IL81261A - Chroman and thiochroman 4-hydroxyacetic acid derivatives for the treatment of diabetic complications - Google Patents

Chroman and thiochroman 4-hydroxyacetic acid derivatives for the treatment of diabetic complications

Info

Publication number
IL81261A
IL81261A IL81261A IL8126187A IL81261A IL 81261 A IL81261 A IL 81261A IL 81261 A IL81261 A IL 81261A IL 8126187 A IL8126187 A IL 8126187A IL 81261 A IL81261 A IL 81261A
Authority
IL
Israel
Prior art keywords
thiochroman
chroman
treatment
diabetic complications
acid derivatives
Prior art date
Application number
IL81261A
Other languages
English (en)
Other versions
IL81261A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL81261A0 publication Critical patent/IL81261A0/xx
Publication of IL81261A publication Critical patent/IL81261A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
IL81261A 1986-01-17 1987-01-14 Chroman and thiochroman 4-hydroxyacetic acid derivatives for the treatment of diabetic complications IL81261A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/000091 WO1987004344A1 (fr) 1986-01-17 1986-01-17 Derives de l'acide hydroxyacetique pour le traitement de complications diabetiques

Publications (2)

Publication Number Publication Date
IL81261A0 IL81261A0 (en) 1987-08-31
IL81261A true IL81261A (en) 1992-05-25

Family

ID=22195340

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81261A IL81261A (en) 1986-01-17 1987-01-14 Chroman and thiochroman 4-hydroxyacetic acid derivatives for the treatment of diabetic complications

Country Status (26)

Country Link
US (1) US4853410A (fr)
EP (1) EP0230379B1 (fr)
JP (1) JPS62169775A (fr)
KR (1) KR890004104B1 (fr)
CN (1) CN1015545B (fr)
AT (1) ATE62237T1 (fr)
AU (1) AU574001B2 (fr)
CA (1) CA1283119C (fr)
DD (1) DD266735A5 (fr)
DE (1) DE3768966D1 (fr)
DK (1) DK21687A (fr)
EG (1) EG18353A (fr)
ES (1) ES2022319B3 (fr)
FI (1) FI94636C (fr)
GR (1) GR3001863T3 (fr)
HU (1) HU206618B (fr)
IE (1) IE59450B1 (fr)
IL (1) IL81261A (fr)
NO (1) NO171411C (fr)
NZ (1) NZ218970A (fr)
PH (2) PH22231A (fr)
PL (1) PL148082B1 (fr)
PT (1) PT84107B (fr)
WO (1) WO1987004344A1 (fr)
YU (1) YU46042B (fr)
ZA (1) ZA87309B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84806B (pt) * 1986-05-03 1989-12-29 Beecham Group Plc Processo para a preparacao de benzopiranos
AU2440599A (en) * 1998-02-25 1999-09-15 Shionogi & Co., Ltd. Therapeutic agent for complication of diabetes
AT502844B1 (de) * 2005-12-12 2007-08-15 Fronius Int Gmbh Schweissbrenner und endstück sowie kontaktrohr für einen schweissbrenner
EP2356100A1 (fr) * 2008-10-02 2011-08-17 Cambrex Karlskoga AB Nouveau procédé pour la préparation de dicétones et de médicaments
CN105924425B (zh) * 2016-04-29 2018-06-05 浙江师范大学 一种制备二氢硫色满衍生物的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3359161A (en) * 1963-08-29 1967-12-19 Kefalas As Thiaxanthenols, process of producing and anti-tussive compositions thereof
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
US4210663A (en) * 1978-11-08 1980-07-01 Pfizer Inc. Halogen substituted benzopyran- and benzothiopyran-4-carboxylic acids
US4286098A (en) * 1980-03-28 1981-08-25 Pfizer Inc. Process for the preparation of chiral hydantoins
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
US4305955A (en) * 1980-10-21 1981-12-15 Pfizer Inc. Carboxylic acid therapeutic agents
EP0065392B1 (fr) * 1981-05-13 1985-02-13 Imperial Chemical Industries Plc Compositions pharmaceutiques contenant des dérivés de la spiro-succinimide
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds

Also Published As

Publication number Publication date
NO171411B (no) 1992-11-30
US4853410A (en) 1989-08-01
EG18353A (en) 1993-02-28
YU5787A (en) 1988-04-30
EP0230379A3 (en) 1988-10-05
ATE62237T1 (de) 1991-04-15
ZA87309B (fr) 1988-07-18
DD266735A5 (de) 1989-04-12
PL263678A1 (en) 1988-04-14
WO1987004344A1 (fr) 1987-07-30
JPS62169775A (ja) 1987-07-25
ES2022319B3 (es) 1991-12-01
EP0230379A2 (fr) 1987-07-29
AU6764187A (en) 1987-07-30
CN1015545B (zh) 1992-02-19
KR870007149A (ko) 1987-08-17
CN87100191A (zh) 1987-09-09
HUT48230A (en) 1989-05-29
EP0230379B1 (fr) 1991-04-03
NO171411C (no) 1993-03-10
FI873843A0 (fi) 1987-09-04
IL81261A0 (en) 1987-08-31
IE870131L (en) 1987-07-17
PL148082B1 (en) 1989-09-30
HU206618B (en) 1992-12-28
NZ218970A (en) 1988-11-29
KR890004104B1 (ko) 1989-10-20
PT84107B (pt) 1989-07-31
DK21687D0 (da) 1987-01-16
DE3768966D1 (de) 1991-05-08
DK21687A (da) 1987-07-18
FI94636C (fi) 1995-10-10
JPH0586952B2 (fr) 1993-12-14
GR3001863T3 (en) 1992-11-23
YU46042B (sh) 1992-12-21
FI873843A (fi) 1987-09-04
NO873854L (no) 1987-09-15
FI94636B (fi) 1995-06-30
IE59450B1 (en) 1994-02-23
PH22231A (en) 1988-07-01
NO873854D0 (no) 1987-09-15
CA1283119C (fr) 1991-04-16
AU574001B2 (en) 1988-06-23
PH24703A (en) 1990-10-01
PT84107A (en) 1987-02-01

Similar Documents

Publication Publication Date Title
AU1331588A (en) Method for treatment of alcohol abuse
PH30797A (en) New chroman and thiochroman derivatives.
ES2017498B3 (es) Derivado de 2-fenilbenzoxepina.
AU3331889A (en) 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases
HUT54345A (en) Process for producing new, antiarrhythmic, sulfur-containing cyanophenol derivatives and medical compositions comprising same
IL81261A (en) Chroman and thiochroman 4-hydroxyacetic acid derivatives for the treatment of diabetic complications
DE69015910D1 (de) Pharmazeutische Verwendung von Fettsäuren.
GR3025530T3 (en) Antihypertensive benzopyran derivatives
AU3929789A (en) New 6-fluoro-3,5-dihydroxy carboxylic acids and derivatives thereof, a process for the preparation thereof, the use thereof as medicinal agents, pharmaceutical products and intermediates
NO169717C (no) Fremgangsmaate for fremstilling av et stabilt hydrat av etpenicillinderivat.
HU9301129D0 (en) Method for producing 2r,3s-malic acid derivatives

Legal Events

Date Code Title Description
RH Patent void