IL72642A - Circular dna plasmid for use as transformation vector - Google Patents

Circular dna plasmid for use as transformation vector

Info

Publication number
IL72642A
IL72642A IL72642A IL7264284A IL72642A IL 72642 A IL72642 A IL 72642A IL 72642 A IL72642 A IL 72642A IL 7264284 A IL7264284 A IL 7264284A IL 72642 A IL72642 A IL 72642A
Authority
IL
Israel
Prior art keywords
circular dna
transformation vector
dna plasmid
plasmid
transformation
Prior art date
Application number
IL72642A
Other languages
English (en)
Other versions
IL72642A0 (en
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL72642A0 publication Critical patent/IL72642A0/xx
Priority to IL99611A priority Critical patent/IL99611A0/xx
Publication of IL72642A publication Critical patent/IL72642A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL72642A 1983-08-10 1984-08-10 Circular dna plasmid for use as transformation vector IL72642A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL99611A IL99611A0 (en) 1983-08-10 1991-09-29 Dna plasmids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52196483A 1983-08-10 1983-08-10
US06/636,727 US4710473A (en) 1983-08-10 1984-08-06 DNA plasmids

Publications (2)

Publication Number Publication Date
IL72642A0 IL72642A0 (en) 1984-11-30
IL72642A true IL72642A (en) 1993-04-04

Family

ID=27060650

Family Applications (2)

Application Number Title Priority Date Filing Date
IL72642A IL72642A (en) 1983-08-10 1984-08-10 Circular dna plasmid for use as transformation vector
IL9961184A IL99611A (en) 1983-08-10 1984-08-10 Small stabilized ILOC .E plasmids

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL9961184A IL99611A (en) 1983-08-10 1984-08-10 Small stabilized ILOC .E plasmids

Country Status (7)

Country Link
US (2) US4710473A (ja)
EP (1) EP0136490B1 (ja)
JP (1) JPH0797991B2 (ja)
CA (1) CA1312026C (ja)
DE (1) DE3481716D1 (ja)
IL (2) IL72642A (ja)
WO (1) WO1985000829A1 (ja)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000831A1 (en) * 1983-08-10 1985-02-28 Amgen Microbial expression of insulin-like growth factor
US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
KR850004274A (ko) * 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
US5126252A (en) * 1984-08-27 1992-06-30 Bio-Technology General Corp. Expressions vectors containing Lambda PL promoter and T1 T2 RNA termination sequence, plasmids containing the vectors, hosts containing the plasmids and relatedmethods
US5081020A (en) * 1984-08-27 1992-01-14 Bio-Technology General Corp. Expression vectors containing λPL promoter, T1 T2 rRNA termination sequence and origin of replication derived from a constitutive high copy number plasmid hosts and related methods
US5759816A (en) * 1984-08-27 1998-06-02 Bio-Technology General Corp. Expression vectors containing λPL promoter and T1 T2 rRNA termination sequence plasmids containing the vectors hosts containing the plasmids and related methods
JP2594535B2 (ja) * 1984-11-30 1997-03-26 サントリー株式会社 高発現ベクターおよびその利用
US4810643A (en) * 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
JPS63500636A (ja) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 多分化能性顆粒球コロニー刺激因子をコードするｄｎａ
US6004548A (en) 1985-08-23 1999-12-21 Amgen, Inc. Analogs of pluripotent granulocyte colony-stimulating factor
US5110731A (en) * 1985-08-26 1992-05-05 Amgen, Inc. System for biotin synthesis
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
WO1988006186A2 (en) * 1987-02-19 1988-08-25 The Upjohn Company cDNAs ENCODING SOMATOTROPIN, EXPRESSION VECTORS AND HOSTS
US5240837A (en) * 1987-02-19 1993-08-31 The Upjohn Company CDNAS encoding somatotropin, expression vectors and hosts
US5472702A (en) * 1987-08-26 1995-12-05 United States Surgical Corporation Sterilization of growth factors
US5222978A (en) 1987-08-26 1993-06-29 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5366081A (en) 1987-08-26 1994-11-22 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US4885252A (en) * 1987-09-08 1989-12-05 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans
US5599690A (en) * 1988-02-01 1997-02-04 Amgen Inc. Control of norleucine incorporation into recombinant proteins
US5714465A (en) * 1989-05-19 1998-02-03 Amgen Inc. Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor
WO1990014363A1 (en) 1989-05-19 1990-11-29 Amgen Inc. Metalloproteinase inhibitor
US5359831A (en) 1989-08-01 1994-11-01 United States Surgical Corporation Molded suture retainer
US5434135A (en) * 1990-08-02 1995-07-18 Indu Parikh Growth factor compositions, preparation and use
IL99100A0 (en) * 1990-08-13 1992-07-15 Lilly Co Eli Improved bacteriophage lambda pl promoters
CA2069741C (en) * 1990-09-28 1996-06-18 Kwang-Mu Yen Cloning cartridges and expression vectors in gram-negative bacteria
CA2057715A1 (en) * 1990-12-19 1992-06-20 Charles L. Hershberger Method for enhancing the structural stability of recombinant dna expression vectors
CA2059245C (en) * 1991-02-08 2004-07-06 Michael P. Chesterfield Method and apparatus for calendering and coating/filling sutures
US5395761A (en) * 1991-11-27 1995-03-07 Eli Lilly And Company Plasmid pHKY334, an expression vector for EK-BGH and host cells transformed therewith
IL107642A0 (en) * 1992-11-20 1994-02-27 Amgen Inc Progenitor b cell stimulating factor
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US6562596B1 (en) 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US5446024A (en) * 1993-12-17 1995-08-29 Genentech, Inc. Purification of insulin-like growth factor
US5574008A (en) 1994-08-30 1996-11-12 Eli Lilly And Company Biologically active fragments of glucagon-like insulinotropic peptide
IL117175A (en) * 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US5904716A (en) * 1995-04-26 1999-05-18 Gendler; El Method for reconstituting cartilage tissue using demineralized bone and product thereof
US20030207827A1 (en) * 1995-12-22 2003-11-06 William J. Boyle Osteoprotegerin
US20050147611A1 (en) * 1995-12-22 2005-07-07 Amgen Inc. Combination therapy for conditions leading to bone loss
US6369027B1 (en) 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin
US7632922B1 (en) * 1995-12-22 2009-12-15 Amgen, Inc. Osteoprotegerin
AU718382B2 (en) * 1996-11-08 2000-04-13 Neose Technologies, Inc. Improved expression vectors
TR199901734T2 (xx) * 1996-11-15 2000-01-21 Genentech, Inc. N�rotrofinlerin ar�t�lmas�.
EP2371962A3 (en) 1996-12-23 2011-12-21 Immunex Corporation Receptor activator of NF-KAPPA B, receptor is member of TNF receptor superfamily
EP0911342B2 (en) * 1997-04-15 2013-05-22 Daiichi Sankyo Company, Limited Novel protein and process for producing the same
US6316408B1 (en) * 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
JP2001526532A (ja) 1997-04-16 2001-12-18 アムジエン・インコーポレーテツド オステオプロテゲリン結合性蛋白および受容体
US6265542B1 (en) 1997-10-24 2001-07-24 Genentech, Inc. Purification of molecules
AU6788900A (en) * 1999-09-03 2001-04-10 Amgen, Inc. Compositions and methods for the prevention or treatment of cancer and bone loss associated with cancer
KR100814313B1 (ko) * 2000-04-06 2008-03-18 교와 핫꼬 고교 가부시끼가이샤 대장균의 염색체 재조합에 사용되는 플라스미드
US6780405B1 (en) * 2000-04-28 2004-08-24 Avant Immunotherapeutics, Inc. Regulated antigen delivery system (RADS)
CA2412277A1 (en) * 2000-09-08 2002-03-14 Gryphon Therapeutics, Inc. Synthetic erythropoiesis stimulating proteins
ES2324645T3 (es) 2000-11-03 2009-08-12 Genentech, Inc. Cambios de tasa metabolica en fermentaciones que expresen proteinas recombinantes.
IL158719A0 (en) 2001-05-11 2004-05-12 Amgen Inc Peptides and related molecules that bind to tall-1
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
AU2003243139B2 (en) 2002-04-05 2007-06-21 Amgen Inc. Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
US6919426B2 (en) 2002-09-19 2005-07-19 Amgen Inc. Peptides and related molecules that modulate nerve growth factor activity
EP1684791A4 (en) 2003-10-27 2009-07-01 Amgen Inc COMPOSITIONS AND METHODS FOR MODULATION OF IMMUNE REACTION TO AN IMMUNOGENIC THERAPEUTIC AGENT
ME00226B (me) 2004-07-15 2011-02-10 Medarex Llc Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
ES2446416T3 (es) 2005-12-09 2014-03-07 Amgen, Inc. Compuestos basados en quinolona que presentan actividad inhibidora de prolil hidroxilasa, composiciones y usos de los mismos
MY143274A (en) 2005-12-22 2011-04-15 Genentech Inc Recombinant production of heparin binding proteins
SG162834A1 (en) 2006-07-14 2010-07-29 Genentech Inc Refolding of recombinant proteins
ES2393326T3 (es) * 2006-12-18 2012-12-20 Amgen, Inc Compuestos basados en azaquinolona que presentan actividad inhibidora de prolil hidroxilasas, composiciones y usos de los mismos
EP2111399A2 (en) * 2006-12-18 2009-10-28 Amgen Inc. Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
CA2683738C (en) * 2007-04-18 2012-03-20 Amgen Inc. Indanone derivatives that inhibit prolyl hydroxylase
US8048894B2 (en) * 2007-04-18 2011-11-01 Amgen Inc. Quinolones and azaquinolones that inhibit prolyl hydroxylase
US8097620B2 (en) * 2007-05-04 2012-01-17 Amgen Inc. Diazaquinolones that inhibit prolyl hydroxylase activity
CA2685216C (en) * 2007-05-04 2014-07-08 Amgen Inc. Thienopyridine and thiazolopyridine derivatives that inhibit prolyl hydroxylase activity
US20090192554A1 (en) 2008-01-29 2009-07-30 Confluent Surgical, Inc. Bioabsorbable block copolymer
US8748097B1 (en) 2011-12-02 2014-06-10 President And Fellows Of Harvard College Identification of agents for treating calcium disorders and uses thereof
EP4168557A1 (en) * 2020-06-17 2023-04-26 Basf Se Plasmid copy number regulation and integration

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2759053A1 (de) * 1977-12-30 1979-07-12 Uhlin Verfahren zum herstellen von genprodukten von plasmid-dns
FI793884A (fi) * 1978-12-26 1980-06-27 Cetus Corp Stabila plasmider med stort kopieantal
US4374927A (en) * 1981-02-24 1983-02-22 The Board Of Trustees Of The Leland Stanford Jr. University Extrachromosomal regulation of expression
CA1198067A (en) * 1981-02-27 1985-12-17 David H. Gelfand Stable high copy number plasmids
WO1983004030A1 (en) * 1982-05-06 1983-11-24 Applied Molecular Genetics, Inc. The manufacture and expression of genes for urogastrone and polypeptide analogs thereof
JPH0753111B2 (ja) * 1982-09-16 1995-06-07 ベンツォン ファーマ エイ／エス 条件非制御の複製挙動を持つプラスミド
CA1209501A (en) * 1982-09-16 1986-08-12 Nikos Panayotatos Expression vector
DK410783D0 (da) * 1982-09-16 1983-09-09 Benzon A Salfred Fremgangsmade til stabilisering af plasmider
WO1984001150A1 (en) * 1982-09-16 1984-03-29 Amgen Avian growth hormones
NL8203716A (nl) * 1982-09-24 1984-04-16 Tno Dna en plasmiden.
GB8308236D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Dna vectors

Also Published As

Publication number Publication date
IL99611A (en) 1994-01-25
IL72642A0 (en) 1984-11-30
WO1985000829A1 (en) 1985-02-28
EP0136490A3 (en) 1985-10-09
JPS60501988A (ja) 1985-11-21
US5674746A (en) 1997-10-07
US4710473A (en) 1987-12-01
JPH0797991B2 (ja) 1995-10-25
EP0136490B1 (en) 1990-03-21
EP0136490A2 (en) 1985-04-10
DE3481716D1 (de) 1990-04-26
CA1312026C (en) 1992-12-29

Similar Documents

Publication Publication Date Title
IL72642A (en) Circular dna plasmid for use as transformation vector
DE3275837D1 (en) Plasmid, process for its preparation and its use as vector
GB2197653B (en) Chimeric genes
GB8305358D0 (en) Spatial transformation system
DE3368369D1 (en) Implement guidance system
JPS5636499A (en) Dna introduced vector
GB8305786D0 (en) Human antithrombim iii dna sequences
GB2091269B (en) Plasmid cloning vehicles
GB8411001D0 (en) Bi-polar adaptor
DE3479322D1 (en) Dna sequence
GB8626914D0 (en) Dna clone
DE3379784D1 (en) Hand trolley
IL72666A0 (en) Plasmid vector
DE3380210D1 (en) Articulated vessel
EP0091723A3 (en) Transposable cloning vector
GB8310905D0 (en) Heating for horticulture
EP0112976A3 (en) Novel dna and r combinant plasmid containing the same
EP0093834A3 (en) Sequence controller
GB8400828D0 (en) Dna expression vectors
GB8310742D0 (en) Plasmid cloning vector
JPS55132352A (en) Skid controller
JPS5598083A (en) Positional controller
IL69926A0 (en) Plasmid expression vector and processes for the production thereof
GB2066459B (en) Light-activated control system
JPS55140636A (en) Skid controller

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
EXP Patent expired