IL78510A - 1-(o-fluorophenylalkyl)-1,2,3-triazol-4-ylcarboxamides,their preparation and pharmaceutical compositions containing them - Google Patents

1-(o-fluorophenylalkyl)-1,2,3-triazol-4-ylcarboxamides,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL78510A
IL78510A IL78510A IL7851086A IL78510A IL 78510 A IL78510 A IL 78510A IL 78510 A IL78510 A IL 78510A IL 7851086 A IL7851086 A IL 7851086A IL 78510 A IL78510 A IL 78510A
Authority
IL
Israel
Prior art keywords
fluorophenylalkyl
ylcarboxamides
triazol
preparation
pharmaceutical compositions
Prior art date
Application number
IL78510A
Other languages
English (en)
Other versions
IL78510A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL78510A0 publication Critical patent/IL78510A0/xx
Publication of IL78510A publication Critical patent/IL78510A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL78510A 1985-04-18 1986-04-15 1-(o-fluorophenylalkyl)-1,2,3-triazol-4-ylcarboxamides,their preparation and pharmaceutical compositions containing them IL78510A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18

Publications (2)

Publication Number Publication Date
IL78510A0 IL78510A0 (en) 1986-08-31
IL78510A true IL78510A (en) 1992-05-25

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78510A IL78510A (en) 1985-04-18 1986-04-15 1-(o-fluorophenylalkyl)-1,2,3-triazol-4-ylcarboxamides,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
EP (1) EP0199262B1 (es)
JP (1) JPS61243068A (es)
KR (1) KR900008810B1 (es)
AU (1) AU599024B2 (es)
CA (1) CA1272201A (es)
CY (1) CY1751A (es)
DD (1) DD245874A5 (es)
DE (1) DE3677626D1 (es)
DK (1) DK169720B1 (es)
ES (2) ES8800176A1 (es)
FI (1) FI93544C (es)
GR (1) GR861004B (es)
HK (1) HK1494A (es)
HU (1) HU203327B (es)
IE (1) IE58472B1 (es)
IL (1) IL78510A (es)
MX (1) MX9203628A (es)
NO (1) NO164295C (es)
NZ (1) NZ215871A (es)
PH (1) PH22568A (es)
PT (1) PT82400B (es)
ZA (1) ZA862873B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
WO1997040025A1 (en) * 1996-04-19 1997-10-30 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
SK283990B6 (sk) * 1996-07-11 2004-07-07 Novartis Ag Spôsob prípravy 1-substituovaných 4-kyano-1,2,3-triazolov, 4-kyano-1-(2,6-difluórbenzyl)-1H-1,2,3-triazol
TW403740B (en) 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (it) * 2009-03-23 2012-04-20 Dipharma Francis Srl Metodo per la preparazione di rufinamide
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
US8884026B2 (en) * 2010-04-30 2014-11-11 Laboratorios Lesvi, S.L. Process for preparing rufinamide intermediate
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
WO2014120994A1 (en) * 2013-01-31 2014-08-07 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
US12023322B2 (en) 2015-12-11 2024-07-02 Aarhus Universitet Rufinamide for use in the treatment of myotonia
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (fi) * 1982-12-23 1984-06-24 Ciba Geigy Ag Foerfarande foer framstaellning av nya aralkyltriazolfoereningar.

Also Published As

Publication number Publication date
DK169720B1 (da) 1995-01-23
ES554024A0 (es) 1987-10-16
JPS61243068A (ja) 1986-10-29
EP0199262B1 (de) 1991-02-27
AU5631986A (en) 1986-10-23
ZA862873B (en) 1986-12-30
HUT40792A (en) 1987-02-27
ES557641A0 (es) 1988-07-01
CA1272201A (en) 1990-07-31
PT82400A (en) 1986-05-01
IL78510A0 (en) 1986-08-31
ES8800176A1 (es) 1987-10-16
AU599024B2 (en) 1990-07-12
GR861004B (en) 1986-08-12
IE861015L (en) 1986-10-18
NZ215871A (en) 1989-01-27
DK175686A (da) 1986-10-19
FI93544C (fi) 1995-04-25
EP0199262A2 (de) 1986-10-29
DD245874A5 (de) 1987-05-20
IE58472B1 (en) 1993-09-22
NO164295C (no) 1990-09-19
PH22568A (en) 1988-10-17
NO861486L (no) 1986-10-20
DK175686D0 (da) 1986-04-17
FI93544B (fi) 1995-01-13
PT82400B (pt) 1988-08-17
MX9203628A (es) 1992-09-01
HU203327B (en) 1991-07-29
CY1751A (en) 1994-06-03
FI861573A (fi) 1986-10-19
DE3677626D1 (de) 1991-04-04
EP0199262A3 (en) 1987-08-26
ES8802501A1 (es) 1988-07-01
KR860008152A (ko) 1986-11-12
FI861573A0 (fi) 1986-04-14
HK1494A (en) 1994-01-14
KR900008810B1 (ko) 1990-11-30
NO164295B (no) 1990-06-11
JPH0564949B2 (es) 1993-09-16

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Legal Events

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