IL85983A - Human somatomedin carrier protein subunits, antibodies against them, pharmaceutical compostitions containing them and their use in the preparation of medicaments - Google Patents

Human somatomedin carrier protein subunits, antibodies against them, pharmaceutical compostitions containing them and their use in the preparation of medicaments

Info

Publication number
IL85983A
IL85983A IL8598388A IL8598388A IL85983A IL 85983 A IL85983 A IL 85983A IL 8598388 A IL8598388 A IL 8598388A IL 8598388 A IL8598388 A IL 8598388A IL 85983 A IL85983 A IL 85983A
Authority
IL
Israel
Prior art keywords
carrier protein
human
growth
polypeptide
somatomedins
Prior art date
Application number
IL8598388A
Other languages
English (en)
Other versions
IL85983A0 (en
Original Assignee
Celtrix Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtrix Pharma filed Critical Celtrix Pharma
Publication of IL85983A0 publication Critical patent/IL85983A0/xx
Publication of IL85983A publication Critical patent/IL85983A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743Insulin-like growth factor binding protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL8598388A 1987-04-06 1988-04-05 Human somatomedin carrier protein subunits, antibodies against them, pharmaceutical compostitions containing them and their use in the preparation of medicaments IL85983A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3488587A 1987-04-06 1987-04-06

Publications (2)

Publication Number Publication Date
IL85983A0 IL85983A0 (en) 1988-09-30
IL85983A true IL85983A (en) 1994-10-07

Family

ID=21879212

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8598388A IL85983A (en) 1987-04-06 1988-04-05 Human somatomedin carrier protein subunits, antibodies against them, pharmaceutical compostitions containing them and their use in the preparation of medicaments

Country Status (11)

Country Link
EP (2) EP0308500B1 (da)
JP (1) JP2648951B2 (da)
AT (1) ATE90690T1 (da)
AU (1) AU627423B2 (da)
CA (1) CA1340295C (da)
DE (1) DE3881801T2 (da)
DK (1) DK677688D0 (da)
ES (1) ES2058341T3 (da)
IL (1) IL85983A (da)
WO (1) WO1988007863A1 (da)
ZA (1) ZA882407B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973115A (en) * 1987-05-15 1999-10-26 Amgen Inc. Method for potentiating and inhibiting insulin-like growth factor activity
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
JPH03504597A (ja) * 1988-04-12 1991-10-09 シナージェン,インコーポレーテッド インスリン様成長因子活性の強化および阻害方法
CA1341598C (en) * 1988-07-15 2009-09-29 Central Sydney Area Health Service Acid-labile sub-unit (als) of insulin-like growth factor binding proteincomplex
US6465423B1 (en) 1988-07-15 2002-10-15 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
US5324820A (en) * 1988-07-15 1994-06-28 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
WO1996002565A1 (en) * 1994-07-20 1996-02-01 Celtrix Pharmaceuticals, Inc. Igf/igfbp complex for promoting bone formation and for regulating bone remodeling
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
DK1141014T3 (da) 1999-01-06 2005-04-11 Genentech Inc Insulinlignende vækstfaktor (IGF) i mutantvariant
AU762047B2 (en) 1999-01-06 2003-06-19 Genentech Inc. Insulin-like growth factor (IGF) I mutant variants
ES2301547T3 (es) 2000-05-16 2008-07-01 Genentech, Inc. Tratamiento de trastornos del cartilago.
US7071300B2 (en) 2001-03-14 2006-07-04 Genentech, Inc. IGF antagonist peptides
WO2005016970A2 (en) 2003-05-01 2005-02-24 Imclone Systems Incorporated Fully human antibodies directed against the human insulin-like growth factor-1 receptor
ES2541673T3 (es) 2003-09-12 2015-07-23 Ipsen Biopharmaceuticals, Inc. Métodos para el tratamiento de la deficiencia de factor 1 de crecimiento similar a la insulina (IGF-1)
WO2005033132A2 (en) 2003-10-03 2005-04-14 Genentech, Inc. Igf binding proteins
BRPI0611984A2 (pt) 2005-06-17 2009-07-07 Imclone Systems Inc uso de anticorpos igf-ir para fabricação de um medicamento para tratar um tumor ósseo
JP5198289B2 (ja) 2006-02-03 2013-05-15 イムクローン・リミテッド・ライアビリティ・カンパニー 前立腺癌の治療用アジュバントとしてのigf−irアンタゴニスト
MX2020002744A (es) 2017-09-11 2020-10-01 Takeda Pharmaceuticals Co Metodos y composiciones para tratar enfermedades pulmonares cronicas.
AU2021364523A1 (en) 2020-10-19 2023-04-06 Oak Hill Bio Limited Compositions suitable for use in neonates
WO2023139115A1 (en) 2022-01-19 2023-07-27 Oak Hill Bio Limited Compositions and methods for reducing oxidation of igf‐1/igfbp
WO2023242440A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
WO2023242439A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Vascular stabilisation (preterm infants)
WO2023242442A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Method of maturing/differentiating neurons and/or modulating the vagus nerve

Also Published As

Publication number Publication date
JP2648951B2 (ja) 1997-09-03
EP0294021A1 (en) 1988-12-07
DK677688A (da) 1988-12-05
ZA882407B (en) 1988-09-28
EP0308500B1 (en) 1993-06-16
AU1702088A (en) 1988-11-04
WO1988007863A1 (en) 1988-10-20
DE3881801T2 (de) 1993-12-23
EP0308500A1 (en) 1989-03-29
DE3881801D1 (de) 1993-07-22
DK677688D0 (da) 1988-12-05
ATE90690T1 (de) 1993-07-15
CA1340295C (en) 1998-12-29
JPH01502986A (ja) 1989-10-12
IL85983A0 (en) 1988-09-30
ES2058341T3 (es) 1994-11-01
AU627423B2 (en) 1992-08-27

Similar Documents

Publication Publication Date Title
EP0308500B1 (en) Human somatomedin carrier protein subunits and process for producing them
US5200509A (en) Human somatomedin carrier protein subunits and process for producing them; recombinant DNA molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
Zapf et al. Serum levels of insulin-like growth factor (IGF) and its carrier protein in various metabolic disorders
CA2006322C (en) Recombinant dna molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
JPH03506030A (ja) インスリン様成長因子(igf)結合蛋白複合体の酸不安定サブユニット(als)
JP2819467B2 (ja) 新規なカルジオジラチン断片およびその製造方法
BREUER Stimulation of DNA Synthesis in Cartilage of Modified Placental Lactogen and Anabolic Hormones
JP2527896B2 (ja) ヒト骨由来インスリン様成長因子結合タンパク
JPH11506337A (ja) 骨刺激因子
DEVITO Comparison of brain and pituitary immunoreactive prolactin by peptide mapping and lectin affinity chromatography
Robbins et al. Products of therapeutic insulins in the blood of insulin-dependent (type I) diabetic patients
WO2003102180A1 (fr) Nouveaux peptides avec activite de production de camp
JP2803184B2 (ja) 酸性線維芽細胞成長因子の抗体,その用途およびペプチド
Ooi et al. Recognition of insulin-like-growth-factor-binding proteins in serum and amniotic fluid by an antiserum against a low-molecular-mass insulin-like-growth-factor-inhibitor/binding protein
JP2562892B2 (ja) インスリン結合活性を有するポリペプチド
WO1996019501A1 (en) Modulators of bone cell function and uses thereof
HARTREE Chapter Preparation and 0ne Properties of Human Growth Hormone
Brems et al. Asp B1 insulin analogs