IL50747A - Microbiological process for preparing 9 -hydroxy-androstenedione - Google Patents

Microbiological process for preparing 9 -hydroxy-androstenedione

Info

Publication number
IL50747A
IL50747A IL50747A IL5074776A IL50747A IL 50747 A IL50747 A IL 50747A IL 50747 A IL50747 A IL 50747A IL 5074776 A IL5074776 A IL 5074776A IL 50747 A IL50747 A IL 50747A
Authority
IL
Israel
Prior art keywords
androstenedione
hydroxy
preparing
microbiological process
microbiological
Prior art date
Application number
IL50747A
Other languages
English (en)
Other versions
IL50747A0 (en
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL50747A0 publication Critical patent/IL50747A0/xx
Publication of IL50747A publication Critical patent/IL50747A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/83—Arthrobacter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/863—Mycobacterium
    • Y10S435/866—Mycobacterium smegmatis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/867—Micromonospora
    • Y10S435/868—Micromonospora chalcea
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/867—Micromonospora
    • Y10S435/869—Micromonospora purpurea
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/872—Nocardia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/88—Serratia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL50747A 1975-10-24 1976-10-22 Microbiological process for preparing 9 -hydroxy-androstenedione IL50747A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/625,653 US4035236A (en) 1975-10-24 1975-10-24 Process for preparing 9α-hydroxyandrostenedione

Publications (2)

Publication Number Publication Date
IL50747A0 IL50747A0 (en) 1976-12-31
IL50747A true IL50747A (en) 1980-01-31

Family

ID=24507015

Family Applications (1)

Application Number Title Priority Date Filing Date
IL50747A IL50747A (en) 1975-10-24 1976-10-22 Microbiological process for preparing 9 -hydroxy-androstenedione

Country Status (12)

Country Link
US (1) US4035236A (de)
JP (3) JPS5254093A (de)
CH (1) CH624143A5 (de)
DD (1) DD127455A5 (de)
DE (1) DE2647895C3 (de)
FR (1) FR2328718A1 (de)
GB (1) GB1530730A (de)
IE (1) IE44668B1 (de)
IL (1) IL50747A (de)
MX (1) MX4502E (de)
NL (1) NL172763C (de)
PL (1) PL109912B1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293645A (en) * 1976-03-01 1981-10-06 The Upjohn Company Process for preparing androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
US4293644A (en) * 1976-10-22 1981-10-06 The Upjohn Company Process for preparing androst-4-ene-3,17-dione
US4226936A (en) * 1977-10-21 1980-10-07 The Upjohn Company Process for preparing 9α-OH BN alcohol
US4221868A (en) * 1977-10-21 1980-09-09 The Upjohn Company Process for preparing 9α-OH testosterone
US4214052A (en) * 1977-10-21 1980-07-22 The Upjohn Company Process for preparing 9α-OH BN alcohol
US4214051A (en) * 1977-10-21 1980-07-22 The Upjohn Company Process for preparing 9α-OH BN acid methyl ester
US4223092A (en) * 1977-10-21 1980-09-16 The Upjohn Company Process for preparing 9α-OH BN acid methyl ester
US4293646A (en) * 1978-08-07 1981-10-06 The Upjohn Company Composition of matter and process
JPS5585397A (en) * 1978-12-21 1980-06-27 Mitsubishi Chem Ind Ltd Microbiological preparation of 9alpha-hydroxyandrostenedione
JPS55138395A (en) * 1979-04-13 1980-10-29 Mitsubishi Chem Ind Ltd Production of 9alpha-hydroxyandrosterone compound by microorganism
ATE3991T1 (de) * 1979-10-26 1983-07-15 Schering Aktiengesellschaft Berlin Und Bergkamen Verfahren zur herstellung von 9-alpha-hydroxy-4- androsten-3,17-dion.
US4357279A (en) * 1981-05-18 1982-11-02 The Upjohn Company Preparation of corticoids from 17-keto steroids
GB2104526B (en) * 1981-07-24 1985-06-05 Upjohn Co 6-fluoro-9-hydroxyandrost-4-ene-3,17-diones and microbial preparation thereof
US4423146A (en) * 1981-08-10 1983-12-27 The Upjohn Company Composition of matter and process
US4524134A (en) * 1982-07-30 1985-06-18 The Upjohn Company Process for preparing 1,2-dehydro steroids
US4755463A (en) * 1982-05-25 1988-07-05 Wisconsin Alumni Research Foundation Process for preparing steroids
US4444884A (en) * 1982-05-25 1984-04-24 Wisconsin Alumni Research Foundation Process for preparing steroids
DE3322120A1 (de) * 1982-07-30 1984-02-02 The Upjohn Co., 49001 Kalamazoo, Mich. Verfahren zur umwandlung von 1,2-gesaettigten 3-ketosteroiden in 1,2-dehydrosteroide
US4704358A (en) * 1982-10-25 1987-11-03 The Upjohn Company Δ1 -dehydrogenation with heat or air-dried B. cyclooxidans
US4684610A (en) * 1983-03-15 1987-08-04 The Upjohn Company Process for converting 1,2-saturated steroids to 1,2-dehydro steroids
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6061165U (ja) * 1983-09-29 1985-04-27 ダイヤ精工株式会社 携帯用電動工具
JPS62124882A (ja) * 1985-11-25 1987-06-06 松下電工株式会社 電動ドライバ−
JPS62181366U (de) * 1986-05-10 1987-11-17
JPH0826062B2 (ja) * 1986-10-10 1996-03-13 ルーセル ウクラーフ ９―α―ヒドロキシステロイド及びその製法
HU196627B (en) * 1986-11-18 1988-12-28 Gyogyszerkutato Intezet Microbiological process for producing y alpha-hydroxy-4-androstene-3,17-dione
JPS63110380U (de) * 1987-01-10 1988-07-15
JP2719377B2 (ja) * 1987-12-23 1998-02-25 ルーセル ウクラーフ ９α―ヒドロキシ―１７―ケトステロイドの微生物学的製法
US5298398A (en) * 1987-12-23 1994-03-29 Gist-Brocades Nv Preparation of 9-α-hydroxy-17-keto steroids using Mycobacterium species CBS 482.86
US5215894A (en) * 1992-02-25 1993-06-01 Merck & Co., Inc. Biological process for producing 17β-N-monosubstituted carbamoyl-11-oxo-4-aza-5-α-androst-3-one testosterone-5-α reductase inhibitors
HU227238B1 (en) * 2006-09-15 2010-12-28 Richter Gedeon Nyrt Process for obtaining selectively monohydroxylated 3,17-diketo steroid compounds, purification and separation thereof
HU227304B1 (en) 2007-07-04 2011-02-28 Richter Gedeon Nyrt Process for producing 9alpha-hydroxy-steroids
CN103343155B (zh) * 2013-06-26 2015-04-01 山西祖源工贸有限公司 一种制备9a-羟基雄烯二酮的方法
CN105886418B (zh) * 2014-12-01 2020-04-17 浙江神洲药业有限公司 偶发分枝杆菌在发酵生产表博醇中的应用
CN105734106A (zh) * 2014-12-10 2016-07-06 天津金耀集团有限公司 一种促进植物甾醇转化为9α-羟基雄烯二酮的方法
CN105838633A (zh) * 2015-01-13 2016-08-10 上海市农药研究所有限公司 一种偶发分枝杆菌及其应用
CN107099485B (zh) * 2017-06-26 2019-10-08 中国科学院广州地球化学研究所 一株去氢孕酮降解菌及其应用
CN109652338B (zh) * 2019-01-24 2021-04-09 天津科技大学 高产9α-OH-AD的偶发分枝杆菌及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione

Also Published As

Publication number Publication date
NL172763C (nl) 1983-10-17
IL50747A0 (en) 1976-12-31
JPS55148099A (en) 1980-11-18
US4035236A (en) 1977-07-12
CH624143A5 (de) 1981-07-15
MX4502E (es) 1982-05-24
DE2647895A1 (de) 1977-05-05
PL109912B1 (en) 1980-06-30
JPS6029470B2 (ja) 1985-07-10
DD127455A5 (de) 1977-09-21
NL172763B (nl) 1983-05-16
JPS5254093A (en) 1977-05-02
IE44668B1 (en) 1982-02-24
NL7611711A (nl) 1977-04-26
FR2328718A1 (fr) 1977-05-20
GB1530730A (en) 1978-11-01
JPS55148085A (en) 1980-11-18
JPS5642919B2 (de) 1981-10-07
DE2647895B2 (de) 1980-05-22
IE44668L (en) 1977-04-24
FR2328718B1 (de) 1980-03-14
DE2647895C3 (de) 1981-04-02

Similar Documents

Publication Publication Date Title
IL50747A (en) Microbiological process for preparing 9 -hydroxy-androstenedione
HU174396B (hu) Sposob poluchenija 17-al'fa-gidroksi-kortikosteroidov
JPS527943A (en) Process for preparing same
JPS5273833A (en) Process for preparing orthoo hydroxyarylaldehyde
CS191310B2 (en) Process for preparing 11-deoxy-16-aryloxy-omega-tetranorprostaglandines
GB1548032A (en) Process for preparing amono-acid admides
HU175022B (hu) Sposob poluchenija 11-deoksi-acetilen-aril-prostaglandinov
CS185596B2 (en) Process for preparing new propargyl-2-phenylamino-2-imidazolines
JPS5239608A (en) Process for preparing perfluoroalkyliodide teromer
YU208176A (en) Process for preparing n-tetrahydrofurfuryl-nor-oximorphones
HU172964B (hu) Sposob poluchenija n-aril-n-/1-l-4-piperidinil/-aril-acetamidov
JPS52233A (en) Process for preparing paraaalkylphenol
HU174650B (hu) Sposob poluchenija l-piroglutamil-l-prolinamida
JPS5273803A (en) Process for preparing halogenoalkene
JPS51115453A (en) Process for preparing 22naphtylaminee 11sulphonate
GB1542488A (en) Process for preparing alpha-amino-gamma-methylmercaptobutyronitrile
HU174888B (hu) Sposob poluchenija 1-naftil-n-metil-karbamata
JPS51125467A (en) Process for preparing graftcopolymer
HU175729B (hu) Sposob poluchenija ftoroprostaglandinov
HU174777B (hu) Sposob poluchenija 2-acilamino-oksazolov
JPS5210202A (en) Process for preparing c2hydrocarbon
GB1543929A (en) Process for preparing dihalovinylcyclopropane-carboxylates
HU174667B (hu) Sposob poluchenija omega-amino-alkankarbonil-aril-amidov
HU174633B (hu) Sposob poluchenija glikolal'degida
EG12462A (en) Process for preparing imidazolobenzodiazepines