regents Of The University Of Washington IL-4 bone therapy
US5928904A (en) * 1993-09-07 1999-07-27 Smithkline Beecham Corporation DNA encoding recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US5914110A (en) * 1993-09-07 1999-06-22 Smithkline Beecham Corporation Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US20020193575A1 (en) * 1993-09-07 2002-12-19 Smithkline Beecham P.L.C. Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
NZ274338A (en) * 1993-09-07 1998-02-26 Smithkline Beecham Corp Chimeric and humanised il-4 monoclonal antibodies and their use
US5959085A (en) * 1993-11-23 1999-09-28 Schering Corporation Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
EP0659766A1 (en) * 1993-11-23 1995-06-28 Schering-Plough Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
AU1744495A (en) * 1994-02-15 1995-08-29 T Cell Diagnostics, Inc. Immunoassay kit comprising universal reagents
US5597710A (en) * 1994-03-10 1997-01-28 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US5705154A (en) * 1995-03-08 1998-01-06 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
AUPN481295A0 (en) * 1995-08-16 1995-09-07 Medvet Science Pty. Ltd. Agonists of haemopoietic growth factors
US20020090682A1 (en) * 1995-10-23 2002-07-11 Tracy Willson Novel haemopoietin receptor and genetic sequences encoding same
DE16192152T1 (de) 2000-05-26 2020-08-06 Immunex Corporation Verwendung von interleukin-4 rezeptor (il-4r) antikörpern und zusammensetzungen davon
GB0210535D0 (en) * 2002-05-08 2002-06-19 Novartis Ag Organic compounds
JP2004045384A (ja) * 2002-05-22 2004-02-12 Matsushita Electric Ind Co Ltd 免疫学的測定方法、免疫学的測定装置、生体成分測定用トイレ、抗アルブミンモノクローナル抗体、それを産生する細胞株、およびアルブミン検出キット
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
AR050044A1 (es) * 2004-08-03 2006-09-20 Novartis Ag Anticuerpo especifico de il-4
US7608693B2 (en) * 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
GB0807214D0 (en) * 2008-04-21 2008-05-28 Belfast Health And Social Care Biomarkers
GB201210587D0 (en) * 2012-06-14 2012-08-01 Belfast Health And Social Care Trust Predictive biomarker
GB201210571D0 (en) * 2012-06-14 2012-08-01 Belfast Health And Social Care Trust Predictive biomarker
CN103421747B (zh) * 2013-09-09 2015-01-07 扬州大学 分泌牛il-4单克隆抗体的杂交瘤细胞株、其单克隆抗体及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255329A (en) 1973-10-02 1981-03-10 Syva Company Double receptor fluorescent immunoassay
US4342832A (en) 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US4431739A (en) * 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein
US4423147A (en) 1980-04-11 1983-12-27 Secher David S Monoclonal antibody to interferon-α
ATE5541T1 (de) 1980-06-20 1983-12-15 Battelle Memorial Institute Verfahren zur delignifizierung von holz und anderen lignocellulosematerialien.
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4355023A (en) 1980-09-30 1982-10-19 The Massachusetts General Hospital Antibody fragment compositions and process
US4599308A (en) 1981-10-06 1986-07-08 Hamer Dean H Protein from SV40 recombinants
US4470925A (en) 1982-05-05 1984-09-11 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
US4474493A (en) 1982-09-09 1984-10-02 Modular Systems, Inc. Dowel fastener and joints including same
EP0189405B1 (en) 1983-09-15 1989-02-22 University Of Bath Disinfection of contact lenses
US4731237A (en) 1983-11-07 1988-03-15 The Wistar Institute Immune response to virus induced by anti-idiotype antibodies
CA1255586A (en) 1984-07-24 1989-06-13 Hendrik M. Geysen Method of determining mimotopes
US4562003A (en) 1984-10-26 1985-12-31 California Biotechnology, Inc. Monoclonal antibodies against alveolar surfactant protein
EP0190711B1 (en) 1985-02-07 1989-04-26 Kowa Company, Ltd. Monoclonal antibodies to tissue plasminogen activator derived from human normal cells
WO1986006487A1 (en) 1985-04-22 1986-11-06 Commonwealth Serum Laboratories Commission Method for determining mimotopes
PT83761B (pt) * 1985-11-19 1989-06-30 Schering Biotech Corp Metodo para a producao de interleuquina-4 de mamifero

Also Published As

Publication number Publication date
DE3886760T2 (de) 1994-09-08
EP0375743A1 (en) 1990-07-04
EP0314402A3 (en) 1989-06-07
JPH03503118A (ja) 1991-07-18
IE62491B1 (en) 1995-02-08
MY108526A (en) 1996-10-31
CN1032816A (zh) 1989-05-10
AU611750B2 (en) 1991-06-20
KR930008112B1 (ko) 1993-08-26
CA1335653C (en) 1995-05-23
DK101890D0 (da) 1990-04-25
DK101890A (da) 1990-04-25
ZA887987B (en) 1990-06-27
CN1176391A (zh) 1998-03-18
EP0314402A2 (en) 1989-05-03
HK105996A (en) 1996-06-28
JPH0698020B2 (ja) 1994-12-07
AU2782789A (en) 1989-05-23
DE3886760D1 (de) 1994-02-10
NZ226692A (en) 1991-06-25
DK169627B1 (da) 1994-12-27
PT88847B (pt) 1993-01-29
ES2061736T3 (es) 1994-12-16
IE883213L (en) 1989-04-26
KR890701632A (ko) 1989-12-21
EP0375743B1 (en) 1993-12-29
US5041381A (en) 1991-08-20
WO1989003846A3 (en) 1989-05-18
WO1989003846A2 (en) 1989-05-05

Similar Documents

Publication Publication Date Title
IL88145A0 (en) Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
US5035994B1 (en) Human stem cells and monoclonal antibodies
US5130144B1 (en) Human stem cells and monoclonal antibodies
IL108199A0 (en) Monoclonal antibodies against the human il-4 receptor and hybridomas producing the same
EP0240344A3 (en) Monoclonal antibodies and their use
GB8910395D0 (en) Human monoclonal antibody and hybridoma producing the same
IL90017A0 (en) Monoclonal antibodies
EP0285511A3 (en) Monoclonal antibodies and their uses
ZA898777B (en) Monoclonal antibodies
IL92232A0 (en) Anti-fucosylceramide monoclonal antibody
GB8722020D0 (en) Human anti-rh(d)monoclonal antibodies
GB8722019D0 (en) Human anti-rh(d)monoclonal antibodies
GB8616174D0 (en) Monoclonal antibodies
EP0363712A3 (en) Hybrid monoclonal antibodies, their production and use
ZA89258B (en) Monoclonal antibodies
GB8901832D0 (en) Human monoclonal antibody and its production and use
GB8820036D0 (en) Monoclonal antibodies
GB2207921B (en) Monoclonal antibody to omega-gliadin and hybridoma thereof
GB8830115D0 (en) Monoclonal antibody and preparation and use thereof
EP0407586A4 (en) Human monoclonal antibody and process for its preparation
AU2546088A (en) Human monoclonal antibody against aspergilli
GB8610202D0 (en) Monoclonal antibodies
EP0252768A3 (en) Anti-lafora body monoclonal antibody
AU5852094A (en) Monoclonal antibodies against the human interleukin-4 receptor and hybridomas producing the same
EP0336441A3 (en) Anti-cpbii monoclonal antibody

Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force