IL63075A - 23-demycinosyltylosin-and 20-dihydro-23-demycinosyltylosin antibiotics,process and microorganisms for their preparation and veterinary compositions containing them - Google Patents
23-demycinosyltylosin-and 20-dihydro-23-demycinosyltylosin antibiotics,process and microorganisms for their preparation and veterinary compositions containing themInfo
- Publication number
- IL63075A IL63075A IL63075A IL6307581A IL63075A IL 63075 A IL63075 A IL 63075A IL 63075 A IL63075 A IL 63075A IL 6307581 A IL6307581 A IL 6307581A IL 63075 A IL63075 A IL 63075A
- Authority
- IL
- Israel
- Prior art keywords
- demycinosyltylosin
- dihydro
- antibiotics
- microorganisms
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/54—Streptomyces fradiae
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/156,855 US4321362A (en) | 1980-06-12 | 1980-06-12 | De(mycinosyloxy)tylosin and process for its production |
US06/156,854 US4321361A (en) | 1980-06-12 | 1980-06-12 | Demycinosyltylosin and process for its production |
Publications (2)
Publication Number | Publication Date |
---|---|
IL63075A0 IL63075A0 (en) | 1981-09-13 |
IL63075A true IL63075A (en) | 1984-07-31 |
Family
ID=26853578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL63075A IL63075A (en) | 1980-06-12 | 1981-06-11 | 23-demycinosyltylosin-and 20-dihydro-23-demycinosyltylosin antibiotics,process and microorganisms for their preparation and veterinary compositions containing them |
Country Status (26)
Country | Link |
---|---|
US (2) | US4321361A (xx) |
EP (1) | EP0042250B1 (xx) |
JP (1) | JPS5731699A (xx) |
KR (1) | KR840001956B1 (xx) |
AR (2) | AR227316A1 (xx) |
AU (1) | AU544988B2 (xx) |
CA (1) | CA1172189A (xx) |
CS (1) | CS225841B2 (xx) |
DD (1) | DD159644A5 (xx) |
DE (1) | DE3162500D1 (xx) |
DK (1) | DK255681A (xx) |
ES (1) | ES502980A0 (xx) |
FI (1) | FI811826L (xx) |
GB (1) | GB2077731B (xx) |
GR (1) | GR75277B (xx) |
HU (1) | HU189512B (xx) |
IE (1) | IE51614B1 (xx) |
IL (1) | IL63075A (xx) |
NZ (1) | NZ197359A (xx) |
PH (1) | PH16171A (xx) |
PL (2) | PL131731B1 (xx) |
PT (1) | PT73165B (xx) |
RO (1) | RO81016A (xx) |
SU (1) | SU1151218A3 (xx) |
YU (1) | YU144381A (xx) |
ZA (1) | ZA813579B (xx) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4486584A (en) * | 1980-07-15 | 1984-12-04 | Eli Lilly And Company | Demethylmacrocin compounds and derivatives thereof |
US4419508A (en) * | 1980-11-10 | 1983-12-06 | Eli Lilly And Company | 20-Dihydro-20-deoxy-23-demycinosyltylosin and process for its production |
US4487923A (en) * | 1981-12-14 | 1984-12-11 | Eli Lilly And Company | Method of preparing 23-monoesters of OMT and DMT |
US4396613A (en) * | 1981-12-14 | 1983-08-02 | Eli Lilly And Company | 23-Ester derivatives of DMT and method of using same |
US4401660A (en) * | 1981-12-14 | 1983-08-30 | Eli Lilly And Company | Ester derivatives of 5-O-mycaminosyl tylonolide and method of using same |
US4436733A (en) | 1982-03-03 | 1984-03-13 | Eli Lilly And Company | 4"- And 3-ester derivatives of DMT and DMOT |
US4435388A (en) | 1982-06-10 | 1984-03-06 | Schering Corporation | Tylosin 20-imino-20-deoxo-4"-acyl derivatives, pharmaceutical compositions and method of use |
JPS58219197A (ja) * | 1982-06-15 | 1983-12-20 | Sanraku Inc | マクロライド系抗生物質の誘導体 |
US4436729A (en) | 1982-06-30 | 1984-03-13 | Schering Corporation | 23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use |
US4528369A (en) * | 1982-07-02 | 1985-07-09 | Eli Lilly And Company | 20-Dihydro-20-deoxy-23-de(mycinosyloxy)tylosin |
US4459290A (en) * | 1982-07-19 | 1984-07-10 | Eli Lilly And Company | C-23-Modified derivatives of OMT, pharmaceutical compositions and method of use |
US4452784A (en) * | 1982-07-19 | 1984-06-05 | Eli Lilly And Company | C-23-Modified derivatives of DMT |
US4820695A (en) * | 1982-09-13 | 1989-04-11 | Eli Lilly And Company | C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics |
US4443436A (en) | 1982-09-13 | 1984-04-17 | Eli Lilly And Company | C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin |
US4468511A (en) * | 1983-02-28 | 1984-08-28 | Eli Lilly And Company | C-20- And C-23-Modified macrolide derivatives |
IL71032A0 (en) * | 1983-02-28 | 1984-05-31 | Lilly Co Eli | C-20 and c-23-modified macrolide derivatives |
US4629786A (en) * | 1983-02-28 | 1986-12-16 | Eli Lilly And Company | C-20- and C-23 modified macrolide derivatives |
JPS59181294A (ja) * | 1983-03-30 | 1984-10-15 | Satoshi Omura | 抗生物質ptl−448とその誘導体およびそれらの製造方法 |
US4851518A (en) * | 1985-12-23 | 1989-07-25 | Schering Corporation | Di and tri-O-acetyl-"O-iso-valeryl-23-O-demycinosyl tylosins, hydrazone derivatives thereof and processes for their preparation |
US4808575A (en) * | 1986-06-23 | 1989-02-28 | Schering Corporation | 12,13-oxoderivatives of macrolides |
US4962146A (en) * | 1987-04-29 | 1990-10-09 | Schering Corporation | 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives |
JPH01230559A (ja) * | 1988-03-11 | 1989-09-14 | Sagami Chem Res Center | 5−置換メチリデンヒダントイン誘導体 |
IL98599A (en) * | 1990-06-28 | 1995-06-29 | Merck & Co Inc | Stable salts of "4-deoxy-" 4-epi-methylamino abramectin and insecticides containing them |
US7247617B2 (en) * | 2004-07-13 | 2007-07-24 | Kosan Biosciences Incorporated | Sixteen-member macrolide antiinfective agents |
US7378508B2 (en) * | 2007-01-22 | 2008-05-27 | Optimer Pharmaceuticals, Inc. | Polymorphic crystalline forms of tiacumicin B |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3178341A (en) * | 1960-06-27 | 1965-04-13 | Lilly Co Eli | Antibiotics tylosin and desmycosin and derivatives thereof |
US3326759A (en) * | 1962-07-19 | 1967-06-20 | Lilly Co Eli | Antibiotics macrocin and lactenocin |
US3344024A (en) * | 1963-04-17 | 1967-09-26 | American Cyanamid Co | Antibiotic am-684 and method of production |
BE667952A (xx) * | 1964-08-05 | |||
US4161523A (en) * | 1972-11-15 | 1979-07-17 | Schering Corporation | Rosamicin esters, acid addition salts and methods for production thereof |
US3923784A (en) * | 1973-09-10 | 1975-12-02 | Hoffmann La Roche | Erythromycin a derivatives |
YU35363B (en) * | 1974-01-14 | 1980-12-31 | Pliva Zagreb | Process for obtaining n-(benzene-sulfonyl)-5-0desosaminyl-erythromycilamine derivatives |
JPS52139088A (en) * | 1976-05-15 | 1977-11-19 | Sanraku Inc | Antibiotics tyrocin derivatives and their preparation |
US4056616A (en) * | 1976-03-05 | 1977-11-01 | Schering Corporation | Rosamicin derivatives and method of using same |
JPS5315160A (en) * | 1976-07-27 | 1978-02-10 | Nippon Steel Corp | Sensitivity controller of self-scan image sensor in thermal radiating object measuring apparatus |
GB1587685A (en) * | 1977-03-09 | 1981-04-08 | Microbial Chem Res Found | Macrolactone derivatives and their production |
US4205163A (en) * | 1977-11-08 | 1980-05-27 | Sanraku-Ocean Co., Ltd. | Tylosin derivatives |
JPS6016960B2 (ja) * | 1978-09-20 | 1985-04-30 | メルシャン株式会社 | マクロライド系抗生物質n−1及びその製造法 |
-
1980
- 1980-06-12 US US06/156,854 patent/US4321361A/en not_active Expired - Lifetime
- 1980-06-12 US US06/156,855 patent/US4321362A/en not_active Expired - Lifetime
-
1981
- 1981-05-27 ZA ZA00813579A patent/ZA813579B/xx unknown
- 1981-06-09 NZ NZ197359A patent/NZ197359A/en unknown
- 1981-06-09 CA CA000379320A patent/CA1172189A/en not_active Expired
- 1981-06-09 AU AU71446/81A patent/AU544988B2/en not_active Ceased
- 1981-06-09 AR AR285643A patent/AR227316A1/es active
- 1981-06-09 SU SU813345998A patent/SU1151218A3/ru active
- 1981-06-09 PT PT73165A patent/PT73165B/pt unknown
- 1981-06-09 RO RO81104537A patent/RO81016A/ro unknown
- 1981-06-09 AR AR285642A patent/AR226899A1/es active
- 1981-06-09 PH PH25731A patent/PH16171A/en unknown
- 1981-06-09 YU YU01443/81A patent/YU144381A/xx unknown
- 1981-06-10 PL PL1981231594A patent/PL131731B1/pl unknown
- 1981-06-10 EP EP81302571A patent/EP0042250B1/en not_active Expired
- 1981-06-10 DE DE8181302571T patent/DE3162500D1/de not_active Expired
- 1981-06-10 CS CS814338A patent/CS225841B2/cs unknown
- 1981-06-10 PL PL1981231598A patent/PL131733B1/pl unknown
- 1981-06-10 GB GB8117839A patent/GB2077731B/en not_active Expired
- 1981-06-11 FI FI811826A patent/FI811826L/fi not_active Application Discontinuation
- 1981-06-11 JP JP9072581A patent/JPS5731699A/ja active Pending
- 1981-06-11 GR GR65217A patent/GR75277B/el unknown
- 1981-06-11 ES ES502980A patent/ES502980A0/es active Granted
- 1981-06-11 IL IL63075A patent/IL63075A/xx unknown
- 1981-06-11 DK DK255681A patent/DK255681A/da not_active Application Discontinuation
- 1981-06-11 HU HU811737A patent/HU189512B/hu unknown
- 1981-06-11 IE IE1297/81A patent/IE51614B1/en unknown
- 1981-06-12 KR KR1019810002107A patent/KR840001956B1/ko active
- 1981-06-12 DD DD81230761A patent/DD159644A5/de unknown
Also Published As
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