IL78044A - Expression in a microorganism of hybrid polypeptides containing the growth hormone releasing factor sequence preceded by a tryptophan amino acid - Google Patents
Expression in a microorganism of hybrid polypeptides containing the growth hormone releasing factor sequence preceded by a tryptophan amino acidInfo
- Publication number
- IL78044A IL78044A IL78044A IL7804486A IL78044A IL 78044 A IL78044 A IL 78044A IL 78044 A IL78044 A IL 78044A IL 7804486 A IL7804486 A IL 7804486A IL 78044 A IL78044 A IL 78044A
- Authority
- IL
- Israel
- Prior art keywords
- microorganism
- expression
- amino acid
- growth hormone
- hormone releasing
- Prior art date
Links
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 title 1
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 title 1
- 101710142969 Somatoliberin Proteins 0.000 title 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- -1 tryptophan amino acid Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8547856A IT1234977B (it) | 1985-03-22 | 1985-03-22 | Espressione in e. coli polipeptidi ibridi contenenti la sequenza del fattore di rilascio dell'ormone della crescita |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL78044A0 IL78044A0 (en) | 1986-07-31 |
| IL78044A true IL78044A (en) | 1991-07-18 |
Family
ID=11262958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL78044A IL78044A (en) | 1985-03-22 | 1986-03-05 | Expression in a microorganism of hybrid polypeptides containing the growth hormone releasing factor sequence preceded by a tryptophan amino acid |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0199018B1 (it) |
| JP (3) | JPH0779701B2 (it) |
| AR (1) | AR242056A1 (it) |
| AT (1) | ATE84548T1 (it) |
| AU (1) | AU600891B2 (it) |
| DE (1) | DE3687470T2 (it) |
| DK (1) | DK122486A (it) |
| ES (1) | ES8800722A1 (it) |
| FI (1) | FI93125C (it) |
| IL (1) | IL78044A (it) |
| IT (1) | IT1234977B (it) |
| NO (1) | NO175318C (it) |
| ZA (1) | ZA861644B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1200162B (it) * | 1985-12-18 | 1989-01-05 | Serono Ist Farm | Protezione della metionina in una catena polipeptidica dalla ossidazione irreversibile |
| US4828988A (en) * | 1986-05-15 | 1989-05-09 | Smith Kline - Rit | Hybrid polypeptides comprising somatocrinine and alpha1 -antitrypsin, method for their production from bacterial clones and use thereof for the production of somatocrinine |
| US5565606A (en) * | 1986-10-21 | 1996-10-15 | Hoechst Aktiengesellschaft | Synthesis of peptide aminoalkylamides and peptide hydrazides by the solid-phase method |
| NZ237857A (en) | 1990-04-24 | 1992-05-26 | Lilly Co Eli | Polypeptide compounds with growth hormone releasing factor activity |
| US5512459A (en) * | 1993-07-20 | 1996-04-30 | Bionebraska, Inc. | Enzymatic method for modification or recombinant polypeptides |
| DE4435960C2 (de) * | 1994-10-07 | 1998-05-20 | Goodwell Int Ltd | Snowboardbindung |
| US6759393B1 (en) | 1999-04-12 | 2004-07-06 | Pfizer Inc. | Growth hormone and growth hormone releasing hormone compositions |
| JP2000350590A (ja) * | 1999-04-12 | 2000-12-19 | Pfizer Prod Inc | 成長ホルモン及び成長ホルモン放出ホルモン組成物 |
| EP1205551A1 (en) * | 2000-11-09 | 2002-05-15 | Pfizer Products Inc. | Growth hormone and growth hormone releasing hormone compositions |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA811368B (en) * | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
| JPS58201796A (ja) * | 1982-05-19 | 1983-11-24 | Takeda Chem Ind Ltd | 組換えｄｎａおよびその用途 |
| GB2102006B (en) * | 1981-06-16 | 1984-11-28 | Takeda Chemical Industries Ltd | Deoxyribonucleic acids, their production and use |
| US4499188A (en) * | 1982-05-05 | 1985-02-12 | Cetus Corporation | Bacterial production of heterologous polypeptides under the control of a repressible promoter-operator |
| EP0108387B1 (en) * | 1982-11-04 | 1990-05-16 | F. Hoffmann-La Roche Ag | Preparation of recombinant growth releasing factors |
| JPS59154989A (ja) * | 1983-02-23 | 1984-09-04 | Mitsubishi Chem Ind Ltd | プラスミド |
| JPS59227899A (ja) * | 1983-05-25 | 1984-12-21 | チロン・コ−ポレイシヨン | 成長ホルモン放出因子の製造方法 |
| DE3327007A1 (de) * | 1983-07-27 | 1985-02-07 | Hoechst Ag, 6230 Frankfurt | Herstellung von polypeptiden mit einem saeureamid-carboxyterminus |
| IT1198443B (it) * | 1984-03-30 | 1988-12-21 | Serono Ist Farm | Espressione genetica di polipeptidi ibridi contenenti la sequenza della somatostatina |
| FR2587359B1 (fr) * | 1985-05-28 | 1987-12-24 | Sanofi Sa | Derives non amides de la somatocrinine et procede de preparation par genie genetique |
-
1985
- 1985-03-22 IT IT8547856A patent/IT1234977B/it active
-
1986
- 1986-02-25 DE DE8686102447T patent/DE3687470T2/de not_active Expired - Fee Related
- 1986-02-25 EP EP86102447A patent/EP0199018B1/en not_active Expired - Lifetime
- 1986-02-25 AT AT86102447T patent/ATE84548T1/de not_active IP Right Cessation
- 1986-03-05 IL IL78044A patent/IL78044A/xx not_active IP Right Cessation
- 1986-03-05 ZA ZA861644A patent/ZA861644B/xx unknown
- 1986-03-17 DK DK122486A patent/DK122486A/da not_active Application Discontinuation
- 1986-03-18 JP JP61058448A patent/JPH0779701B2/ja not_active Expired - Lifetime
- 1986-03-18 AU AU54843/86A patent/AU600891B2/en not_active Ceased
- 1986-03-19 AR AR86303426A patent/AR242056A1/es active
- 1986-03-21 FI FI861217A patent/FI93125C/fi not_active IP Right Cessation
- 1986-03-21 ES ES553274A patent/ES8800722A1/es not_active Expired
- 1986-03-21 NO NO861142A patent/NO175318C/no unknown
-
1994
- 1994-02-28 JP JP6029632A patent/JPH0816120B2/ja not_active Expired - Lifetime
-
1995
- 1995-06-09 JP JP7143597A patent/JP2537029B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES553274A0 (es) | 1987-12-01 |
| JPH07316197A (ja) | 1995-12-05 |
| IL78044A0 (en) | 1986-07-31 |
| DK122486A (da) | 1986-09-23 |
| FI861217A0 (fi) | 1986-03-21 |
| FI93125C (fi) | 1995-02-27 |
| FI861217L (fi) | 1986-09-23 |
| JPH0710900A (ja) | 1995-01-13 |
| NO175318B (no) | 1994-06-20 |
| IT8547856A0 (it) | 1985-03-22 |
| JPH0816120B2 (ja) | 1996-02-21 |
| NO175318C (no) | 1994-09-28 |
| DE3687470D1 (de) | 1993-02-25 |
| ZA861644B (en) | 1986-10-29 |
| AU5484386A (en) | 1986-09-25 |
| DE3687470T2 (de) | 1993-05-19 |
| EP0199018A2 (en) | 1986-10-29 |
| JP2537029B2 (ja) | 1996-09-25 |
| FI93125B (fi) | 1994-11-15 |
| DK122486D0 (da) | 1986-03-17 |
| JPH0779701B2 (ja) | 1995-08-30 |
| AR242056A1 (es) | 1993-02-26 |
| EP0199018A3 (en) | 1987-07-22 |
| EP0199018B1 (en) | 1993-01-13 |
| ES8800722A1 (es) | 1987-12-01 |
| ATE84548T1 (de) | 1993-01-15 |
| AU600891B2 (en) | 1990-08-30 |
| NO861142L (no) | 1986-09-23 |
| IT1234977B (it) | 1992-06-09 |
| JPS61274686A (ja) | 1986-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH | Patent void |