IL71969A - 3-substituted aminomethyl cephalosporin derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

3-substituted aminomethyl cephalosporin derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL71969A
IL71969A IL71969A IL7196984A IL71969A IL 71969 A IL71969 A IL 71969A IL 71969 A IL71969 A IL 71969A IL 7196984 A IL7196984 A IL 7196984A IL 71969 A IL71969 A IL 71969A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
cephalosporin derivatives
substituted aminomethyl
aminomethyl cephalosporin
Prior art date
Application number
IL71969A
Other languages
English (en)
Other versions
IL71969A0 (en
Original Assignee
Ici Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Pharma filed Critical Ici Pharma
Publication of IL71969A0 publication Critical patent/IL71969A0/xx
Publication of IL71969A publication Critical patent/IL71969A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL71969A 1983-06-03 1984-05-30 3-substituted aminomethyl cephalosporin derivatives,their preparation and pharmaceutical compositions comprising them IL71969A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP83401135 1983-06-03

Publications (2)

Publication Number Publication Date
IL71969A0 IL71969A0 (en) 1984-09-30
IL71969A true IL71969A (en) 1988-03-31

Family

ID=8191406

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71969A IL71969A (en) 1983-06-03 1984-05-30 3-substituted aminomethyl cephalosporin derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (19)

Country Link
US (1) US4678781A (de)
EP (1) EP0127992B1 (de)
JP (1) JPH0633283B2 (de)
KR (1) KR910008352B1 (de)
AU (1) AU585831B2 (de)
CA (1) CA1272188A (de)
DE (1) DE3486033T2 (de)
DK (1) DK271584A (de)
ES (1) ES533084A0 (de)
FI (1) FI80043C (de)
GB (1) GB8413152D0 (de)
GR (1) GR81617B (de)
HU (1) HU196811B (de)
IL (1) IL71969A (de)
NO (1) NO164301C (de)
NZ (1) NZ208360A (de)
PH (1) PH22334A (de)
PT (1) PT78685B (de)
ZA (1) ZA844052B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855420A (en) * 1983-06-03 1989-08-08 Ici Pharma Cephalosporin derivatives
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
EP0187456A1 (de) * 1984-11-29 1986-07-16 Ici Pharma Cephalosporinverbindungen
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
GB8626245D0 (en) * 1985-11-27 1986-12-03 Ici Pharma Cephalosporin compounds
US4684722A (en) * 1986-01-06 1987-08-04 E. R. Squibb & Sons, Inc. Monosulfactams
GB8611823D0 (en) * 1986-05-15 1986-06-25 Ici Plc Process
ZA877987B (en) * 1986-11-12 1988-08-31 Ici Pharma Antibiotic compounds
DE3750673T2 (de) * 1986-11-21 1995-03-16 Ici Pharma Cephalosporine, Verfahren zu ihrer Herstellung und pharmazeutische Präparate.
US5262410A (en) * 1986-12-23 1993-11-16 Ici Pharma 3-heterocyclic thiomethyl cephalosporins
EP0272827A3 (de) * 1986-12-23 1990-02-07 ZENECA Pharma S.A. 3-Heterocyclethiomethyl-cephalosporine
GB8816519D0 (en) * 1987-07-23 1988-08-17 Ici Plc Antibiotic compounds
DE3854804T2 (de) * 1987-07-23 1996-06-13 Zeneca Pharma Sa Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
US5232918A (en) * 1987-07-23 1993-08-03 Imperial Chemical Industries Plc Cephalosporin derivatives
ATE130299T1 (de) * 1987-07-23 1995-12-15 Zeneca Pharma Sa Cephalosporinverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische präparate.
AT395854B (de) * 1991-05-24 1993-03-25 Biochemie Gmbh Neues verfahren zur herstellung von 7-amino-3azidomethyl-3-cephem-4-carbonsaeure und deren derivate
US5817520A (en) * 1991-12-20 1998-10-06 Oxis International S.A. Spectrophotometric methods for assaying total mercaptans, reduced glutathione (GSH) and mercaptans other than GSH in an aqueous medium reagents and kits for implementing same
DE19647413A1 (de) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE10225537A1 (de) * 2002-06-10 2003-12-18 Bayer Ag N-alkylierte Thiazoliumsalze und Verfahren zu deren Herstellung
CN103502218B (zh) 2011-03-04 2016-08-17 生命科技公司 用于缀合生物分子的化合物和方法
JP7158717B2 (ja) * 2017-11-22 2022-10-24 国立大学法人九州工業大学 求電子的アジド化剤又はジアゾ化剤

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584713A (de) * 1967-01-18 1970-01-02
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
FR2432521A1 (fr) 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2818263A1 (de) * 1978-04-26 1979-11-08 Bayer Ag Beta-lactamantibiotika
GB1604724A (en) * 1978-05-26 1981-12-16 Glaxo Operations Ltd 7-(2-aminothiazol-4-yl)-2-oxymino-acedamido)-cephem derivatives
JPS54154786A (en) * 1978-05-26 1979-12-06 Glaxo Group Ltd Cephalosporin compound
GB2036738B (en) * 1978-11-17 1983-01-19 Glaxo Group Ltd Cephalosporin antibiotics
GB2046261B (en) * 1979-03-22 1983-07-20 Glaxo Group Ltd Cephalosporin antibiotics
EP0018595B1 (de) * 1979-04-27 1986-08-20 Merck & Co. Inc. 7-N-Heterocyclyl-Cephalosporinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzung
JPS57167993A (en) * 1981-04-09 1982-10-16 Yamanouchi Pharmaceut Co Ltd Novel 3-((4-carboxy-3-hydroxyisothiazole-5-yl) thiomethyl)-delta3-cephem derivative
GB2103205A (en) * 1981-06-15 1983-02-16 Fujisawa Pharmaceutical Co New cephem compounds
AU8474382A (en) * 1981-06-19 1982-12-23 Imperial Chemical Industries Plc Process of preparing cephalosporin antibiotics
JPS5876088A (ja) * 1981-10-27 1983-05-09 Nippon Paint Co Ltd 固定化植物組織
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins
FR2516515A1 (fr) * 1981-11-16 1983-05-20 Sanofi Sa Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2530248A1 (fr) * 1982-07-13 1984-01-20 Sanofi Sa Nouveaux derives des cephalosporines, leur procede de preparation et medicaments antibiotiques contenant lesdits derives
HU188874B (en) * 1983-04-19 1986-05-28 Biogal Gyogyszergyar,Hu Process for producing new 7-acylamido-3-acylaminomethyl-ceph-3-eme-4-carboxylic acid derivatives and pharmaceutically acceptable salts thereof
US4560749A (en) * 1983-11-18 1985-12-24 Eli Lilly And Company Cephem-3-imidates and 3-amidines
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.

Also Published As

Publication number Publication date
FI842211A (fi) 1984-12-04
AU2894384A (en) 1984-12-06
JPS6045584A (ja) 1985-03-12
FI80043B (fi) 1989-12-29
NO164301C (no) 1990-09-19
EP0127992B1 (de) 1993-01-13
NZ208360A (en) 1988-01-08
FI80043C (fi) 1990-04-10
HU196811B (en) 1989-01-30
ZA844052B (en) 1985-01-30
PT78685A (de) 1984-06-01
AU585831B2 (en) 1989-06-29
DE3486033T2 (de) 1993-05-06
KR850000458A (ko) 1985-02-27
HUT34499A (en) 1985-03-28
NO842214L (no) 1984-12-04
ES8601213A1 (es) 1985-10-16
DE3486033D1 (de) 1993-02-25
GB8413152D0 (en) 1984-06-27
CA1272188A (en) 1990-07-31
GR81617B (de) 1984-12-11
DK271584D0 (da) 1984-06-01
ES533084A0 (es) 1985-10-16
DK271584A (da) 1984-12-04
EP0127992A2 (de) 1984-12-12
NO164301B (no) 1990-06-11
US4678781A (en) 1987-07-07
PT78685B (en) 1986-10-21
JPH0633283B2 (ja) 1994-05-02
PH22334A (en) 1988-08-12
EP0127992A3 (en) 1985-11-21
FI842211A0 (fi) 1984-06-01
KR910008352B1 (ko) 1991-10-12
IL71969A0 (en) 1984-09-30

Similar Documents

Publication Publication Date Title
IL73756A (en) 5-sulfamoylalkyl-3-aminoalkyl indole derivatives,their preparation and pharmaceutical compositions containing them
IL71969A (en) 3-substituted aminomethyl cephalosporin derivatives,their preparation and pharmaceutical compositions comprising them
EP0120669A3 (en) Hydroxypyridones, and their pharmaceutical compositions
IL70756A0 (en) 3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL71249A0 (en) Thiazolidine derivatives,their preparation and pharmaceutical compositions containing them
IL73008A0 (en) Azole derivatives,their preparation and pharmaceutical compositions containing them
IL72151A (en) Tetrahydropyridazinone derivatives,their preparation and pharmaceutical compositions containing them
IL71633A0 (en) Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL71481A0 (en) Substituted indeno-pyridazinones,their preparation and pharmaceutical compositions containing them
IL70755A (en) 3-amino-4-cyano-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL68011A0 (en) Cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
IL72054A0 (en) Beta-lactam derivative,its preparation and pharmaceutical compositions containing it
IL73222A0 (en) Benzenesulfonyl-lactam derivatives,their preparation and pharmaceutical compositions containing them
IL73897A0 (en) Benzimidazole derivatives,their preparation and pharmaceutical compositions containing them
IL72123A0 (en) Substituted phenylalkyl-piperazinyl-and homopiperazinyl-propyl-ureas and-thioureas,their preparation and pharmaceutical compositions containing them
IL85970A0 (en) Cephalosporin derivatives,their manufacture and pharmaceutical compositions containing them
IL70611A (en) Tetrahydrocarbazole derivatives,their preparation and pharmaceutical compositions comprising them
IL72173A0 (en) Guanine derivatives,their preparation and pharmaceutical compositions containing them
IL69324A0 (en) Fluoralkylated carbapenem derivatives,their preparation and pharmaceutical compositions containing them
IL73776A (en) N-phenyl-1h-tetrazole-5-carboxamide derivatives,their preparation and pharmaceutical compositions containing them
IL72757A0 (en) Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL73231A (en) 1-acetylaminophenyl-2-amino-propanone derivatives,their preparation and pharmaceutical compositions containing them
IL72480A0 (en) Benzamidine derivatives,their preparation and pharmaceutical compositions containing them
IL71078A (en) Pharmaceutical compositions comprising n-aminoethyl-benzamide derivatives,certain such novel compounds and their preparation
DE3469176D1 (en) 2,6-dioxopiperidine derivatives, their preparation and pharmaceutical compositions containing them