IL82896A - N-(4-((2-amino-4(3h)-oxo-5,6,7,8-tetrahydropyrido(2,3-d)-pyrimidin-6-ylmethyl)amino)-benzoyl)-glutamic acid derivatives,their preparation and pharmaceutical compositions containing them and some intermediates therefor - Google Patents
N-(4-((2-amino-4(3h)-oxo-5,6,7,8-tetrahydropyrido(2,3-d)-pyrimidin-6-ylmethyl)amino)-benzoyl)-glutamic acid derivatives,their preparation and pharmaceutical compositions containing them and some intermediates thereforInfo
- Publication number
- IL82896A IL82896A IL82896A IL8289687A IL82896A IL 82896 A IL82896 A IL 82896A IL 82896 A IL82896 A IL 82896A IL 8289687 A IL8289687 A IL 8289687A IL 82896 A IL82896 A IL 82896A
- Authority
- IL
- Israel
- Prior art keywords
- amino
- tetrahydropyrido
- pyrimidin
- ylmethyl
- benzoyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87993586A | 1986-06-30 | 1986-06-30 | |
| US07/040,330 US4831037A (en) | 1987-04-20 | 1987-04-20 | 4 (3H)-oxo-5,6,7,8-tetrahydropyrido-(2,3-d)pyrimidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL82896A0 IL82896A0 (en) | 1987-12-20 |
| IL82896A true IL82896A (en) | 1991-06-10 |
Family
ID=26716970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL82896A IL82896A (en) | 1986-06-30 | 1987-06-16 | N-(4-((2-amino-4(3h)-oxo-5,6,7,8-tetrahydropyrido(2,3-d)-pyrimidin-6-ylmethyl)amino)-benzoyl)-glutamic acid derivatives,their preparation and pharmaceutical compositions containing them and some intermediates therefor |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0255228B1 (ja) |
| JP (1) | JPH07116189B2 (ja) |
| KR (1) | KR950001017B1 (ja) |
| CN (1) | CN1014895B (ja) |
| AU (1) | AU594163B2 (ja) |
| CA (1) | CA1301156C (ja) |
| DE (1) | DE3769721D1 (ja) |
| DK (1) | DK172896B1 (ja) |
| EG (1) | EG18301A (ja) |
| ES (2) | ES2031894T3 (ja) |
| GR (1) | GR870943B (ja) |
| HU (1) | HU198482B (ja) |
| IE (1) | IE60038B1 (ja) |
| IL (1) | IL82896A (ja) |
| NZ (1) | NZ220871A (ja) |
| PT (1) | PT85090B (ja) |
| SU (1) | SU1581222A3 (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8625019D0 (en) * | 1986-10-18 | 1986-11-19 | Wellcome Found | Compounds |
| JP2830008B2 (ja) * | 1988-04-01 | 1998-12-02 | 武田薬品工業株式会社 | 縮合ピリミジン誘導体 |
| US5223620A (en) * | 1988-04-01 | 1993-06-29 | Takeda Chemical Industries, Ltd. | Pyrido[2,3-d]pyrimidine compounds useful as intermediates |
| DK172753B1 (da) * | 1988-05-25 | 1999-06-28 | Lilly Co Eli | N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat |
| US4871746A (en) * | 1988-05-31 | 1989-10-03 | The Trustees Of Princeton University | N-[N-(tetrahydropyrido[2,3-D]pyrimidinylmethyl)-aminomethylbenzoyl]glutamic acid derivatives as neoplastic growth inhibitors |
| JP3015957B2 (ja) * | 1989-05-29 | 2000-03-06 | 武田薬品工業株式会社 | ピロロ［２，３―ｄ］ピリミジン誘導体およびその製造法 |
| US5159079A (en) * | 1991-12-20 | 1992-10-27 | Eli Lilly And Company | 2-piperidones as intermediates for 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids |
| WO1993020075A1 (en) * | 1992-04-01 | 1993-10-14 | The University Of Sydney | 8-substituted-n5-deazapterins as antifolates |
| CN1962658B (zh) * | 2005-11-10 | 2010-05-12 | 北京大学 | 一种四氢吡啶并[3,2-d]嘧啶类化合物及制备抗肿瘤药物的用途 |
| EP3370659A1 (en) | 2015-11-06 | 2018-09-12 | Avent, Inc. | Ostomy device, apparatus, and system |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3276808D1 (de) * | 1981-09-25 | 1987-08-27 | Southern Res Inst | Pyrido (2,3-d) pyrimidines |
| ZA861235B (en) * | 1985-03-08 | 1986-10-29 | Univ Princeton | Pyrido(2,3-d)pyrimidine derivatives |
| NZ219971A (en) * | 1986-06-06 | 1989-08-29 | Univ Princeton | Tetrahydropyrido (2,3-d pyrimidine derivatives and pharmaceutical compositions |
-
1987
- 1987-06-15 IE IE158687A patent/IE60038B1/en not_active IP Right Cessation
- 1987-06-16 IL IL82896A patent/IL82896A/xx not_active IP Right Cessation
- 1987-06-16 GR GR870943A patent/GR870943B/el unknown
- 1987-06-16 CA CA000539751A patent/CA1301156C/en not_active Expired - Lifetime
- 1987-06-16 PT PT85090A patent/PT85090B/pt unknown
- 1987-06-16 AU AU74262/87A patent/AU594163B2/en not_active Ceased
- 1987-06-17 DK DK198703073A patent/DK172896B1/da not_active IP Right Cessation
- 1987-06-23 JP JP62156387A patent/JPH07116189B2/ja not_active Expired - Lifetime
- 1987-06-24 EP EP87305636A patent/EP0255228B1/en not_active Expired - Lifetime
- 1987-06-24 ES ES198787305636T patent/ES2031894T3/es not_active Expired - Lifetime
- 1987-06-24 DE DE8787305636T patent/DE3769721D1/de not_active Expired - Lifetime
- 1987-06-24 EG EG367/87A patent/EG18301A/xx active
- 1987-06-25 KR KR1019870006506A patent/KR950001017B1/ko not_active IP Right Cessation
- 1987-06-26 SU SU874202827A patent/SU1581222A3/ru active
- 1987-06-29 NZ NZ220871A patent/NZ220871A/xx unknown
- 1987-06-29 HU HU872927A patent/HU198482B/hu not_active IP Right Cessation
- 1987-06-29 ES ES8701888A patent/ES2007064A6/es not_active Expired
- 1987-06-30 CN CN87104596A patent/CN1014895B/zh not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HUT44548A (en) | 1988-03-28 |
| DE3769721D1 (de) | 1991-06-06 |
| IL82896A0 (en) | 1987-12-20 |
| DK172896B1 (da) | 1999-09-20 |
| ES2007064A6 (es) | 1989-06-01 |
| JPS6333379A (ja) | 1988-02-13 |
| PT85090B (pt) | 1990-03-08 |
| DK307387D0 (da) | 1987-06-17 |
| ES2031894T3 (es) | 1993-01-01 |
| CN87104596A (zh) | 1988-01-20 |
| DK307387A (da) | 1987-12-31 |
| CA1301156C (en) | 1992-05-19 |
| HU198482B (en) | 1989-10-30 |
| JPH07116189B2 (ja) | 1995-12-13 |
| KR880000432A (ko) | 1988-03-25 |
| IE60038B1 (en) | 1994-05-18 |
| GR870943B (en) | 1987-10-19 |
| EP0255228B1 (en) | 1991-05-02 |
| NZ220871A (en) | 1989-07-27 |
| EG18301A (en) | 1993-02-28 |
| PT85090A (en) | 1987-07-01 |
| SU1581222A3 (ru) | 1990-07-23 |
| IE871586L (en) | 1987-12-30 |
| EP0255228A1 (en) | 1988-02-03 |
| AU7426287A (en) | 1988-01-07 |
| KR950001017B1 (ko) | 1995-02-07 |
| CN1014895B (zh) | 1991-11-27 |
| AU594163B2 (en) | 1990-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |