DE3856083D1 - Sulfatierte polysaccharide mit antimetastasenwirkung - Google Patents

Sulfatierte polysaccharide mit antimetastasenwirkung

Info

Publication number
DE3856083D1
DE3856083D1 DE3856083T DE3856083T DE3856083D1 DE 3856083 D1 DE3856083 D1 DE 3856083D1 DE 3856083 T DE3856083 T DE 3856083T DE 3856083 T DE3856083 T DE 3856083T DE 3856083 D1 DE3856083 D1 DE 3856083D1
Authority
DE
Germany
Prior art keywords
antimetase
effect
sulfated polysaccharides
sulphate
heparin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3856083T
Other languages
English (en)
Other versions
DE3856083T2 (de
Inventor
Christopher Parish
John Snowden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Australian National University
Original Assignee
Australian National University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Australian National University filed Critical Australian National University
Application granted granted Critical
Publication of DE3856083D1 publication Critical patent/DE3856083D1/de
Publication of DE3856083T2 publication Critical patent/DE3856083T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3856083T 1987-01-23 1988-01-22 Sulfatierte polysaccharide mit antimetastasenwirkung Expired - Fee Related DE3856083T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPH999187 1987-01-23
PCT/AU1988/000017 WO1988005301A1 (en) 1987-01-23 1988-01-22 Sulphated polysaccharides having anti-metastatatic and/or anti-inflammatory activity

Publications (2)

Publication Number Publication Date
DE3856083D1 true DE3856083D1 (de) 1998-01-22
DE3856083T2 DE3856083T2 (de) 1998-07-02

Family

ID=3771996

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3856321T Expired - Fee Related DE3856321T2 (de) 1987-01-23 1988-01-22 Sulfatierte Polysaccharide mit antiinflammatorischer Aktivität
DE3856083T Expired - Fee Related DE3856083T2 (de) 1987-01-23 1988-01-22 Sulfatierte polysaccharide mit antimetastasenwirkung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3856321T Expired - Fee Related DE3856321T2 (de) 1987-01-23 1988-01-22 Sulfatierte Polysaccharide mit antiinflammatorischer Aktivität

Country Status (9)

Country Link
EP (2) EP0355088B1 (de)
JP (2) JP2701904B2 (de)
AT (2) ATE178212T1 (de)
CA (1) CA1316828C (de)
DE (2) DE3856321T2 (de)
HK (1) HK1014153A1 (de)
IL (1) IL85145A (de)
SG (2) SG52246A1 (de)
WO (1) WO1988005301A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88554A0 (en) * 1988-12-01 1989-07-31 Hadassah Med Org Compositions containing a compound binding to a heparin receptor
DE69232615T2 (de) * 1991-05-02 2003-01-30 Yeda Res & Dev Zusammensetzungen zur verhütung und/oder behandlung von pathologischen prozessen
US5861382A (en) * 1992-05-01 1999-01-19 Yeda Research And Development Co. Ltd. Methods for regulation of active TNF-α
US6750207B1 (en) 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
IT1264709B1 (it) * 1993-07-12 1996-10-04 Italfarmaco Spa Derivati eparinici ad attivita' antimetastatica
JP3403496B2 (ja) * 1993-09-24 2003-05-06 株式会社ヤクルト本社 抗潰瘍剤およびヘリコバクター・ピロリの定着阻害剤
CA2171465A1 (en) * 1993-10-07 1995-04-13 Peter Fugedi Highly sulfated maltooligosaccharides with heparin-like properties
US5739115A (en) * 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties
US5783568A (en) * 1994-06-10 1998-07-21 Sugen, Inc. Methods for treating cancer and other cell proliferative diseases
DK0852491T3 (da) * 1995-09-29 2004-12-20 Biomarin Pharm Inc Anvendelse af heparinaser til at mindske inflammatoriske responser
WO1997022347A1 (en) * 1995-12-18 1997-06-26 Stichting Sanquin Bloedvoorziening Potentiation of complement and coagulation inhibitory properties of c1-inhibitor.
CA2243543A1 (en) * 1996-01-26 1997-07-31 Research Institute For Glycotechnology Apoptosis inducers
CA2253573C (en) * 1996-06-12 2005-12-06 Takara Shuzo Co., Ltd. Fucoidan-containing foods or beverages
US8304390B2 (en) 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
US7151099B2 (en) 1998-07-31 2006-12-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7345039B2 (en) 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
WO2001013925A1 (fr) * 1999-08-20 2001-03-01 Takara Shuzo Co., Ltd. Medicaments
US6641571B2 (en) 2000-01-05 2003-11-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery
DE60210070T2 (de) 2001-04-16 2006-12-07 IVAX RESEARCH, INC., Miami Sulfatierte polysaccharide und verfahren zur behandlung von entzündungen unter verwendung derselben
CZ307433B6 (cs) 2001-09-12 2018-08-22 Leadiant Biosciences Sa Deriváty částečně desulfátovaných glykosaminoglykanů jako inhibitory heparanázy mající antiangiogenní účinky a zabraňující antikoagulačnímu působení
US7285536B2 (en) 2001-12-05 2007-10-23 Yeda Research And Development Co., Ltd. Anti-cancer therapeutic compounds
ITMI20021294A1 (it) * 2002-06-12 2003-12-12 Inalco Spa Polisaccaridi batterici o-solfatati e loro uso
US20050186645A1 (en) 2003-12-18 2005-08-25 Yehudit Amor Method for analyzing a glycomolecule
BRPI0511603A (pt) * 2004-05-27 2008-01-02 Avigen Inc método para o tratamento de distúrbios do sangramento com a utilização de polissacarìdeos sulfatados
JP5701498B2 (ja) * 2009-12-01 2015-04-15 公益財団法人微生物化学研究会 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物
JP5934735B2 (ja) * 2014-03-28 2016-06-15 株式会社オプトクリエーション ナノバブル・フコイダン水素水
NL2024493B1 (en) * 2019-12-16 2021-09-02 Logick Energetics B V Pharmaceutical composition for preventing or stopping metastases
WO2021125951A1 (en) 2019-12-18 2021-06-24 Logick Energetics B.V. Pharmaceutical composition for use in preventing or stopping metastases
WO2022265510A1 (en) * 2021-06-17 2022-12-22 Logick Energetics B.V. Pharmaceutical composition for use in the treatment of metastatic epithelial ovarian cancer, metastatic fallopian tube carcinoma or metastatic primary peritoneal carcinoma

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1730M (fr) * 1962-01-17 1963-03-18 Charles Riviere Nouvelle composition de collyre.
JPS5943929B2 (ja) * 1979-08-13 1984-10-25 サッポロビール株式会社 多糖体ｒｂｓ物質，その製法およびそれを有効成分とする抗腫瘍性剤
CA1226816A (en) * 1982-12-20 1987-09-15 Moses J. Folkman Inhibition of angiogenesis
AU555747B2 (en) * 1983-08-09 1986-10-09 Cilco Inc. Chondroitin sulfate and sodium hyaluronate composition
FR2553287B1 (fr) * 1983-10-18 1986-09-12 Choay Sa Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire
DE3422518A1 (de) * 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
US4710493A (en) * 1984-08-14 1987-12-01 Albert Landsberger Therapeutic agent for the use in cancer treatment
FR2584606A1 (fr) * 1985-07-12 1987-01-16 Dropic Utilisation de poly- et oligosaccharides pour l'obtention de medicaments actifs dans les pathologies du tissu conjonctif
IL79254A0 (en) * 1986-06-26 1986-09-30 Hadassah Med Org Compositions for preventing graft rejection
IL79255A0 (en) * 1986-06-26 1986-09-30 Hadassah Med Org Composition for metastasis prevention
JP2511829B2 (ja) * 1987-03-19 1996-07-03 アースロファーム ピーティーワイ．リミティッド 抗炎症作用のある化合物および組成物
JPH06157520A (ja) * 1992-11-13 1994-06-03 Kirin Brewery Co Ltd 新規物質ｈｑ２４

Also Published As

Publication number Publication date
DE3856083T2 (de) 1998-07-02
JP2752353B2 (ja) 1998-05-18
SG45156A1 (en) 1998-01-16
JP2701904B2 (ja) 1998-01-21
HK1014153A1 (en) 1999-09-24
ATE178212T1 (de) 1999-04-15
SG52246A1 (en) 1998-09-28
EP0355088B1 (de) 1997-12-10
EP0355088A1 (de) 1990-02-28
EP0631784A1 (de) 1995-01-04
CA1316828C (en) 1993-04-27
WO1988005301A1 (en) 1988-07-28
IL85145A (en) 1994-08-26
JPH02502006A (ja) 1990-07-05
ATE160941T1 (de) 1997-12-15
EP0631784B1 (de) 1999-03-31
JPH09328431A (ja) 1997-12-22
DE3856321T2 (de) 1999-08-26
EP0355088A4 (de) 1990-06-26
DE3856321D1 (de) 1999-05-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee