ES8106539A1 - Procedimiento para la preparacion de 17x -alcohilesteroides - Google Patents

Procedimiento para la preparacion de 17x -alcohilesteroides

Info

Publication number
ES8106539A1
ES8106539A1 ES495740A ES495740A ES8106539A1 ES 8106539 A1 ES8106539 A1 ES 8106539A1 ES 495740 A ES495740 A ES 495740A ES 495740 A ES495740 A ES 495740A ES 8106539 A1 ES8106539 A1 ES 8106539A1
Authority
ES
Spain
Prior art keywords
alpha
production
preparations containing
substituted steroids
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495740A
Other languages
English (en)
Other versions
ES495740A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES495740A0 publication Critical patent/ES495740A0/es
Publication of ES8106539A1 publication Critical patent/ES8106539A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0044—Alkenyl derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE 17-X-ALCOHILESTEROIDES. SE HACE REACCIONAR UN 17-CETOESTERO DE FORMULA (I) CON UN COMPUESTO ORGANOMETALICO QUE DESPRENDE EL RADICAL R2 Y QUE SEPARA EL GRUPO PROTECTOR EN POSICION 3. OPCIONALMENTE SE ESTERIFICA O TERIFICA EL GRUPO 17-HIDROXI ANTES O DESPUES DE LOS GRUPOS PROTECTORES Y/O SE REDUCE EL GRUPO 3-CETO, Y EVENTUALMENTE, A CONTINUACION, SE ESTERIFICAN O ETIRIFICAN GRUPOS HIDROXI LIBRES EN POSICION 3 O EN POSICION 3 Y 17. SE OBTIENE EL COMPUESTO (II). *FORMULA* ACTIVIDAD ANDROGENA.
ES495740A 1979-10-26 1980-10-08 Procedimiento para la preparacion de 17x -alcohilesteroides Expired ES8106539A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792943776 DE2943776A1 (de) 1979-10-26 1979-10-26 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES495740A0 ES495740A0 (es) 1981-06-16
ES8106539A1 true ES8106539A1 (es) 1981-06-16

Family

ID=6084722

Family Applications (1)

Application Number Title Priority Date Filing Date
ES495740A Expired ES8106539A1 (es) 1979-10-26 1980-10-08 Procedimiento para la preparacion de 17x -alcohilesteroides

Country Status (23)

Country Link
US (4) US4344941A (es)
EP (1) EP0027961B1 (es)
JP (1) JPS5673097A (es)
AT (1) ATE2221T1 (es)
AU (1) AU532515B2 (es)
CA (1) CA1160216A (es)
CS (1) CS228507B2 (es)
DD (1) DD153694A5 (es)
DE (2) DE2943776A1 (es)
DK (1) DK163002C (es)
EG (1) EG14998A (es)
ES (1) ES8106539A1 (es)
FI (1) FI69850C (es)
GR (1) GR71212B (es)
HU (1) HU183237B (es)
IE (1) IE52686B1 (es)
IL (1) IL61332A (es)
NO (1) NO154231C (es)
PL (1) PL125169B1 (es)
PT (1) PT71842B (es)
SU (1) SU973025A3 (es)
YU (1) YU256680A (es)
ZA (1) ZA806565B (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2943776A1 (de) * 1979-10-26 1981-05-14 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung
DE3115996A1 (de) * 1981-04-13 1982-11-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen 17(alpha)-alkyl-17(beta)-hydroxy-1(alpha)- methyl-4-androsten-3-one-.verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten
DE3322285A1 (de) * 1983-06-18 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen 1-alkyl-androsta-1,4-dien-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US4885289A (en) * 1983-12-12 1989-12-05 Breuer Miklos M Alteration of character of male beard growth
US5728714A (en) * 1985-07-18 1998-03-17 Proctor; Peter H. Method for treating hair loss using tempo
US6150405A (en) * 1985-07-18 2000-11-21 Proctor; Peter H. Hair loss treatment with ascorbates
US5716947A (en) * 1985-07-18 1998-02-10 Proctor; Peter H. Topical doxyl composition and method
US5470876A (en) * 1985-07-18 1995-11-28 Proctor; Peter H. Topical sod for treating hair loss
US5714482A (en) * 1985-07-18 1998-02-03 Proctor; Peter H. Topical spin labels and method
US5352442A (en) * 1985-07-18 1994-10-04 Proctor Peter H Topical tempo
US5723502A (en) * 1985-07-18 1998-03-03 Proctor; Peter H. Topical spin trap composition and method
US5714510A (en) * 1985-07-18 1998-02-03 Proctor; Peter H. Topical proxyl composition and method
US5472687A (en) * 1985-07-18 1995-12-05 Proctor; Peter H. Topical pyridine N-oxides
US4898694A (en) * 1987-11-25 1990-02-06 Schwartz Arthur G 17-Hydroxy-steroids
DE3824247A1 (de) * 1988-07-13 1990-01-18 Schering Ag Neue androstan-derivate
ATE142707T1 (de) * 1991-01-24 1996-09-15 Rheinische Braunkohlenw Ag Verfahren zum behandeln von abfällen
US5328686A (en) * 1991-10-30 1994-07-12 Douglas Shander Treatment of acne or of pseudofolliculitis barbae
AU670554B2 (en) * 1991-11-05 1996-07-25 Gillette Company, The Alteration of rate and character of hair growth
US5364885A (en) * 1992-11-13 1994-11-15 Ahluwalia Gurpreet S Reduction of hair growth
US6743419B1 (en) 1992-12-22 2004-06-01 The Gillette Company Method of reducing hair growth employing sulfhydryl active compounds
US5411991A (en) * 1992-12-22 1995-05-02 Shander; Douglas Method of reducing hair growth employing sulfhydryl active compounds
US5648394A (en) * 1993-05-27 1997-07-15 Boxall; Brian Alfred Topical composition for inhibiting hair growth
US6248751B1 (en) 1993-05-28 2001-06-19 Gurpreet S. Ahluwalia Inhibition of hair growth
US6414017B2 (en) 1993-05-28 2002-07-02 The Gillette Company Inhibition of hair growth
DE69519368T2 (de) * 1994-01-06 2001-03-08 Stanford Res Inst Int Neue antiandrogenen mitteln pharmazeutische präparate und verwendungen davon
US5474763A (en) * 1994-03-11 1995-12-12 Shander; Douglas Reduction of hair growth
US5455234A (en) * 1994-03-16 1995-10-03 Ahluwalia; Gurpreet S. Inhibition of hair growth
US5468476A (en) * 1994-03-16 1995-11-21 Ahluwalia; Gurpreet S. Reduction of hair growth
US5674477A (en) * 1995-02-28 1997-10-07 Ahluwalia; Gurpreet S. Reduction of hair growth
DE69622154T2 (de) * 1995-02-28 2003-02-13 Gillette Co Verwendung von angiogenese-suppressoren zur hemmung des haarwuchses
US5728736A (en) * 1995-11-29 1998-03-17 Shander; Douglas Reduction of hair growth
US5652273A (en) * 1995-11-30 1997-07-29 Henry; James Reduction of hair growth
DE69942578D1 (de) 1998-05-22 2010-08-26 Univ R Bifunktionelle moleküle sowie darauf basierende therapien.
US6294188B1 (en) 1998-07-09 2001-09-25 Aviana Biopharm Inc. Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women
US20070129282A1 (en) * 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
DK1955700T3 (da) * 1999-09-30 2011-05-23 Harbor Biosciences Inc Terapeutisk behandling af androgenreceptor-betingede lidelser
US7285109B2 (en) * 2003-02-13 2007-10-23 Boston Scientific Scimed, Inc. Device and method for collapsing an angioplasty balloon
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1382468A (fr) * 1964-01-28 1964-12-18 Spofa Vereinigte Pharma Werke Procédé de préparation des composés de 3-céto-androstane 1-méthyle-substitués, et produits conformes à ceux obtenus par le présent procédé ou procédé similaire
US3391168A (en) * 1965-08-23 1968-07-02 Searle & Co 1, 17-dimethyl-5-androstane-3beta, 17beta-diol and esters thereof
US3705180A (en) * 1971-09-02 1972-12-05 Paul D Klimstra 17-oxygenate-2-alpha-methyl-2-methylen-5 alpha-androstan-3-ones and intermediates
US4039669A (en) * 1975-08-01 1977-08-02 Sterling Drug Inc. Composition for topical application and use thereof
DE2943776A1 (de) * 1979-10-26 1981-05-14 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI69850C (fi) 1986-05-26
EG14998A (en) 1985-06-30
IE802202L (en) 1981-04-26
US4892867A (en) 1990-01-09
DK163002B (da) 1992-01-06
FI803342L (fi) 1981-04-27
FI69850B (fi) 1985-12-31
ES495740A0 (es) 1981-06-16
HU183237B (en) 1984-04-28
PL227468A1 (es) 1981-07-10
ATE2221T1 (de) 1983-01-15
PT71842B (de) 1981-07-09
AU532515B2 (en) 1983-10-06
NO154231C (no) 1986-08-13
DE3061638D1 (en) 1983-02-17
JPH0153280B2 (es) 1989-11-13
NO803172L (no) 1981-04-27
DK163002C (da) 1992-06-01
DD153694A5 (de) 1982-01-27
US4456600A (en) 1984-06-26
NO154231B (no) 1986-05-05
GR71212B (es) 1983-04-11
AU6363780A (en) 1981-04-30
EP0027961A1 (de) 1981-05-06
CS228507B2 (en) 1984-05-14
DE2943776A1 (de) 1981-05-14
US4558041A (en) 1985-12-10
IE52686B1 (en) 1988-01-20
PL125169B1 (en) 1983-04-30
ZA806565B (en) 1981-10-28
JPS5673097A (en) 1981-06-17
EP0027961B1 (de) 1983-01-12
DK434380A (da) 1981-04-27
SU973025A3 (ru) 1982-11-07
YU256680A (en) 1983-02-28
US4344941A (en) 1982-08-17
IL61332A (en) 1985-05-31
PT71842A (de) 1980-10-01
CA1160216A (en) 1984-01-10
IL61332A0 (en) 1980-12-31

Similar Documents

Publication Publication Date Title
ES8106539A1 (es) Procedimiento para la preparacion de 17x -alcohilesteroides
AU498586B2 (en) Process for preparing a branched polycarbonate
ES300814A1 (es) Un procedimiento para la prepación de compuestos esteroides
NZ181800A (en) Preparing metal proteinate by enzymatic digestion
ES414673A1 (es) Procedimiento para preparar esteroides.
PT64885A (en) Method for preparing 17alpha-ester-21-halo pregnanes
JPS51129892A (en) Process for preparing uranium peroxide
PT68602A (en) Process for preparing plastic aquous dispersions of vinyl-polymers
HU173485B (hu) Sposob poluchenija rodenticidnykh preparatov
ES282833A1 (es) Procedimiento para la aclaración óptica de materiales orgánicos
CA1031110A (en) High yield pulping process
AU1170576A (en) Process for benz (f) 2, 5-oxazocines
HU172520B (hu) Sposob poluchenija novykh proizvodnykh ksantenovoj kisloty
ES414508A1 (es) Procedimiento de fabricacion de un compuesto de accion hi- polipemiante.
ES476452A1 (es) Un procedimiento para la produccion de una ciclohex-3-en-1- ona
ES417164A1 (es) Procedimiento para la preparacion de cardenolid-3,2-desoxi-glicosidos.
JPS51114206A (en) Increasing method for tield ratio of rice cultivation
SE7710337L (sv) Forfarande for framstellning av 9,11-halogenerade steroider
CA1016755A (en) Process for hydrometallurgical upgrading
JPS5281237A (en) Panel for plant cultivation
JPS51118676A (en) Process for producing bark compost
JPS5221168A (en) Process for producing soil conditioner by fermenting bark
ES472748A1 (es) Procedimiento para la preparacion de derivados de aminopropanol
ES465550A1 (es) Procedimiento para la obtencion de halogenopregnadienos.
JPS52658A (en) Process for producing mealy fertilizer

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401