IL75135A - Hexa-and tetrahydrobenzo(thio)pyrano(3,4-b)pyridines,their preparation and pharmaceutical compositions containing them - Google Patents

Hexa-and tetrahydrobenzo(thio)pyrano(3,4-b)pyridines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL75135A
IL75135A IL75135A IL7513585A IL75135A IL 75135 A IL75135 A IL 75135A IL 75135 A IL75135 A IL 75135A IL 7513585 A IL7513585 A IL 7513585A IL 75135 A IL75135 A IL 75135A
Authority
IL
Israel
Prior art keywords
tetrahydrobenzo
pyrano
pyridines
hexa
thio
Prior art date
Application number
IL75135A
Other languages
English (en)
Other versions
IL75135A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL75135A0 publication Critical patent/IL75135A0/xx
Publication of IL75135A publication Critical patent/IL75135A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
IL75135A 1984-05-10 1985-05-08 Hexa-and tetrahydrobenzo(thio)pyrano(3,4-b)pyridines,their preparation and pharmaceutical compositions containing them IL75135A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60903784A 1984-05-10 1984-05-10

Publications (2)

Publication Number Publication Date
IL75135A0 IL75135A0 (en) 1985-09-29
IL75135A true IL75135A (en) 1989-07-31

Family

ID=24439108

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75135A IL75135A (en) 1984-05-10 1985-05-08 Hexa-and tetrahydrobenzo(thio)pyrano(3,4-b)pyridines,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US4604397A (fr)
EP (1) EP0161218B1 (fr)
JP (1) JPS60243090A (fr)
AR (1) AR243526A1 (fr)
AT (1) ATE64735T1 (fr)
AU (1) AU592308B2 (fr)
CA (1) CA1298582C (fr)
DD (1) DD235872A5 (fr)
DE (1) DE3583307D1 (fr)
DK (1) DK168571B1 (fr)
ES (5) ES8706687A1 (fr)
FI (1) FI83652C (fr)
GR (1) GR851116B (fr)
HU (1) HU199476B (fr)
IE (1) IE57978B1 (fr)
IL (1) IL75135A (fr)
NO (1) NO162860C (fr)
NZ (1) NZ212031A (fr)
PT (1) PT80415B (fr)
ZA (1) ZA853507B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
US4666916A (en) * 1985-11-08 1987-05-19 Ciba-Geigy Corporation Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents
US4792548A (en) * 1986-05-21 1988-12-20 Warner-Lambert Company Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
FR2619112B1 (fr) * 1987-08-07 1989-11-17 Synthelabo Derives de (piperidinyl-4)methyl-2 benzo(b)furo(2,3-c) pyridines, leur preparation et leur application en therapeutique
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
US5962463A (en) * 1992-10-09 1999-10-05 Massachusetts Institute Of Technology Methods of stimulating non-amyloidogenic processing of the amyloid precursor protein
FR2721027B1 (fr) * 1994-06-08 1996-07-19 Adir Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant.
FR2741074B1 (fr) 1995-11-09 1997-12-19 Adir Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
DE60039132D1 (de) * 1999-04-06 2008-07-17 Sepracor Inc O-Desmethylvenlafaxin-Succinat
WO2005032485A2 (fr) * 2003-10-03 2005-04-14 Psychogenics, Inc. Composes et procedes pour le traitement de l'hyperactivite avec deficit de l'attention
MX2008000249A (es) * 2005-07-06 2008-03-18 Sepracor Inc Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos.
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143819A (fr) * 1965-09-27
US3514464A (en) * 1967-05-29 1970-05-26 Little Inc A 5-oxo-1,2,3,4-tetrahydro-5h-(1)benzopyrano(3,4-c)pyridines
US3689497A (en) * 1971-03-09 1972-09-05 Warner Lambert Co Substituted benzopyrano (3,4-b) pyridines and process for their preparation
US3915996A (en) * 1972-10-16 1975-10-28 Abbott Lab Process for making benzopyrans
US4025630A (en) * 1973-09-19 1977-05-24 Abbott Laboratories Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication
US4292316A (en) * 1978-10-02 1981-09-29 Abbott Laboratories Antiglaucoma agents
US4210758A (en) * 1979-03-21 1980-07-01 Warner-Lambert Company 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-2-carboxamides
US4198511A (en) * 1979-03-21 1980-04-15 Warner-Lambert Company 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-3-carboxamides and process thereof
JPS5746903A (en) * 1980-09-05 1982-03-17 Mitsubishi Chem Ind Ltd Agricultural and gardening fungicide
NL8005754A (nl) * 1980-10-18 1982-05-17 Akzo Nv Benzo 4,5 pyrano 2,3-c pyrrool derivaten.
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
US4540691A (en) * 1984-04-13 1985-09-10 Nelson Research & Development Co. Dopamine agonists and use thereof
US4666916A (en) * 1985-11-08 1987-05-19 Ciba-Geigy Corporation Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents

Also Published As

Publication number Publication date
FI851802A0 (fi) 1985-05-08
ATE64735T1 (de) 1991-07-15
FI83652B (fi) 1991-04-30
HUT37939A (en) 1986-03-28
AU592308B2 (en) 1990-01-11
DE3583307D1 (en) 1991-08-01
US4604397A (en) 1986-08-05
CA1298582C (fr) 1992-04-07
DK205285A (da) 1985-11-11
NO162860C (no) 1990-02-28
EP0161218B1 (fr) 1991-06-26
ES555529A0 (es) 1988-01-01
HU199476B (en) 1990-02-28
IE851155L (en) 1985-11-10
GR851116B (fr) 1985-11-25
PT80415A (en) 1985-06-01
JPH0443917B2 (fr) 1992-07-20
FI83652C (fi) 1991-08-12
NO851846L (no) 1985-11-11
PT80415B (en) 1987-04-16
ES555530A0 (es) 1988-01-01
ES8801280A1 (es) 1988-01-01
AU4224885A (en) 1985-11-14
IE57978B1 (en) 1993-06-02
IL75135A0 (en) 1985-09-29
AR243526A1 (es) 1993-08-31
ES8801279A1 (es) 1988-01-01
ES542929A0 (es) 1987-07-01
ES8801282A1 (es) 1988-01-01
EP0161218A2 (fr) 1985-11-13
ES8706687A1 (es) 1987-07-01
ZA853507B (en) 1985-12-24
ES555528A0 (es) 1988-01-01
JPS60243090A (ja) 1985-12-03
DD235872A5 (de) 1986-05-21
DK168571B1 (da) 1994-04-25
ES555527A0 (es) 1988-01-01
EP0161218A3 (en) 1987-03-04
DK205285D0 (da) 1985-05-09
ES8801281A1 (es) 1988-01-01
NZ212031A (en) 1988-08-30
NO162860B (no) 1989-11-20
FI851802L (fi) 1985-11-11

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