IL67496A - Substituted alkylaminopyrimidine(thi)ones,their preparation and pharmaceutical compositions containing them for treatment of ulcers - Google Patents
Substituted alkylaminopyrimidine(thi)ones,their preparation and pharmaceutical compositions containing them for treatment of ulcersInfo
- Publication number
- IL67496A IL67496A IL67496A IL6749682A IL67496A IL 67496 A IL67496 A IL 67496A IL 67496 A IL67496 A IL 67496A IL 6749682 A IL6749682 A IL 6749682A IL 67496 A IL67496 A IL 67496A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- substituted
- alkylaminopyrimidine
- thi
- ulcers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33478481A | 1981-12-28 | 1981-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL67496A true IL67496A (en) | 1986-11-30 |
Family
ID=23308823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL67496A IL67496A (en) | 1981-12-28 | 1982-12-16 | Substituted alkylaminopyrimidine(thi)ones,their preparation and pharmaceutical compositions containing them for treatment of ulcers |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0083186B1 (ja) |
| JP (1) | JPS58118585A (ja) |
| KR (1) | KR860000106B1 (ja) |
| AT (1) | ATE34173T1 (ja) |
| AU (1) | AU558153B2 (ja) |
| CA (1) | CA1206151A (ja) |
| CS (1) | CS235976B2 (ja) |
| DD (1) | DD203720A5 (ja) |
| DE (1) | DE3278473D1 (ja) |
| DK (1) | DK574782A (ja) |
| ES (1) | ES518592A0 (ja) |
| FI (1) | FI824407L (ja) |
| GB (1) | GB2111995B (ja) |
| GR (1) | GR78415B (ja) |
| HU (1) | HU192951B (ja) |
| IE (1) | IE54313B1 (ja) |
| IL (1) | IL67496A (ja) |
| NZ (1) | NZ202797A (ja) |
| PH (1) | PH19797A (ja) |
| PL (1) | PL239796A1 (ja) |
| PT (1) | PT76004B (ja) |
| SU (1) | SU1195906A3 (ja) |
| ZA (1) | ZA829247B (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4468399A (en) * | 1981-12-28 | 1984-08-28 | Eli Lilly And Company | 2-[2-(2-Aminoalkyl-4-thiazolylmethylthio)alkyl]-amino-5-substituted-4-pyrimidones |
| GB8320505D0 (en) * | 1983-07-29 | 1983-09-01 | Smith Kline French Lab | Chemical compounds |
| US4772704A (en) * | 1983-09-21 | 1988-09-20 | Bristol-Myers Company | 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity |
| GB8421427D0 (en) * | 1984-08-23 | 1984-09-26 | Smith Kline French Lab | Chemical compounds |
| CN102260254A (zh) * | 2010-05-31 | 2011-11-30 | 中国农业科学院植物保护研究所 | 新颖2-硝基亚氨基嘧啶衍生物的合成 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1421792A (en) * | 1973-05-17 | 1976-01-21 | Smith Kline French Lab | Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them |
| IN146736B (ja) * | 1975-10-02 | 1979-08-25 | Smith Kline French Lab | |
| US4200578A (en) * | 1978-12-18 | 1980-04-29 | Bristol-Myers Company | Thiazole derivatives |
| US4521418A (en) * | 1979-02-21 | 1985-06-04 | Smith Kline & French Laboratories Limited | Guanidinothiazolyl derivatives |
| AU531142B2 (en) * | 1979-04-04 | 1983-08-11 | Smith Kline & French Laboratories Limited | 2 amino- pyimindones |
| US4375547A (en) * | 1980-10-02 | 1983-03-01 | Eli Lilly And Company | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
-
1982
- 1982-12-14 CA CA000417662A patent/CA1206151A/en not_active Expired
- 1982-12-14 NZ NZ202797A patent/NZ202797A/en unknown
- 1982-12-15 AU AU91539/82A patent/AU558153B2/en not_active Ceased
- 1982-12-15 ZA ZA829247A patent/ZA829247B/xx unknown
- 1982-12-15 PH PH28281A patent/PH19797A/en unknown
- 1982-12-16 IL IL67496A patent/IL67496A/xx unknown
- 1982-12-20 EP EP82306785A patent/EP0083186B1/en not_active Expired
- 1982-12-20 DE DE8282306785T patent/DE3278473D1/de not_active Expired
- 1982-12-20 PT PT76004A patent/PT76004B/pt unknown
- 1982-12-20 AT AT82306785T patent/ATE34173T1/de active
- 1982-12-20 GB GB08236116A patent/GB2111995B/en not_active Expired
- 1982-12-21 IE IE3031/82A patent/IE54313B1/en unknown
- 1982-12-21 CS CS829474A patent/CS235976B2/cs unknown
- 1982-12-21 FI FI824407A patent/FI824407L/fi not_active Application Discontinuation
- 1982-12-23 GR GR70164A patent/GR78415B/el unknown
- 1982-12-24 SU SU823526201A patent/SU1195906A3/ru active
- 1982-12-27 ES ES518592A patent/ES518592A0/es active Granted
- 1982-12-27 HU HU824173A patent/HU192951B/hu not_active IP Right Cessation
- 1982-12-27 DK DK574782A patent/DK574782A/da not_active Application Discontinuation
- 1982-12-28 JP JP57234881A patent/JPS58118585A/ja active Pending
- 1982-12-28 KR KR8205837A patent/KR860000106B1/ko active
- 1982-12-28 PL PL23979682A patent/PL239796A1/xx unknown
- 1982-12-28 DD DD82246677A patent/DD203720A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA829247B (en) | 1984-07-25 |
| AU558153B2 (en) | 1987-01-22 |
| GR78415B (ja) | 1984-09-27 |
| KR840002831A (ko) | 1984-07-21 |
| CA1206151A (en) | 1986-06-17 |
| EP0083186B1 (en) | 1988-05-11 |
| IE54313B1 (en) | 1989-08-16 |
| DD203720A5 (de) | 1983-11-02 |
| DK574782A (da) | 1983-06-29 |
| PL239796A1 (en) | 1984-05-21 |
| SU1195906A3 (ru) | 1985-11-30 |
| JPS58118585A (ja) | 1983-07-14 |
| ES8403895A1 (es) | 1984-04-01 |
| FI824407L (fi) | 1983-06-29 |
| EP0083186A2 (en) | 1983-07-06 |
| ATE34173T1 (de) | 1988-05-15 |
| NZ202797A (en) | 1985-08-30 |
| IE823031L (en) | 1983-06-28 |
| HU192951B (en) | 1987-08-28 |
| GB2111995A (en) | 1983-07-13 |
| DE3278473D1 (en) | 1988-06-16 |
| FI824407A0 (fi) | 1982-12-21 |
| KR860000106B1 (ko) | 1986-02-19 |
| GB2111995B (en) | 1985-07-24 |
| PT76004A (en) | 1983-01-01 |
| PT76004B (en) | 1985-12-03 |
| PH19797A (en) | 1986-07-02 |
| EP0083186A3 (en) | 1984-05-23 |
| CS235976B2 (en) | 1985-05-15 |
| AU9153982A (en) | 1983-07-07 |
| ES518592A0 (es) | 1984-04-01 |
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