IL84051A0 - 7-((meta-substituted)phenylglycine)1-carba-1-dethiacephalosporins - Google Patents

7-((meta-substituted)phenylglycine)1-carba-1-dethiacephalosporins

Info

Publication number
IL84051A0
IL84051A0 IL84051A IL8405187A IL84051A0 IL 84051 A0 IL84051 A0 IL 84051A0 IL 84051 A IL84051 A IL 84051A IL 8405187 A IL8405187 A IL 8405187A IL 84051 A0 IL84051 A0 IL 84051A0
Authority
IL
Israel
Prior art keywords
dethiacephalosporins
carba
phenylglycine
meta
substituted
Prior art date
Application number
IL84051A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL84051A0 publication Critical patent/IL84051A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
IL84051A 1986-10-03 1987-10-01 7-((meta-substituted)phenylglycine)1-carba-1-dethiacephalosporins IL84051A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91517386A 1986-10-03 1986-10-03

Publications (1)

Publication Number Publication Date
IL84051A0 true IL84051A0 (en) 1988-03-31

Family

ID=25435354

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84051A IL84051A0 (en) 1986-10-03 1987-10-01 7-((meta-substituted)phenylglycine)1-carba-1-dethiacephalosporins

Country Status (17)

Country Link
EP (1) EP0266896B1 (el)
JP (1) JPS6396186A (el)
KR (1) KR880005125A (el)
CN (1) CN87107149A (el)
AT (2) ATE79119T1 (el)
BG (1) BG47034A3 (el)
DE (1) DE3780909T2 (el)
DK (1) DK518487A (el)
FI (1) FI874311A (el)
GR (1) GR3005920T3 (el)
HU (1) HU200179B (el)
IE (1) IE872646L (el)
IL (1) IL84051A0 (el)
NZ (1) NZ222015A (el)
PL (1) PL151703B1 (el)
PT (1) PT85850B (el)
ZA (1) ZA877398B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA89829B (en) * 1988-02-05 1990-10-31 Lilly Co Eli Crystalline b-lactam solvate
IL157552A0 (en) 2001-03-28 2004-03-28 Schering Corp Enantioselective synthesis of azetidinone intermediate compounds
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
WO2004037163A2 (en) * 2002-05-14 2004-05-06 Northwestern University STERICALLY-AWKWARD β-LACTAMASE INHIBITORS
EP1601669B1 (en) 2003-03-07 2008-12-24 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
ES2311806T3 (es) 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
CN102144992B (zh) * 2011-03-10 2013-04-10 浙江大学 苯基甘氨酸衍生物制备对金黄色葡萄球菌有抑菌和杀菌活性的抗菌剂的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697515A (en) * 1963-02-18 1972-10-10 Ciba Geigy Corp Process for splitting the 7-n-acyl group from cephalosporin compounds
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
NO155547C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling.
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd 3位置換カルバセフエム化合物
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof

Also Published As

Publication number Publication date
IE872646L (en) 1988-04-03
ATA257587A (de) 1988-11-15
PT85850B (en) 1990-01-12
NZ222015A (en) 1989-10-27
PL268034A1 (en) 1988-09-01
BG47034A3 (en) 1990-04-16
AU591811B2 (en) 1989-12-14
ATE79119T1 (de) 1992-08-15
ZA877398B (en) 1989-05-30
JPS6396186A (ja) 1988-04-27
PT85850A (en) 1987-11-01
EP0266896B1 (en) 1992-08-05
DK518487D0 (da) 1987-10-02
DK518487A (da) 1988-04-04
HU200179B (en) 1990-04-28
AT388377B (de) 1989-06-12
KR880005125A (ko) 1988-06-28
DE3780909T2 (de) 1993-03-04
PL151703B1 (en) 1990-09-28
GR3005920T3 (el) 1993-06-07
AU7926987A (en) 1988-04-14
CN87107149A (zh) 1988-05-18
FI874311A (fi) 1988-04-04
DE3780909D1 (en) 1992-09-10
EP0266896A1 (en) 1988-05-11
HUT45053A (en) 1988-05-30
FI874311A0 (fi) 1987-10-01

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