ES2079997A1 - Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos. - Google Patents

Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos.

Info

Publication number
ES2079997A1
ES2079997A1 ES09301322A ES9301322A ES2079997A1 ES 2079997 A1 ES2079997 A1 ES 2079997A1 ES 09301322 A ES09301322 A ES 09301322A ES 9301322 A ES9301322 A ES 9301322A ES 2079997 A1 ES2079997 A1 ES 2079997A1
Authority
ES
Spain
Prior art keywords
leucotriene
antagonist
pharmaceutical formulations
substituted phenyl
phenyl phenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
ES09301322A
Other languages
English (en)
Inventor
Stephen Richard Baker
Robert Delane Dillard
Paul Edward Floreancig
Jason Scott Sawyer
Michael Joseph Sofia
Elisabeth A Schmittling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority to ES09301322A priority Critical patent/ES2079997A1/es
Publication of ES2079997A1 publication Critical patent/ES2079997A1/es
Withdrawn legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPUESTOS DE FENIL FENOL SUSTITUIDOS ANTAGONISTAS DE LEUCOTRIENO, PROCEDIMIENTO PARA SU OBTENCION Y FORMULACIONES FARMACEUTICAS DE LOS MISMOS. ANTAGONISTAS QUE TIENEN UNA ESTRUCTURA FENIL FENOL SUSTITUIDA O UNA ESTRUCTURA BIFENIL FENOLICA SUSTITUIDA Y VARIOS DERIVADOS DE ELLOS, QUE SON ANTAGONISTAS ESPECIFICOS DE LEUCOTRIENOS. SE DESCRIBEN SUS ESTRUCTURAS, USO Y SINTESIS. ADEMAS, SE DESCRIBEN FORMULACIONES FARMACEUTICAS PARA USO EN APLICACIONES QUE TRATAN ENFERMEDADES O CONDICIONES CARACTERIZADAS POR LIBERACION EXCESIVA DE LEUCOTRIENO B4, UNO DE LOS METABOLITOS DEL ACIDO ARAQUIDONICO. LAS ESTRUCTURAS PRIMARIAS ANTAGONISTICAS DE LTB4 SE REPRESENTAN COMO FORMULA I, EN LA QUE R1, R2, R3, R4, X, Y, Z Y A SE DESCRIBEN EN DETALLE EN ESTA SOLICITUD. ESTA INVENCION PROPORCIONA TAMBIEN UN PROCEDIMIENTO PARA PREPARAR COMPUESTOS INTERMEDIOS DE LA FORMULA XI, EN LA QUE R21, R22 Y R23 Y T SON COMO SE DESCRIBEN EN ESTA SOLICITUD.
ES09301322A 1993-06-15 1993-06-15 Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos. Withdrawn ES2079997A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES09301322A ES2079997A1 (es) 1993-06-15 1993-06-15 Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09301322A ES2079997A1 (es) 1993-06-15 1993-06-15 Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos.

Publications (1)

Publication Number Publication Date
ES2079997A1 true ES2079997A1 (es) 1996-01-16

Family

ID=8282196

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09301322A Withdrawn ES2079997A1 (es) 1993-06-15 1993-06-15 Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos.

Country Status (1)

Country Link
ES (1) ES2079997A1 (es)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652646A (en) * 1966-03-31 1972-03-28 Ici Ltd Carboxylic acid derivatives
US3755603A (en) * 1970-07-01 1973-08-28 Syntex Corp Biphenylyloxyacetic acids in pharmaceutical compositions
EP0028063A1 (en) * 1979-09-05 1981-05-06 Glaxo Group Limited Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them
ES8302623A1 (es) * 1981-11-24 1983-02-01 Ausonia Farma Srl "procedimiento para la preparacion del acido (2',4'-difluoro-4-bifenil)-oxipropionico".
EP0140684A2 (en) * 1983-10-27 1985-05-08 Merck Frosst Canada Inc. Leukotriene antagonists
EP0544488A2 (en) * 1991-11-25 1993-06-02 Eli Lilly And Company Substituted phenyl phenol leukotriene antagonists

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652646A (en) * 1966-03-31 1972-03-28 Ici Ltd Carboxylic acid derivatives
US3755603A (en) * 1970-07-01 1973-08-28 Syntex Corp Biphenylyloxyacetic acids in pharmaceutical compositions
EP0028063A1 (en) * 1979-09-05 1981-05-06 Glaxo Group Limited Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them
ES8302623A1 (es) * 1981-11-24 1983-02-01 Ausonia Farma Srl "procedimiento para la preparacion del acido (2',4'-difluoro-4-bifenil)-oxipropionico".
EP0140684A2 (en) * 1983-10-27 1985-05-08 Merck Frosst Canada Inc. Leukotriene antagonists
EP0544488A2 (en) * 1991-11-25 1993-06-02 Eli Lilly And Company Substituted phenyl phenol leukotriene antagonists

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Legal Events

Date Code Title Description
FA2A Application withdrawn

Effective date: 19960424