IL85145A - Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity - Google Patents
Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activityInfo
- Publication number
- IL85145A IL85145A IL8514588A IL8514588A IL85145A IL 85145 A IL85145 A IL 85145A IL 8514588 A IL8514588 A IL 8514588A IL 8514588 A IL8514588 A IL 8514588A IL 85145 A IL85145 A IL 85145A
- Authority
- IL
- Israel
- Prior art keywords
- heparin
- cells
- activity
- metastatic
- anticoagulant activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Detergent Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL10635488A IL106354A (en) | 1987-01-23 | 1988-01-20 | Pharmaceuticals or veterinary preparations containing fucoid or heparin modified for anti-inflammatory treatment |
IL106354A IL106354A0 (en) | 1987-01-23 | 1993-07-15 | Pharmaceutical or veterinary compositions containing a sulfated polysaccharide for anti-inflammatory treatment |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPH999187 | 1987-01-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL85145A true IL85145A (en) | 1994-08-26 |
Family
ID=3771996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL8514588A IL85145A (en) | 1987-01-23 | 1988-01-20 | Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0355088B1 (de) |
JP (2) | JP2701904B2 (de) |
AT (2) | ATE160941T1 (de) |
CA (1) | CA1316828C (de) |
DE (2) | DE3856321T2 (de) |
HK (1) | HK1014153A1 (de) |
IL (1) | IL85145A (de) |
SG (2) | SG52246A1 (de) |
WO (1) | WO1988005301A1 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL88554A0 (en) * | 1988-12-01 | 1989-07-31 | Hadassah Med Org | Compositions containing a compound binding to a heparin receptor |
KR100235782B1 (ko) * | 1991-05-02 | 1999-12-15 | 파울리나 벤-아미 | 병리학적 과정의 예방 또는 치료를 위한 성분물 |
US6750207B1 (en) | 1992-05-01 | 2004-06-15 | Yeda Research And Development Co. Ltd. | Compositions for the regulation of cytokine activity |
US5861382A (en) * | 1992-05-01 | 1999-01-19 | Yeda Research And Development Co. Ltd. | Methods for regulation of active TNF-α |
IT1264709B1 (it) * | 1993-07-12 | 1996-10-04 | Italfarmaco Spa | Derivati eparinici ad attivita' antimetastatica |
JP3403496B2 (ja) * | 1993-09-24 | 2003-05-06 | 株式会社ヤクルト本社 | 抗潰瘍剤およびヘリコバクター・ピロリの定着阻害剤 |
AU700451B2 (en) * | 1993-10-07 | 1999-01-07 | Glycomed Incorporated | Highly sulfated maltooligosaccharides with heparin-like properties |
US5739115A (en) * | 1993-10-07 | 1998-04-14 | Glycomed Incorporated | Sulfated maltooligosaccharides with heparin-like properties |
US5783568A (en) * | 1994-06-10 | 1998-07-21 | Sugen, Inc. | Methods for treating cancer and other cell proliferative diseases |
CA2233343A1 (en) | 1995-09-29 | 1997-04-03 | Ibex Technologies Inc. | Use of heparinases to decrease inflammatory responses |
JP2000507204A (ja) * | 1995-12-18 | 2000-06-13 | ステイヒテイング・サンキン・ブロードボールジーニング | C1―インヒビターの補体及び血液凝固阻害特性の強化 |
CA2243543A1 (en) * | 1996-01-26 | 1997-07-31 | Research Institute For Glycotechnology | Apoptosis inducers |
CA2253573C (en) * | 1996-06-12 | 2005-12-06 | Takara Shuzo Co., Ltd. | Fucoidan-containing foods or beverages |
US7151099B2 (en) | 1998-07-31 | 2006-12-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases |
US8304390B2 (en) | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
US7892530B2 (en) | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
US7345039B2 (en) | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
AU6593400A (en) * | 1999-08-20 | 2001-03-19 | Takara Shuzo Co., Ltd. | Remedies |
US6641571B2 (en) | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
WO2002083700A2 (en) * | 2001-04-16 | 2002-10-24 | Ivax Research, Inc. | Hypersulfated disaccharides and methods of using the same for the treatment of inflammations |
EP2343077B1 (de) | 2001-09-12 | 2013-07-17 | SIGMA-TAU Research Switzerland S.A. | Derivate von total N-desulfatierten Glycosaminoglycanen als Inhibitoren von Heparanase, mit antiangiogener Wirkung und ohne antikoagulatorische Wirkung |
US7285536B2 (en) | 2001-12-05 | 2007-10-23 | Yeda Research And Development Co., Ltd. | Anti-cancer therapeutic compounds |
ITMI20021294A1 (it) * | 2002-06-12 | 2003-12-12 | Inalco Spa | Polisaccaridi batterici o-solfatati e loro uso |
WO2005059563A2 (en) | 2003-12-18 | 2005-06-30 | Procognia Ltd. | Method for analyzing a glycomolecule |
RU2347574C2 (ru) * | 2004-05-27 | 2009-02-27 | Эвиджен, Инк. | Способы лечения коагулопатий с использованием сульфатированных полисахаридов |
JP5701498B2 (ja) * | 2009-12-01 | 2015-04-15 | 公益財団法人微生物化学研究会 | 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物 |
JP5934735B2 (ja) * | 2014-03-28 | 2016-06-15 | 株式会社オプトクリエーション | ナノバブル・フコイダン水素水 |
NL2024493B1 (en) * | 2019-12-16 | 2021-09-02 | Logick Energetics B V | Pharmaceutical composition for preventing or stopping metastases |
US20230023285A1 (en) | 2019-12-18 | 2023-01-26 | Logick Energetics B.V. | Pharmaceutical composition for use in preventing or stopping metastases |
WO2022265510A1 (en) * | 2021-06-17 | 2022-12-22 | Logick Energetics B.V. | Pharmaceutical composition for use in the treatment of metastatic epithelial ovarian cancer, metastatic fallopian tube carcinoma or metastatic primary peritoneal carcinoma |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1730M (fr) * | 1962-01-17 | 1963-03-18 | Charles Riviere | Nouvelle composition de collyre. |
JPS5943929B2 (ja) * | 1979-08-13 | 1984-10-25 | サッポロビール株式会社 | 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤 |
CA1226816A (en) * | 1982-12-20 | 1987-09-15 | Moses J. Folkman | Inhibition of angiogenesis |
AU555747B2 (en) * | 1983-08-09 | 1986-10-09 | Cilco Inc. | Chondroitin sulfate and sodium hyaluronate composition |
FR2553287B1 (fr) * | 1983-10-18 | 1986-09-12 | Choay Sa | Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire |
DE3422518A1 (de) * | 1984-06-16 | 1985-12-19 | B. Braun Melsungen Ag, 3508 Melsungen | Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen |
US4710493A (en) * | 1984-08-14 | 1987-12-01 | Albert Landsberger | Therapeutic agent for the use in cancer treatment |
FR2584606A1 (fr) * | 1985-07-12 | 1987-01-16 | Dropic | Utilisation de poly- et oligosaccharides pour l'obtention de medicaments actifs dans les pathologies du tissu conjonctif |
IL79255A0 (en) * | 1986-06-26 | 1986-09-30 | Hadassah Med Org | Composition for metastasis prevention |
IL79254A0 (en) * | 1986-06-26 | 1986-09-30 | Hadassah Med Org | Compositions for preventing graft rejection |
JP2511829B2 (ja) * | 1987-03-19 | 1996-07-03 | アースロファーム ピーティーワイ.リミティッド | 抗炎症作用のある化合物および組成物 |
JPH06157520A (ja) * | 1992-11-13 | 1994-06-03 | Kirin Brewery Co Ltd | 新規物質hq24 |
-
1988
- 1988-01-20 IL IL8514588A patent/IL85145A/en not_active IP Right Cessation
- 1988-01-21 CA CA000557015A patent/CA1316828C/en not_active Expired - Fee Related
- 1988-01-22 AT AT88901519T patent/ATE160941T1/de not_active IP Right Cessation
- 1988-01-22 WO PCT/AU1988/000017 patent/WO1988005301A1/en active IP Right Grant
- 1988-01-22 SG SG1996001249A patent/SG52246A1/en unknown
- 1988-01-22 EP EP88901519A patent/EP0355088B1/de not_active Expired - Lifetime
- 1988-01-22 EP EP94103441A patent/EP0631784B1/de not_active Expired - Lifetime
- 1988-01-22 DE DE3856321T patent/DE3856321T2/de not_active Expired - Fee Related
- 1988-01-22 JP JP63501413A patent/JP2701904B2/ja not_active Expired - Lifetime
- 1988-01-22 SG SG1996000766A patent/SG45156A1/en unknown
- 1988-01-22 AT AT94103441T patent/ATE178212T1/de not_active IP Right Cessation
- 1988-01-22 DE DE3856083T patent/DE3856083T2/de not_active Expired - Fee Related
-
1997
- 1997-03-03 JP JP9047706A patent/JP2752353B2/ja not_active Expired - Lifetime
-
1998
- 1998-12-24 HK HK98115448A patent/HK1014153A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0355088A4 (de) | 1990-06-26 |
JPH09328431A (ja) | 1997-12-22 |
DE3856083D1 (de) | 1998-01-22 |
JPH02502006A (ja) | 1990-07-05 |
DE3856321D1 (de) | 1999-05-06 |
SG52246A1 (en) | 1998-09-28 |
EP0631784A1 (de) | 1995-01-04 |
SG45156A1 (en) | 1998-01-16 |
EP0355088B1 (de) | 1997-12-10 |
DE3856083T2 (de) | 1998-07-02 |
ATE160941T1 (de) | 1997-12-15 |
DE3856321T2 (de) | 1999-08-26 |
EP0631784B1 (de) | 1999-03-31 |
EP0355088A1 (de) | 1990-02-28 |
WO1988005301A1 (en) | 1988-07-28 |
ATE178212T1 (de) | 1999-04-15 |
JP2701904B2 (ja) | 1998-01-21 |
CA1316828C (en) | 1993-04-27 |
HK1014153A1 (en) | 1999-09-24 |
JP2752353B2 (ja) | 1998-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |