IL85154A - Process for the synthesis of vinblastine and vincristine and related dimer alkaloid compounds - Google Patents
Process for the synthesis of vinblastine and vincristine and related dimer alkaloid compoundsInfo
- Publication number
- IL85154A IL85154A IL85154A IL8515488A IL85154A IL 85154 A IL85154 A IL 85154A IL 85154 A IL85154 A IL 85154A IL 8515488 A IL8515488 A IL 8515488A IL 85154 A IL85154 A IL 85154A
- Authority
- IL
- Israel
- Prior art keywords
- vinblastine
- vincristine
- synthesis
- alkaloid compounds
- related dimer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL8734788A IL87347A (en) | 1987-08-06 | 1988-08-04 | Process for the synthesis of vinblastine and vincristine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA000527897A CA1341261C (en) | 1987-01-22 | 1987-01-22 | Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine |
Publications (2)
Publication Number | Publication Date |
---|---|
IL85154A0 IL85154A0 (en) | 1988-06-30 |
IL85154A true IL85154A (en) | 1992-08-18 |
Family
ID=4134803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL85154A IL85154A (en) | 1987-01-22 | 1988-01-21 | Process for the synthesis of vinblastine and vincristine and related dimer alkaloid compounds |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPH0613531B2 (de) |
CA (1) | CA1341261C (de) |
CH (1) | CH675724A5 (de) |
DE (1) | DE3801450C2 (de) |
FR (1) | FR2611202A1 (de) |
GB (1) | GB2204036B (de) |
IL (1) | IL85154A (de) |
IT (1) | IT1215751B (de) |
NL (1) | NL8800134A (de) |
SE (1) | SE467874B (de) |
ZA (1) | ZA88408B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1341262C (en) * | 1987-08-06 | 2001-06-26 | Camille A. Boulet | A new process of the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine |
US5047528A (en) * | 1987-01-22 | 1991-09-10 | University Of Bristish Columbia | Process of synthesis of vinblastine and vincristine |
USRE37449E1 (en) | 1987-02-06 | 2001-11-13 | University Of British Columbia | Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine |
US5037977A (en) * | 1988-08-11 | 1991-08-06 | Mitsui Petrochemical Industries Ltd. | Method for production of dimeric alkaloids |
HU209687B (en) * | 1989-03-04 | 1994-10-28 | Mitsui Petrochemical Ind | Process for producing bisz-indole-alkaloids |
US5432279A (en) * | 1989-03-04 | 1995-07-11 | Mitsui Petrochemical Industries, Inc. | Process for the preparation of binary indole alkaloids |
FR2779146B1 (fr) * | 1998-06-02 | 2002-01-18 | Roowin | Nouveaux derives de vinca-alcaloides et procedes de preparation |
CN103936769B (zh) * | 2014-04-30 | 2016-10-05 | 淮海工学院 | 一种制备高光学纯脱水长春碱的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2296418B1 (de) * | 1974-12-30 | 1978-07-21 | Anvar | |
US4279817A (en) * | 1975-05-30 | 1981-07-21 | The United States Of America As Represented By The Department Of Health & Human Services | Method for producing dimer alkaloids |
GB1551054A (en) * | 1976-03-04 | 1979-08-22 | Atta Ur Rahman | Syntheses of vinblastine vincristine and vinrosidine |
FR2358412A1 (fr) * | 1976-07-13 | 1978-02-10 | Parcor | Procede de preparation de la vincamine et d'alcaloides apparentes |
-
1987
- 1987-01-22 CA CA000527897A patent/CA1341261C/en not_active Expired - Fee Related
-
1988
- 1988-01-20 DE DE3801450A patent/DE3801450C2/de not_active Expired - Fee Related
- 1988-01-20 SE SE8800170A patent/SE467874B/sv not_active IP Right Cessation
- 1988-01-21 GB GB8801296A patent/GB2204036B/en not_active Expired - Lifetime
- 1988-01-21 ZA ZA88408A patent/ZA88408B/xx unknown
- 1988-01-21 NL NL8800134A patent/NL8800134A/nl not_active Application Discontinuation
- 1988-01-21 IT IT8819156A patent/IT1215751B/it active
- 1988-01-21 IL IL85154A patent/IL85154A/xx not_active IP Right Cessation
- 1988-01-21 CH CH206/88A patent/CH675724A5/de not_active IP Right Cessation
- 1988-01-21 FR FR8800650A patent/FR2611202A1/fr active Granted
- 1988-01-22 JP JP63013473A patent/JPH0613531B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA1341261C (en) | 2001-06-26 |
ZA88408B (en) | 1989-04-26 |
DE3801450A1 (de) | 1988-08-18 |
JPH01131187A (ja) | 1989-05-24 |
GB2204036A (en) | 1988-11-02 |
CH675724A5 (de) | 1990-10-31 |
SE8800170L (sv) | 1988-07-23 |
IL85154A0 (en) | 1988-06-30 |
JPH0613531B2 (ja) | 1994-02-23 |
DE3801450C2 (de) | 1999-02-25 |
IT8819156A0 (it) | 1988-01-21 |
IT1215751B (it) | 1990-02-22 |
SE8800170D0 (sv) | 1988-01-20 |
FR2611202A1 (fr) | 1988-08-26 |
GB2204036B (en) | 1991-03-27 |
FR2611202B1 (de) | 1994-08-19 |
SE467874B (sv) | 1992-09-28 |
NL8800134A (nl) | 1988-08-16 |
GB8801296D0 (en) | 1988-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |