DK479087D0 - Kondenserede benzazepiner - Google Patents

Kondenserede benzazepiner

Info

Publication number
DK479087D0
DK479087D0 DK479087A DK479087A DK479087D0 DK 479087 D0 DK479087 D0 DK 479087D0 DK 479087 A DK479087 A DK 479087A DK 479087 A DK479087 A DK 479087A DK 479087 D0 DK479087 D0 DK 479087D0
Authority
DK
Denmark
Prior art keywords
benzazepines
condensed
condensed benzazepines
Prior art date
Application number
DK479087A
Other languages
English (en)
Other versions
DK164161C (da
DK164161B (da
DK479087A (da
Inventor
Joel Gilbert Berger
Wei Kong Chang
Elijah Herman Gold
John Welch Clader
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK479087D0 publication Critical patent/DK479087D0/da
Publication of DK479087A publication Critical patent/DK479087A/da
Publication of DK164161B publication Critical patent/DK164161B/da
Application granted granted Critical
Publication of DK164161C publication Critical patent/DK164161C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK479087A 1986-01-16 1987-09-14 Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater DK164161C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US82047186A 1986-01-16 1986-01-16
US82047186 1986-01-16
PCT/US1987/000042 WO1987004430A2 (en) 1986-01-16 1987-01-14 Fused benzazepines
US8700042 1987-01-14

Publications (4)

Publication Number Publication Date
DK479087D0 true DK479087D0 (da) 1987-09-14
DK479087A DK479087A (da) 1987-09-14
DK164161B DK164161B (da) 1992-05-18
DK164161C DK164161C (da) 1992-10-26

Family

ID=25230864

Family Applications (1)

Application Number Title Priority Date Filing Date
DK479087A DK164161C (da) 1986-01-16 1987-09-14 Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater

Country Status (19)

Country Link
EP (2) EP0254737B1 (da)
JP (1) JPH0681745B2 (da)
KR (1) KR900007781B1 (da)
AU (1) AU588080B2 (da)
CA (1) CA1333485C (da)
CS (1) CS414091A3 (da)
DK (1) DK164161C (da)
ES (1) ES2031834T3 (da)
FI (1) FI83512C (da)
GR (1) GR3000994T3 (da)
HU (1) HU199805B (da)
IE (1) IE59651B1 (da)
IL (2) IL81268A0 (da)
NZ (1) NZ218953A (da)
OA (1) OA08660A (da)
PT (1) PT84109B (da)
SG (1) SG128692G (da)
WO (1) WO1987004430A2 (da)
ZA (1) ZA87291B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973586A (en) 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
ZA875183B (en) * 1987-07-15 1988-04-08 Schering Corporation Fused benzazepines
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
JPH03505735A (ja) * 1988-07-29 1991-12-12 シェリング・コーポレーション ヘキサヒドロ―ベンゾ［ｄ］―ナフト［２，１―ｂ］アゼピンのための中間体の対掌体特異的合成のための方法
US5104814A (en) * 1988-11-22 1992-04-14 Schering Corporation Assay kit and methods for neuroleptic drugs
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
US5362728A (en) * 1990-02-02 1994-11-08 Schering Corporation 4,5-bridged-2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols and derivatives and compositions and methods employing such compounds
US5461147A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461148A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5463051A (en) * 1993-09-27 1995-10-31 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
AR027687A1 (es) * 2000-03-22 2003-04-09 Yakult Honsha Kk Procedimiento para preparar camptotecina
AU2003217676B2 (en) 2002-02-22 2009-06-11 Takeda Pharmaceutical Company Limited Active agent delivery systems and methods for protecting and administering active agents
CN1688584A (zh) * 2002-08-29 2005-10-26 先灵公司 治疗肥胖和中枢神经系统疾病的选择性d1/d5受体拮抗剂
JP2006526021A (ja) * 2003-05-22 2006-11-16 シェーリング　コーポレイション 肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体
WO2008156707A1 (en) 2007-06-15 2008-12-24 University Of Florida Research Foundation Therapeutic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
GB1118688A (en) 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
US3609138A (en) 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines
IL39380A0 (en) * 1971-05-10 1972-07-26 Sparamedica Ag Benzazepine derivatives and their preparation
US3939165A (en) * 1974-11-14 1976-02-17 Morton-Norwich Products, Inc. 5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en) 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en) 1979-04-27 1981-08-18 Schering Corporation 7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en) 1980-02-05 1984-10-16 Schering Corp. Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
WO1987004430A2 (en) 1987-07-30
PT84109B (pt) 1989-07-31
HUT48600A (en) 1989-06-28
FI874006A0 (fi) 1987-09-15
DK164161C (da) 1992-10-26
WO1987004430A3 (en) 1988-03-24
ES2031834T3 (es) 1993-01-01
FI83512B (fi) 1991-04-15
AU6892087A (en) 1987-08-14
CA1333485C (en) 1994-12-13
HU199805B (en) 1990-03-28
EP0254737B1 (en) 1990-07-25
GR3000994T3 (en) 1991-12-10
IL103007A (en) 1993-07-08
OA08660A (en) 1988-11-30
JPS63502348A (ja) 1988-09-08
EP0254737A1 (en) 1988-02-03
IL81268A0 (en) 1987-08-31
ZA87291B (en) 1987-11-25
PT84109A (en) 1987-02-01
EP0230270A2 (en) 1987-07-29
JPH0681745B2 (ja) 1994-10-19
IE870112L (en) 1987-07-16
AU588080B2 (en) 1989-09-07
NZ218953A (en) 1990-03-27
KR880700794A (ko) 1988-04-12
FI83512C (fi) 1991-07-25
SG128692G (en) 1993-03-12
DK164161B (da) 1992-05-18
FI874006A (fi) 1987-09-15
DK479087A (da) 1987-09-14
IE59651B1 (en) 1994-03-09
CS414091A3 (en) 1992-05-13
EP0230270A3 (en) 1987-10-21
KR900007781B1 (ko) 1990-10-20
EP0230270B1 (en) 1990-08-01

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PBP Patent lapsed