IL48453A - Substituted 6-oxa-1-azatricyclo-(6.2.2.0 )dodecan-5-ones and 1,4-ethano-5-oxo octa (or decahydro)quinoline,their preparation and pharmaceutical compositions containing them - Google Patents

Substituted 6-oxa-1-azatricyclo-(6.2.2.0 )dodecan-5-ones and 1,4-ethano-5-oxo octa (or decahydro)quinoline,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL48453A
IL48453A IL48453A IL4845375A IL48453A IL 48453 A IL48453 A IL 48453A IL 48453 A IL48453 A IL 48453A IL 4845375 A IL4845375 A IL 4845375A IL 48453 A IL48453 A IL 48453A
Authority
IL
Israel
Prior art keywords
designates
substituted
pharmaceutical compositions
compositions containing
dodecan
Prior art date
Application number
IL48453A
Other languages
English (en)
Other versions
IL48453A0 (en
Inventor
A Fisher
Cohen Sasson
Original Assignee
Purdue Frederick Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Frederick Co filed Critical Purdue Frederick Co
Priority to IL48453A priority Critical patent/IL48453A/xx
Publication of IL48453A0 publication Critical patent/IL48453A0/xx
Priority to US05/655,650 priority patent/US4083985A/en
Priority to AR265267A priority patent/AR213184A1/es
Priority to FI763152A priority patent/FI60013C/fi
Priority to DE19762650876 priority patent/DE2650876A1/de
Priority to ZA766663A priority patent/ZA766663B/xx
Priority to NZ182556A priority patent/NZ182556A/xx
Priority to NL7612427A priority patent/NL7612427A/xx
Priority to CH1417776A priority patent/CH635102A5/de
Priority to BE172272A priority patent/BE848227A/xx
Priority to FR7634034A priority patent/FR2331339A1/fr
Priority to DK507376A priority patent/DK507376A/da
Priority to ES453162A priority patent/ES453162A1/es
Priority to CA265,344A priority patent/CA1078385A/en
Priority to NO763820A priority patent/NO144927C/no
Priority to GB46748/76A priority patent/GB1571511A/en
Priority to IN2028/CAL/1976A priority patent/IN145202B/en
Priority to SE7612527A priority patent/SE426699B/xx
Priority to MX765119U priority patent/MX4767E/es
Priority to AT839476A priority patent/AT355035B/de
Priority to AU19552/76A priority patent/AU511347B2/en
Priority to JP51136167A priority patent/JPS6045198B2/ja
Priority to US05/852,402 priority patent/US4183938A/en
Priority to IN730/CAL/78A priority patent/IN147756B/en
Priority to US05/953,514 priority patent/US4226996A/en
Priority to AT926178A priority patent/AT356665B/de
Priority to US06/058,968 priority patent/US4309544A/en
Priority to SE8003351A priority patent/SE435929B/sv
Publication of IL48453A publication Critical patent/IL48453A/xx
Priority to CH267282A priority patent/CH640234A5/de
Priority to JP59166668A priority patent/JPS6043348B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL48453A 1975-11-11 1975-11-11 Substituted 6-oxa-1-azatricyclo-(6.2.2.0 )dodecan-5-ones and 1,4-ethano-5-oxo octa (or decahydro)quinoline,their preparation and pharmaceutical compositions containing them IL48453A (en)

Priority Applications (30)

Application Number Priority Date Filing Date Title
IL48453A IL48453A (en) 1975-11-11 1975-11-11 Substituted 6-oxa-1-azatricyclo-(6.2.2.0 )dodecan-5-ones and 1,4-ethano-5-oxo octa (or decahydro)quinoline,their preparation and pharmaceutical compositions containing them
US05/655,650 US4083985A (en) 1975-11-11 1976-02-06 6-Oxa-1-aza tricyclo dodecan-5-ones as psychomotor stimulators
AR265267A AR213184A1 (es) 1975-11-11 1976-10-28 Procedimiento para preparar derivados de 1,4-etan-6-oxo-perhidroquinoleina y sus sales
FI763152A FI60013C (fi) 1975-11-11 1976-11-03 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,4-etano-7-alkyl- och 1,4-etano-7-arylperhydrokinolin-6-oner
DE19762650876 DE2650876A1 (de) 1975-11-11 1976-11-06 Neue quinuklidine
ZA766663A ZA766663B (en) 1975-11-11 1976-11-08 Novel heterocyclic compounds and pharmaceutical composition containing them
NZ182556A NZ182556A (en) 1975-11-11 1976-11-08 Tricylick azacyloalkanones
NL7612427A NL7612427A (nl) 1975-11-11 1976-11-09 Werkwijze voor de bereiding van nieuwe chinoline- derivaten.
SE7612527A SE426699B (sv) 1975-11-11 1976-11-10 Analogiforfarande for framstellning av kondenserade kinuklidinforeningar med terapeutisk verkan
NO763820A NO144927C (no) 1975-11-11 1976-11-10 Analogifremgangsmaate ved fremstilling av terapeutisk aktive kinuclidinderivater
BE172272A BE848227A (fr) 1975-11-11 1976-11-10 Nouveaux composes heterocycliques et compositions pharmaceutiques les contenant,
FR7634034A FR2331339A1 (fr) 1975-11-11 1976-11-10 Nouveaux composes heterocycliques et composition pharmaceutique les contenant
DK507376A DK507376A (da) 1975-11-11 1976-11-10 Heterocycliske forbindelser og fysiologisk acceptable salte deraf samt fremgangsmade til fremstilling deraf
ES453162A ES453162A1 (es) 1975-11-11 1976-11-10 Un procedimiento para la obtencion de compuestos heteroci- clicos.
CA265,344A CA1078385A (en) 1975-11-11 1976-11-10 1,4-ethano-6-oxo-octahydro-quinoline and 6-oxa-1-aza tricyclododecan-5-one compounds
CH1417776A CH635102A5 (de) 1975-11-11 1976-11-10 Verfahren zur herstellung neuer heterocyclischer verbindungen.
GB46748/76A GB1571511A (en) 1975-11-11 1976-11-10 Fused quinuclidine derivatives and pharmaceutical compositions containing them
IN2028/CAL/1976A IN145202B (xx) 1975-11-11 1976-11-10
JP51136167A JPS6045198B2 (ja) 1975-11-11 1976-11-11 縮合環キヌクリジン−バレロラクトン系化合物及びその製法
AT839476A AT355035B (de) 1975-11-11 1976-11-11 Verfahren zum herstellen neuer chinuclidin- derivate, ihren stereoisomeren, optischen isomeren und salzen
MX765119U MX4767E (es) 1975-11-11 1976-11-11 Procedimiento para la preparacion de derivados del 1,8-etano-5-oxo octa y decahidroquinolinas
AU19552/76A AU511347B2 (en) 1975-11-11 1976-11-11 Quinuclidine derivatives with pharmaceutical properties
US05/852,402 US4183938A (en) 1975-11-11 1977-11-17 1,8-Ethano-5-oxo-octa- and -decahydroquinolines and mydriatic compositions thereof
IN730/CAL/78A IN147756B (xx) 1975-11-11 1978-07-01
US05/953,514 US4226996A (en) 1975-11-11 1978-10-23 Novel heterocyclic compounds and pharmaceutical composition containing them
AT926178A AT356665B (de) 1975-11-11 1978-12-22 Verfahren zum herstellen neuer chinuclidin- derivate, ihren stereoisomeren, optischen isomeren und salzen
US06/058,968 US4309544A (en) 1975-11-11 1979-07-20 Preparation of 6-oxa-1-azatricyclo(6.2.2.02,7)dodecane-5-ones
SE8003351A SE435929B (sv) 1975-11-11 1980-05-05 Forfarande for framstellning av 6-oxa-1-azatricyklo (4.2.2.0?722,7)-dodekan-5-oner med terapeutisk verkan
CH267282A CH640234A5 (de) 1975-11-11 1982-04-30 Verfahren zur herstellung neuer heterocyclischer verbindungen.
JP59166668A JPS6043348B2 (ja) 1975-11-11 1984-08-10 新規化合物またはその生理的に許容可能な塩及びこれらの製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL48453A IL48453A (en) 1975-11-11 1975-11-11 Substituted 6-oxa-1-azatricyclo-(6.2.2.0 )dodecan-5-ones and 1,4-ethano-5-oxo octa (or decahydro)quinoline,their preparation and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IL48453A0 IL48453A0 (en) 1976-01-30
IL48453A true IL48453A (en) 1980-06-30

Family

ID=11048546

Family Applications (1)

Application Number Title Priority Date Filing Date
IL48453A IL48453A (en) 1975-11-11 1975-11-11 Substituted 6-oxa-1-azatricyclo-(6.2.2.0 )dodecan-5-ones and 1,4-ethano-5-oxo octa (or decahydro)quinoline,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US4083985A (xx)
JP (2) JPS6045198B2 (xx)
AR (1) AR213184A1 (xx)
AT (1) AT355035B (xx)
AU (1) AU511347B2 (xx)
BE (1) BE848227A (xx)
CA (1) CA1078385A (xx)
CH (2) CH635102A5 (xx)
DE (1) DE2650876A1 (xx)
DK (1) DK507376A (xx)
ES (1) ES453162A1 (xx)
FI (1) FI60013C (xx)
FR (1) FR2331339A1 (xx)
GB (1) GB1571511A (xx)
IL (1) IL48453A (xx)
IN (1) IN145202B (xx)
MX (1) MX4767E (xx)
NL (1) NL7612427A (xx)
NO (1) NO144927C (xx)
NZ (1) NZ182556A (xx)
SE (1) SE435929B (xx)
ZA (1) ZA766663B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4183938A (en) * 1975-11-11 1980-01-15 The Purdue Frederick Company 1,8-Ethano-5-oxo-octa- and -decahydroquinolines and mydriatic compositions thereof
US4855290A (en) 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
US4876260A (en) * 1987-10-28 1989-10-24 State Of Israel, Israel Institute Of Biological Research Oxathiolanes
JPH0523864Y2 (xx) * 1989-09-05 1993-06-17
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
US5852029A (en) * 1990-04-10 1998-12-22 Israel Institute For Biological Research Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity
JPH0518551U (ja) * 1991-08-28 1993-03-09 亀吉 立花 ぶら下がり健康器
US5521193A (en) * 1992-06-24 1996-05-28 G. D. Searle & Co. Benzimidazole compounds
US5280028A (en) * 1992-06-24 1994-01-18 G. D. Searle & Co. Benzimidazole compounds
US5534521A (en) * 1993-06-23 1996-07-09 G. D. Searle & Co. Benzimidazole compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857837A (en) * 1968-07-02 1974-12-31 Hoffmann La Roche Processes and intermediated for quinine, quinidine, isomers and derivatives thereof

Also Published As

Publication number Publication date
FR2331339B1 (xx) 1980-04-04
ES453162A1 (es) 1977-11-01
ZA766663B (en) 1977-10-26
AU1955276A (en) 1978-05-18
CH640234A5 (de) 1983-12-30
FR2331339A1 (fr) 1977-06-10
IL48453A0 (en) 1976-01-30
NZ182556A (en) 1979-10-25
SE435929B (sv) 1984-10-29
DK507376A (da) 1977-05-12
ATA839476A (de) 1979-07-15
JPS6043348B2 (ja) 1985-09-27
CH635102A5 (de) 1983-03-15
JPS5283396A (en) 1977-07-12
NO144927C (no) 1981-12-09
BE848227A (fr) 1977-03-01
NO144927B (no) 1981-08-31
GB1571511A (en) 1980-07-16
AU511347B2 (en) 1980-08-14
CA1078385A (en) 1980-05-27
FI60013C (fi) 1981-11-10
JPS60120876A (ja) 1985-06-28
US4083985A (en) 1978-04-11
MX4767E (es) 1982-09-08
NL7612427A (nl) 1977-05-13
AT355035B (de) 1980-02-11
NO763820L (xx) 1977-05-12
FI60013B (fi) 1981-07-31
JPS6045198B2 (ja) 1985-10-08
FI763152A (xx) 1977-05-12
AR213184A1 (es) 1978-12-29
DE2650876A1 (de) 1977-05-18
SE8003351L (sv) 1980-05-05
IN145202B (xx) 1978-09-09

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