IL54718A - 17beta-hydroxy delta4-androsten-3-ones,process for their manufacture and pharmaceutical compositions containing them - Google Patents

17beta-hydroxy delta4-androsten-3-ones,process for their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL54718A
IL54718A IL54718A IL5471878A IL54718A IL 54718 A IL54718 A IL 54718A IL 54718 A IL54718 A IL 54718A IL 5471878 A IL5471878 A IL 5471878A IL 54718 A IL54718 A IL 54718A
Authority
IL
Israel
Prior art keywords
delta4
androsten
17beta
hydroxy
ones
Prior art date
Application number
IL54718A
Other languages
English (en)
Other versions
IL54718A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19772722705 external-priority patent/DE2722705A1/de
Priority claimed from DE19772722706 external-priority patent/DE2722706A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL54718A0 publication Critical patent/IL54718A0/xx
Publication of IL54718A publication Critical patent/IL54718A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL54718A 1977-05-16 1978-05-16 17beta-hydroxy delta4-androsten-3-ones,process for their manufacture and pharmaceutical compositions containing them IL54718A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772722705 DE2722705A1 (de) 1977-05-16 1977-05-16 Androsta-4.15-dien-3-one und verfahren zu ihrer herstellung
DE19772722706 DE2722706A1 (de) 1977-05-16 1977-05-16 15.16-methylen-androsta-4.15-dien- 3-one und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IL54718A0 IL54718A0 (en) 1978-07-31
IL54718A true IL54718A (en) 1982-08-31

Family

ID=25772043

Family Applications (1)

Application Number Title Priority Date Filing Date
IL54718A IL54718A (en) 1977-05-16 1978-05-16 17beta-hydroxy delta4-androsten-3-ones,process for their manufacture and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4180570A (xx)
JP (1) JPS53141258A (xx)
AT (1) AT360676B (xx)
AU (1) AU515595B2 (xx)
CA (1) CA1105004A (xx)
CH (1) CH639105A5 (xx)
CS (1) CS200235B2 (xx)
DD (1) DD135497A5 (xx)
DK (1) DK147406C (xx)
ES (1) ES469510A1 (xx)
FR (1) FR2391224A1 (xx)
GB (1) GB1602986A (xx)
GR (1) GR71590B (xx)
HU (1) HU179345B (xx)
IE (1) IE46896B1 (xx)
IL (1) IL54718A (xx)
IT (1) IT1094627B (xx)
LU (1) LU79652A1 (xx)
NL (1) NL7805114A (xx)
SE (2) SE433356B (xx)
SU (1) SU786905A3 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2922500A1 (de) * 1979-05-31 1980-12-04 Schering Ag 6 beta .7 beta
DE3130644A1 (de) * 1981-07-29 1983-02-17 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue androstan-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten
JPS5921698A (ja) * 1982-07-22 1984-02-03 シエ−リング・アクチエンゲゼルシヤフト １７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬
DE3410880A1 (de) * 1984-03-21 1985-10-03 Schering AG, Berlin und Bergkamen, 1000 Berlin 17-substituierte estradiene und estratriene
JPS6248694A (ja) * 1985-08-28 1987-03-03 Shionogi & Co Ltd 抗アルドステロン活性ステロイド誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH609357A5 (xx) * 1973-05-25 1979-02-28 Schering Ag
DE2439082A1 (de) * 1974-08-12 1976-02-26 Schering Ag 17 alpha-hydroxy-1,3,5(10),15-oestratetraene und verfahren zu ihrer herstellung
IE44711B1 (en) * 1976-03-05 1982-03-10 Schering Ag 17 -hydroxypropyl-4-3-keto-steroids and esters thereof, and process for their manufacture

Also Published As

Publication number Publication date
DK147406B (da) 1984-07-23
US4180570A (en) 1979-12-25
CA1105004A (en) 1981-07-14
ATA348378A (de) 1980-06-15
AU3615578A (en) 1979-11-22
SE7805413L (sv) 1978-11-17
GR71590B (xx) 1983-06-17
AT360676B (de) 1981-01-26
DK213878A (da) 1978-11-17
IL54718A0 (en) 1978-07-31
AU515595B2 (en) 1981-04-09
FR2391224A1 (fr) 1978-12-15
IT1094627B (it) 1985-08-02
GB1602986A (en) 1981-11-18
CH639105A5 (de) 1983-10-31
CS200235B2 (en) 1980-08-29
FR2391224B1 (xx) 1980-06-13
DK147406C (da) 1985-02-11
LU79652A1 (de) 1978-11-06
ES469510A1 (es) 1978-12-01
IE780977L (en) 1978-11-16
SE8100829L (sv) 1981-02-05
IE46896B1 (en) 1983-10-19
HU179345B (en) 1982-10-28
NL7805114A (nl) 1978-11-20
SE433356B (sv) 1984-05-21
DD135497A5 (de) 1979-05-09
SU786905A3 (ru) 1980-12-07
JPS53141258A (en) 1978-12-08
IT7823392A0 (it) 1978-05-15

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