IL85145A - Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity - Google Patents

Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity

Info

Publication number
IL85145A
IL85145A IL8514588A IL8514588A IL85145A IL 85145 A IL85145 A IL 85145A IL 8514588 A IL8514588 A IL 8514588A IL 8514588 A IL8514588 A IL 8514588A IL 85145 A IL85145 A IL 85145A
Authority
IL
Israel
Prior art keywords
heparin
cells
activity
metastatic
anticoagulant activity
Prior art date
Application number
IL8514588A
Other languages
English (en)
Hebrew (he)
Original Assignee
Univ Australian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Australian filed Critical Univ Australian
Priority to IL10635488A priority Critical patent/IL106354A/en
Priority to IL106354A priority patent/IL106354A0/xx
Publication of IL85145A publication Critical patent/IL85145A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL8514588A 1987-01-23 1988-01-20 Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity IL85145A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL10635488A IL106354A (en) 1987-01-23 1988-01-20 Pharmaceuticals or veterinary preparations containing fucoid or heparin modified for anti-inflammatory treatment
IL106354A IL106354A0 (en) 1987-01-23 1993-07-15 Pharmaceutical or veterinary compositions containing a sulfated polysaccharide for anti-inflammatory treatment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPH999187 1987-01-23

Publications (1)

Publication Number Publication Date
IL85145A true IL85145A (en) 1994-08-26

Family

ID=3771996

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8514588A IL85145A (en) 1987-01-23 1988-01-20 Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity

Country Status (9)

Country Link
EP (2) EP0355088B1 (de)
JP (2) JP2701904B2 (de)
AT (2) ATE160941T1 (de)
CA (1) CA1316828C (de)
DE (2) DE3856321T2 (de)
HK (1) HK1014153A1 (de)
IL (1) IL85145A (de)
SG (2) SG52246A1 (de)
WO (1) WO1988005301A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88554A0 (en) * 1988-12-01 1989-07-31 Hadassah Med Org Compositions containing a compound binding to a heparin receptor
KR100235782B1 (ko) * 1991-05-02 1999-12-15 파울리나 벤-아미 병리학적 과정의 예방 또는 치료를 위한 성분물
US6750207B1 (en) 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
US5861382A (en) * 1992-05-01 1999-01-19 Yeda Research And Development Co. Ltd. Methods for regulation of active TNF-α
IT1264709B1 (it) * 1993-07-12 1996-10-04 Italfarmaco Spa Derivati eparinici ad attivita' antimetastatica
JP3403496B2 (ja) * 1993-09-24 2003-05-06 株式会社ヤクルト本社 抗潰瘍剤およびヘリコバクター・ピロリの定着阻害剤
AU700451B2 (en) * 1993-10-07 1999-01-07 Glycomed Incorporated Highly sulfated maltooligosaccharides with heparin-like properties
US5739115A (en) * 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties
US5783568A (en) * 1994-06-10 1998-07-21 Sugen, Inc. Methods for treating cancer and other cell proliferative diseases
CA2233343A1 (en) 1995-09-29 1997-04-03 Ibex Technologies Inc. Use of heparinases to decrease inflammatory responses
JP2000507204A (ja) * 1995-12-18 2000-06-13 ステイヒテイング・サンキン・ブロードボールジーニング C1―インヒビターの補体及び血液凝固阻害特性の強化
CA2243543A1 (en) * 1996-01-26 1997-07-31 Research Institute For Glycotechnology Apoptosis inducers
CA2253573C (en) * 1996-06-12 2005-12-06 Takara Shuzo Co., Ltd. Fucoidan-containing foods or beverages
US7151099B2 (en) 1998-07-31 2006-12-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases
US8304390B2 (en) 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US7345039B2 (en) 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
AU6593400A (en) * 1999-08-20 2001-03-19 Takara Shuzo Co., Ltd. Remedies
US6641571B2 (en) 2000-01-05 2003-11-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery
WO2002083700A2 (en) * 2001-04-16 2002-10-24 Ivax Research, Inc. Hypersulfated disaccharides and methods of using the same for the treatment of inflammations
EP2343077B1 (de) 2001-09-12 2013-07-17 SIGMA-TAU Research Switzerland S.A. Derivate von total N-desulfatierten Glycosaminoglycanen als Inhibitoren von Heparanase, mit antiangiogener Wirkung und ohne antikoagulatorische Wirkung
US7285536B2 (en) 2001-12-05 2007-10-23 Yeda Research And Development Co., Ltd. Anti-cancer therapeutic compounds
ITMI20021294A1 (it) * 2002-06-12 2003-12-12 Inalco Spa Polisaccaridi batterici o-solfatati e loro uso
WO2005059563A2 (en) 2003-12-18 2005-06-30 Procognia Ltd. Method for analyzing a glycomolecule
RU2347574C2 (ru) * 2004-05-27 2009-02-27 Эвиджен, Инк. Способы лечения коагулопатий с использованием сульфатированных полисахаридов
JP5701498B2 (ja) * 2009-12-01 2015-04-15 公益財団法人微生物化学研究会 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物
JP5934735B2 (ja) * 2014-03-28 2016-06-15 株式会社オプトクリエーション ナノバブル・フコイダン水素水
NL2024493B1 (en) * 2019-12-16 2021-09-02 Logick Energetics B V Pharmaceutical composition for preventing or stopping metastases
US20230023285A1 (en) 2019-12-18 2023-01-26 Logick Energetics B.V. Pharmaceutical composition for use in preventing or stopping metastases
WO2022265510A1 (en) * 2021-06-17 2022-12-22 Logick Energetics B.V. Pharmaceutical composition for use in the treatment of metastatic epithelial ovarian cancer, metastatic fallopian tube carcinoma or metastatic primary peritoneal carcinoma

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1730M (fr) * 1962-01-17 1963-03-18 Charles Riviere Nouvelle composition de collyre.
JPS5943929B2 (ja) * 1979-08-13 1984-10-25 サッポロビール株式会社 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤
CA1226816A (en) * 1982-12-20 1987-09-15 Moses J. Folkman Inhibition of angiogenesis
AU555747B2 (en) * 1983-08-09 1986-10-09 Cilco Inc. Chondroitin sulfate and sodium hyaluronate composition
FR2553287B1 (fr) * 1983-10-18 1986-09-12 Choay Sa Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire
DE3422518A1 (de) * 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
US4710493A (en) * 1984-08-14 1987-12-01 Albert Landsberger Therapeutic agent for the use in cancer treatment
FR2584606A1 (fr) * 1985-07-12 1987-01-16 Dropic Utilisation de poly- et oligosaccharides pour l'obtention de medicaments actifs dans les pathologies du tissu conjonctif
IL79255A0 (en) * 1986-06-26 1986-09-30 Hadassah Med Org Composition for metastasis prevention
IL79254A0 (en) * 1986-06-26 1986-09-30 Hadassah Med Org Compositions for preventing graft rejection
JP2511829B2 (ja) * 1987-03-19 1996-07-03 アースロファーム ピーティーワイ.リミティッド 抗炎症作用のある化合物および組成物
JPH06157520A (ja) * 1992-11-13 1994-06-03 Kirin Brewery Co Ltd 新規物質hq24

Also Published As

Publication number Publication date
EP0355088A4 (de) 1990-06-26
JPH09328431A (ja) 1997-12-22
DE3856083D1 (de) 1998-01-22
JPH02502006A (ja) 1990-07-05
DE3856321D1 (de) 1999-05-06
SG52246A1 (en) 1998-09-28
EP0631784A1 (de) 1995-01-04
SG45156A1 (en) 1998-01-16
EP0355088B1 (de) 1997-12-10
DE3856083T2 (de) 1998-07-02
ATE160941T1 (de) 1997-12-15
DE3856321T2 (de) 1999-08-26
EP0631784B1 (de) 1999-03-31
EP0355088A1 (de) 1990-02-28
WO1988005301A1 (en) 1988-07-28
ATE178212T1 (de) 1999-04-15
JP2701904B2 (ja) 1998-01-21
CA1316828C (en) 1993-04-27
HK1014153A1 (en) 1999-09-24
JP2752353B2 (ja) 1998-05-18

Similar Documents

Publication Publication Date Title
IL85145A (en) Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
US5541166A (en) Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity
Coombe et al. Analysis of the inhibition of tumour metastasis by sulphated polysaccharides
Laurent et al. Hyaluronan 1
Willenborg et al. Inhibition of allergic encephalomyelitis in rats by treatment with sulfated polysaccharides.
AU668865B2 (en) Compositions for the prevention and/or treatment of pathological processes
JPH06506685A (ja) 新規な非抗凝固剤ヘパリン誘導体
US4687765A (en) Method and composition for thrombolytic treatment
AU2003214422B2 (en) Glycodendrimers having biological activity
US8524688B2 (en) Use of sulfated glycosaminoglycans for establishing effective labor in women
JPH06506248A (ja) 新規な非抗凝固剤ヘパリン誘導体
US20080214480A1 (en) Method for Treating Sickle Cell Disease and Sickle Cell Disease Sequalae
WO2013095215A1 (en) Low anticoagulant heparins
Dziarski Enhancement of mixed leukocyte reaction and cytotoxic antitumor responses by heparin.
AU605839B2 (en) Compounds having anti-metastatic and/or anti-inflammatory activity
AU605839C (en) Compounds having anti-metastatic and/or anti-inflammatory activity
IL106354A (en) Pharmaceuticals or veterinary preparations containing fucoid or heparin modified for anti-inflammatory treatment
JP2004507562A (ja) 抗血栓性組成物
KR19980702520A (ko) 스트렙토코커스 아갈락티아에 Ia형 또는 Ib형 표면 다당을 주성분으로 하는 암 전이 저해제
JP2004002239A (ja) TNF−α産生抑制剤
KR20010104329A (ko) 기관보호 용액
AU2796900A (en) Organoprotective solutions

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees