IL83432A - N-phenylcarboxamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
N-phenylcarboxamide derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL83432A IL83432A IL83432A IL8343287A IL83432A IL 83432 A IL83432 A IL 83432A IL 83432 A IL83432 A IL 83432A IL 8343287 A IL8343287 A IL 8343287A IL 83432 A IL83432 A IL 83432A
- Authority
- IL
- Israel
- Prior art keywords
- phenylcarboxamide
- derivatives
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
- C07D261/16—Benzene-sulfonamido isoxazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868619432A GB8619432D0 (en) | 1986-08-08 | 1986-08-08 | Pharmaceutical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
IL83432A0 IL83432A0 (en) | 1988-01-31 |
IL83432A true IL83432A (en) | 1992-06-21 |
Family
ID=10602473
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL83432A IL83432A (en) | 1986-08-08 | 1987-08-04 | N-phenylcarboxamide derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (23)
Country | Link |
---|---|
US (1) | US4892963A (es) |
EP (1) | EP0257882B1 (es) |
JP (1) | JPS63239259A (es) |
KR (2) | KR880002815A (es) |
CN (1) | CN1015256B (es) |
AR (2) | AR244660A1 (es) |
AT (1) | ATE65494T1 (es) |
AU (1) | AU604737B2 (es) |
CA (1) | CA1317964C (es) |
DE (1) | DE3771611D1 (es) |
DK (1) | DK169404B1 (es) |
EG (1) | EG18269A (es) |
ES (1) | ES2031510T3 (es) |
GB (1) | GB8619432D0 (es) |
GR (1) | GR3002714T3 (es) |
HU (1) | HU197559B (es) |
IL (1) | IL83432A (es) |
MX (1) | MX174371B (es) |
NZ (1) | NZ221352A (es) |
PH (1) | PH22821A (es) |
PT (1) | PT85476B (es) |
RU (1) | RU1771472C (es) |
ZA (1) | ZA875813B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3534440A1 (de) * | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
US5268382A (en) * | 1985-09-27 | 1993-12-07 | Hoechst Aktiengesellschaft | Medicaments to combat autoimmune diseases, in particular systemic lupus erythematosus |
US4975462A (en) * | 1988-07-29 | 1990-12-04 | Bristol-Myers Company | Antiarthritic α-arylcarbamoyl cyanoacetic acid derivatives |
US5583150A (en) * | 1989-08-18 | 1996-12-10 | Alcon Laboratories, Inc. | 5-methyl-isoxazole-4-carboxylic acid anilides and 2-hydroxyethylidene-cyano acetic anilides for the treatment of ocular diseases |
DD297328A5 (de) * | 1989-08-18 | 1992-01-09 | �������@���������k���Kk�� | 5-methyl-isoxalol-4-carbonsaeureanilide und 2 hydroxyethyliden-cyanoessigsaeureanilide zur behandlung von augenerkrankungen |
US5001124A (en) * | 1990-02-02 | 1991-03-19 | Syntex (U.S.A.) Inc. | 4-isoxazolecarboxamide derivatives |
US5108999A (en) * | 1990-02-02 | 1992-04-28 | Syntex (U.S.A.) Inc. | 4-isoxazolecarboxamide derivatives |
JPH04211048A (ja) * | 1990-03-05 | 1992-08-03 | Mitsubishi Kasei Corp | チオカルバモイルアセトニトリル誘導体 |
DK0527736T3 (da) * | 1990-05-18 | 1997-10-20 | Hoechst Ag | Isoxazol-4-carboxylsyreamider og hydroxyalkyliden-cyanoacetamider, lægemidler indeholdende disse forbindelser og anvendelsen af disse lægemidler. |
IL102790A (en) * | 1991-09-17 | 1996-01-31 | Roussel Uclaf | History of 3-cycloalkyl-prop-2-anamide |
ATE128353T1 (de) * | 1991-10-23 | 1995-10-15 | Hoechst Ag | N-phenyl-2-cyano-3-hydroxycrotonsäureamidderiva e und deren verwendung als arzneimittel mit immunmodulatorischer eigenschaft. |
GB9200275D0 (en) * | 1992-01-08 | 1992-02-26 | Roussel Lab Ltd | Chemical compounds |
TW314467B (es) * | 1993-03-31 | 1997-09-01 | Hoechst Ag | |
WO1994024095A1 (en) * | 1993-04-16 | 1994-10-27 | Abbott Laboratories | Immunosuppressive agents |
GB9320299D0 (en) * | 1993-10-01 | 1993-11-17 | Roussel Lab Ltd | Isoxazole derivatives |
US5814649A (en) * | 1994-10-17 | 1998-09-29 | Hoechst Pharmaceuticals & Chemicals K.K. | Preventive and remedy for type 1 allergic diseases |
DE19702988A1 (de) | 1997-01-28 | 1998-07-30 | Hoechst Ag | Isoxazol- und Crotonsäureamidderivate und deren Verwendung als Arzneimittel und Diagnostika |
CN1411373A (zh) * | 1999-12-16 | 2003-04-16 | 特瓦制药工业有限公司 | 制备来氟米特的新方法和新晶形的来氟米特 |
ATE292966T1 (de) | 2000-02-15 | 2005-04-15 | Teva Pharma | Methode zur synthetisierung von leflunomid |
DE10311763A1 (de) * | 2003-03-18 | 2004-10-07 | Aventis Pharma Deutschland Gmbh | Verfahren zur Herstellung von 2-Cyan-3-hydroxy-N-(phenyl)but-2-enamiden |
US6894184B2 (en) | 2003-03-18 | 2005-05-17 | Aventis Pharma Deutschland Gmbh | Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides |
CN105916522A (zh) | 2013-11-22 | 2016-08-31 | 建新公司 | 用于治疗神经变性疾病的新方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL186239B (nl) * | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
DK545976A (da) * | 1975-12-11 | 1977-06-12 | Hoechst Ag | Cyaneddikesyreanilidderivater fremgangsmade til deres fremstilling og midler der indeholder disse forbindelser |
DE2654797A1 (de) * | 1976-12-03 | 1978-06-08 | Hoechst Ag | Verfahren zur herstellung von isoxazolderivaten |
DE2655009A1 (de) * | 1976-12-04 | 1978-06-15 | Hoechst Ag | Isoxazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
ATE14724T1 (de) * | 1979-06-11 | 1985-08-15 | Ciba Geigy Ag | Alphacarbamoyl-pyrrolpropionitrile, verfahren zu ihrer herstellung, sowie pharmazeutische praeparate die diese verbindungen enthalten. |
-
1986
- 1986-08-08 GB GB868619432A patent/GB8619432D0/en active Pending
-
1987
- 1987-08-02 EG EG448/87A patent/EG18269A/xx active
- 1987-08-03 PH PH35615A patent/PH22821A/en unknown
- 1987-08-04 PT PT85476A patent/PT85476B/pt not_active IP Right Cessation
- 1987-08-04 IL IL83432A patent/IL83432A/xx not_active IP Right Cessation
- 1987-08-05 NZ NZ221352A patent/NZ221352A/xx unknown
- 1987-08-05 CA CA000543739A patent/CA1317964C/en not_active Expired - Fee Related
- 1987-08-06 DE DE8787306988T patent/DE3771611D1/de not_active Expired - Fee Related
- 1987-08-06 MX MX007668A patent/MX174371B/es unknown
- 1987-08-06 RU SU874203189A patent/RU1771472C/ru active
- 1987-08-06 ES ES198787306988T patent/ES2031510T3/es not_active Expired - Lifetime
- 1987-08-06 EP EP87306988A patent/EP0257882B1/en not_active Expired - Lifetime
- 1987-08-06 ZA ZA875813A patent/ZA875813B/xx unknown
- 1987-08-06 AT AT87306988T patent/ATE65494T1/de active
- 1987-08-07 US US07/083,538 patent/US4892963A/en not_active Expired - Fee Related
- 1987-08-07 DK DK413987A patent/DK169404B1/da not_active IP Right Cessation
- 1987-08-07 AU AU76681/87A patent/AU604737B2/en not_active Ceased
- 1987-08-07 AR AR87308368A patent/AR244660A1/es active
- 1987-08-07 HU HU873604A patent/HU197559B/hu not_active IP Right Cessation
- 1987-08-07 KR KR1019870008650A patent/KR880002815A/ko not_active Application Discontinuation
- 1987-08-07 CN CN87105516A patent/CN1015256B/zh not_active Expired
- 1987-08-07 JP JP62198006A patent/JPS63239259A/ja active Pending
- 1987-08-07 KR KR1019870008651A patent/KR880002823A/ko not_active Application Discontinuation
-
1991
- 1991-09-12 GR GR91401318T patent/GR3002714T3/el unknown
-
1992
- 1992-11-20 AR AR92323708A patent/AR247876A1/es active
Also Published As
Publication number | Publication date |
---|---|
PT85476A (en) | 1987-09-01 |
HU197559B (en) | 1989-04-28 |
AU604737B2 (en) | 1991-01-03 |
ES2031510T3 (es) | 1992-12-16 |
HUT44523A (en) | 1988-03-28 |
AU7668187A (en) | 1988-02-11 |
GR3002714T3 (en) | 1993-01-25 |
KR880002823A (ko) | 1988-05-11 |
ATE65494T1 (de) | 1991-08-15 |
IL83432A0 (en) | 1988-01-31 |
PH22821A (en) | 1989-01-19 |
CN87105516A (zh) | 1988-02-24 |
EG18269A (en) | 1992-12-30 |
DE3771611D1 (de) | 1991-08-29 |
JPS63239259A (ja) | 1988-10-05 |
CA1317964C (en) | 1993-05-18 |
MX7668A (es) | 1993-08-01 |
PT85476B (pt) | 1990-06-29 |
KR880002815A (ko) | 1988-05-11 |
ZA875813B (en) | 1989-04-26 |
AR247876A1 (es) | 1995-04-28 |
AR244660A1 (es) | 1993-11-30 |
EP0257882B1 (en) | 1991-07-24 |
US4892963A (en) | 1990-01-09 |
GB8619432D0 (en) | 1986-09-17 |
MX174371B (es) | 1994-05-11 |
CN1015256B (zh) | 1992-01-01 |
EP0257882A1 (en) | 1988-03-02 |
DK413987A (da) | 1988-02-09 |
NZ221352A (en) | 1989-10-27 |
RU1771472C (ru) | 1992-10-23 |
DK169404B1 (da) | 1994-10-24 |
DK413987D0 (da) | 1987-08-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |