IL76616A - Process for the preparation of fluorinated pyridine derivatives and novel intermediates therefor - Google Patents
Process for the preparation of fluorinated pyridine derivatives and novel intermediates thereforInfo
- Publication number
- IL76616A IL76616A IL76616A IL7661685A IL76616A IL 76616 A IL76616 A IL 76616A IL 76616 A IL76616 A IL 76616A IL 7661685 A IL7661685 A IL 7661685A IL 76616 A IL76616 A IL 76616A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- preparation
- image
- pyridine derivatives
- novel intermediates
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 2
- 150000003222 pyridines Chemical class 0.000 title 1
- OGVLEPMNNPZAPS-UHFFFAOYSA-N 2,3-difluoropyridine Chemical class FC1=CC=CN=C1F OGVLEPMNNPZAPS-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 125000001246 bromo group Chemical group Br* 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Chemical group 0.000 abstract 2
- QFBLCGZSGBBAJW-UHFFFAOYSA-N 2-[4-(3-fluoropyridin-2-yl)oxyphenoxy]propanoic acid Chemical class C1=CC(OC(C)C(O)=O)=CC=C1OC1=NC=CC=C1F QFBLCGZSGBBAJW-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000012025 fluorinating agent Substances 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C07D213/643—2-Phenoxypyridines; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH485584 | 1984-10-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL76616A0 IL76616A0 (en) | 1986-02-28 |
| IL76616A true IL76616A (en) | 1989-06-30 |
Family
ID=4283718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL76616A IL76616A (en) | 1984-10-10 | 1985-10-09 | Process for the preparation of fluorinated pyridine derivatives and novel intermediates therefor |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4831148A (fr) |
| EP (1) | EP0178260B1 (fr) |
| JP (2) | JPS6191171A (fr) |
| AT (1) | ATE52775T1 (fr) |
| CA (1) | CA1226865A (fr) |
| DE (1) | DE3577704D1 (fr) |
| IL (1) | IL76616A (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3545570A1 (de) * | 1985-12-21 | 1987-06-25 | Hoechst Ag | Neue pyridin-derivate und deren n-oxide, verfahren zu ihrer herstellung und ihre verwendung als zwischenprodukte |
| US4999432A (en) * | 1989-08-28 | 1991-03-12 | Dowelanco | Fluorination with hydrogen fluoride |
| US5027520A (en) * | 1990-08-15 | 1991-07-02 | Finnegan Danny E | Farrier's instrument |
| US5274100A (en) * | 1990-10-23 | 1993-12-28 | Ciba-Geigy Corporation | Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids |
| DE4111215A1 (de) * | 1991-04-06 | 1992-10-08 | Bayer Ag | Verfahren zur herstellung von 2-chlorpyridinen |
| CN102532008A (zh) * | 2012-01-12 | 2012-07-04 | 南京红太阳生物化学有限责任公司 | 一种合成2，5-二氯-3-氟吡啶的新方法 |
| WO2014012811A1 (fr) * | 2012-07-18 | 2014-01-23 | Basf Se | Procédé pour la fabrication de composés aromatiques fluorés |
| CN106279003A (zh) * | 2016-07-13 | 2017-01-04 | 南京红太阳生物化学有限责任公司 | 一种2‑氯‑5‑甲基吡啶的制备方法 |
| CN115108971A (zh) * | 2022-06-30 | 2022-09-27 | 杭州凯氟科技有限公司 | 一种2,3-二氟-5-氯吡啶的制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2563796A (en) * | 1948-05-26 | 1951-08-07 | Harshaw Chem Corp | Manufacture of aromatic diazonium fluorides and corresponding aromatic fluorides |
| GB1344636A (en) * | 1970-10-30 | 1974-01-23 | Ici Ltd | Manufacture of halogenated pyridine derivatives |
| US3703521A (en) * | 1971-03-22 | 1972-11-21 | Olin Corp | Method for the preparation of stable 4-fluoropyridine salts |
| JPS5314057B2 (fr) * | 1972-12-15 | 1978-05-15 | ||
| GB1415825A (en) * | 1974-02-26 | 1975-11-26 | Olin Corp | Method for the preparation of difluoropyridines |
| DE2409379C3 (de) * | 1974-02-27 | 1980-11-27 | Olin Corp., New Haven, Conn. (V.St.A.) | Verfahren zur Herstellung von Difluorpyridinen und substituierten Difluorpyridinen |
| US4096196A (en) * | 1975-10-31 | 1978-06-20 | Olin Corporation | Diazotization-fluorination in a medium of hydrogen fluoride containing tertiary amine compounds |
| GB1534841A (en) * | 1976-07-23 | 1978-12-06 | Olin Corp | Preparation of fluorobenzenes and fluoropyridines |
| US4071521A (en) * | 1976-08-23 | 1978-01-31 | The Dow Chemical Company | Process for making 2,6-difluoro pyridine |
| US4031100A (en) * | 1976-08-23 | 1977-06-21 | The Dow Chemical Company | Process for making 2,6-difluoropyridine |
| JPS5368783A (en) * | 1976-12-01 | 1978-06-19 | Ishihara Sangyo Kaisha Ltd | Preparation of 2,3,5-trichloropyridine |
| GB2039473B (en) * | 1979-01-11 | 1983-05-05 | Dow Chemical Co | Reaction of a chlorinated pyridine with an alkali metal fluoride |
| GB2053189A (en) * | 1979-07-12 | 1981-02-04 | Pfizer Ltd | Antifungal pyridine-2-thiones |
| US4505743A (en) * | 1981-12-31 | 1985-03-19 | Ciba-Geigy Corporation | α-[4-(3-Fluoro-5'-halopyridyl-2'-oxy)-phenoxy]-propionic acid derivatives having herbicidal activity |
| JPS58219163A (ja) * | 1982-06-16 | 1983-12-20 | Dainippon Ink & Chem Inc | フルオロヘテロ環化合物の製法 |
| IL68822A (en) * | 1982-06-18 | 1990-07-12 | Dow Chemical Co | Pyridyl(oxy/thio)phenoxy compounds,herbicidal compositions and methods of using them |
| JPS59283A (ja) * | 1982-06-25 | 1984-01-05 | Hitachi Ltd | スキユ−歪補正回路 |
| US4480102A (en) * | 1982-07-23 | 1984-10-30 | The Dow Chemical Company | 2,3-Difluoro-5-(trifluoromethyl)pyridine and methods of making and using the same |
| DE3234451A1 (de) * | 1982-09-17 | 1984-03-22 | Hoechst Ag, 6230 Frankfurt | Neue pyridylharnstoffe, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung als herbizide |
-
1985
- 1985-10-04 US US06/784,017 patent/US4831148A/en not_active Expired - Lifetime
- 1985-10-04 EP EP85810455A patent/EP0178260B1/fr not_active Expired - Lifetime
- 1985-10-04 DE DE8585810455T patent/DE3577704D1/de not_active Expired - Lifetime
- 1985-10-04 AT AT85810455T patent/ATE52775T1/de not_active IP Right Cessation
- 1985-10-07 JP JP60222018A patent/JPS6191171A/ja active Pending
- 1985-10-08 CA CA000492475A patent/CA1226865A/fr not_active Expired
- 1985-10-09 IL IL76616A patent/IL76616A/xx unknown
-
1994
- 1994-09-07 JP JP23857794A patent/JP2500229B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2500229B2 (ja) | 1996-05-29 |
| EP0178260B1 (fr) | 1990-05-16 |
| JPS6191171A (ja) | 1986-05-09 |
| DE3577704D1 (de) | 1990-06-21 |
| EP0178260A3 (en) | 1987-01-07 |
| EP0178260A2 (fr) | 1986-04-16 |
| IL76616A0 (en) | 1986-02-28 |
| US4831148A (en) | 1989-05-16 |
| CA1226865A (fr) | 1987-09-15 |
| ATE52775T1 (de) | 1990-06-15 |
| JPH07165718A (ja) | 1995-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC | Change of name of proprietor(s) | ||
| KB | Patent renewed | ||
| KB | Patent renewed |