DE3768966D1 - Chroman- und thiochroman-4-essigsaeuren, verwendbar bei der behandlung von zuckerkrankheitskomplikationen. - Google Patents

Chroman- und thiochroman-4-essigsaeuren, verwendbar bei der behandlung von zuckerkrankheitskomplikationen.

Info

Publication number
DE3768966D1
DE3768966D1 DE8787300327T DE3768966T DE3768966D1 DE 3768966 D1 DE3768966 D1 DE 3768966D1 DE 8787300327 T DE8787300327 T DE 8787300327T DE 3768966 T DE3768966 T DE 3768966T DE 3768966 D1 DE3768966 D1 DE 3768966D1
Authority
DE
Germany
Prior art keywords
thiochroman
chroman
treatment
acetic acids
disease complications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787300327T
Other languages
English (en)
Inventor
Christopher Andrew Lipinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3768966D1 publication Critical patent/DE3768966D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DE8787300327T 1986-01-17 1987-01-15 Chroman- und thiochroman-4-essigsaeuren, verwendbar bei der behandlung von zuckerkrankheitskomplikationen. Expired - Fee Related DE3768966D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/000091 WO1987004344A1 (en) 1986-01-17 1986-01-17 Hydroxyacetic acid derivatives for the treatment of diabetic complications

Publications (1)

Publication Number Publication Date
DE3768966D1 true DE3768966D1 (de) 1991-05-08

Family

ID=22195340

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787300327T Expired - Fee Related DE3768966D1 (de) 1986-01-17 1987-01-15 Chroman- und thiochroman-4-essigsaeuren, verwendbar bei der behandlung von zuckerkrankheitskomplikationen.

Country Status (26)

Country Link
US (1) US4853410A (de)
EP (1) EP0230379B1 (de)
JP (1) JPS62169775A (de)
KR (1) KR890004104B1 (de)
CN (1) CN1015545B (de)
AT (1) ATE62237T1 (de)
AU (1) AU574001B2 (de)
CA (1) CA1283119C (de)
DD (1) DD266735A5 (de)
DE (1) DE3768966D1 (de)
DK (1) DK21687A (de)
EG (1) EG18353A (de)
ES (1) ES2022319B3 (de)
FI (1) FI94636C (de)
GR (1) GR3001863T3 (de)
HU (1) HU206618B (de)
IE (1) IE59450B1 (de)
IL (1) IL81261A (de)
NO (1) NO171411C (de)
NZ (1) NZ218970A (de)
PH (2) PH22231A (de)
PL (1) PL148082B1 (de)
PT (1) PT84107B (de)
WO (1) WO1987004344A1 (de)
YU (1) YU46042B (de)
ZA (1) ZA87309B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84806B (pt) * 1986-05-03 1989-12-29 Beecham Group Plc Processo para a preparacao de benzopiranos
AU2440599A (en) * 1998-02-25 1999-09-15 Shionogi & Co., Ltd. Therapeutic agent for complication of diabetes
AT502844B1 (de) * 2005-12-12 2007-08-15 Fronius Int Gmbh Schweissbrenner und endstück sowie kontaktrohr für einen schweissbrenner
CN102171200B (zh) * 2008-10-02 2015-09-30 坎布雷卡尔斯库加公司 用于制备二酮类和药物的方法
CN105924425B (zh) * 2016-04-29 2018-06-05 浙江师范大学 一种制备二氢硫色满衍生物的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3359161A (en) * 1963-08-29 1967-12-19 Kefalas As Thiaxanthenols, process of producing and anti-tussive compositions thereof
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
US4210663A (en) * 1978-11-08 1980-07-01 Pfizer Inc. Halogen substituted benzopyran- and benzothiopyran-4-carboxylic acids
US4286098A (en) * 1980-03-28 1981-08-25 Pfizer Inc. Process for the preparation of chiral hydantoins
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
US4305955A (en) * 1980-10-21 1981-12-15 Pfizer Inc. Carboxylic acid therapeutic agents
ATE11781T1 (de) * 1981-05-13 1985-02-15 Imperial Chemical Industries Plc Pharmazeutische zubereitungen, die spirosuccinimidderivate enthalten.
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds

Also Published As

Publication number Publication date
EG18353A (en) 1993-02-28
DK21687D0 (da) 1987-01-16
JPH0586952B2 (de) 1993-12-14
FI873843A (fi) 1987-09-04
YU46042B (sh) 1992-12-21
PH24703A (en) 1990-10-01
JPS62169775A (ja) 1987-07-25
KR890004104B1 (ko) 1989-10-20
HUT48230A (en) 1989-05-29
IE59450B1 (en) 1994-02-23
ATE62237T1 (de) 1991-04-15
ZA87309B (de) 1988-07-18
NO171411B (no) 1992-11-30
DK21687A (da) 1987-07-18
PL148082B1 (en) 1989-09-30
PT84107A (en) 1987-02-01
PH22231A (en) 1988-07-01
PT84107B (pt) 1989-07-31
EP0230379A3 (en) 1988-10-05
AU574001B2 (en) 1988-06-23
EP0230379B1 (de) 1991-04-03
CA1283119C (en) 1991-04-16
NO171411C (no) 1993-03-10
WO1987004344A1 (en) 1987-07-30
NO873854D0 (no) 1987-09-15
AU6764187A (en) 1987-07-30
CN87100191A (zh) 1987-09-09
FI94636B (fi) 1995-06-30
NZ218970A (en) 1988-11-29
IE870131L (en) 1987-07-17
KR870007149A (ko) 1987-08-17
IL81261A (en) 1992-05-25
IL81261A0 (en) 1987-08-31
EP0230379A2 (de) 1987-07-29
NO873854L (no) 1987-09-15
FI873843A0 (fi) 1987-09-04
DD266735A5 (de) 1989-04-12
YU5787A (en) 1988-04-30
PL263678A1 (en) 1988-04-14
HU206618B (en) 1992-12-28
ES2022319B3 (es) 1991-12-01
GR3001863T3 (en) 1992-11-23
FI94636C (fi) 1995-10-10
CN1015545B (zh) 1992-02-19
US4853410A (en) 1989-08-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee