DK511884A - Leukotrienantagonister og fremgangsmaade til fremstilling deraf - Google Patents

Leukotrienantagonister og fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK511884A
DK511884A DK511884A DK511884A DK511884A DK 511884 A DK511884 A DK 511884A DK 511884 A DK511884 A DK 511884A DK 511884 A DK511884 A DK 511884A DK 511884 A DK511884 A DK 511884A
Authority
DK
Denmark
Prior art keywords
procedures
producing
leukotrien
antagonists
leukotrien antagonists
Prior art date
Application number
DK511884A
Other languages
English (en)
Other versions
DK511884D0 (da
Inventor
Richard Frenette
Masatoshi Kakushima
Joshua Rokach
Robert N Young
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Publication of DK511884D0 publication Critical patent/DK511884D0/da
Publication of DK511884A publication Critical patent/DK511884A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK511884A 1983-10-27 1984-10-26 Leukotrienantagonister og fremgangsmaade til fremstilling deraf DK511884A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54601383A 1983-10-27 1983-10-27
US57316984A 1984-01-23 1984-01-23

Publications (2)

Publication Number Publication Date
DK511884D0 DK511884D0 (da) 1984-10-26
DK511884A true DK511884A (da) 1985-04-28

Family

ID=27068091

Family Applications (1)

Application Number Title Priority Date Filing Date
DK511884A DK511884A (da) 1983-10-27 1984-10-26 Leukotrienantagonister og fremgangsmaade til fremstilling deraf

Country Status (5)

Country Link
EP (1) EP0140684B1 (da)
CA (1) CA1254578A (da)
DE (1) DE3482685D1 (da)
DK (1) DK511884A (da)
ES (1) ES537023A0 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1309557C (en) 1985-06-18 1992-10-27 Robert N. Young Leukotriene antagonists
US4885309A (en) * 1986-08-01 1989-12-05 Hoffmann-La Roche Inc. Therapeutic treatment of leukotriene-mediated dermal inflammation by topical administration of 3,4-dihydro-2H-1-benzopyran derivatives
IL84796A (en) * 1986-12-17 1992-03-29 Merck Frosst Canada Inc Substituted n-benzyl-indoles and pharmaceutical compositions containing them
US4906658A (en) * 1987-04-21 1990-03-06 Merck Frosst Canada, Inc. Fluoro-sulfones
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
ZA911453B (en) * 1990-03-19 1991-11-27 Squibb & Sons Inc Method of protecting against and/or treating ulcerative gastrointestinal conditions using a thromoboxane,a2 receptor antagonist and combination useful in preventing and/or treating ulcers and/or inflammation
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
DK0544488T3 (da) * 1991-11-25 1998-04-06 Lilly Co Eli Substituerede phenylphenolleukotrienantagonister
CN1035001C (zh) * 1993-01-02 1997-05-28 伊莱利利公司 取代的苯基苯酚基白三烯拮抗物
US5409944A (en) * 1993-03-12 1995-04-25 Merck Frosst Canada, Inc. Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
ES2079997A1 (es) * 1993-06-15 1996-01-16 Lilly Co Eli Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos.
US5410054A (en) * 1993-07-20 1995-04-25 Merck Frosst Canada, Inc. Heteroaryl quinolines as inhibitors of leukotriene biosynthesis
WO1996023786A1 (en) * 1995-01-31 1996-08-08 Merck Frosst Canada Inc. 5-methanesulfonamido-3h-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2
WO2001054684A1 (fr) * 2000-01-26 2001-08-02 Kyorin Pharmaceutical Co., Ltd. Gouttes ophtalmologiques
CA2707360A1 (en) 2007-06-20 2008-12-24 Merck Sharp & Dohme Corp. Diphenyl substituted alkanes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2058785B (en) * 1979-09-05 1983-05-25 Glaxo Group Ltd Phenol derivatives
DE3265715D1 (en) * 1981-03-24 1985-10-03 Fisons Plc Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them
US4499299A (en) * 1981-12-30 1985-02-12 Ici Americas Inc. Pharmaceutically active phenylcarboxylic acid derivatives
DE3366107D1 (en) * 1982-09-30 1986-10-16 Merck Frosst Canada Inc Leukotriene antagonists, their production, and compositions containing them

Also Published As

Publication number Publication date
EP0140684B1 (en) 1990-07-11
ES8602588A1 (es) 1985-12-01
ES537023A0 (es) 1985-12-01
EP0140684A2 (en) 1985-05-08
CA1254578A (en) 1989-05-23
DE3482685D1 (de) 1990-08-16
EP0140684A3 (en) 1986-07-23
DK511884D0 (da) 1984-10-26

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