IL65852A - 2-aminoalkylenethioquinoline derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

2-aminoalkylenethioquinoline derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL65852A
IL65852A IL65852A IL6585282A IL65852A IL 65852 A IL65852 A IL 65852A IL 65852 A IL65852 A IL 65852A IL 6585282 A IL6585282 A IL 6585282A IL 65852 A IL65852 A IL 65852A
Authority
IL
Israel
Prior art keywords
aminoalkylenethioquinoline
derivatives
preparation
pharmaceutical compositions
pharmaceutical
Prior art date
Application number
IL65852A
Other languages
English (en)
Other versions
IL65852A0 (en
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of IL65852A0 publication Critical patent/IL65852A0/xx
Publication of IL65852A publication Critical patent/IL65852A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
IL65852A 1981-06-09 1982-05-23 2-aminoalkylenethioquinoline derivatives,their preparation and pharmaceutical compositions comprising them IL65852A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8117642 1981-06-09

Publications (2)

Publication Number Publication Date
IL65852A0 IL65852A0 (en) 1982-08-31
IL65852A true IL65852A (en) 1986-04-29

Family

ID=10522379

Family Applications (1)

Application Number Title Priority Date Filing Date
IL65852A IL65852A (en) 1981-06-09 1982-05-23 2-aminoalkylenethioquinoline derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (25)

Country Link
US (1) US4435405A (el)
EP (1) EP0066993B1 (el)
JP (1) JPS58965A (el)
AR (1) AR230437A1 (el)
AT (1) ATE11534T1 (el)
AU (1) AU556719B2 (el)
CA (1) CA1189077A (el)
CS (1) CS238624B2 (el)
DE (1) DE3262122D1 (el)
DK (1) DK152428C (el)
ES (3) ES8401034A1 (el)
FI (1) FI77451C (el)
GR (1) GR76452B (el)
HU (1) HU186523B (el)
IE (1) IE53064B1 (el)
IL (1) IL65852A (el)
IN (1) IN158970B (el)
NO (1) NO161066C (el)
NZ (1) NZ200878A (el)
PH (1) PH18503A (el)
PL (1) PL135871B1 (el)
PT (1) PT75024B (el)
SU (1) SU1192618A3 (el)
YU (2) YU43269B (el)
ZA (1) ZA823586B (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE27152T1 (de) * 1982-04-07 1987-05-15 Ici Plc Chinolin-derivate.
EP0093521B1 (en) * 1982-05-04 1988-08-24 Imperial Chemical Industries Plc Quinoline derivatives
US4585866A (en) * 1982-06-09 1986-04-29 Merrell Dow Pharmaceuticals Inc. Treatment of migraine with substituted tropyl benzoate derivatives
GB8308601D0 (en) * 1983-03-29 1983-05-05 Ici Plc Heterocyclic compounds
JPS60166406A (ja) * 1984-02-09 1985-08-29 株式会社イナックス 乾式プレス装置の坏土充填方法
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
JP2733511B2 (ja) * 1988-10-22 1998-03-30 日本臓器製薬株式会社 新規アミノアルカン誘導体
JPH03147803A (ja) * 1989-11-06 1991-06-24 Tiger Mach Seisakusho:Kk 表面多色変化模様のあるコンクリートブロックの製造方法
FR2795645B1 (fr) * 1999-06-30 2001-09-21 Union Pharma Scient Appl Nouvelle association pharmaceutique a activite analgesique
US6566361B2 (en) 1999-06-30 2003-05-20 Laboratories, Upsa Azapirone pain treatment
EP1216988A4 (en) * 1999-09-28 2005-04-20 Nihon Nohyaku Co Ltd THIOALKYLAMINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
FR2810664B1 (fr) * 2000-06-27 2004-12-24 Adir Nouveaux composes cyclopropaniques 1,1 et 1,2-dissubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
EP2129378B1 (en) 2007-02-28 2011-06-01 Thromboserin Limited Therapeutic compositions comprising thromboserin or a salt thereof for use in the prevention or treatment of thrombosis in a patient at risk of bleeding
WO2009082268A2 (ru) 2007-12-21 2009-07-02 Alla Chem, Llc ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1049379B (de) 1959-01-29 Farbenfabriken Bayer Aktiengesellschaft, Leverkusen-Bayerwerk Verfahren zur Herstellung von 4 - (tert.-Aminoalkylmercapto)chinolinverbindungen
DE430960C (de) 1924-07-11 1926-06-23 J G Farbenindustrie Akt Ges Verfahren zur Darstellung von basischen AEthern von Chinolinderivaten
US1572768A (en) 1925-06-26 1926-02-09 Winthrop Chem Co Inc Pharmaceutical product
US1860286A (en) 1929-05-16 1932-05-24 Soc Of Chemical Ind Basic ethers of aryl-quinolines
GB1511390A (en) * 1975-12-04 1978-05-17 Pfizer Ltd Imidazolylalkyl sulphide antifungal agents
US4343805A (en) 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds

Also Published As

Publication number Publication date
PL135871B1 (en) 1985-12-31
YU188284A (en) 1985-10-31
FI821965A0 (fi) 1982-06-02
EP0066993B1 (en) 1985-01-30
NO161066B (no) 1989-03-20
IL65852A0 (en) 1982-08-31
NO161066C (no) 1989-06-28
FI77451B (fi) 1988-11-30
ES8402576A1 (es) 1984-02-01
IE821243L (en) 1982-12-09
ES512960A0 (es) 1983-12-01
IE53064B1 (en) 1988-05-25
DK257782A (da) 1982-12-10
CS238624B2 (en) 1985-12-16
IN158970B (el) 1987-02-28
PL236836A1 (en) 1983-09-12
AU8386382A (en) 1982-12-16
FI77451C (fi) 1989-03-10
ES8502688A1 (es) 1985-01-16
PT75024A (en) 1982-07-01
YU42905B (en) 1988-12-31
CA1189077A (en) 1985-06-18
NZ200878A (en) 1985-02-28
ZA823586B (en) 1983-03-30
PH18503A (en) 1985-08-02
JPH0424349B2 (el) 1992-04-24
CS425382A2 (en) 1984-02-13
NO821904L (no) 1982-12-10
YU43269B (en) 1989-06-30
US4435405A (en) 1984-03-06
JPS58965A (ja) 1983-01-06
HU186523B (en) 1985-08-28
GR76452B (el) 1984-08-10
DE3262122D1 (en) 1985-03-14
ATE11534T1 (de) 1985-02-15
PT75024B (en) 1984-05-08
DK152428B (da) 1988-02-29
ES519006A0 (es) 1984-02-01
YU123282A (en) 1985-04-30
ES8401034A1 (es) 1983-12-01
AR230437A1 (es) 1984-04-30
AU556719B2 (en) 1986-11-13
SU1192618A3 (ru) 1985-11-15
DK152428C (da) 1988-08-15
EP0066993A1 (en) 1982-12-15
ES525298A0 (es) 1985-01-16

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Legal Events

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