IL85004A - 1,4 dihydro-beta-oxo-1-substituted-(1)-benzo(thio)-pyrano-(4,3-c)pyrazole-3-poropanenitrile derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
1,4 dihydro-beta-oxo-1-substituted-(1)-benzo(thio)-pyrano-(4,3-c)pyrazole-3-poropanenitrile derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL85004A IL85004A IL85004A IL8500488A IL85004A IL 85004 A IL85004 A IL 85004A IL 85004 A IL85004 A IL 85004A IL 8500488 A IL8500488 A IL 8500488A IL 85004 A IL85004 A IL 85004A
- Authority
- IL
- Israel
- Prior art keywords
- poropanenitrile
- pyrano
- pyrazole
- benzo
- thio
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878700477A GB8700477D0 (en) | 1987-01-09 | 1987-01-09 | Heteroaryl 2-cyano-3-oxo-propanamide derivatives |
GB878717282A GB8717282D0 (en) | 1987-07-22 | 1987-07-22 | Heteroaryl 3-oxo-propanenitrile derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IL85004A0 IL85004A0 (en) | 1988-06-30 |
IL85004A true IL85004A (en) | 1991-11-21 |
Family
ID=26291768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL85004A IL85004A (en) | 1987-01-09 | 1988-01-01 | 1,4 dihydro-beta-oxo-1-substituted-(1)-benzo(thio)-pyrano-(4,3-c)pyrazole-3-poropanenitrile derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (23)
Country | Link |
---|---|
US (1) | US4816467A (hu) |
EP (1) | EP0274443B1 (hu) |
JP (1) | JP2672312B2 (hu) |
KR (1) | KR960002852B1 (hu) |
CN (1) | CN1025500C (hu) |
AU (1) | AU598893B2 (hu) |
CA (1) | CA1310647C (hu) |
CZ (1) | CZ277972B6 (hu) |
DE (1) | DE3862937D1 (hu) |
DK (1) | DK8088A (hu) |
ES (1) | ES2029003T3 (hu) |
FI (1) | FI89489C (hu) |
GR (1) | GR3002032T3 (hu) |
HU (1) | HU198722B (hu) |
IE (1) | IE60620B1 (hu) |
IL (1) | IL85004A (hu) |
MY (1) | MY103348A (hu) |
NO (1) | NO165841C (hu) |
NZ (1) | NZ223113A (hu) |
PH (1) | PH27000A (hu) |
PT (1) | PT86516B (hu) |
SU (1) | SU1695826A3 (hu) |
YU (2) | YU46787B (hu) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988007994A1 (en) * | 1987-04-09 | 1988-10-20 | E.I. Du Pont De Nemours And Company | Insecticidal substituted indazoles |
GB8814587D0 (en) * | 1988-06-20 | 1988-07-27 | Erba Carlo Spa | Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation |
GB8814586D0 (en) * | 1988-06-20 | 1988-07-27 | Erba Carlo Spa | Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation |
GB2227741B (en) * | 1989-02-06 | 1992-08-05 | Erba Carlo Spa | Condensed 3-oxo-propanenitrile derivatives and process for their preparation |
US5260328A (en) * | 1989-04-06 | 1993-11-09 | Farmitalia Carlo Erba Srl | Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis |
GB8907799D0 (en) * | 1989-04-06 | 1989-05-17 | Erba Carlo Spa | Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases |
GB8916290D0 (en) * | 1989-07-17 | 1989-08-31 | Erba Carlo Spa | Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis |
DE59010701D1 (de) * | 1990-05-18 | 1997-05-22 | Hoechst Ag | Isoxazol-4-carbonsäureamide und hydroxyalkyliden-cyanessigsäureamide, diese verbindungen enthaltende arzneimittel und deren verwendung |
US5547975A (en) * | 1994-09-20 | 1996-08-20 | Talley; John J. | Benzopyranopyrazolyl derivatives for the treatment of inflammation |
US5886016A (en) * | 1995-09-15 | 1999-03-23 | G.D. Searle & Co. | Benzopyranopyrazolyl derivatives for the treatment of inflammation |
GB9720899D0 (en) * | 1997-10-01 | 1997-12-03 | Pharmacia & Upjohn Spa | Condensed heterocyclic compounds |
CN100390288C (zh) * | 2000-04-11 | 2008-05-28 | 杰南技术公司 | 多价抗体及其应用 |
EP1427706B1 (en) * | 2001-09-19 | 2007-05-30 | Pharmacia Corporation | Substituted pyrazolo compounds for the treatment of inflammation |
EP1651276A4 (en) * | 2003-08-08 | 2009-05-06 | Barnes Jewish Hospital | EMULSION PARTICLES FOR IMAGING AND THERAPY AND USE METHOD THEREFOR |
US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
CA2650574A1 (en) * | 2006-04-27 | 2007-11-08 | Barnes-Jewish Hospital | Detection and imaging of target tissue |
EA201290305A1 (ru) * | 2009-11-13 | 2012-12-28 | Мерк Сероно С.А. | Производные трициклического пиразоламина |
CN102086212B (zh) * | 2009-12-03 | 2013-06-12 | 沈阳药科大学 | 抗真菌剂-2,3,4,5-四氢-4H-苯并[b]噻喃并[4,3-c]吡唑-2-甲酰胺衍生物 |
EP3525821A4 (en) | 2016-10-17 | 2020-09-09 | University of Maryland | MULTI-SPECIFIC ANTIBODIES TARGETING THE HUMAN IMMUNODEFICIENCY VIRUS AND THEIR METHODS OF USE |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4268516A (en) * | 1978-10-11 | 1981-05-19 | Pfizer Inc. | [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents |
EP0022446A1 (de) * | 1979-04-06 | 1981-01-21 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung von Biotinestern und von Biotin |
AU8029982A (en) * | 1981-02-11 | 1982-08-19 | E.I. Du Pont De Nemours And Company | 3,4-dihydro-(1,4-dihydro)-2 substituted-thio benzopyrano 3,4-d imidazoles |
PH21213A (en) * | 1984-10-26 | 1987-08-21 | Fujisawa Pharmaceutical Co | Benzene- and pyrazole- fused heterocyclic compound and pharmaceutical composition comprising the same |
-
1987
- 1987-12-31 US US07/140,221 patent/US4816467A/en not_active Expired - Fee Related
-
1988
- 1988-01-01 IL IL85004A patent/IL85004A/xx not_active IP Right Cessation
- 1988-01-04 IE IE288A patent/IE60620B1/en not_active IP Right Cessation
- 1988-01-04 PH PH36319A patent/PH27000A/en unknown
- 1988-01-05 AU AU10037/88A patent/AU598893B2/en not_active Ceased
- 1988-01-06 YU YU1088A patent/YU46787B/sh unknown
- 1988-01-07 CZ CS88179A patent/CZ277972B6/cs not_active IP Right Cessation
- 1988-01-07 NZ NZ223113A patent/NZ223113A/xx unknown
- 1988-01-07 CN CN88100153A patent/CN1025500C/zh not_active Expired - Fee Related
- 1988-01-07 CA CA000556010A patent/CA1310647C/en not_active Expired - Fee Related
- 1988-01-08 ES ES198888300115T patent/ES2029003T3/es not_active Expired - Lifetime
- 1988-01-08 HU HU8858A patent/HU198722B/hu not_active IP Right Cessation
- 1988-01-08 SU SU884355070A patent/SU1695826A3/ru active
- 1988-01-08 NO NO880068A patent/NO165841C/no unknown
- 1988-01-08 DK DK008088A patent/DK8088A/da not_active Application Discontinuation
- 1988-01-08 KR KR1019880000056A patent/KR960002852B1/ko active IP Right Grant
- 1988-01-08 PT PT86516A patent/PT86516B/pt not_active IP Right Cessation
- 1988-01-08 FI FI880078A patent/FI89489C/fi not_active IP Right Cessation
- 1988-01-08 EP EP88300115A patent/EP0274443B1/en not_active Expired - Lifetime
- 1988-01-08 JP JP63002374A patent/JP2672312B2/ja not_active Expired - Lifetime
- 1988-01-08 DE DE8888300115T patent/DE3862937D1/de not_active Expired - Fee Related
- 1988-01-08 MY MYPI88000014A patent/MY103348A/en unknown
-
1989
- 1989-04-18 YU YU00794/89A patent/YU79489A/xx unknown
-
1991
- 1991-05-30 GR GR91400684T patent/GR3002032T3/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |