IL52278A - -dialkoxymethyl- -formyl(or carbaloxy)- phenyl-propionitriles, their preparation and their use as intermediates in the preparation of trimethoprim and some - Google Patents

-dialkoxymethyl- -formyl(or carbaloxy)- phenyl-propionitriles, their preparation and their use as intermediates in the preparation of trimethoprim and some

Info

Publication number
IL52278A
IL52278A IL52278A IL5227877A IL52278A IL 52278 A IL52278 A IL 52278A IL 52278 A IL52278 A IL 52278A IL 5227877 A IL5227877 A IL 5227877A IL 52278 A IL52278 A IL 52278A
Authority
IL
Israel
Prior art keywords
preparation
carbaloxy
propionitriles
dialkoxymethyl
trimethoprim
Prior art date
Application number
IL52278A
Other languages
English (en)
Other versions
IL52278A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL52278A0 publication Critical patent/IL52278A0/xx
Publication of IL52278A publication Critical patent/IL52278A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
    • A01G5/00—Floral handling
    • A01G5/04—Mountings for wreaths, or the like; Racks or holders for flowers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/27—Preparation of carboxylic acid esters from ortho-esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL52278A 1976-06-09 1977-06-08 -dialkoxymethyl- -formyl(or carbaloxy)- phenyl-propionitriles, their preparation and their use as intermediates in the preparation of trimethoprim and some IL52278A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB23756/76A GB1582245A (en) 1976-06-09 1976-06-09 Benzyl cyanoacetal derivatives and their conversion to pyrimidine derivatives

Publications (2)

Publication Number Publication Date
IL52278A0 IL52278A0 (en) 1977-08-31
IL52278A true IL52278A (en) 1981-07-31

Family

ID=10200818

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52278A IL52278A (en) 1976-06-09 1977-06-08 -dialkoxymethyl- -formyl(or carbaloxy)- phenyl-propionitriles, their preparation and their use as intermediates in the preparation of trimethoprim and some

Country Status (19)

Country Link
US (2) US4144263A (de)
JP (2) JPS5826908B2 (de)
AT (1) AT350537B (de)
AU (1) AU510298B2 (de)
BE (1) BE855505A (de)
CA (2) CA1091672A (de)
CH (1) CH632239A5 (de)
DE (1) DE2725992C2 (de)
DK (1) DK254077A (de)
FI (1) FI68612C (de)
FR (1) FR2354317A1 (de)
GB (1) GB1582245A (de)
GR (1) GR63824B (de)
HU (2) HU178138B (de)
IL (1) IL52278A (de)
NL (1) NL172541C (de)
NZ (1) NZ184330A (de)
SE (1) SE7706655L (de)
ZA (1) ZA773466B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
JPS62188328A (ja) * 1986-02-14 1987-08-17 Toshiba Seiki Kk ペレツト装着装置
JPH01152656A (ja) * 1987-12-09 1989-06-15 Sanken Electric Co Ltd リードフレームへのスクリーン印刷方法
FI895821A0 (fi) * 1988-12-07 1989-12-05 Wellcome Found Farmaceutiskt aktiva cns foereningar.
CN1930135B (zh) * 2004-03-05 2011-12-28 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3拮抗剂的二氨基嘧啶
WO2007025900A1 (en) * 2005-09-01 2007-03-08 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p3x2/3 modulators
WO2007025901A1 (en) * 2005-09-01 2007-03-08 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators
CN101296907B (zh) * 2005-09-01 2013-03-27 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2576939A (en) * 1951-12-04 -diamino-s-phenyl-e-alkyl-
US2579259A (en) * 1951-12-18 Iamino-s-
US2755298A (en) * 1956-07-17 pwiiq
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
GB1142654A (en) * 1965-10-28 1969-02-12 Wellcome Found Cyano-acetals and their use in benzylpyrimidine synthesis
US3772289A (en) * 1970-10-22 1973-11-13 Burroughs Wellcome Co Alkyl substituted benzyl pyrimidines
BE795023A (fr) * 1972-02-07 1973-08-06 Hoffmann La Roche Nouvelles benzylpyrimidines

Also Published As

Publication number Publication date
IL52278A0 (en) 1977-08-31
US4144263A (en) 1979-03-13
NL172541B (nl) 1983-04-18
BE855505A (fr) 1977-12-08
HU178138B (en) 1982-03-28
NZ184330A (en) 1979-03-28
AU510298B2 (en) 1980-06-19
JPS57136577A (en) 1982-08-23
CA1091673A (en) 1980-12-16
FR2354317B1 (de) 1980-02-01
FI771816A (de) 1977-12-10
DE2725992A1 (de) 1977-12-29
ZA773466B (en) 1978-04-26
FR2354317A1 (fr) 1978-01-06
CH632239A5 (de) 1982-09-30
NL172541C (nl) 1983-09-16
AT350537B (de) 1979-06-11
AU2591777A (en) 1978-12-14
DK254077A (da) 1977-12-10
DE2725992C2 (de) 1983-02-17
FI68612C (fi) 1985-10-10
JPS5826908B2 (ja) 1983-06-06
CA1091672A (en) 1980-12-16
GB1582245A (en) 1981-01-07
JPS6049633B2 (ja) 1985-11-02
SE7706655L (sv) 1977-12-10
HU178806B (en) 1982-06-28
FI68612B (fi) 1985-06-28
JPS52151145A (en) 1977-12-15
ATA405777A (de) 1978-11-15
NL7706284A (nl) 1977-12-13
GR63824B (en) 1979-12-19
US4216319A (en) 1980-08-05

Similar Documents

Publication Publication Date Title
ZA772866B (en) Copolyesters,preparation and use thereof
ZA765023B (en) Demetalization-desulphurization catalyst and the preparation and use thereof
IL53650A0 (en) Cyclopentan-1-amines and the preparation thereof
ZA7990B (en) New derivatives of pyridine,the preparation and use thereof
AU519620B2 (en) Azabicyclohexanes, methods of use and preparation
IL51225A0 (en) Novel 1,3,4-substituted-pyrazolines,their preparation and their use as insecticides
IL52053A (en) Prostacyclin and its biological preparation
IL52278A (en) -dialkoxymethyl- -formyl(or carbaloxy)- phenyl-propionitriles, their preparation and their use as intermediates in the preparation of trimethoprim and some
DE2960021D1 (en) Acyloxy-2-butenes, their preparation and their use for the preparation of 4-acetoxytiglinaldehyde
DE2965294D1 (en) Monoazo-compounds of the acetoacetylaminobenzimidazolone series, their preparation and use
NZ184529A (en) 5-isopropylidene-7-hydroxy-9-substituted-2,6-methano-3,4,56-tetrahydro-2h-1-benzoxocins and their preparation
IL52203A0 (en) The preparation of 3,4-dihydro-2-methyl-4-oxo-2h-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide and its use as an intermediate
JPS537665A (en) Novel ether* its preparation and its use
AU2426877A (en) Disinfectant preparation and its use
IL52586A (en) O-ethyl-s-n-propyl-o-2,2,2,-trihaloethylphosphorothiolatesand-thionothiolates,their preparation and their use as inscticides,acraricides and nematocides
IL52165A0 (en) Novel oxime-ethers their preparation and their use as fungicides
IL53038A0 (en) The preparation of certain nuclearchlorinated benzotrichlorides
GB1553321A (en) 1,2-epoxycholestene compounds their preparation and use
EG12932A (en) Novel 1-acyloxy-1-phenyl-2-azolyl-ethanes and their use as fungicides or nematicides
IL54119A0 (en) Novel 1-arylamino-2,4-dinitronaphthalenes, their preparation and their use as presticides
DE2860431D1 (en) Alpha-aminomethylene-beta-formylaminopropionitrile, process for its preparation and its use in the preparation of 2-methyl-4-amino-5-formylaminomethylpyrimidine
IL52561A0 (en) Novel diurethanes their preparation and their use as herbicides
IL68241A (en) 2,2-dihalo-6-halo-6-(1-haloisobutyl)-cyclohexanones,their preparation,and their use as intermediates in the preparation of 2,2-dimethyl-2,3-dihydro-7-hydroxy-benzofuran
IL53652A0 (en) New 1,4-oxathianes and the preparation thereof
JPS5291875A (en) Piperidinehydroxyamide and its preparation and usace thereof