IL87196A - Serum free medium for the growthof insect cells and expressionof products thereby - Google Patents
Serum free medium for the growthof insect cells and expressionof products therebyInfo
- Publication number
- IL87196A IL87196A IL87196A IL8719688A IL87196A IL 87196 A IL87196 A IL 87196A IL 87196 A IL87196 A IL 87196A IL 8719688 A IL8719688 A IL 8719688A IL 87196 A IL87196 A IL 87196A
- Authority
- IL
- Israel
- Prior art keywords
- serum
- products
- serum free
- insect cells
- free medium
- Prior art date
Links
- 241000238631 Hexapoda Species 0.000 title abstract 4
- 239000012679 serum free medium Substances 0.000 title abstract 2
- 230000010261 cell growth Effects 0.000 abstract 2
- 210000002966 serum Anatomy 0.000 abstract 2
- 239000004017 serum-free culture medium Substances 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0601—Invertebrate cells or tissues, e.g. insect cells; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/74—Undefined extracts from fungi, e.g. yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
- C12N2500/84—Undefined extracts from animals from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/077,303 US5024947A (en) | 1987-07-24 | 1987-07-24 | Serum free media for the growth on insect cells and expression of products thereby |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL87196A0 IL87196A0 (en) | 1988-12-30 |
| IL87196A true IL87196A (en) | 1993-04-04 |
Family
ID=22137290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL87196A IL87196A (en) | 1987-07-24 | 1988-07-22 | Serum free medium for the growthof insect cells and expressionof products thereby |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5024947A (de) |
| EP (1) | EP0380495B1 (de) |
| JP (1) | JP2898291B2 (de) |
| AT (1) | ATE105856T1 (de) |
| AU (1) | AU2126688A (de) |
| CA (1) | CA1309679C (de) |
| DE (1) | DE3889665T2 (de) |
| IE (1) | IE64262B1 (de) |
| IL (1) | IL87196A (de) |
| WO (1) | WO1989001028A1 (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5760203A (en) * | 1988-08-10 | 1998-06-02 | Chiron Corporation | Gap gene sequences |
| US5763573A (en) * | 1988-08-10 | 1998-06-09 | Chiron Corporation | GTPase activating protein fragments |
| US5272063A (en) * | 1988-11-22 | 1993-12-21 | Syntex (U.S.A.) Inc. | Process of making human nerve growth factor |
| CA2091443A1 (en) * | 1990-09-25 | 1992-03-26 | Luciano Ramos | Medium for culture of mammalian cells |
| HK1008751A1 (en) * | 1990-09-25 | 1999-05-14 | Smithkline Beecham Corporation | Media for culture of drosophila cells |
| JPH04228066A (ja) * | 1990-10-23 | 1992-08-18 | Rikagaku Kenkyusho | 外来遺伝子発現用培養細胞 |
| JPH0671432B2 (ja) * | 1991-03-20 | 1994-09-14 | 株式会社ミドリ十字 | ヒト血清アルブミンの製造方法 |
| US5318898A (en) * | 1991-04-02 | 1994-06-07 | Genetics Institute, Inc. | Production of recombinant bone-inducing proteins |
| DE69227519T2 (de) * | 1991-09-06 | 1999-06-02 | Research Development Foundation, Carson City, Nev. | Dna-sequenzen kodierend für das polypeptid gelonin |
| US5298418A (en) * | 1991-09-16 | 1994-03-29 | Boyce Thompson Institute For Plant Research, Inc. | Cell line isolated from larval midgut tissue of Trichoplusia ni |
| US5405770A (en) * | 1993-01-21 | 1995-04-11 | The United States Of America As Represented By The Secretary Of Agriculture | Heliothis subflexa cell line for the production of baculoviruses |
| US5348877A (en) * | 1993-03-12 | 1994-09-20 | Boyce Thompson Institute For Plant Research, Inc. | Method of adapting anchorage-dependent cell lines to suspension conditions |
| WO1994026087A2 (en) * | 1993-05-14 | 1994-11-24 | Connor Kim C O | Recombinant protein production and insect cell culture and process |
| US5550019A (en) | 1993-05-26 | 1996-08-27 | La Jolla Cancer Research Foundation | Methods of identifying compounds which alter apoptosis |
| US5426045A (en) * | 1993-12-16 | 1995-06-20 | Sea Run Holdings, Inc. | Method for culturing mammalian cells in a medium containing fish serum |
| US5641678A (en) * | 1994-01-18 | 1997-06-24 | Smithkline Beecham Corporation | Serum-free culture medium for drosphila insect cells |
| US5498540A (en) * | 1994-02-23 | 1996-03-12 | Sea Run Holdings, Inc. | Method for culturing insect cells in a medium containing fish serum |
| US6403375B1 (en) * | 1994-08-24 | 2002-06-11 | Boyce Thompson Institute For Plant Research, Inc. | Establishment of Trichoplusia ni cell lines in serum-free medium for recombinant protein and baculovirus production |
| FR2726574B1 (fr) * | 1994-11-04 | 1997-01-17 | Univ Paris Curie | Procede de dissociation des cellules eucaryotes en culture |
| US5728580A (en) * | 1996-02-20 | 1998-03-17 | Cornell Research Foundation, Inc. | Methods and culture media for inducing single cell suspension in insect cell lines |
| DE69717092T2 (de) | 1996-03-01 | 2003-07-24 | Novo Nordisk A/S, Bagsvaerd | Gebrauch einer pharmazeutischen Zusammensetzung, enthaltend ein appetitzügelndes Peptid |
| EP0891419A4 (de) | 1996-03-12 | 2000-03-01 | Life Technologies Inc | Nährstoffzusatz für hematopoetische zellkulturen |
| EP1482031B1 (de) * | 1996-08-30 | 2015-10-28 | Life Technologies Corporation | Serumfreies Kulturmedium für Säugerzellen und seine Verwendung |
| US6309864B1 (en) | 1997-04-03 | 2001-10-30 | Yoshitomi Pharmaceutical Industries, Ltd. | Process for producing foreign proteins |
| US5804420A (en) * | 1997-04-18 | 1998-09-08 | Bayer Corporation | Preparation of recombinant Factor VIII in a protein free medium |
| US6066602A (en) * | 1997-08-07 | 2000-05-23 | Becton Dickinson And Company | Waterborne non-silicone lubricant comprising phospholipid and polyether |
| US6051401A (en) * | 1998-07-28 | 2000-04-18 | Bayer Corporation | Methods and constructs for protein expression |
| AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| US6670184B2 (en) * | 2000-06-23 | 2003-12-30 | Basf Ag | Method for producing a lipid emulsion for use in insect cell culture |
| DE10050091A1 (de) * | 2000-10-09 | 2002-04-25 | Biotechnolog Forschung Gmbh | Casein-Peptidfragmente mit wachstumsbeeinflußender Aktivität auf Zellkulturen |
| US7445924B2 (en) * | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| MXPA03008590A (es) | 2001-03-22 | 2003-12-08 | Novo Nordisk Healthcare Ag | Derivados del factor vii de coagulacion. |
| DE60225545T2 (de) * | 2001-05-07 | 2009-04-02 | National Research Council Of Canada, Ottawa | Verstärkte herstellung rekombinanter proteine mittels transienter transfektion von in suspension wachsenden säugerzellen |
| GB0123098D0 (en) * | 2001-09-26 | 2001-11-14 | Lonza Biologics Plc | Use of aminoglycoside resistance gene |
| US6943023B2 (en) * | 2002-03-06 | 2005-09-13 | National Institute Of Agrobiological Sciences | Insect cell primary culture medium, extra cellular matrix, and process of preparing an insect culture cell line in a short period of time using the medium and matrix |
| JP2005537793A (ja) | 2002-09-05 | 2005-12-15 | バヴァリアン・ノルディック・アクティーゼルスカブ | 無血清条件下で初代細胞を培養する方法及びウイルスを増幅させる方法 |
| ES2381110T3 (es) | 2003-09-09 | 2012-05-23 | Novo Nordisk Health Care Ag | Polipéptidos de factor VII de coagulación |
| US7087369B2 (en) * | 2003-12-17 | 2006-08-08 | The Regents Of The University Of California | Cornea preservation medium |
| US20070281332A1 (en) | 2004-02-13 | 2007-12-06 | Allan Svendsen | Protease Variants |
| US7422875B2 (en) * | 2004-07-20 | 2008-09-09 | Board Of Regents Of The University Of Nebraska | Compositions and methods for increasing protein production |
| AU2006237329B2 (en) | 2005-04-18 | 2012-04-12 | Novo Nordisk A/S | IL-21 variants |
| JP5690047B2 (ja) | 2005-09-14 | 2015-03-25 | ノボ ノルディスク ヘルス ケア アーゲー | ヒト凝固第vii因子ポリペプチド |
| SG10202007719TA (en) | 2008-12-05 | 2020-09-29 | Takeda Vaccines Inc | Compositions, methods and uses for inducing viral growth |
| US20120282285A1 (en) | 2009-07-17 | 2012-11-08 | Rigshospitalet | Masp isoforms as inhibitors of complement activation |
| CA2791841C (en) | 2010-03-05 | 2023-01-03 | Rigshospitalet | Chimeric inhibitor molecules of complement activation |
| AU2013217986B2 (en) | 2012-02-09 | 2017-04-27 | Var2 Pharmaceuticals Aps | Targeting of chondroitin sulfate glycans |
| CN104704118A (zh) | 2012-10-15 | 2015-06-10 | 诺和诺德保健Ag(股份有限公司) | 凝血因子vii多肽 |
| WO2014159831A1 (en) | 2013-03-13 | 2014-10-02 | Merck Sharp & Dohme Corp. | Adapted lepidopteran insect cells for the production of recombinant proteins |
| HRP20251426T1 (hr) | 2013-05-06 | 2026-01-02 | Scholar Rock, Inc. | Sastavi i postupci za modulaciju faktora rasta |
| KR102649950B1 (ko) * | 2013-10-03 | 2024-03-22 | 다케다 백신즈 인코포레이티드 | 세포주로부터 랍도바이러스를 탐지 및 제거하는 방법 |
| CN105441376B (zh) * | 2015-12-22 | 2018-03-20 | 肇庆大华农生物药品有限公司 | 一种用于培养病毒的无血清培养基及其制备方法 |
| WO2017195745A1 (ja) * | 2016-05-09 | 2017-11-16 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 培地、アルブミン非含有培地用添加剤および多能性幹細胞の培養方法 |
| US20210278406A1 (en) | 2018-07-13 | 2021-09-09 | Varct Diagnostic Aps | Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US30985A (en) * | 1860-12-18 | Thomas l | ||
| USRE30985E (en) * | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| DE3048289A1 (de) * | 1980-12-20 | 1982-07-29 | Hoechst Ag | "verfahren zur zuechtung von insektenzellen" |
| JPS5831989A (ja) * | 1981-08-13 | 1983-02-24 | Asahi Chem Ind Co Ltd | 正常二倍体細胞の培養方法 |
| DE3216163A1 (de) * | 1982-04-30 | 1983-11-03 | Behringwerke Ag | Kulturmedium und verfahren zur virusvermehrung in suspensionskultur |
| IE58011B1 (en) * | 1983-05-27 | 1993-06-16 | Texas A & M Univ Sys | Method for producing a recombinant baculovirus expression vector |
| ZA848495B (en) * | 1984-01-31 | 1985-09-25 | Idaho Res Found | Production of polypeptides in insect cells |
| US4485029A (en) * | 1984-03-19 | 1984-11-27 | Minnesota Mining And Manufacturing Company | Disinfecting method and compositions |
| US4752585A (en) * | 1985-12-17 | 1988-06-21 | Cetus Corporation | Oxidation-resistant muteins |
| JPH0615447B2 (ja) * | 1985-12-02 | 1994-03-02 | 進 前田 | ウイルスを利用した殺虫剤及びその調製法 |
-
1987
- 1987-07-24 US US07/077,303 patent/US5024947A/en not_active Expired - Fee Related
-
1988
- 1988-07-20 AU AU21266/88A patent/AU2126688A/en not_active Abandoned
- 1988-07-20 EP EP88906600A patent/EP0380495B1/de not_active Expired - Lifetime
- 1988-07-20 DE DE3889665T patent/DE3889665T2/de not_active Expired - Fee Related
- 1988-07-20 WO PCT/US1988/002443 patent/WO1989001028A1/en not_active Ceased
- 1988-07-20 AT AT88906600T patent/ATE105856T1/de not_active IP Right Cessation
- 1988-07-20 JP JP63506450A patent/JP2898291B2/ja not_active Expired - Lifetime
- 1988-07-20 CA CA000572548A patent/CA1309679C/en not_active Expired - Fee Related
- 1988-07-22 IE IE226488A patent/IE64262B1/en not_active IP Right Cessation
- 1988-07-22 IL IL87196A patent/IL87196A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2126688A (en) | 1989-03-01 |
| DE3889665D1 (de) | 1994-06-23 |
| IE64262B1 (en) | 1995-07-26 |
| JPH03500602A (ja) | 1991-02-14 |
| WO1989001028A1 (en) | 1989-02-09 |
| IL87196A0 (en) | 1988-12-30 |
| US5024947A (en) | 1991-06-18 |
| CA1309679C (en) | 1992-11-03 |
| DE3889665T2 (de) | 1994-11-03 |
| EP0380495A1 (de) | 1990-08-08 |
| ATE105856T1 (de) | 1994-06-15 |
| JP2898291B2 (ja) | 1999-05-31 |
| IE882264L (en) | 1989-01-24 |
| EP0380495B1 (de) | 1994-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC | Change of name of proprietor(s) | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |