DE68904462T2 - 4-chinolincarbonsaeure-derivate, brauchbar zur behandlung von haut- und muco-epithelial-gewebekrankheiten. - Google Patents

4-chinolincarbonsaeure-derivate, brauchbar zur behandlung von haut- und muco-epithelial-gewebekrankheiten.

Info

Publication number
DE68904462T2
DE68904462T2 DE8989107098T DE68904462T DE68904462T2 DE 68904462 T2 DE68904462 T2 DE 68904462T2 DE 8989107098 T DE8989107098 T DE 8989107098T DE 68904462 T DE68904462 T DE 68904462T DE 68904462 T2 DE68904462 T2 DE 68904462T2
Authority
DE
Germany
Prior art keywords
muco
useable
acid derivatives
carbonic acid
epithelial tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989107098T
Other languages
English (en)
Other versions
DE68904462D1 (de
Inventor
Neil Richard Ackerman
Richard Russell Harris
Scott Edward Loveless
Russell Howard Neubauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
DuPont Merck Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DuPont Merck Pharmaceutical Co filed Critical DuPont Merck Pharmaceutical Co
Application granted granted Critical
Publication of DE68904462D1 publication Critical patent/DE68904462D1/de
Publication of DE68904462T2 publication Critical patent/DE68904462T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE8989107098T 1988-04-26 1989-04-20 4-chinolincarbonsaeure-derivate, brauchbar zur behandlung von haut- und muco-epithelial-gewebekrankheiten. Expired - Fee Related DE68904462T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/186,242 US4861783A (en) 1988-04-26 1988-04-26 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases

Publications (2)

Publication Number Publication Date
DE68904462D1 DE68904462D1 (de) 1993-03-04
DE68904462T2 true DE68904462T2 (de) 1993-05-13

Family

ID=22684175

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989107098T Expired - Fee Related DE68904462T2 (de) 1988-04-26 1989-04-20 4-chinolincarbonsaeure-derivate, brauchbar zur behandlung von haut- und muco-epithelial-gewebekrankheiten.

Country Status (16)

Country Link
US (1) US4861783A (de)
EP (1) EP0339484B1 (de)
JP (1) JP2650756B2 (de)
KR (1) KR0124817B1 (de)
AT (1) ATE84716T1 (de)
AU (1) AU610469B2 (de)
CA (1) CA1336263C (de)
DE (1) DE68904462T2 (de)
DK (1) DK199789A (de)
ES (1) ES2053856T3 (de)
IE (1) IE64285B1 (de)
IL (1) IL90056A (de)
MY (1) MY104006A (de)
NZ (1) NZ228894A (de)
PT (1) PT90362B (de)
ZA (1) ZA893086B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5102883A (en) * 1989-10-31 1992-04-07 Du Pont Merck Pharmaceutical Company Pyrimidine biosynthesis inhibitors useful as immunosuppressive agents
US5204329A (en) * 1990-06-11 1993-04-20 Du Pont Merck Pharmaceutical Company Treatment of organ transplantation rejection
US5135934A (en) * 1990-07-06 1992-08-04 Du Pont Merck Pharmaceutical Company 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
US5281196A (en) * 1992-05-22 1994-01-25 Sultenfuss Thomas J Skin treatment composition and method of use
US5409886A (en) * 1993-02-18 1995-04-25 Mitsui Toatsu Chemicals, Incorporated 3-pyrroline-2-one derivatives and herbicidal compositions containing same
US5578609A (en) * 1994-03-25 1996-11-26 The Dupont Merck Pharmaceutical Company 2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
US6376670B1 (en) 1997-06-19 2002-04-23 Sepracor Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6207679B1 (en) 1997-06-19 2001-03-27 Sepracor, Inc. Antimicrobial agents uses and compositions related thereto
AU757059B2 (en) 1997-06-19 2003-01-30 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
JP4318087B2 (ja) * 2004-12-13 2009-08-19 小野薬品工業株式会社 アミノカルボン酸誘導体およびその医薬用途
WO2014070769A1 (en) 2012-10-29 2014-05-08 The University Of North Carolina At Chapel Hill Methods and compositions for treating mucosal tissue disorders
EA201691057A1 (ru) 2013-11-22 2016-10-31 Джензим Корпорейшн Новые способы лечения нейродегенеративных заболеваний
KR20190097022A (ko) 2016-11-17 2019-08-20 레노비온, 아이엔씨. 글루타티온 조성물에 의한 호흡기 질환 및 감염 치료
EP3710036A4 (de) 2017-11-17 2021-07-21 Renovion, Inc. Stabile ascorbinsäurezusammensetzungen und verfahren zu ihrer verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4181725A (en) * 1977-05-02 1980-01-01 The Regents Of The University Of Michigan Method for alleviating psoriasis
AU583793B2 (en) * 1983-07-22 1989-05-11 Du Pont Pharmaceuticals Company Phenylquinolinecarboxylic acids and derivatives as antitumor agents
US4680299A (en) * 1984-04-30 1987-07-14 E.I. Du Pont De Nemours And Company 2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof
US4889862A (en) * 1986-08-28 1989-12-26 E. I. Du Pont De Nemours And Company Freeze-dried pharmaceutical compositions of phenylquinoline carboxylic acids

Also Published As

Publication number Publication date
DK199789A (da) 1989-10-27
JP2650756B2 (ja) 1997-09-03
IL90056A (en) 1993-04-04
MY104006A (en) 1993-10-30
EP0339484B1 (de) 1993-01-20
AU610469B2 (en) 1991-05-16
US4861783A (en) 1989-08-29
PT90362A (pt) 1989-11-10
EP0339484A1 (de) 1989-11-02
ATE84716T1 (de) 1993-02-15
AU3331889A (en) 1989-11-02
IL90056A0 (en) 1989-12-15
JPH0272163A (ja) 1990-03-12
ZA893086B (en) 1990-12-28
ES2053856T3 (es) 1994-08-01
PT90362B (pt) 1994-07-29
CA1336263C (en) 1995-07-11
IE64285B1 (en) 1995-07-26
DE68904462D1 (de) 1993-03-04
KR900016135A (ko) 1990-11-12
IE891329L (en) 1989-10-26
NZ228894A (en) 1992-02-25
KR0124817B1 (ko) 1997-11-25
DK199789D0 (da) 1989-04-25

Similar Documents

Publication Publication Date Title
DE1300150T1 (de) Prostaglandin-Derivate zur Behandlung von Glaukom oder Augenüberdruck
DE68904462T2 (de) 4-chinolincarbonsaeure-derivate, brauchbar zur behandlung von haut- und muco-epithelial-gewebekrankheiten.
DE3856594D1 (de) Mittel zur behandlung der alzheimer-krankheit
NO890259D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive etylfenoksyacetamider.
DE69631478D1 (de) Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen
DE3587741D1 (de) Behandlung von Hautkrankheiten.
ES2110414T3 (es) Derivados de sacarina utiles como inhibidores de enzimas proteoliticas y su preparacion.
ATE106736T1 (de) Verwendung von dimethylpolysiloxan zur behandlung von erkrankungen des gastrointestinaltraktes.
ATE148628T1 (de) 5-methylisoxazol-4-carbonsäure-anilide und 2- hydroxyethyliden-cyanoessigsäure-anilide zur behandlung von augenkrankheiten
IT8721115A0 (it) Fitopreparato per la cura di affezioni cutanee.
GR3006674T3 (de)
ATE183088T1 (de) Arzneimittel zur behandlung von hauterkrankungen
NO910033L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 2-hydroksy-3-fenoksypropylaminoforbindelser.
DE3687233T2 (de) Pharmazeutische zusammensetzungen zur behandlung von hautkrankheiten.
DE59410340D1 (de) Verwendung von Bradykinin-Antagonisten zur Behandlung von Viruserkrankungen
DE3668338D1 (de) Kontinuierliche behandlung von spannungslosem gewebe.
ATE78160T1 (de) Verwendung von ''naftidrofuryl'' zur behandlung von neuropathien.
DE69022027D1 (de) 2-Alkyl-3-benzoylbenzofurane zur Behandlung von Herzarrhythmia.
DE68906028D1 (de) Verwendung von acetyl-d-carnitin zur therapeutischen behandlung von glaukom.
DE68914886D1 (de) Mittel zur Behandlung von Raynaud's Krankheit.
ATE88090T1 (de) Verwendung von acetyl-d-carnitin zur therapeutischen behandlung von glaukom.
IT8919216A0 (it) Dispositivo per la cura chirurgica dell'astigmatismo.
NO900616L (no) Fremgangsmaate for fraksjonering av avlinger i industrieltraamateriale.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8327 Change in the person/name/address of the patent owner

Owner name: DU PONT PHARMACEUTICALS CO., WILMINGTON, DEL., US