IL85969A - 2-substituted-1'-desoxy-1'-(6-amino-9-purinyl)-beta-d-ribofuranuronic acid(thio)amides,their preparation and pharmaceutical compositions containing them - Google Patents

2-substituted-1'-desoxy-1'-(6-amino-9-purinyl)-beta-d-ribofuranuronic acid(thio)amides,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL85969A
IL85969A IL85969A IL8596988A IL85969A IL 85969 A IL85969 A IL 85969A IL 85969 A IL85969 A IL 85969A IL 8596988 A IL8596988 A IL 8596988A IL 85969 A IL85969 A IL 85969A
Authority
IL
Israel
Prior art keywords
desoxy
purinyl
thio
amides
beta
Prior art date
Application number
IL85969A
Other languages
English (en)
Other versions
IL85969A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL85969A0 publication Critical patent/IL85969A0/xx
Publication of IL85969A publication Critical patent/IL85969A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL85969A 1987-04-06 1988-04-04 2-substituted-1'-desoxy-1'-(6-amino-9-purinyl)-beta-d-ribofuranuronic acid(thio)amides,their preparation and pharmaceutical compositions containing them IL85969A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3711563 1987-04-06
DE3711564 1987-04-06
DE3711562 1987-04-06
DE3711561 1987-04-06

Publications (2)

Publication Number Publication Date
IL85969A0 IL85969A0 (en) 1988-09-30
IL85969A true IL85969A (en) 1992-03-29

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85969A IL85969A (en) 1987-04-06 1988-04-04 2-substituted-1'-desoxy-1'-(6-amino-9-purinyl)-beta-d-ribofuranuronic acid(thio)amides,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
JP (1) JPS63258892A (es)
KR (1) KR880012629A (es)
AT (1) AT393507B (es)
AU (1) AU609109B2 (es)
BE (1) BE1002151A5 (es)
CA (1) CA1326017C (es)
CH (1) CH676121A5 (es)
DK (1) DK183488A (es)
ES (1) ES2007177A6 (es)
FI (1) FI87463C (es)
FR (1) FR2613367A1 (es)
GB (1) GB2203149B (es)
HU (1) HU201955B (es)
IL (1) IL85969A (es)
IT (1) IT1219892B (es)
LU (1) LU87181A1 (es)
MY (1) MY102323A (es)
NL (1) NL8800862A (es)
NZ (1) NZ224131A (es)
PH (1) PH25424A (es)
PT (1) PT87153B (es)
SE (1) SE8801236A0 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
FI880405A (fi) * 1987-02-04 1988-08-05 Ciba Geigy Ag Adenosin-5'-karboxamidderivat.
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
DE69910213T2 (de) 1998-06-23 2004-07-01 Glaxo Group Ltd., Greenford 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivate
AU4343500A (en) 1999-04-16 2000-11-02 Schering Corporation Use of azetidinone compounds
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
US7863253B2 (en) * 2004-09-20 2011-01-04 Inotek Pharmaceuticals Corporation Purine Derivatives and methods of use thereof
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
FI880405A (fi) * 1987-02-04 1988-08-05 Ciba Geigy Ag Adenosin-5'-karboxamidderivat.

Also Published As

Publication number Publication date
ATA87388A (de) 1991-04-15
SE8801236L (sv) 1988-10-17
BE1002151A5 (fr) 1990-08-07
GB2203149A (en) 1988-10-12
NZ224131A (en) 1991-12-23
FI881571A0 (fi) 1988-04-05
DK183488A (da) 1988-10-07
JPS63258892A (ja) 1988-10-26
FI87463B (fi) 1992-09-30
ES2007177A6 (es) 1989-06-01
FI881571A (fi) 1988-10-07
PH25424A (es) 1991-07-01
PT87153A (pt) 1988-05-01
IT8847794A0 (it) 1988-03-30
AU609109B2 (en) 1991-04-26
SE8801236A0 (sv) 1988-10-17
LU87181A1 (fr) 1988-11-17
GB2203149B (en) 1991-02-13
CH676121A5 (es) 1990-12-14
NL8800862A (nl) 1988-11-01
DK183488D0 (da) 1988-04-05
SE8801236D0 (sv) 1988-04-05
AU1415188A (en) 1988-10-06
HU201955B (en) 1991-01-28
FR2613367A1 (fr) 1988-10-07
HUT48902A (en) 1989-07-28
AT393507B (de) 1991-11-11
MY102323A (en) 1992-05-28
GB8807750D0 (en) 1988-05-05
FI87463C (fi) 1993-01-11
CA1326017C (en) 1994-01-11
PT87153B (pt) 1992-07-31
KR880012629A (ko) 1988-11-28
IT1219892B (it) 1990-05-24
IL85969A0 (en) 1988-09-30

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Legal Events

Date Code Title Description
RH Patent void