DK101890D0 - Monoklonale antistoffer mod human interleukin-4 og hybridomaer, der producerer saadanne - Google Patents

Monoklonale antistoffer mod human interleukin-4 og hybridomaer, der producerer saadanne

Info

Publication number
DK101890D0
DK101890D0 DK101890A DK101890A DK101890D0 DK 101890 D0 DK101890 D0 DK 101890D0 DK 101890 A DK101890 A DK 101890A DK 101890 A DK101890 A DK 101890A DK 101890 D0 DK101890 D0 DK 101890D0
Authority
DK
Denmark
Prior art keywords
hybridomaes
producing
monoclonal antibodies
antibodies against
against human
Prior art date
Application number
DK101890A
Other languages
English (en)
Other versions
DK101890A (da
DK169627B1 (da
Inventor
John S Abrams
Isabelle Chretien
Frank D Lee
Michael K Pearce
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Publication of DK101890D0 publication Critical patent/DK101890D0/da
Publication of DK101890A publication Critical patent/DK101890A/da
Application granted granted Critical
Publication of DK169627B1 publication Critical patent/DK169627B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/247—IL-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK101890A 1987-10-26 1990-04-25 Monoklonale antistoffer mod human interleukin-4, hybridomaer producerende sådanne, fremgangsmåde og sæt til påvisning af human interleukin-4 samt fremgangsmåde til immunoprensning af human interleukin-4 DK169627B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/113,623 US5041381A (en) 1986-07-03 1987-10-26 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
US11362387 1987-10-26
PCT/US1988/003631 WO1989003846A2 (en) 1987-10-26 1988-10-21 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
US8803631 1988-10-21

Publications (3)

Publication Number Publication Date
DK101890D0 true DK101890D0 (da) 1990-04-25
DK101890A DK101890A (da) 1990-04-25
DK169627B1 DK169627B1 (da) 1994-12-27

Family

ID=22350540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK101890A DK169627B1 (da) 1987-10-26 1990-04-25 Monoklonale antistoffer mod human interleukin-4, hybridomaer producerende sådanne, fremgangsmåde og sæt til påvisning af human interleukin-4 samt fremgangsmåde til immunoprensning af human interleukin-4

Country Status (18)

Country Link
US (1) US5041381A (da)
EP (2) EP0314402A3 (da)
JP (1) JPH0698020B2 (da)
KR (1) KR930008112B1 (da)
CN (2) CN1032816A (da)
AU (1) AU611750B2 (da)
CA (1) CA1335653C (da)
DE (1) DE3886760T2 (da)
DK (1) DK169627B1 (da)
ES (1) ES2061736T3 (da)
HK (1) HK105996A (da)
IE (1) IE62491B1 (da)
IL (1) IL88145A0 (da)
MY (1) MY108526A (da)
NZ (1) NZ226692A (da)
PT (1) PT88847B (da)
WO (1) WO1989003846A2 (da)
ZA (1) ZA887987B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700915A (en) * 1985-11-19 1997-12-23 Schering Corporations Human interleukin immunopurification processes
ES2058490T3 (es) * 1988-02-02 1994-11-01 Schering Biotech Corp Metodo de reducir respuestas de inmunoglobulina e.
JPH05503098A (ja) * 1989-12-15 1993-05-27 カイロン　コーポレイション セプシスの処理のためのサイトカイン抗体
GB8928501D0 (en) * 1989-12-18 1990-02-21 Unilever Plc Reagents
IL96714A0 (en) * 1989-12-20 1991-09-16 Schering Corp Antibody antagonists of human interleukin-4
US5132109A (en) * 1990-10-05 1992-07-21 Ludwig Institute For Cancer Research Method for inhibiting production of ige and method for enhancing production of igg using interleukin 9 and inhibitors thereof
DE4137333A1 (de) * 1991-11-13 1993-05-19 W Prof Dr Sebald Therapeutische mittel, die antagonisten oder partielle agonisten des humanen interleukin 4 sind oder diese enthalten, hil-4-mutantenproteine sowie vefahren zu deren herstellung
US5863537A (en) * 1992-02-19 1999-01-26 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US5714146A (en) * 1992-08-26 1998-02-03 Board Of Regents Of The University Of Washington IL-4 bone therapy
US5928904A (en) * 1993-09-07 1999-07-27 Smithkline Beecham Corporation DNA encoding recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US5914110A (en) * 1993-09-07 1999-06-22 Smithkline Beecham Corporation Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US20020193575A1 (en) * 1993-09-07 2002-12-19 Smithkline Beecham P.L.C. Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
NZ274338A (en) * 1993-09-07 1998-02-26 Smithkline Beecham Corp Chimeric and humanised il-4 monoclonal antibodies and their use
US5959085A (en) * 1993-11-23 1999-09-28 Schering Corporation Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
EP0659766A1 (en) * 1993-11-23 1995-06-28 Schering-Plough Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
AU1744495A (en) * 1994-02-15 1995-08-29 T Cell Diagnostics, Inc. Immunoassay kit comprising universal reagents
US5597710A (en) * 1994-03-10 1997-01-28 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US5705154A (en) * 1995-03-08 1998-01-06 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
AUPN481295A0 (en) * 1995-08-16 1995-09-07 Medvet Science Pty. Ltd. Agonists of haemopoietic growth factors
US20020090682A1 (en) * 1995-10-23 2002-07-11 Tracy Willson Novel haemopoietin receptor and genetic sequences encoding same
DE16192152T1 (de) 2000-05-26 2020-08-06 Immunex Corporation Verwendung von interleukin-4 rezeptor (il-4r) antikörpern und zusammensetzungen davon
GB0210535D0 (en) * 2002-05-08 2002-06-19 Novartis Ag Organic compounds
JP2004045384A (ja) * 2002-05-22 2004-02-12 Matsushita Electric Ind Co Ltd 免疫学的測定方法、免疫学的測定装置、生体成分測定用トイレ、抗アルブミンモノクローナル抗体、それを産生する細胞株、およびアルブミン検出キット
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
AR050044A1 (es) * 2004-08-03 2006-09-20 Novartis Ag Anticuerpo especifico de il-4
US7608693B2 (en) * 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
GB0807214D0 (en) * 2008-04-21 2008-05-28 Belfast Health And Social Care Biomarkers
GB201210587D0 (en) * 2012-06-14 2012-08-01 Belfast Health And Social Care Trust Predictive biomarker
GB201210571D0 (en) * 2012-06-14 2012-08-01 Belfast Health And Social Care Trust Predictive biomarker
CN103421747B (zh) * 2013-09-09 2015-01-07 扬州大学 分泌牛il-4单克隆抗体的杂交瘤细胞株、其单克隆抗体及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255329A (en) 1973-10-02 1981-03-10 Syva Company Double receptor fluorescent immunoassay
US4342832A (en) 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US4431739A (en) * 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein
US4423147A (en) 1980-04-11 1983-12-27 Secher David S Monoclonal antibody to interferon-α
ATE5541T1 (de) 1980-06-20 1983-12-15 Battelle Memorial Institute Verfahren zur delignifizierung von holz und anderen lignocellulosematerialien.
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4355023A (en) 1980-09-30 1982-10-19 The Massachusetts General Hospital Antibody fragment compositions and process
US4599308A (en) 1981-10-06 1986-07-08 Hamer Dean H Protein from SV40 recombinants
US4470925A (en) 1982-05-05 1984-09-11 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
US4474493A (en) 1982-09-09 1984-10-02 Modular Systems, Inc. Dowel fastener and joints including same
EP0189405B1 (en) 1983-09-15 1989-02-22 University Of Bath Disinfection of contact lenses
US4731237A (en) 1983-11-07 1988-03-15 The Wistar Institute Immune response to virus induced by anti-idiotype antibodies
CA1255586A (en) 1984-07-24 1989-06-13 Hendrik M. Geysen Method of determining mimotopes
US4562003A (en) 1984-10-26 1985-12-31 California Biotechnology, Inc. Monoclonal antibodies against alveolar surfactant protein
EP0190711B1 (en) 1985-02-07 1989-04-26 Kowa Company, Ltd. Monoclonal antibodies to tissue plasminogen activator derived from human normal cells
WO1986006487A1 (en) 1985-04-22 1986-11-06 Commonwealth Serum Laboratories Commission Method for determining mimotopes
PT83761B (pt) * 1985-11-19 1989-06-30 Schering Biotech Corp Metodo para a producao de interleuquina-4 de mamifero

Also Published As

Publication number Publication date
DE3886760T2 (de) 1994-09-08
EP0375743A1 (en) 1990-07-04
EP0314402A3 (en) 1989-06-07
JPH03503118A (ja) 1991-07-18
IL88145A0 (en) 1989-06-30
IE62491B1 (en) 1995-02-08
MY108526A (en) 1996-10-31
CN1032816A (zh) 1989-05-10
AU611750B2 (en) 1991-06-20
KR930008112B1 (ko) 1993-08-26
CA1335653C (en) 1995-05-23
DK101890A (da) 1990-04-25
ZA887987B (en) 1990-06-27
CN1176391A (zh) 1998-03-18
EP0314402A2 (en) 1989-05-03
HK105996A (en) 1996-06-28
JPH0698020B2 (ja) 1994-12-07
AU2782789A (en) 1989-05-23
DE3886760D1 (de) 1994-02-10
NZ226692A (en) 1991-06-25
DK169627B1 (da) 1994-12-27
PT88847B (pt) 1993-01-29
ES2061736T3 (es) 1994-12-16
IE883213L (en) 1989-04-26
KR890701632A (ko) 1989-12-21
EP0375743B1 (en) 1993-12-29
US5041381A (en) 1991-08-20
WO1989003846A3 (en) 1989-05-18
WO1989003846A2 (en) 1989-05-05

Similar Documents

Publication Publication Date Title
DK101890D0 (da) Monoklonale antistoffer mod human interleukin-4 og hybridomaer, der producerer saadanne
NO884795D0 (no) Rekombinant, humant immunoglobulin og fremgangsmaate for fremstilling av dette.
NO921863L (no) Antistoffer og anvendelse derav
DK166087D0 (da) Proteiner og fremgangsmaade til fremstilling deraf
NO882385L (no) Polypeptid og produksjon derav.
NO863631L (no) Effektive hologrammer og fremgangsmaate for fremstilling derav.
NO843294L (no) Monokloklonat antistoff, dets fremstilling og anvendelse
NO880049L (no) Logging og fremgangsmaate derved.
DK511884A (da) Leukotrienantagonister og fremgangsmaade til fremstilling deraf
DK169987D0 (da) Human tumor-associated antigen, ca-ou1
NO170691C (no) Onkofoetale spesifikke monoklonale antistoffer og anvendelse derav
DK203087D0 (da) Proteiner og fremgangsmaade til fremstilling deraf
DK331784A (da) Naturligt humant interleukin-2 og fremgangsmaader til fremstilling deraf
NO881902D0 (no) Sopparoma og fremstilling derav.
DK34491A (da) Ekstruderet, biaksialt strakt skumplastroer og fremgangsmaade til fremstilling deraf
DK402888D0 (da) Antistoffer mod c5a og anvendelse deraf
DK585988A (da) Isopolypeptider og fremgangsmaade til fremstilling deraf
NO893818D0 (no) Produksjon og anvendelse av hybride, monoklonale antistoffer.
NO842155L (no) Meta- og para-isopropenyl-alfa,alfa-dimetylbenzylamin, og fremgangsmaate for fremstilling derav
DK265288A (da) Oximino-ether-forbindelser og fremgangsmaade til fremstilling deraf
DK8089D0 (da) Monoclonale antistoffer, deres fremstilling og anvendelse.
NO176614C (no) Monoklonalt antistoff og cellelinje som produserer antistoff
DK20687D0 (da) Polypeptidforbindelser og fremgangsmaade til fremstilling deraf
DK181183D0 (da) Cykliske imidatestere og fremgangsmade til fremstilling deraf
DK287288D0 (da) Polypeptid og fremgangmaade til fremstilling deraf

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PPF Opposition filed
PUG Patent revoked