IL72664A - Controlled release pharmaceutical compositions comprising cross-linked,porous polymers - Google Patents

Controlled release pharmaceutical compositions comprising cross-linked,porous polymers

Info

Publication number
IL72664A
IL72664A IL72664A IL7266484A IL72664A IL 72664 A IL72664 A IL 72664A IL 72664 A IL72664 A IL 72664A IL 7266484 A IL7266484 A IL 7266484A IL 72664 A IL72664 A IL 72664A
Authority
IL
Israel
Prior art keywords
weight
water
ethanol
linked
cross
Prior art date
Application number
IL72664A
Other languages
English (en)
Other versions
IL72664A0 (en
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL72664A0 publication Critical patent/IL72664A0/xx
Publication of IL72664A publication Critical patent/IL72664A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
  • Organic Insulating Materials (AREA)
IL72664A 1983-08-15 1984-08-13 Controlled release pharmaceutical compositions comprising cross-linked,porous polymers IL72664A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/523,236 US4548990A (en) 1983-08-15 1983-08-15 Crosslinked, porous polymers for controlled drug delivery

Publications (2)

Publication Number Publication Date
IL72664A0 IL72664A0 (en) 1984-11-30
IL72664A true IL72664A (en) 1988-03-31

Family

ID=24084203

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72664A IL72664A (en) 1983-08-15 1984-08-13 Controlled release pharmaceutical compositions comprising cross-linked,porous polymers

Country Status (16)

Country Link
US (1) US4548990A (da)
EP (1) EP0140828B1 (da)
JP (1) JPS6067435A (da)
AT (1) ATE60997T1 (da)
AU (1) AU570712B2 (da)
CA (1) CA1225030A (da)
DE (1) DE3484165D1 (da)
DK (1) DK390584A (da)
ES (1) ES8604020A1 (da)
FI (1) FI80283C (da)
GR (1) GR80109B (da)
IL (1) IL72664A (da)
NO (1) NO167360C (da)
NZ (1) NZ209213A (da)
PT (1) PT79054B (da)
ZA (1) ZA846301B (da)

Families Citing this family (129)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983392A (en) * 1983-11-14 1991-01-08 Bio-Mimetics, Inc. Bioadhesive compositions and methods of treatment therewith
US4795436A (en) * 1983-11-14 1989-01-03 Bio-Mimetics, Inc. Bioadhesive composition and method of treatment therewith
US4675414A (en) * 1985-03-08 1987-06-23 The United States Of America As Represented By The Secretary Of The Navy Maleimidomethyl-carbonate polyethers
ATE78404T1 (de) * 1985-05-02 1992-08-15 Ciba Geigy Ag Hydrogele mit erhoehter beladungskapazitaet bezueglich einer in einem organischen loesungsmittel loeslichen wirksubstanz, deren herstellung sowie deren verwendung.
WO1986007541A1 (fr) * 1985-06-19 1986-12-31 Yasushi Zyo Composition susceptible d'avoir une activite anti-thrombotique et appareil medical devant etre en contact avec le sang
US4713244A (en) * 1985-08-16 1987-12-15 Bausch & Lomb Incorporated Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1 -C4) polar solvent
CA1295941C (en) * 1985-08-16 1992-02-18 Rajan Bawa Sustained-release formulation comprising a hydrophobic polymer system
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
US4783335A (en) * 1985-11-18 1988-11-08 The Kendall Company Controlled topical application of bioactive reagent
US5955109A (en) * 1985-12-18 1999-09-21 Advanced Polymer Systems, Inc. Methods and compositions for topical delivery of retinoic acid
US5879716A (en) * 1985-12-18 1999-03-09 Advanced Polymer Systems, Inc. Methods and compositions for topical delivery of benzoyl peroxide
US5145675A (en) * 1986-03-31 1992-09-08 Advanced Polymer Systems, Inc. Two step method for preparation of controlled release formulations
US4873086A (en) * 1986-03-03 1989-10-10 Ciba-Geigy Corporation Hydrogels with increased organic solvent soluble active agent loading capacity, their preparation and the use thereof
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
IL86211A (en) * 1987-05-04 1992-03-29 Ciba Geigy Ag Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
US4894239A (en) * 1987-06-02 1990-01-16 Takeda Chemical Industries, Ltd. Sustained-release preparation and production thereof
US5147923A (en) * 1987-10-05 1992-09-15 Ciba-Geigy Corporation Thermotropic biphilic hydrogels and hydroplastics
US5104954A (en) * 1987-10-05 1992-04-14 Ciba-Geigy Corporation Thermostropic biphilic hydrogels and hydroplastics
US5057560A (en) * 1987-10-05 1991-10-15 Ciba-Geigy Corporation Thermotropic copolymer hydrogels from N,N-dimethylacrylamide and methoxy-ethyl (meth) acrylate
US4910015A (en) * 1987-10-19 1990-03-20 Massachusetts Institute Of Technology Surface-active polysiloxanes and drug releasing materials thereof
JPH01113322A (ja) * 1987-10-23 1989-05-02 Tomoaki Fukuda アクリル系エマルジョンおよびこれを用いたpH非依存性遅延放出型製剤
US4983668A (en) * 1987-11-25 1991-01-08 Aristech Chemical Corporation Polymer partculates for molding and the like
US5019377A (en) * 1987-12-11 1991-05-28 The Procter & Gamble Company Low glass transistion temperature adhesive copolymers for use in hair styling products
EP0347145A3 (en) * 1988-06-14 1990-10-24 University Of Utah Research Foundation Heterogeneous interpenetrating polymer networks for the controlled release of drugs
US5073381A (en) * 1988-08-15 1991-12-17 University Of Akron Amphiphilic networks
WO1990004610A1 (fr) * 1988-10-27 1990-05-03 Mitsui Toatsu Chemicals, Inc. Procede de production d'un polymere particulaire
ATE113841T1 (de) 1989-10-31 1994-11-15 Columbia Lab Inc Mittel zur feuchthaltung vaginalen gewebes.
JP2510052B2 (ja) * 1989-10-31 1996-06-26 コロンビア ラボラトリーズ インコーポレイテッド 組織与湿組成物及び方法
US6017521A (en) * 1989-10-31 2000-01-25 Columbia Laboratories, Inc. Use of polycarboxylic acid polymers to treat vaginal infections
US5120532A (en) * 1990-04-06 1992-06-09 The Procter & Gamble Company Hair styling shampoos
US5120531A (en) * 1990-04-06 1992-06-09 The Procter & Gamble Company Hair styling conditioners
US5104642A (en) * 1990-04-06 1992-04-14 The Procter & Gamble Company Hair styling compositions containing particular hair styling polymers and non-aqueous solvents
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5262450A (en) * 1990-12-28 1993-11-16 Isp Investments Inc. Abrasion and water-resistant radiation curable coatings
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
JPH0819391B2 (ja) * 1992-11-30 1996-02-28 日東電工株式会社 感圧接着剤とその接着シ―ト類
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
US5969068A (en) * 1995-06-19 1999-10-19 The Lubrizol Corporation Dispersant-viscosity improvers for lubricating oil compositions
US5821313A (en) * 1995-06-19 1998-10-13 The Lubrizol Corporation Dispersant-viscosity improvers for lubricating oil compositions
CA2260992C (en) 1996-08-20 2004-03-09 The Regents Of The University Of California Eye treatments using synthetic thyroid hormone compositions
CA2270975C (en) 1997-07-02 2003-04-01 Euro-Celtique, S.A. Stabilized sustained release tramadol formulations
US6124249A (en) 1998-12-22 2000-09-26 The Lubrizol Corporation Viscosity improvers for lubricating oil compositions
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
DE19843903A1 (de) * 1998-09-24 2000-03-30 Basf Ag Feste Dosierungsform mit copolymerem Bindemittel
ES2212633T3 (es) * 1998-09-30 2004-07-16 Basf Aktiengesellschaft Empleo de polimeros hidrosolubles o dispersables en agua, que contienen polieter como agente de recubrimiento, aglutinante y/o producto auxiliar formador de pelicula en formas de presentacion farmaceuticas.
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US6521431B1 (en) 1999-06-22 2003-02-18 Access Pharmaceuticals, Inc. Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
US6558607B1 (en) 1999-09-30 2003-05-06 University Of Massachusetts Crystallization of constrained polymers
KR20020059653A (ko) 1999-10-29 2002-07-13 그린 마틴, 브라이언 쥐 테슬리 서방성 하이드로코돈 제형
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
US7141607B1 (en) 2000-03-10 2006-11-28 Insite Vision Incorporated Methods and compositions for treating and inhibiting retinal neovascularization
ATE377048T1 (de) 2000-09-06 2007-11-15 Ap Pharma Inc Abbaubare polyacetal-polymere
EP1337244A4 (en) 2000-10-30 2006-01-11 Euro Celtique Sa HYDROCODON FORMULATIONS WITH CONTROLLED RELEASE
UA81224C2 (uk) * 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US6590059B2 (en) 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
DE10128531A1 (de) * 2001-06-13 2002-12-19 Basf Ag Verwendung von wasserlöslichen oder wasserdispergierbaren Polyetherblöcke enthaltenden Pfropfpolymerisaten als Beschichtungsmittel, Matrixbildner und/oder Verpackungsmaterial für Agrochemikalien
US6921390B2 (en) 2001-07-23 2005-07-26 Boston Scientific Scimed, Inc. Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface
US6524606B1 (en) 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
FR2833961B1 (fr) * 2001-12-20 2004-04-02 Virsol Procede de preparation de films a base de poly(oxyde d'ethylene) reticule
GB0205868D0 (en) * 2002-03-13 2002-04-24 Univ Nottingham Polymer composite with internally distributed deposition matter
CA2532414C (en) 2003-07-12 2017-03-14 Accelr8 Technology Corporation Sensitive and rapid biodetection
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
PT2348023E (pt) * 2005-12-13 2015-09-15 Incyte Corp Pirrolo[2,3-b] pirimidinas e pirrolo[2,3-b]piridinas substituídas com heteroarilo como inibidores de janus quinase
US20080069871A1 (en) * 2006-07-21 2008-03-20 Vaughn Jason M Hydrophobic abuse deterrent delivery system
ES2714092T3 (es) 2007-06-13 2019-05-27 Incyte Holdings Corp Uso de sales del inhibidor de quinasas Janus (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-ciclopentilpropanonitrilo
US20090005362A1 (en) * 2007-06-26 2009-01-01 Vo Toan P Compositions Comprising Antihistamines or Mast Cell Stabilizers, and Methods of Making and Using Same
US7795231B2 (en) 2007-10-04 2010-09-14 Insite Vision Incorporated Concentrated aqueous azalide formulations
SI2288610T1 (sl) 2008-03-11 2016-11-30 Incyte Holdings Corporation Derivati azetidina in ciklobutana kot inhibitorji jak
GB0812742D0 (en) * 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
CL2009001884A1 (es) * 2008-10-02 2010-05-14 Incyte Holdings Corp Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
US8778999B2 (en) 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
US8501800B2 (en) * 2009-03-05 2013-08-06 Insite Vision Incorporated Controlled-release ophthalmic vehicles
US20170128481A9 (en) 2009-03-06 2017-05-11 Insite Vision Corporation Ocular treatment with reduced intraocular pressure
US10201548B2 (en) 2009-03-06 2019-02-12 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US10980818B2 (en) 2009-03-06 2021-04-20 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
EP2408828A4 (en) * 2009-03-19 2013-10-09 Agency Science Tech & Res FORMATION OF COPOLYMER FROM BICONTINUOUS MICROEMULSION THAT CONTAINS MONOMERS OF DIFFERENT HYDROPHILY
SG176130A1 (en) 2009-05-22 2011-12-29 Incyte Corp N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS
ME03556B (me) * 2009-05-22 2020-07-20 Incyte Holdings Corp 3-[4-(7h-pirolo[2,3-d]pirimidin-4-il)-1 h-pirazol-1-il]oktan- ili нертan - niтril kао јак inhibiтori
US8563760B2 (en) * 2009-08-31 2013-10-22 Mayo Foundation For Medical Education And Research Process for the synthesis of long-chain fatty acids
AR078012A1 (es) 2009-09-01 2011-10-05 Incyte Corp Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus
TWI694826B (zh) 2010-03-10 2020-06-01 美商英塞特公司 作為jak1抑制劑之哌啶-4-基三亞甲亞胺衍生物
MY178634A (en) 2010-05-21 2020-10-19 Incyte Corp Topical formulation for a jak inhibitor
CA2818545C (en) 2010-11-19 2019-04-16 Incyte Corporation Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
EP2640723A1 (en) 2010-11-19 2013-09-25 Incyte Corporation Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
ES2551922T3 (es) 2011-03-07 2015-11-24 Accelerate Diagnostics, Inc. Sistemas rápidos de purificación celular
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
KR20140040819A (ko) 2011-06-20 2014-04-03 인사이트 코포레이션 Jak 저해제로서의 아제티디닐 페닐, 피리딜 또는 피라지닐 카르복스아미드 유도체
TW201313721A (zh) 2011-08-18 2013-04-01 Incyte Corp 作為jak抑制劑之環己基氮雜環丁烷衍生物
UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
FR2987561B1 (fr) * 2012-03-02 2014-04-11 Pf Medicament Dispositif transdermique comprenant des micro-particules poreuses
US9193733B2 (en) 2012-05-18 2015-11-24 Incyte Holdings Corporation Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors
RU2670943C9 (ru) 2012-11-08 2018-11-26 Илэвэн Байотерапьютикс, Инк. Антагонисты ил-6 и их применение
KR20210037012A (ko) 2012-11-15 2021-04-05 인사이트 홀딩스 코포레이션 룩솔리티니브의 서방성 제형
WO2014107737A2 (en) 2013-01-07 2014-07-10 Eleven Biotherapeutics, Inc. Local delivery of il-17 inhibitors for treating ocular disease
SI2964650T1 (sl) 2013-03-06 2019-05-31 Incyte Holdings Corporation Postopki in vmesne spojine za izdelavo inhibitorja JAK
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
US9044508B2 (en) 2013-03-15 2015-06-02 Insite Vision Corporation Concentrated aqueous azalide formulations
EA201690357A1 (ru) 2013-08-07 2016-07-29 Инсайт Корпорейшн Лекарственные формы с замедленным высвобождением для ингибитора jak1
EP3119392A4 (en) 2014-03-17 2017-10-11 Encompass Development Inc. Ocular formulations
US9498467B2 (en) 2014-05-30 2016-11-22 Incyte Corporation Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
CA2936746C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
ES3051832T3 (en) 2014-11-07 2025-12-30 F Hoffmann La Roche Ltd Improved il-6 antibodies
WO2016073894A1 (en) 2014-11-07 2016-05-12 Eleven Biotherapeutics, Inc. Therapeutic agents with increased ocular retention
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
KR20170132856A (ko) 2015-03-30 2017-12-04 액셀러레이트 다이어그노스틱스, 아이엔씨. 신속한 미생물 동정 및 항균제 감수성 시험을 위한 기기 및 시스템
WO2017019808A1 (en) 2015-07-27 2017-02-02 Catacore, Inc Compositions for the treatment of cataracts
KR20180116359A (ko) 2016-02-23 2018-10-24 세센 바이오, 아이엔씨. 인터루킨-6의 길항제 제제 및 이의 용도
AR113922A1 (es) 2017-12-08 2020-07-01 Incyte Corp Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
UA127488C2 (uk) 2018-01-30 2023-09-06 Інсайт Корпорейшн Способи одержання (1-(3-фтор-2-(трифторметил)ізонікотиноїл)піперидин-4-ону)
US11304949B2 (en) 2018-03-30 2022-04-19 Incyte Corporation Treatment of hidradenitis suppurativa using JAK inhibitors
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
KR102151051B1 (ko) 2019-01-10 2020-09-02 고려대학교 산학협력단 당뇨병성 백내장 치료 또는 예방용 조성물
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE636865A (da) * 1962-08-31
CH468192A (de) * 1964-06-19 1969-02-15 Ciba Geigy Verfahren zur Herstellung von Arzneimitteln in Perlenform
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
US4184020A (en) * 1970-11-24 1980-01-15 Ceskoslovenska Akademie Ved Preparation of hydrophilic material for gel chromatography
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
GB1456365A (en) * 1972-10-06 1976-11-24 Gist Brocades Nv Controlled release composition
US4192827A (en) * 1974-06-27 1980-03-11 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers
US4177056A (en) * 1974-06-27 1979-12-04 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides
HU174057B (hu) * 1976-09-17 1979-10-28 Richter Gedeon Vegyeszet Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva
US4136250A (en) * 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4224427A (en) * 1978-06-01 1980-09-23 Ciba-Geigy Corporation Process for preparing hydrogels as spherical beads of large size
US4379864A (en) * 1979-02-09 1983-04-12 Syntex (U.S.A.) Inc. Polymeric compositions and hydrogels formed therefrom
JPS55149212A (en) * 1979-05-11 1980-11-20 Toray Ind Inc Gradually releasing preparation of methotrexate

Also Published As

Publication number Publication date
NZ209213A (en) 1986-12-05
ES535129A0 (es) 1986-01-16
DK390584D0 (da) 1984-08-14
JPS6067435A (ja) 1985-04-17
CA1225030A (en) 1987-08-04
EP0140828A2 (de) 1985-05-08
PT79054A (en) 1984-09-01
FI843190A7 (fi) 1985-02-16
ES8604020A1 (es) 1986-01-16
EP0140828B1 (de) 1991-02-27
FI80283B (fi) 1990-01-31
FI843190A0 (fi) 1984-08-13
NO843237L (no) 1985-02-18
NO167360C (no) 1991-10-30
DK390584A (da) 1985-02-16
AU3189684A (en) 1985-02-21
FI80283C (fi) 1990-05-10
GR80109B (en) 1984-12-14
NO167360B (no) 1991-07-22
PT79054B (en) 1987-06-03
EP0140828A3 (en) 1987-02-04
DE3484165D1 (de) 1991-04-04
US4548990A (en) 1985-10-22
ZA846301B (en) 1985-05-29
ATE60997T1 (de) 1991-03-15
AU570712B2 (en) 1988-03-24
IL72664A0 (en) 1984-11-30

Similar Documents

Publication Publication Date Title
IL72664A (en) Controlled release pharmaceutical compositions comprising cross-linked,porous polymers
CA2037410A1 (en) Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films, and their preparation process
KR950005301A (ko) 방출 개시 제어 및 방출 속도 제어형 제제
GB1135966A (en) Improvements in or relating to sustained-release medicaments
WO1995020610A3 (en) Two-phase acidic aqueous compositions for diffusion transfer products
CA2290624A1 (en) Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
IE870064L (en) Sustained release capsule
DE3373417D1 (en) Use of a sulfonated homo- or copolymer of styrene for the manufacture of a contraceptive composition
Bae et al. Heterogeneous interpenetrating polymer networks for drug delivery
JPS55165906A (en) Preparation of acrylamide polymer
EP0190996A3 (en) Crosslinked, porous polymers for controlled delivery of agricultural ingredients
JPS5483989A (en) Preparation of hydrophilic polymer
JPS51131559A (en) Aqueous composition of vinyl copolymer with good stability and process for preparing it
JPS51144481A (en) Preparing low molecular weight copolymers
JPS5765328A (en) Water absorbing composition having shape imparting property
JPS55149212A (en) Gradually releasing preparation of methotrexate
JPS57130907A (en) Amlgam coating agent
JPS52105992A (en) Preparation of hydrophilic high polymers
JPS51144482A (en) Preparing low molecular weight copolymers
JPS577415A (en) Fomentation
JPS53147791A (en) Preparation of vinyl chloride polymer having low polymerization degree
JPS5337790A (en) Preparation of block copolymer