IL63964A - 7-(2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido)-3-((2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-ene-2-carboxylic acid and its derivatives,their preparation and pharmacutical compositions containing them and intermediates therefor - Google Patents

7-(2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido)-3-((2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-ene-2-carboxylic acid and its derivatives,their preparation and pharmacutical compositions containing them and intermediates therefor

Info

Publication number
IL63964A
IL63964A IL63964A IL6396481A IL63964A IL 63964 A IL63964 A IL 63964A IL 63964 A IL63964 A IL 63964A IL 6396481 A IL6396481 A IL 6396481A IL 63964 A IL63964 A IL 63964A
Authority
IL
Israel
Prior art keywords
methyl
oxo
triazin
dihydro
hydroxy
Prior art date
Application number
IL63964A
Other languages
English (en)
Other versions
IL63964A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL63964A0 publication Critical patent/IL63964A0/xx
Publication of IL63964A publication Critical patent/IL63964A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
IL63964A 1980-10-06 1981-09-28 7-(2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido)-3-((2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-ene-2-carboxylic acid and its derivatives,their preparation and pharmacutical compositions containing them and intermediates therefor IL63964A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH745080 1980-10-06

Publications (2)

Publication Number Publication Date
IL63964A0 IL63964A0 (en) 1981-12-31
IL63964A true IL63964A (en) 1984-12-31

Family

ID=4325316

Family Applications (1)

Application Number Title Priority Date Filing Date
IL63964A IL63964A (en) 1980-10-06 1981-09-28 7-(2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido)-3-((2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-ene-2-carboxylic acid and its derivatives,their preparation and pharmacutical compositions containing them and intermediates therefor

Country Status (21)

Country Link
US (3) US4412070A (fi)
EP (1) EP0049499B1 (fi)
JP (3) JPS5791989A (fi)
KR (1) KR870000828B1 (fi)
AT (1) ATE17729T1 (fi)
AU (1) AU554552B2 (fi)
CA (1) CA1168227A (fi)
DE (1) DE3173642D1 (fi)
DK (1) DK379581A (fi)
ES (1) ES8206534A1 (fi)
FI (1) FI73442C (fi)
GR (1) GR75072B (fi)
HU (1) HU185963B (fi)
IE (1) IE51633B1 (fi)
IL (1) IL63964A (fi)
MC (1) MC1421A1 (fi)
NO (2) NO813375L (fi)
NZ (1) NZ198507A (fi)
PH (1) PH20367A (fi)
PT (1) PT73764B (fi)
ZA (1) ZA816741B (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695565A (en) * 1984-10-04 1987-09-22 Merck & Co., Inc. Antibacterial 7β-heterocyclic-cephem
EP0185220A3 (de) * 1984-12-19 1987-09-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Zwischenprodukte zur Herstellung von Cephalosporinen
JP2620743B2 (ja) * 1992-12-02 1997-06-18 株式会社山一屋 垣形成用支柱

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348518A (en) * 1974-05-05 1982-09-07 Hoffmann-La Roche Inc. Cephalosporins
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS5444695A (en) * 1977-09-13 1979-04-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid and its salt and their preparation
US4200745A (en) * 1977-12-20 1980-04-29 Eli Lilly And Company 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
CH641468A5 (de) * 1978-05-30 1984-02-29 Hoffmann La Roche Cephemderivate.
NL8100089A (nl) * 1980-01-17 1981-08-17 Rhone Poulenc Ind Nieuwe thiolen en de bereiding daarvan.

Also Published As

Publication number Publication date
JPH0333159B2 (fi) 1991-05-16
IE812315L (en) 1982-04-06
NO813375L (no) 1982-04-07
PH20367A (en) 1986-12-04
EP0049499A2 (de) 1982-04-14
US4520195A (en) 1985-05-28
NO822876L (no) 1982-04-07
CA1168227A (en) 1984-05-29
MC1421A1 (fr) 1982-10-18
GR75072B (fi) 1984-07-13
FI73442B (fi) 1987-06-30
FI73442C (fi) 1987-10-09
AU7574181A (en) 1982-04-22
ATE17729T1 (de) 1986-02-15
ES506022A0 (es) 1982-08-16
JPH0786112B2 (ja) 1995-09-20
US4412070A (en) 1983-10-25
ZA816741B (en) 1982-09-29
NZ198507A (en) 1985-02-28
US4774330A (en) 1988-09-27
AU554552B2 (en) 1986-08-28
KR830007691A (ko) 1983-11-04
FI813088L (fi) 1982-04-07
PT73764B (en) 1983-10-14
JPS61178993A (ja) 1986-08-11
IL63964A0 (en) 1981-12-31
JPS6146478B2 (fi) 1986-10-14
EP0049499B1 (de) 1986-01-29
PT73764A (en) 1981-11-01
JPS5791989A (en) 1982-06-08
HU185963B (en) 1985-04-28
ES8206534A1 (es) 1982-08-16
KR870000828B1 (ko) 1987-04-23
DK379581A (da) 1982-04-07
JPH03264591A (ja) 1991-11-25
DE3173642D1 (en) 1986-03-13
IE51633B1 (en) 1987-01-21
EP0049499A3 (en) 1983-09-07

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