PL1748781T3 - Sposoby do leczenia zaburzeń związanych z krwawieniem z zastosowaniem siarczanowanych polisacharydów - Google Patents

Sposoby do leczenia zaburzeń związanych z krwawieniem z zastosowaniem siarczanowanych polisacharydów

Info

Publication number
PL1748781T3
PL1748781T3 PL05765950T PL05765950T PL1748781T3 PL 1748781 T3 PL1748781 T3 PL 1748781T3 PL 05765950 T PL05765950 T PL 05765950T PL 05765950 T PL05765950 T PL 05765950T PL 1748781 T3 PL1748781 T3 PL 1748781T3
Authority
PL
Poland
Prior art keywords
methods
sulfated polysaccharides
bleeding disorders
treating bleeding
treating
Prior art date
Application number
PL05765950T
Other languages
English (en)
Inventor
Kirk W Johnson
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Publication of PL1748781T3 publication Critical patent/PL1748781T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/731—Carrageenans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL05765950T 2004-05-27 2005-05-27 Sposoby do leczenia zaburzeń związanych z krwawieniem z zastosowaniem siarczanowanych polisacharydów PL1748781T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57484504P 2004-05-27 2004-05-27
EP05765950A EP1748781B1 (en) 2004-05-27 2005-05-27 Methods for treating bleeding disorders using sulfated polysaccharides
PCT/US2005/018669 WO2005117912A1 (en) 2004-05-27 2005-05-27 Methods for treating bleeding disorders using sulfated polysaccharides

Publications (1)

Publication Number Publication Date
PL1748781T3 true PL1748781T3 (pl) 2013-05-31

Family

ID=35462725

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05765950T PL1748781T3 (pl) 2004-05-27 2005-05-27 Sposoby do leczenia zaburzeń związanych z krwawieniem z zastosowaniem siarczanowanych polisacharydów

Country Status (15)

Country Link
US (4) US7767654B2 (pl)
EP (2) EP1748781B1 (pl)
JP (2) JP5232470B2 (pl)
CN (2) CN1984664B (pl)
AU (1) AU2005249465B2 (pl)
BR (1) BRPI0511603A (pl)
CA (1) CA2567495C (pl)
CY (1) CY1113705T1 (pl)
DK (1) DK1748781T3 (pl)
ES (2) ES2399277T3 (pl)
PL (1) PL1748781T3 (pl)
PT (1) PT1748781E (pl)
RU (1) RU2347574C2 (pl)
SI (1) SI1748781T1 (pl)
WO (1) WO2005117912A1 (pl)

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GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
PL1748781T3 (pl) * 2004-05-27 2013-05-31 Baxter Int Sposoby do leczenia zaburzeń związanych z krwawieniem z zastosowaniem siarczanowanych polisacharydów
CA2648533A1 (en) * 2006-04-27 2007-11-08 Avigen, Inc. Method for treating thrombotic disorders using sulfated polysaccharides
EP2532686B1 (en) 2007-02-23 2018-05-16 Baxalta GmbH Process methods for fucoidan purification from seaweed extracts
US9956272B2 (en) * 2007-05-30 2018-05-01 Bio Products Laboratory Limited Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same
US20100297257A1 (en) 2007-11-09 2010-11-25 National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs) Anticoagulant antagonist and hemophillia procoagulant
AU2009284393B2 (en) * 2008-08-22 2014-09-25 Takeda Pharmaceutical Company Limited Methods for treating bleeding disorders
JP5746041B2 (ja) * 2008-12-11 2015-07-08 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ フィブリノーゲンと硫酸化多糖類に基づく製剤
CA2747721C (en) * 2008-12-19 2021-07-20 Baxter International Inc. Tfpi inhibitors and methods of use
US8632991B2 (en) * 2010-01-14 2014-01-21 Baxter International Inc. Methods and compositions for treating bleeding disorders
EP2547355B1 (en) 2010-03-19 2017-01-11 Baxalta GmbH Tfpi inhibitors and methods of use
CN103003422B (zh) * 2010-04-20 2015-02-11 奥克塔法马股份有限公司 用于药物蛋白的新型稳定剂
MX343784B (es) 2010-10-06 2016-11-23 Medimmune Ltd Factor ii y fibrinogeno para tratamiento de trastornos hemostaticos.
EP3417865A1 (en) 2011-07-19 2018-12-26 Baxalta GmbH Resorption enhancers as additives to improve the oral formulation of non-anticoagulant sulfated polysaccharides
EP2809326B1 (en) 2012-01-30 2018-07-25 Baxalta GmbH Non-anticoagulant sulfated or sulfonated polysaccharides
ES2744595T3 (es) 2012-01-30 2020-02-25 Baxalta GmbH Polímeros sintéticos sulfatados o sulfonados no anticoagulantes
EP2827883B1 (en) 2012-03-21 2019-05-08 Baxalta GmbH Tfpi inhibitors and methods of use
RU2472495C1 (ru) * 2012-05-05 2013-01-20 Илья Николаевич Медведев Способ нормализации уровня альфа2-антиплазмина у свиноматок с бронхитом
EP2662083A1 (en) 2012-05-08 2013-11-13 CSL Behring GmbH Sugar compositions for treating hemophilia a and/or von willebrand disease
US9417251B2 (en) 2012-08-14 2016-08-16 Baxalta GmbH Methods and systems for screening compositions comprising non-anticoagulant sulfated polysaccharides
CN103610684B (zh) * 2013-11-07 2016-04-06 苏州大学 糖类在制备治疗血小板数量相关疾病的药物中的应用
EP3677587A4 (en) * 2016-08-31 2021-04-14 Oji Holdings Corporation XYLOOLIGOSACCHARIDE ACID, AND METHOD FOR MANUFACTURING THE SAME
JP6225321B1 (ja) * 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
JP6281659B1 (ja) 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
CA3065747C (en) 2017-05-31 2024-10-01 Oji Holdings Corporation MOISTURIZING COMPOSITION CONTAINING PENTOSANNE POLYSULFATE
AU2018333249B2 (en) 2017-09-12 2023-03-02 Oji Holdings Corporation Pentosan polysulfate and method for producing pentosan polysulfate
WO2019124363A1 (ja) 2017-12-20 2019-06-27 王子ホールディングス株式会社 ポリ硫酸ペントサン及びポリ硫酸ペントサンを含む医薬
CN108822231A (zh) * 2018-06-29 2018-11-16 桂林理工大学 一种具有提高抗氧化活性的果胶多糖硫酸化修饰产物及其制备方法
SE1950885A1 (en) * 2019-07-11 2021-01-12 Faelker Knut Treatment of patients under antiplatelet medication experiencing acute bleeding complications during/after surgery

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PL1748781T3 (pl) * 2004-05-27 2013-05-31 Baxter Int Sposoby do leczenia zaburzeń związanych z krwawieniem z zastosowaniem siarczanowanych polisacharydów
CA2648533A1 (en) * 2006-04-27 2007-11-08 Avigen, Inc. Method for treating thrombotic disorders using sulfated polysaccharides

Also Published As

Publication number Publication date
AU2005249465A1 (en) 2005-12-15
DK1748781T3 (da) 2013-02-11
US20090269325A1 (en) 2009-10-29
US20120129777A1 (en) 2012-05-24
EP1748781A4 (en) 2008-07-02
EP2165711A1 (en) 2010-03-24
SI1748781T1 (sl) 2013-03-29
CN103251647A (zh) 2013-08-21
WO2005117912A1 (en) 2005-12-15
HK1103624A1 (en) 2007-12-28
US8771973B2 (en) 2014-07-08
JP2012046551A (ja) 2012-03-08
CN1984664A (zh) 2007-06-20
PT1748781E (pt) 2013-01-22
HK1142276A1 (en) 2010-12-03
JP2008500367A (ja) 2008-01-10
RU2347574C2 (ru) 2009-02-27
AU2005249465B2 (en) 2007-12-06
BRPI0511603A (pt) 2008-01-02
ES2399277T3 (es) 2013-03-27
CA2567495A1 (en) 2005-12-15
RU2006146801A (ru) 2008-07-10
JP5232470B2 (ja) 2013-07-10
US7829549B2 (en) 2010-11-09
US20110237512A1 (en) 2011-09-29
EP1748781B1 (en) 2012-12-19
EP1748781A1 (en) 2007-02-07
US8859526B2 (en) 2014-10-14
CY1113705T1 (el) 2016-06-22
ES2482105T3 (es) 2014-08-01
US20050282771A1 (en) 2005-12-22
EP2165711B1 (en) 2014-05-21
CA2567495C (en) 2014-02-18
CN1984664B (zh) 2013-07-24
US7767654B2 (en) 2010-08-03

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