IL61332A - 1 alpha-methyl-17 alpha-alkyl-5 alpha-androstanes,pharmaceutical preparations containing them and process for their manufacture - Google Patents

1 alpha-methyl-17 alpha-alkyl-5 alpha-androstanes,pharmaceutical preparations containing them and process for their manufacture

Info

Publication number
IL61332A
IL61332A IL61332A IL6133280A IL61332A IL 61332 A IL61332 A IL 61332A IL 61332 A IL61332 A IL 61332A IL 6133280 A IL6133280 A IL 6133280A IL 61332 A IL61332 A IL 61332A
Authority
IL
Israel
Prior art keywords
alpha
alkyl
alkenyl
androstanes
methyl
Prior art date
Application number
IL61332A
Other languages
English (en)
Other versions
IL61332A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL61332A0 publication Critical patent/IL61332A0/xx
Publication of IL61332A publication Critical patent/IL61332A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/006Ketals at position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0044Alkenyl derivatives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
IL61332A 1979-10-26 1980-10-23 1 alpha-methyl-17 alpha-alkyl-5 alpha-androstanes,pharmaceutical preparations containing them and process for their manufacture IL61332A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792943776 DE2943776A1 (de) 1979-10-26 1979-10-26 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IL61332A0 IL61332A0 (en) 1980-12-31
IL61332A true IL61332A (en) 1985-05-31

Family

ID=6084722

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61332A IL61332A (en) 1979-10-26 1980-10-23 1 alpha-methyl-17 alpha-alkyl-5 alpha-androstanes,pharmaceutical preparations containing them and process for their manufacture

Country Status (23)

Country Link
US (4) US4344941A (da)
EP (1) EP0027961B1 (da)
JP (1) JPS5673097A (da)
AT (1) ATE2221T1 (da)
AU (1) AU532515B2 (da)
CA (1) CA1160216A (da)
CS (1) CS228507B2 (da)
DD (1) DD153694A5 (da)
DE (2) DE2943776A1 (da)
DK (1) DK163002C (da)
EG (1) EG14998A (da)
ES (1) ES495740A0 (da)
FI (1) FI69850C (da)
GR (1) GR71212B (da)
HU (1) HU183237B (da)
IE (1) IE52686B1 (da)
IL (1) IL61332A (da)
NO (1) NO154231C (da)
PL (1) PL125169B1 (da)
PT (1) PT71842B (da)
SU (1) SU973025A3 (da)
YU (1) YU256680A (da)
ZA (1) ZA806565B (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2943776A1 (de) * 1979-10-26 1981-05-14 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung
DE3115996A1 (de) * 1981-04-13 1982-11-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen 17(alpha)-alkyl-17(beta)-hydroxy-1(alpha)- methyl-4-androsten-3-one-.verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten
DE3322285A1 (de) * 1983-06-18 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen 1-alkyl-androsta-1,4-dien-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US4885289A (en) * 1983-12-12 1989-12-05 Breuer Miklos M Alteration of character of male beard growth
US5723502A (en) * 1985-07-18 1998-03-03 Proctor; Peter H. Topical spin trap composition and method
US5352442A (en) * 1985-07-18 1994-10-04 Proctor Peter H Topical tempo
US5714510A (en) * 1985-07-18 1998-02-03 Proctor; Peter H. Topical proxyl composition and method
US5728714A (en) * 1985-07-18 1998-03-17 Proctor; Peter H. Method for treating hair loss using tempo
US5716947A (en) * 1985-07-18 1998-02-10 Proctor; Peter H. Topical doxyl composition and method
US5472687A (en) * 1985-07-18 1995-12-05 Proctor; Peter H. Topical pyridine N-oxides
US5714482A (en) * 1985-07-18 1998-02-03 Proctor; Peter H. Topical spin labels and method
US5470876A (en) * 1985-07-18 1995-11-28 Proctor; Peter H. Topical sod for treating hair loss
US6150405A (en) * 1985-07-18 2000-11-21 Proctor; Peter H. Hair loss treatment with ascorbates
US4898694A (en) * 1987-11-25 1990-02-06 Schwartz Arthur G 17-Hydroxy-steroids
DE3824247A1 (de) * 1988-07-13 1990-01-18 Schering Ag Neue androstan-derivate
DE59207073D1 (de) * 1991-01-24 1996-10-17 Rheinische Braunkohlenw Ag Verfahren zum Behandeln von Abfällen
US5328686A (en) * 1991-10-30 1994-07-12 Douglas Shander Treatment of acne or of pseudofolliculitis barbae
ES2173874T3 (es) * 1991-11-05 2002-11-01 Gillette Co Alteracion de la velocidad y caracter del crecimiento del pelo.
US5364885A (en) * 1992-11-13 1994-11-15 Ahluwalia Gurpreet S Reduction of hair growth
US6743419B1 (en) 1992-12-22 2004-06-01 The Gillette Company Method of reducing hair growth employing sulfhydryl active compounds
US5411991A (en) * 1992-12-22 1995-05-02 Shander; Douglas Method of reducing hair growth employing sulfhydryl active compounds
US5648394A (en) * 1993-05-27 1997-07-15 Boxall; Brian Alfred Topical composition for inhibiting hair growth
US6414017B2 (en) 1993-05-28 2002-07-02 The Gillette Company Inhibition of hair growth
US6248751B1 (en) 1993-05-28 2001-06-19 Gurpreet S. Ahluwalia Inhibition of hair growth
DE69519368T2 (de) * 1994-01-06 2001-03-08 Sri International, Menlo Park Neue antiandrogenen mitteln pharmazeutische präparate und verwendungen davon
US5474763A (en) * 1994-03-11 1995-12-12 Shander; Douglas Reduction of hair growth
US5455234A (en) * 1994-03-16 1995-10-03 Ahluwalia; Gurpreet S. Inhibition of hair growth
US5468476A (en) * 1994-03-16 1995-11-21 Ahluwalia; Gurpreet S. Reduction of hair growth
US5674477A (en) * 1995-02-28 1997-10-07 Ahluwalia; Gurpreet S. Reduction of hair growth
JP4063868B2 (ja) * 1995-02-28 2008-03-19 ザ ジレット カンパニー 毛髪成長を抑制するための脈管形成抑制剤の使用
US5728736A (en) * 1995-11-29 1998-03-17 Shander; Douglas Reduction of hair growth
US5652273A (en) * 1995-11-30 1997-07-29 Henry; James Reduction of hair growth
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
US6294188B1 (en) 1998-07-09 2001-09-25 Aviana Biopharm Inc. Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women
US20070129282A1 (en) * 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
AU7736300A (en) 1999-09-30 2001-04-30 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatment of androgen receptor driven conditions
US7285109B2 (en) * 2003-02-13 2007-10-23 Boston Scientific Scimed, Inc. Device and method for collapsing an angioplasty balloon
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Crを含むタンパク質に対して特異的な受容体−結合タンパク質(rap)変異体を含む組成物およびその使用
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑-磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1382468A (fr) * 1964-01-28 1964-12-18 Spofa Vereinigte Pharma Werke Procédé de préparation des composés de 3-céto-androstane 1-méthyle-substitués, et produits conformes à ceux obtenus par le présent procédé ou procédé similaire
US3391168A (en) * 1965-08-23 1968-07-02 Searle & Co 1, 17-dimethyl-5-androstane-3beta, 17beta-diol and esters thereof
US3705180A (en) * 1971-09-02 1972-12-05 Paul D Klimstra 17-oxygenate-2-alpha-methyl-2-methylen-5 alpha-androstan-3-ones and intermediates
US4039669A (en) * 1975-08-01 1977-08-02 Sterling Drug Inc. Composition for topical application and use thereof
DE2943776A1 (de) * 1979-10-26 1981-05-14 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
PL227468A1 (da) 1981-07-10
FI69850C (fi) 1986-05-26
IL61332A0 (en) 1980-12-31
EP0027961B1 (de) 1983-01-12
FI803342L (fi) 1981-04-27
ZA806565B (en) 1981-10-28
DE3061638D1 (en) 1983-02-17
NO803172L (no) 1981-04-27
US4344941A (en) 1982-08-17
IE802202L (en) 1981-04-26
US4456600A (en) 1984-06-26
GR71212B (da) 1983-04-11
DK434380A (da) 1981-04-27
EP0027961A1 (de) 1981-05-06
DE2943776A1 (de) 1981-05-14
YU256680A (en) 1983-02-28
EG14998A (en) 1985-06-30
AU6363780A (en) 1981-04-30
DD153694A5 (de) 1982-01-27
NO154231B (no) 1986-05-05
JPS5673097A (en) 1981-06-17
DK163002B (da) 1992-01-06
PT71842B (de) 1981-07-09
ES8106539A1 (es) 1981-06-16
PL125169B1 (en) 1983-04-30
JPH0153280B2 (da) 1989-11-13
CS228507B2 (en) 1984-05-14
ES495740A0 (es) 1981-06-16
FI69850B (fi) 1985-12-31
SU973025A3 (ru) 1982-11-07
HU183237B (en) 1984-04-28
US4558041A (en) 1985-12-10
IE52686B1 (en) 1988-01-20
ATE2221T1 (de) 1983-01-15
PT71842A (de) 1980-10-01
NO154231C (no) 1986-08-13
US4892867A (en) 1990-01-09
AU532515B2 (en) 1983-10-06
DK163002C (da) 1992-06-01
CA1160216A (en) 1984-01-10

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Legal Events

Date Code Title Description
RH Patent void