IL81268A0 - Fused benzazepines,process for preparing them and pharmaceutical compositions containing them - Google Patents

Fused benzazepines,process for preparing them and pharmaceutical compositions containing them

Info

Publication number
IL81268A0
IL81268A0 IL81268A IL8126887A IL81268A0 IL 81268 A0 IL81268 A0 IL 81268A0 IL 81268 A IL81268 A IL 81268A IL 8126887 A IL8126887 A IL 8126887A IL 81268 A0 IL81268 A0 IL 81268A0
Authority
IL
Israel
Prior art keywords
preparing
pharmaceutical compositions
compositions containing
fused benzazepines
benzazepines
Prior art date
Application number
IL81268A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to IL103006A priority Critical patent/IL103006A/xx
Publication of IL81268A0 publication Critical patent/IL81268A0/xx
Priority to IL103006A priority patent/IL103006A0/xx
Priority to IL103007A priority patent/IL103007A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL81268A 1986-01-16 1987-01-15 Fused benzazepines,process for preparing them and pharmaceutical compositions containing them IL81268A0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL103006A IL103006A (en) 1986-01-16 1987-01-15 Condensed heterocyclic amine derivatives and their preparation
IL103006A IL103006A0 (en) 1986-01-16 1992-08-31 Heterocyclic compounds and their preparation
IL103007A IL103007A0 (en) 1986-01-16 1992-08-31 Heterocyclic compounds and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82047186A 1986-01-16 1986-01-16

Publications (1)

Publication Number Publication Date
IL81268A0 true IL81268A0 (en) 1987-08-31

Family

ID=25230864

Family Applications (2)

Application Number Title Priority Date Filing Date
IL81268A IL81268A0 (en) 1986-01-16 1987-01-15 Fused benzazepines,process for preparing them and pharmaceutical compositions containing them
IL103007A IL103007A (en) 1986-01-16 1987-01-15 Condensed (hetero)cyclic amine derivatives and their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL103007A IL103007A (en) 1986-01-16 1987-01-15 Condensed (hetero)cyclic amine derivatives and their preparation

Country Status (19)

Country Link
EP (2) EP0254737B1 (fr)
JP (1) JPH0681745B2 (fr)
KR (1) KR900007781B1 (fr)
AU (1) AU588080B2 (fr)
CA (1) CA1333485C (fr)
CS (1) CS414091A3 (fr)
DK (1) DK164161C (fr)
ES (1) ES2031834T3 (fr)
FI (1) FI83512C (fr)
GR (1) GR3000994T3 (fr)
HU (1) HU199805B (fr)
IE (1) IE59651B1 (fr)
IL (2) IL81268A0 (fr)
NZ (1) NZ218953A (fr)
OA (1) OA08660A (fr)
PT (1) PT84109B (fr)
SG (1) SG128692G (fr)
WO (1) WO1987004430A2 (fr)
ZA (1) ZA87291B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973586A (en) 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
ATE78467T1 (de) * 1987-07-15 1992-08-15 Schering Corp Kondensierte benzazepine.
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
HUT58035A (en) * 1988-07-29 1992-01-28 Schering Corp Process for enanthiospecific synthesis of intermediates of hexahydrobenzo(d)naphtno(2,1-b)azepines
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
US5104814A (en) * 1988-11-22 1992-04-14 Schering Corporation Assay kit and methods for neuroleptic drugs
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
WO1991011437A1 (fr) * 1990-02-02 1991-08-08 Schering Corporation Derives de 4,5-cycloalcano-3-benzazepin-7-ol et leurs utilisations
US5461148A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461147A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5463051A (en) * 1993-09-27 1995-10-31 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
AR027687A1 (es) * 2000-03-22 2003-04-09 Yakult Honsha Kk Procedimiento para preparar camptotecina
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
US7211574B2 (en) 2002-08-29 2007-05-01 Schering Corporation Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders
WO2005035504A2 (fr) * 2003-05-22 2005-04-21 Schering Corporation Antagonistes selectifs des recepteurs d1/d5 utilises dans le traitement de l'obesite et des troubles du systeme nerveux central
JP5513378B2 (ja) 2007-06-15 2014-06-04 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド 治療化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
GB1118688A (en) 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
US3609138A (en) 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines
NL7206204A (fr) * 1971-05-10 1972-11-14
US3939165A (en) * 1974-11-14 1976-02-17 Morton-Norwich Products, Inc. 5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en) 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en) 1979-04-27 1981-08-18 Schering Corporation 7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en) 1980-02-05 1984-10-16 Schering Corp. Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
FI874006A0 (fi) 1987-09-15
FI83512B (fi) 1991-04-15
AU588080B2 (en) 1989-09-07
IE870112L (en) 1987-07-16
FI83512C (fi) 1991-07-25
WO1987004430A3 (fr) 1988-03-24
ZA87291B (en) 1987-11-25
IL103007A (en) 1993-07-08
OA08660A (en) 1988-11-30
WO1987004430A2 (fr) 1987-07-30
HUT48600A (en) 1989-06-28
DK164161B (da) 1992-05-18
EP0230270A2 (fr) 1987-07-29
CA1333485C (fr) 1994-12-13
IE59651B1 (en) 1994-03-09
CS414091A3 (en) 1992-05-13
EP0230270B1 (fr) 1990-08-01
JPH0681745B2 (ja) 1994-10-19
NZ218953A (en) 1990-03-27
AU6892087A (en) 1987-08-14
SG128692G (en) 1993-03-12
PT84109B (pt) 1989-07-31
KR900007781B1 (ko) 1990-10-20
EP0230270A3 (en) 1987-10-21
GR3000994T3 (en) 1991-12-10
JPS63502348A (ja) 1988-09-08
EP0254737B1 (fr) 1990-07-25
ES2031834T3 (es) 1993-01-01
KR880700794A (ko) 1988-04-12
EP0254737A1 (fr) 1988-02-03
DK164161C (da) 1992-10-26
PT84109A (en) 1987-02-01
HU199805B (en) 1990-03-28
FI874006A (fi) 1987-09-15
DK479087A (da) 1987-09-14
DK479087D0 (da) 1987-09-14

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Legal Events

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