IL85607A - High drug:lipid complexes and methods for their preparation - Google Patents

High drug:lipid complexes and methods for their preparation

Info

Publication number
IL85607A
IL85607A IL85607A IL8560788A IL85607A IL 85607 A IL85607 A IL 85607A IL 85607 A IL85607 A IL 85607A IL 8560788 A IL8560788 A IL 8560788A IL 85607 A IL85607 A IL 85607A
Authority
IL
Israel
Prior art keywords
lipid
lipid complexes
high drug
compositions
methods
Prior art date
Application number
IL85607A
Other languages
English (en)
Other versions
IL85607A0 (en
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27361805&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL85607(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of IL85607A0 publication Critical patent/IL85607A0/xx
Publication of IL85607A publication Critical patent/IL85607A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B2227/00—Photographic printing apparatus
    • G03B2227/32—Projection printing apparatus, e.g. enlarging apparatus, copying camera
    • G03B2227/325—Microcapsule copiers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Vehicle Step Arrangements And Article Storage (AREA)
  • Catalysts (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
IL85607A 1987-03-05 1988-03-02 High drug:lipid complexes and methods for their preparation IL85607A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2215787A 1987-03-05 1987-03-05
US6990887A 1987-07-06 1987-07-06
US7930987A 1987-07-29 1987-07-29

Publications (2)

Publication Number Publication Date
IL85607A0 IL85607A0 (en) 1988-08-31
IL85607A true IL85607A (en) 1992-08-18

Family

ID=27361805

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85607A IL85607A (en) 1987-03-05 1988-03-02 High drug:lipid complexes and methods for their preparation

Country Status (20)

Country Link
EP (1) EP0282405B2 (fr)
KR (1) KR970002870B1 (fr)
CN (1) CN1044093C (fr)
AT (1) ATE118169T1 (fr)
AU (1) AU622405B2 (fr)
CA (1) CA1338701C (fr)
DE (1) DE3852961T3 (fr)
DK (1) DK176010B1 (fr)
ES (1) ES2070131T5 (fr)
FI (1) FI102724B (fr)
GR (1) GR3015916T3 (fr)
HK (1) HK1007495A1 (fr)
IE (1) IE67152B1 (fr)
IL (1) IL85607A (fr)
LU (1) LU88684I2 (fr)
NL (1) NL990004I1 (fr)
NO (4) NO179995C (fr)
NZ (1) NZ223660A (fr)
PT (1) PT86913B (fr)
WO (1) WO1988006443A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
AU598958B2 (en) * 1987-11-12 1990-07-05 Vestar, Inc. Improved amphotericin b liposome preparation
DE69026820T2 (de) * 1989-03-31 1996-11-28 Univ California Zubereitung von liposomen- und lipid-komplexzusammensetzungen
US5188951A (en) * 1990-04-17 1993-02-23 The Liposome Company, Inc. Enzymatic synthesis of soluble phosphatides from phospholipids
DE4108902A1 (de) * 1990-08-06 1992-02-13 Nattermann A & Cie Wasserhaltiges liposomensystem
US5556637A (en) * 1990-08-06 1996-09-17 A. Nattermann & Cie. Gmbh Water containing liposome system
US5534502A (en) * 1990-11-06 1996-07-09 Nippon Shinyaku Co. Ltd. Process for producing fat emulsion
EP0556392A4 (fr) * 1990-11-06 1994-03-17 Nippon Shinyaku Co Ltd Procede de production d'une emulsion grasse.
WO1993003737A1 (fr) * 1991-08-14 1993-03-04 Liposome Technology, Inc. Procede de traitement contre le vih avec de l'amphotericine b a faible toxicite
ATE210966T1 (de) * 1993-05-21 2002-01-15 Liposome Co Inc Reduzierung von durch liposome induzierte physiologischen gegenreaktionen
US5716526A (en) * 1994-01-14 1998-02-10 The Liposome Company, Inc. Method of separating materials from liposomes or lipid complexes
US5902604A (en) * 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US6165997A (en) * 1997-11-20 2000-12-26 Statens Serum Institut Phospholipids having antimicrobial activity with or without the presence of antimicrobials
EP2007355A2 (fr) * 2005-12-08 2008-12-31 Wyeth a Corporation of the State of Delaware Compositions liposomales
KR101132626B1 (ko) * 2009-10-12 2012-04-02 주식회사 녹십자 난용성 약물의 전달을 위한 고밀도지단백 나노입자의 제조방법
AU2010359346B2 (en) 2010-08-20 2015-01-29 Dr. Reddy's Laboratories Sa Phospholipid depot
WO2012054447A2 (fr) 2010-10-22 2012-04-26 Dr. Reddy's Laboratories, Inc. Utilisation d'un dépôt visqueux de phospholipides stable pendant le stockage pour traiter les plaies
WO2013168167A1 (fr) 2012-05-10 2013-11-14 Painreform Ltd. Préparations de dépôt d'un principe actif hydrophobe et procédés de préparation associés
US10799456B2 (en) 2015-06-15 2020-10-13 University Of Washington Multiple drug lipid nanoparticle composition and related methods for extended drug levels in blood and lymph tissue

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310506A (en) * 1979-02-22 1982-01-12 California Institute Of Technology Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
US4604376A (en) * 1982-04-21 1986-08-05 Research Corporation Enteric compounds and complexes
US4436746A (en) * 1982-09-30 1984-03-13 Ciba-Geigy Corporation Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
IL78929A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
IL78930A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Lyophilized emulsion compositions for parenteral administration

Also Published As

Publication number Publication date
FI102724B1 (fi) 1999-02-15
IE880600L (en) 1988-09-05
AU1799088A (en) 1988-09-26
FI102724B (fi) 1999-02-15
IE67152B1 (en) 1996-03-06
NO179995C (no) 1997-01-29
NZ223660A (en) 1990-11-27
PT86913A (pt) 1989-03-30
CN88101864A (zh) 1988-09-28
NO179995B (no) 1996-10-21
AU622405B2 (en) 1992-04-09
DE3852961T2 (de) 1995-07-06
NO884391L (no) 1988-11-24
EP0282405B1 (fr) 1995-02-08
DK98089D0 (da) 1989-03-01
NO180147C (no) 1997-02-26
EP0282405B2 (fr) 1998-07-22
GR3015916T3 (en) 1995-07-31
DK98089A (da) 1989-03-01
HK1007495A1 (en) 1999-04-16
ATE118169T1 (de) 1995-02-15
DE3852961T3 (de) 1998-12-24
LU88684I2 (fr) 1996-04-29
IL85607A0 (en) 1988-08-31
CA1338701C (fr) 1996-11-12
KR970002870B1 (ko) 1997-03-12
FI894161A0 (fi) 1989-09-04
ES2070131T3 (es) 1995-06-01
KR890700341A (ko) 1989-04-24
NO884391D0 (no) 1988-10-04
DE3852961D1 (de) 1995-03-23
NO1998013I1 (no) 1998-03-25
ES2070131T5 (es) 1998-10-01
WO1988006443A1 (fr) 1988-09-07
DK176010B1 (da) 2005-11-28
NO944071L (no) 1988-11-24
EP0282405A3 (en) 1989-01-04
PT86913B (pt) 1993-07-30
EP0282405A2 (fr) 1988-09-14
CN1044093C (zh) 1999-07-14
NL990004I1 (nl) 1999-04-01
NO944071D0 (no) 1994-10-26
NO1998012I1 (no) 1998-03-25
NO180147B (no) 1996-11-18

Similar Documents

Publication Publication Date Title
IL85607A (en) High drug:lipid complexes and methods for their preparation
AU681452B2 (en) Pernasal composition and pernasal preparation containing thesame
DE3575927D1 (de) Purinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
CA2121345A1 (fr) Compositions de sels d'antibiotiques oligosaccharidiques lipophiles
EP0412554A3 (en) Sustained-release preparation for administration into brain
IL92797A0 (en) Therapeutical active substituted benzimidazole and process for its preparation
IE894050L (en) Compound with gastric acid inhibitory effect and process for¹its preparation
AU8687391A (en) Lithium treatment
DE3175733D1 (en) An orally administered drug form comprising a glycosidic antibiotic and an adjuvant
SE7708622L (sv) 2-bensyl-perhydroazepiner, sett for framstellning derav och lekemedel, innehallande dem
EP0335446A3 (fr) Agents de traitement des néoplasmes
AU1022688A (en) Antibacterial lyophilized preparation
Carbon Effectiveness of moxalactam in septicemias and focal infections. Results of the cooperative study carried out in France.
EP0281092A3 (fr) Dérivés de céphalosporine et procédé pour leur préparation
Dellamonica et al. Evaluation of rifampicin combined with a synergic antibiotic in severe staphylococcal infection. Report of selection of resistant mutants in seven cases.
CA2080040A1 (fr) Methodes de prevention d'infections mycobacteriennes par administration de rifabutine
IT1251993B (it) Composizioni farmaceutiche ad uso orale,a base di esteri di gangliosidi,per il trattamento di neuropatie del sistema nervoso periferico

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
EXP Patent expired