DE3482685D1 - Leukotrien-antagonisten. - Google Patents

Leukotrien-antagonisten.

Info

Publication number
DE3482685D1
DE3482685D1 DE8484307390T DE3482685T DE3482685D1 DE 3482685 D1 DE3482685 D1 DE 3482685D1 DE 8484307390 T DE8484307390 T DE 8484307390T DE 3482685 T DE3482685 T DE 3482685T DE 3482685 D1 DE3482685 D1 DE 3482685D1
Authority
DE
Germany
Prior art keywords
leukotria
antagonists
leukotria antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484307390T
Other languages
English (en)
Inventor
Richard Frenette
Joshua Rokach
Robert N Young
Masatoshi Kakushima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Merck Frosst Canada and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada and Co filed Critical Merck Frosst Canada and Co
Application granted granted Critical
Publication of DE3482685D1 publication Critical patent/DE3482685D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8484307390T 1983-10-27 1984-10-26 Leukotrien-antagonisten. Expired - Lifetime DE3482685D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54601383A 1983-10-27 1983-10-27
US57316984A 1984-01-23 1984-01-23

Publications (1)

Publication Number Publication Date
DE3482685D1 true DE3482685D1 (de) 1990-08-16

Family

ID=27068091

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484307390T Expired - Lifetime DE3482685D1 (de) 1983-10-27 1984-10-26 Leukotrien-antagonisten.

Country Status (5)

Country Link
EP (1) EP0140684B1 (de)
CA (1) CA1254578A (de)
DE (1) DE3482685D1 (de)
DK (1) DK511884A (de)
ES (1) ES537023A0 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1309557C (en) 1985-06-18 1992-10-27 Robert N. Young Leukotriene antagonists
US4885309A (en) * 1986-08-01 1989-12-05 Hoffmann-La Roche Inc. Therapeutic treatment of leukotriene-mediated dermal inflammation by topical administration of 3,4-dihydro-2H-1-benzopyran derivatives
IL84796A (en) * 1986-12-17 1992-03-29 Merck Frosst Canada Inc Substituted n-benzyl-indoles and pharmaceutical compositions containing them
US4906658A (en) * 1987-04-21 1990-03-06 Merck Frosst Canada, Inc. Fluoro-sulfones
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
ZA911453B (en) * 1990-03-19 1991-11-27 Squibb & Sons Inc Method of protecting against and/or treating ulcerative gastrointestinal conditions using a thromoboxane,a2 receptor antagonist and combination useful in preventing and/or treating ulcers and/or inflammation
HU222486B1 (hu) * 1991-11-25 2003-07-28 Eli Lilly And Co. Leukotrién antagonista szubsztituált fenil-fenol-származékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
CN1035001C (zh) * 1993-01-02 1997-05-28 伊莱利利公司 取代的苯基苯酚基白三烯拮抗物
US5409944A (en) * 1993-03-12 1995-04-25 Merck Frosst Canada, Inc. Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
ES2079997A1 (es) * 1993-06-15 1996-01-16 Lilly Co Eli Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos.
US5410054A (en) * 1993-07-20 1995-04-25 Merck Frosst Canada, Inc. Heteroaryl quinolines as inhibitors of leukotriene biosynthesis
AU4479096A (en) * 1995-01-31 1996-08-21 Merck Frosst Canada Inc. 5-methanesulfonamido-3h-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2
EP1250924A4 (de) * 2000-01-26 2007-03-14 Kyorin Seiyaku Kk Augentropfen
AU2008266960A1 (en) 2007-06-20 2008-12-24 Merck Sharp & Dohme Corp. Diphenyl substituted alkanes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2058785B (en) * 1979-09-05 1983-05-25 Glaxo Group Ltd Phenol derivatives
EP0061800B1 (de) * 1981-03-24 1985-08-28 FISONS plc Anti-SRS-A-Carbonsäurederivate, Verfahren zu deren Herstellung und pharmazeutische Formulierungen, die jene enthalten
IE54269B1 (en) * 1981-12-30 1989-08-02 Ici America Inc Pharmaceutically active phenylcarboxylic acid derivatives
ATE22072T1 (de) * 1982-09-30 1986-09-15 Merck Frosst Canada Inc Leukotrienantagonisten, deren herstellung und diese enthaltende zusammensetzungen.

Also Published As

Publication number Publication date
DK511884D0 (da) 1984-10-26
ES8602588A1 (es) 1985-12-01
EP0140684A3 (en) 1986-07-23
DK511884A (da) 1985-04-28
EP0140684A2 (de) 1985-05-08
EP0140684B1 (de) 1990-07-11
ES537023A0 (es) 1985-12-01
CA1254578A (en) 1989-05-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee