IL87871A0 - Amino acid derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents

Amino acid derivatives,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL87871A0
IL87871A0 IL87871A IL8787188A IL87871A0 IL 87871 A0 IL87871 A0 IL 87871A0 IL 87871 A IL87871 A IL 87871A IL 8787188 A IL8787188 A IL 8787188A IL 87871 A0 IL87871 A0 IL 87871A0
Authority
IL
Israel
Prior art keywords
manufacture
amino acid
pharmaceutical compositions
compositions containing
acid derivatives
Prior art date
Application number
IL87871A
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL87871A0 publication Critical patent/IL87871A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
IL87871A 1987-10-06 1988-09-29 Amino acid derivatives,their manufacture and pharmaceutical compositions containing them IL87871A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH390387 1987-10-06

Publications (1)

Publication Number Publication Date
IL87871A0 true IL87871A0 (en) 1989-03-31

Family

ID=4265984

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87871A IL87871A0 (en) 1987-10-06 1988-09-29 Amino acid derivatives,their manufacture and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0310918A3 (en)
JP (1) JPH02256658A (en)
KR (1) KR890006572A (en)
AU (1) AU627156B2 (en)
DK (1) DK523288A (en)
FI (1) FI884598A (en)
HU (1) HUT49322A (en)
IL (1) IL87871A0 (en)
MC (1) MC1985A1 (en)
NO (1) NO884434L (en)
NZ (1) NZ226395A (en)
PT (1) PT88679A (en)
YU (1) YU185188A (en)
ZA (1) ZA887322B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU595309B2 (en) * 1986-05-09 1990-03-29 Dainippon Pharmaceutical Co. Ltd. Tripeptide derivatives
US4895834A (en) * 1986-12-15 1990-01-23 Warner-Lambert Company Renin inhibitors III
US5023236A (en) * 1988-04-07 1991-06-11 Corvas, Inc. Factor VII/VIIA active site inhibitors
EP0391180A3 (en) * 1989-04-04 1991-04-03 F. Hoffmann-La Roche Ag Peptide derivatives of amino acids having a renin-inhibiting effect
CA2012901A1 (en) * 1989-04-05 1990-10-05 Quirico Branca Amino acid derivatives
EP0417698B1 (en) * 1989-09-12 1996-03-13 Hoechst Aktiengesellschaft Amino acid derivatives having renin-inhibiting activity, process for their preparation, agents containing them, and their use
DE4008403A1 (en) * 1990-03-16 1991-09-19 Merck Patent Gmbh GLYKOLSAEUREDERIVATE
US5516784A (en) * 1991-08-13 1996-05-14 Schering Corporation Anti-HIV (AIDS) agents
US5422349A (en) * 1992-08-14 1995-06-06 G. D. Seale & Co. Morpholino-oxazinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
WO1994017096A1 (en) * 1993-01-17 1994-08-04 Schering Corporation Peptides having anti-hiv activity
US5563127A (en) * 1993-03-24 1996-10-08 The Dupont Merck Pharmaceutical Company Boronic acid and ester inhibitors of thrombin
FR2741066B1 (en) * 1995-11-14 1997-12-12 Rhone Poulenc Rorer Sa NEW TRANSFECTION AGENTS AND THEIR PHARMACEUTICAL APPLICATIONS
FR2752422B1 (en) * 1996-08-16 1998-11-06 Lipha PHARMACEUTICAL COMPOSITION CONTAINING 4-OXO-BUTANOIC ACIDS
WO1999058505A2 (en) * 1998-05-12 1999-11-18 Warner-Lambert Company Combinations of protein farnesyltransferase and hmg coa reductase inhibitors and their use to treat cancer
LT2494993T (en) * 2007-05-04 2018-12-27 Marina Biotech, Inc. Amino acid lipids and uses thereof
GB0919194D0 (en) 2009-11-02 2009-12-16 Lytix Biopharma As Compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652551A (en) * 1984-06-22 1987-03-24 Abbott Laboratories Renin inhibiting compounds
DK34086A (en) * 1985-01-23 1986-07-24 Abbott Lab PEPTIDYLAMINODIOLS
IL81234A (en) * 1986-01-16 1992-09-06 Abbott Lab Peptidylaminodiols,process for their preparation and pharmaceutical compositions comprising them
US4792555A (en) * 1987-03-20 1988-12-20 American Home Products Corporation Phospholipase A2 inhibitors

Also Published As

Publication number Publication date
NO884434D0 (en) 1988-10-05
EP0310918A3 (en) 1990-12-12
MC1985A1 (en) 1989-11-23
HUT49322A (en) 1989-09-28
FI884598A0 (en) 1988-10-06
AU627156B2 (en) 1992-08-20
JPH02256658A (en) 1990-10-17
ZA887322B (en) 1989-06-28
AU2330788A (en) 1989-06-08
FI884598A (en) 1989-04-07
KR890006572A (en) 1989-06-14
EP0310918A2 (en) 1989-04-12
NZ226395A (en) 1991-12-23
YU185188A (en) 1990-12-31
DK523288A (en) 1989-04-07
PT88679A (en) 1989-07-31
NO884434L (en) 1989-04-07
DK523288D0 (en) 1988-09-20

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