IL67839A0 - Novel carbacyclins,process for the preparation thereof,and pharmaceutical compositions containing the same - Google Patents
Novel carbacyclins,process for the preparation thereof,and pharmaceutical compositions containing the sameInfo
- Publication number
- IL67839A0 IL67839A0 IL67839A IL6783983A IL67839A0 IL 67839 A0 IL67839 A0 IL 67839A0 IL 67839 A IL67839 A IL 67839A IL 6783983 A IL6783983 A IL 6783983A IL 67839 A0 IL67839 A0 IL 67839A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- same
- pharmaceutical compositions
- compositions containing
- carbacyclins
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- XZFRIPGNUQRGPI-WLPVIMDJSA-N Carbacyclin Chemical class C1\C(=C\CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 XZFRIPGNUQRGPI-WLPVIMDJSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4015—Esters of acyclic unsaturated acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Lubricants (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19823204443 DE3204443A1 (de) | 1982-02-08 | 1982-02-08 | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
IL67839A0 true IL67839A0 (en) | 1983-06-15 |
Family
ID=6155190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL67839A IL67839A0 (en) | 1982-02-08 | 1983-02-06 | Novel carbacyclins,process for the preparation thereof,and pharmaceutical compositions containing the same |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0086404B1 (fr) |
JP (1) | JPH0611728B2 (fr) |
AT (1) | ATE24487T1 (fr) |
AU (1) | AU567867B2 (fr) |
CA (1) | CA1215362A (fr) |
CS (1) | CS235307B2 (fr) |
DD (1) | DD207901A5 (fr) |
DE (2) | DE3204443A1 (fr) |
DK (1) | DK156563C (fr) |
ES (1) | ES519627A0 (fr) |
FI (1) | FI78064C (fr) |
GR (1) | GR77967B (fr) |
HU (1) | HU191197B (fr) |
IE (1) | IE54554B1 (fr) |
IL (1) | IL67839A0 (fr) |
NO (1) | NO155729C (fr) |
NZ (1) | NZ203115A (fr) |
SU (1) | SU1145926A3 (fr) |
ZA (1) | ZA83851B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3225287A1 (de) * | 1982-07-02 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3408699A1 (de) * | 1984-03-08 | 1985-09-12 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US4927963A (en) * | 1989-04-28 | 1990-05-22 | Syntex (U.S.A.) Inc. | Novel processes for the synthesis of certain bicyclo(4.2.0)octane derivatives with valuable therapeutic properties |
DE4135193C1 (fr) * | 1991-10-22 | 1993-03-11 | Schering Ag Berlin Und Bergkamen, 1000 Berlin, De |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2845770A1 (de) * | 1978-10-19 | 1980-04-30 | Schering Ag | Neue prostacyclin-derivate und verfahren zu ihrer herstellung |
CA1201712A (fr) * | 1980-02-28 | 1986-03-11 | Paul A. Aristoff | Analogues de la carbacycline |
DE3104044A1 (de) * | 1981-02-02 | 1982-08-26 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue prostacyclin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1982
- 1982-02-08 DE DE19823204443 patent/DE3204443A1/de not_active Withdrawn
-
1983
- 1983-01-17 SU SU833534779A patent/SU1145926A3/ru active
- 1983-01-28 NZ NZ203115A patent/NZ203115A/en unknown
- 1983-02-03 AT AT83101008T patent/ATE24487T1/de active
- 1983-02-03 EP EP83101008A patent/EP0086404B1/fr not_active Expired
- 1983-02-03 DE DE8383101008T patent/DE3368609D1/de not_active Expired
- 1983-02-04 DD DD83247723A patent/DD207901A5/de not_active IP Right Cessation
- 1983-02-06 IL IL67839A patent/IL67839A0/xx not_active IP Right Cessation
- 1983-02-07 FI FI830414A patent/FI78064C/fi not_active IP Right Cessation
- 1983-02-07 JP JP58017584A patent/JPH0611728B2/ja not_active Expired - Lifetime
- 1983-02-07 CA CA000421004A patent/CA1215362A/fr not_active Expired
- 1983-02-07 HU HU83412A patent/HU191197B/hu not_active IP Right Cessation
- 1983-02-07 CS CS83847A patent/CS235307B2/cs unknown
- 1983-02-07 GR GR70438A patent/GR77967B/el unknown
- 1983-02-07 AU AU11180/83A patent/AU567867B2/en not_active Ceased
- 1983-02-07 NO NO830399A patent/NO155729C/no unknown
- 1983-02-08 IE IE246/83A patent/IE54554B1/en not_active IP Right Cessation
- 1983-02-08 ZA ZA83851A patent/ZA83851B/xx unknown
- 1983-02-08 DK DK052383A patent/DK156563C/da not_active IP Right Cessation
- 1983-02-08 ES ES519627A patent/ES519627A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
DK52383D0 (da) | 1983-02-08 |
DK52383A (da) | 1983-08-09 |
ES8400384A1 (es) | 1983-11-16 |
NO155729C (no) | 1987-05-20 |
ES519627A0 (es) | 1983-11-16 |
FI78064C (fi) | 1989-06-12 |
CA1215362A (fr) | 1986-12-16 |
AU567867B2 (en) | 1987-12-10 |
NO830399L (no) | 1983-08-09 |
EP0086404B1 (fr) | 1986-12-30 |
EP0086404A1 (fr) | 1983-08-24 |
DE3368609D1 (en) | 1987-02-05 |
IE54554B1 (en) | 1989-11-22 |
AU1118083A (en) | 1983-08-18 |
FI78064B (fi) | 1989-02-28 |
FI830414A0 (fi) | 1983-02-07 |
CS235307B2 (en) | 1985-05-15 |
ATE24487T1 (de) | 1987-01-15 |
SU1145926A3 (ru) | 1985-03-15 |
NO155729B (no) | 1987-02-09 |
GR77967B (fr) | 1984-09-25 |
HU191197B (en) | 1987-01-28 |
IE830246L (en) | 1983-08-08 |
DD207901A5 (de) | 1984-03-21 |
DK156563C (da) | 1990-01-29 |
JPS58146531A (ja) | 1983-09-01 |
NZ203115A (en) | 1986-03-14 |
DK156563B (da) | 1989-09-11 |
JPH0611728B2 (ja) | 1994-02-16 |
FI830414L (fi) | 1983-08-09 |
DE3204443A1 (de) | 1983-08-18 |
ZA83851B (en) | 1983-10-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2036876A1 (fr) | Derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
IL64905A (en) | Process for the preparation of 2-penems,carbapenems,carbacephams,oxapenems,and azapenems,some novel such compounds and pharmaceutical compositions containing them | |
EP0150937A3 (en) | Dihydropyridazinones | |
MY100095A (en) | 2-oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition. | |
AU580728B2 (en) | Novel carbacyclins, process for their manufacture and their use as medicaments | |
HUT40101A (en) | Process for producing quinolin-carboxylic acid derivatives and pharmaceutical compositions containing them as active agents | |
IE872588L (en) | Compounds | |
DE3477488D1 (en) | Polymethoxybenzyl piperazine derivatives, processes for their preparation and pharmaceutical compositions containing said derivatives | |
DE3362504D1 (en) | 1-carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use | |
IL67839A0 (en) | Novel carbacyclins,process for the preparation thereof,and pharmaceutical compositions containing the same | |
JPS55141478A (en) | Phenylpiperazine derivative*its manufacture and its composition | |
DE3465085D1 (en) | Derivatives of 4-(3-alkynyloxy-2-hydroxy-propyl)-piperazin-1-yl-n-phenyl acetamide, their preparation and their therapeutical use | |
GB8515212D0 (en) | Thiazolidine derivatives | |
HUT45059A (en) | Process for producing abeoergoline derivatives | |
ES464753A1 (es) | Procedimiento para producir nuevos derivados 6-sustituidos de d-8-ergolin-i-ilacetamida. | |
MY103509A (en) | Indole derivatives. | |
MY101746A (en) | 1,5-benzothiazepine derivatives, a process for preparing the same, pharmaceutical compositions as well as the use thereof. | |
ES8307812A1 (es) | Un procedimiento para la preparacion de nuevos amidin derivados del acido clavulawilo. | |
ES8506313A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 7-oxo-1-azabiciclo(3.2.0)hepteno. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |