IL67929A - 1-methyl-5-p-toluoylpyrrole-2-acetic acid amides,their preparation and pharmaceutical compositions comprising them - Google Patents
1-methyl-5-p-toluoylpyrrole-2-acetic acid amides,their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- IL67929A IL67929A IL8367929A IL6792983A IL67929A IL 67929 A IL67929 A IL 67929A IL 8367929 A IL8367929 A IL 8367929A IL 6792983 A IL6792983 A IL 6792983A IL 67929 A IL67929 A IL 67929A
- Authority
- IL
- Israel
- Prior art keywords
- toluoylpyrrole
- methyl
- preparation
- acetic acid
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8247881A IT1210673B (it) | 1982-02-26 | 1982-02-26 | Antinfiammatoria amidi pirrolacetiche ad attivita' |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL67929A0 IL67929A0 (en) | 1983-06-15 |
| IL67929A true IL67929A (en) | 1986-10-31 |
Family
ID=11263094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL8367929A IL67929A (en) | 1982-02-26 | 1983-02-16 | 1-methyl-5-p-toluoylpyrrole-2-acetic acid amides,their preparation and pharmaceutical compositions comprising them |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US4882349A (fi) |
| JP (2) | JPS58159458A (fi) |
| KR (1) | KR890004127B1 (fi) |
| AT (1) | AT376204B (fi) |
| BE (1) | BE896018A (fi) |
| CA (1) | CA1207769A (fi) |
| CH (1) | CH658650A5 (fi) |
| DE (1) | DE3306006A1 (fi) |
| DK (1) | DK155792C (fi) |
| ES (1) | ES8403453A1 (fi) |
| FI (1) | FI77227C (fi) |
| FR (1) | FR2522324B1 (fi) |
| GB (1) | GB2115417B (fi) |
| GR (1) | GR77920B (fi) |
| IE (1) | IE54896B1 (fi) |
| IL (1) | IL67929A (fi) |
| IT (1) | IT1210673B (fi) |
| LU (1) | LU84660A1 (fi) |
| MX (1) | MX161088A (fi) |
| NL (1) | NL193217C (fi) |
| SE (1) | SE453388B (fi) |
| ZA (1) | ZA831110B (fi) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1210673B (it) * | 1982-02-26 | 1989-09-20 | Medosan Ind Biochimi | Antinfiammatoria amidi pirrolacetiche ad attivita' |
| US4585784A (en) * | 1983-01-26 | 1986-04-29 | Mcneilab, Inc. | Pyrrole-2-acetylamino acid derivative compounds |
| YU251283A (en) * | 1983-01-26 | 1986-04-30 | Mcneilab Inc | Process for obtaining pyrrol-2-acetylamino acid derivatives |
| IT1197688B (it) * | 1983-07-29 | 1988-12-06 | Medosan Ind Biochimi | Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi |
| US6180658B1 (en) | 1995-07-14 | 2001-01-30 | Medosan Ricerca S.R.L. | Method for counteracting blood platelet aggregation in a patient in need thereof |
| IT1278144B1 (it) * | 1995-07-14 | 1997-11-17 | Medosan Ricerca Srl | Impiego dell'amtolmetineguacil (med 15) come farmaco antisecretivo sulla secrezione gastrica e quindi gastroprotettivo. |
| US5889041A (en) * | 1995-07-14 | 1999-03-30 | Medosan Ricerca S.R.L. | Method for treating an inflammatory pathological condition |
| DK1024807T3 (da) * | 1997-08-08 | 2003-08-04 | Medosan Ricerca Srl | Anvendelse af forbindelsen 2-methoxyphenyl-1-methyl-5p-methylbenzoyl-pyrrol-2-acetamidoacetat for fremstilling af et anti-inflammatorisk medikament med forhindring af gastrisk hypersecernering og forstyrrelse af nyrefunktionen |
| IT1297140B1 (it) * | 1997-12-24 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Forma cristallina del guaiacil estere dell'acido l-metil-5-p-toluoil- pirrol-2-acetammidoacetico, procedimento per la sua preparazione e |
| IT1302898B1 (it) * | 1998-12-03 | 2000-10-10 | Medosan Ricerca Srl | Uso di amtolmetine guacil per la produzione di farmaci ad effettoantiinfiammatorio nelle infiammazioni intestinali. |
| EP1328225B1 (en) | 2000-09-15 | 2010-03-10 | Bruder Healthcare Company | Wound and therapy compress and dressing |
| US10105259B2 (en) | 2000-09-15 | 2018-10-23 | Bruder Healthcare Company, Llc | Wound and therapy compress and dressing |
| US9925087B2 (en) | 2000-09-15 | 2018-03-27 | Bruder Healthcare Company, Llc | Wound and therapy compress and dressing |
| CN100390144C (zh) * | 2006-03-29 | 2008-05-28 | 安徽省庆云医药化工有限公司 | 1-甲基-5-对甲苯酰吡咯-2-乙酰氨基乙酸愈创木酚酯的制备方法 |
| WO2014143139A1 (en) | 2013-03-15 | 2014-09-18 | Bruder Healthcare Company | Wound and therapy compress and dressing |
| US12011388B2 (en) | 2016-03-01 | 2024-06-18 | The Hilsinger Company Parent, Llc | Therapeutic thermal compress with phase-change material |
| USD871598S1 (en) | 2016-11-30 | 2019-12-31 | Bruder Healthcare Company, Llc | Therapeutic eye mask |
| USD844795S1 (en) | 2016-11-30 | 2019-04-02 | Bruder Healthcare Company, Llc | Therapeutic eye mask |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE338993B (fi) * | 1967-07-26 | 1971-09-27 | Mcneilab Inc | |
| US3952012A (en) * | 1970-01-26 | 1976-04-20 | Mcneil Laboratories, Incorporated | Aroyl-substituted pyrroles |
| US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
| US3950012A (en) * | 1975-03-17 | 1976-04-13 | Donovan Robert G | Retainer for multi-leafed devices |
| US4200645A (en) * | 1977-05-10 | 1980-04-29 | Beecham Group Limited | Pyrrole derivatives |
| JPS5524141A (en) * | 1978-08-11 | 1980-02-21 | Sagami Chem Res Center | 1-alkyl-5-(p-toluoyl)-pyrrolyl-2thioacetamide derivative |
| US4396626A (en) * | 1980-10-09 | 1983-08-02 | Beecham Group Limited | Cyclic compounds and their use |
| ES497136A0 (es) * | 1980-11-11 | 1981-10-16 | Calzada & Co | Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico |
| JPS57144256A (en) * | 1981-03-03 | 1982-09-06 | Sagami Chem Res Center | Preparation of (1-alkyl-5-toluoyl-2-pyrrolyl)acetamide derivative |
| IT1137229B (it) * | 1981-05-26 | 1986-09-03 | Poli Ind Chimica Spa | Composto solubile ad attivita' analgesica |
| US4434175A (en) * | 1981-08-10 | 1984-02-28 | Merck & Co., Inc. | Nonsteroidal compounds as anti-inflammatory and analgesic agents |
| IT1210673B (it) * | 1982-02-26 | 1989-09-20 | Medosan Ind Biochimi | Antinfiammatoria amidi pirrolacetiche ad attivita' |
| IT1148117B (it) * | 1982-03-05 | 1986-11-26 | Medosan Ind Biochimi | Attivita'antiflogistica,analgesica,antipiretica,mucolitica e seda tiva della tosse dell'1 metil-5-p-tolilpirrol-2-acetato di 2'metossi-fenile |
| YU251283A (en) * | 1983-01-26 | 1986-04-30 | Mcneilab Inc | Process for obtaining pyrrol-2-acetylamino acid derivatives |
| IT1174773B (it) * | 1983-07-29 | 1987-07-01 | Medosan Ind Biochimi | Attivita' antiaggregante piastrinica e broncolitica della 7-(1-metil-5-p-metilbenzoilpirrol-2-acetamidoetil)teofillina |
| IT1197688B (it) * | 1983-07-29 | 1988-12-06 | Medosan Ind Biochimi | Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi |
-
1982
- 1982-02-26 IT IT8247881A patent/IT1210673B/it active Protection Beyond IP Right Term
-
1983
- 1983-02-15 IE IE310/83A patent/IE54896B1/en not_active IP Right Cessation
- 1983-02-16 IL IL8367929A patent/IL67929A/xx not_active IP Right Cessation
- 1983-02-17 DK DK070083A patent/DK155792C/da not_active IP Right Cessation
- 1983-02-17 CA CA000421878A patent/CA1207769A/en not_active Expired
- 1983-02-18 FI FI830556A patent/FI77227C/fi not_active IP Right Cessation
- 1983-02-18 ZA ZA831110A patent/ZA831110B/xx unknown
- 1983-02-22 DE DE19833306006 patent/DE3306006A1/de active Granted
- 1983-02-23 GR GR70582A patent/GR77920B/el unknown
- 1983-02-23 SE SE8301008A patent/SE453388B/sv not_active IP Right Cessation
- 1983-02-23 GB GB08304996A patent/GB2115417B/en not_active Expired
- 1983-02-24 NL NL8300693A patent/NL193217C/nl not_active IP Right Cessation
- 1983-02-24 LU LU84660A patent/LU84660A1/fr unknown
- 1983-02-24 BE BE0/210207A patent/BE896018A/fr not_active IP Right Cessation
- 1983-02-25 AT AT0067383A patent/AT376204B/de not_active IP Right Cessation
- 1983-02-25 JP JP58031721A patent/JPS58159458A/ja active Granted
- 1983-02-25 CH CH1062/83A patent/CH658650A5/it not_active IP Right Cessation
- 1983-02-25 ES ES520112A patent/ES8403453A1/es not_active Expired
- 1983-02-25 MX MX83196365A patent/MX161088A/es unknown
- 1983-02-26 KR KR1019830000794A patent/KR890004127B1/ko not_active IP Right Cessation
- 1983-02-28 FR FR8303275A patent/FR2522324B1/fr not_active Expired
-
1985
- 1985-02-11 US US06/700,059 patent/US4882349A/en not_active Expired - Lifetime
- 1985-04-30 US US06/728,758 patent/US4578481A/en not_active Expired - Lifetime
-
1991
- 1991-02-27 JP JP3033082A patent/JPH0662562B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL69347A (en) | Methylene-diphosphonic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL69601A0 (en) | Naphthyridine-,quinoline-and benzoxazine-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL67826A0 (en) | Pyrazolooxazines,pyrazolothiazines and pyrazoloquinolines,their preparation and pharmaceutical compositions containing them | |
| DE3468030D1 (en) | 13-alpha-alkyl gonanes, their preparation and pharmaceutical compositions containing them | |
| IL73951A0 (en) | 2-phenyl-imidazoles,their preparation and pharmaceutical compositions containing them | |
| IL71475A0 (en) | N-aryl-alpha-amino-carboxamides,their preparation and pharmaceutical compositions containing them | |
| IL67929A (en) | 1-methyl-5-p-toluoylpyrrole-2-acetic acid amides,their preparation and pharmaceutical compositions comprising them | |
| IL68804A0 (en) | Amides,their manufacture and pharmaceutical compositions containing them | |
| IL68323A0 (en) | Phenoxyalkylcarboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them | |
| IL68497A0 (en) | Benzoazacycloalkyl-spiro-imidazolidines,their preparation and pharmaceutical compositions containing them | |
| IL68586A0 (en) | 4-aryl-4-piperidinecarbinols,their preparation and pharmaceutical compositions containing them | |
| IL68699A (en) | 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them | |
| IL71419A0 (en) | Phenylaminobenzenealkanols,their preparation and pharmaceutical compositions containing them | |
| IL71648A (en) | 5-acyl-2-(1h)-pyridinones,their preparation and pharmaceutical compositions containing them | |
| IL72307A0 (en) | Pyridinyl-2-pyrimidinamines,their preparation and pharmaceutical compositions containing them | |
| IL70158A (en) | Tetrahydronaphthalene-carboxamides,their preparation and pharmaceutical compositions comprising them | |
| IL69407A0 (en) | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them | |
| IL71110A0 (en) | Azolylmethylcycloalkanes,their preparation and pharmaceutical compositions containing them | |
| IL70169A0 (en) | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them | |
| IL71661A0 (en) | 4-phenyl-tetrahydro-furano-pyridines,their preparation and pharmaceutical compositions containing them | |
| IL69172A (en) | Phenylacetic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL71657A0 (en) | Substituted piperazin-1-yl-acetic acid amides,their preparation and pharmaceutical compositions containing them | |
| IL68520A0 (en) | 5-oxo-2-pyrrolidinepropanoic acid and derivatives thereof,their preparation and pharmaceutical compositions containing them | |
| IL69817A (en) | 7-anilinoisoquinoline-5,8-quinones,their preparation and pharmaceutical compositions comprising them | |
| IL69010A (en) | 15-alkoxyimino-14-oxoeburnamenines,their preparation and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |