IL47921A - Alpha-(3,4,5-triethoxybenzyl)-acrylonitrile and-propionitrile derivatives and their preparation - Google Patents
Alpha-(3,4,5-triethoxybenzyl)-acrylonitrile and-propionitrile derivatives and their preparationInfo
- Publication number
- IL47921A IL47921A IL47921A IL4792172A IL47921A IL 47921 A IL47921 A IL 47921A IL 47921 A IL47921 A IL 47921A IL 4792172 A IL4792172 A IL 4792172A IL 47921 A IL47921 A IL 47921A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- preparation
- anilino
- group
- compounds
- Prior art date
Links
- WSMHIJKVOOKVKZ-UHFFFAOYSA-N 2-[(3,4,5-triethoxyphenyl)methyl]prop-2-enenitrile Chemical compound C(C)OC=1C=C(CC(C#N)=C)C=C(C1OCC)OCC WSMHIJKVOOKVKZ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 7
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 3
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- FENJKTQEFUPECW-UHFFFAOYSA-N 3-anilinopropanenitrile Chemical compound N#CCCNC1=CC=CC=C1 FENJKTQEFUPECW-UHFFFAOYSA-N 0.000 claims 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- -1 alkoxide anion Chemical class 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 claims 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical class CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 claims 1
- HHVIBTZHLRERCL-UHFFFAOYSA-N sulfonyldimethane Chemical compound CS(C)(=O)=O HHVIBTZHLRERCL-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB963971A GB1407971A (en) | 1971-04-16 | 1971-04-16 | 2,4-diamino -4-3,4,5-triethoxybenzyl pyrimidine and methods of preparation therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL47921A true IL47921A (en) | 1976-10-31 |
Family
ID=9875880
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL47921A IL47921A (en) | 1971-04-16 | 1972-04-14 | Alpha-(3,4,5-triethoxybenzyl)-acrylonitrile and-propionitrile derivatives and their preparation |
| IL39218A IL39218A (en) | 1971-04-16 | 1972-04-14 | 2,4-diamino-5-(3,4,5-triethoxybenzyl) pyrimidine its preparation and pharmaceutical compositions containing it |
| IL47921A IL47921A0 (en) | 1971-04-16 | 1975-08-14 | New alpha-(3,4,5-triethoxybenzyl)-acrylonitrile and-propionitrile derivatives and their preparation |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL39218A IL39218A (en) | 1971-04-16 | 1972-04-14 | 2,4-diamino-5-(3,4,5-triethoxybenzyl) pyrimidine its preparation and pharmaceutical compositions containing it |
| IL47921A IL47921A0 (en) | 1971-04-16 | 1975-08-14 | New alpha-(3,4,5-triethoxybenzyl)-acrylonitrile and-propionitrile derivatives and their preparation |
Country Status (13)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA738760B (en) * | 1972-12-21 | 1974-08-28 | Hoffmann La Roche | Process for the manufacture of benzyl pyrimidines |
| GB1469521A (en) * | 1973-01-05 | 1977-04-06 | Wellcome Found | Antimicrobial preparations |
| FR2502152A1 (fr) * | 1981-03-20 | 1982-09-24 | Panmedica Laboratoires | Nouveaux derives solubles n2 substitues de la diamino-2,4-benzyl-5-pyrimidines, leur procede de preparation et medicaments les contenant |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1090394A (fr) * | 1953-03-11 | 1955-03-30 | Wellcome Found | Dérivés de pyrimidine et leur fabrication |
| FR1459417A (fr) * | 1964-11-12 | 1966-04-29 | Hoffmann La Roche | Procédé pour la préparation de dérivés de pyrimidine |
| FR1518635A (fr) * | 1965-07-08 | 1968-03-29 | Wellcome Found | Procédé de préparation de dérivés de la pyrimidine |
| GB1261455A (en) * | 1969-03-06 | 1972-01-26 | Burroughs Wellcome Co | Improvements in or relating to substituted acrylonitriles |
-
1971
- 1971-04-16 GB GB963971A patent/GB1407971A/en not_active Expired
-
1972
- 1972-04-14 IL IL47921A patent/IL47921A/en unknown
- 1972-04-14 CS CS7200002539A patent/CS181221B2/cs unknown
- 1972-04-14 CH CH554572A patent/CH565160A5/xx not_active IP Right Cessation
- 1972-04-14 NL NL7205043A patent/NL7205043A/xx not_active Application Discontinuation
- 1972-04-14 AU AU41174/72A patent/AU468447B2/en not_active Expired
- 1972-04-14 SE SE7204847A patent/SE391180B/xx unknown
- 1972-04-14 DK DK184372AA patent/DK131466B/da unknown
- 1972-04-14 IL IL39218A patent/IL39218A/en unknown
- 1972-04-14 DE DE19722218220 patent/DE2218220A1/de active Pending
- 1972-04-14 BE BE782153A patent/BE782153A/xx unknown
- 1972-04-14 JP JP3763772A patent/JPS5320511B1/ja active Pending
- 1972-04-14 FR FR7213215A patent/FR2133752B1/fr not_active Expired
- 1972-04-14 CA CA139,774A patent/CA967964A/en not_active Expired
-
1975
- 1975-08-14 IL IL47921A patent/IL47921A0/xx unknown
-
1977
- 1977-12-22 JP JP15503677A patent/JPS5430189A/ja active Granted
- 1977-12-22 JP JP15503777A patent/JPS53111083A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL39218A0 (en) | 1972-06-28 |
| JPS5422994B2 (enrdf_load_stackoverflow) | 1979-08-10 |
| AU468447B2 (en) | 1976-01-15 |
| FR2133752B1 (enrdf_load_stackoverflow) | 1975-04-25 |
| BE782153A (fr) | 1972-10-16 |
| GB1407971A (en) | 1975-10-01 |
| JPS5430189A (en) | 1979-03-06 |
| NL7205043A (enrdf_load_stackoverflow) | 1972-10-18 |
| DE2218220A1 (de) | 1972-11-02 |
| SE391180B (sv) | 1977-02-07 |
| DK131466C (enrdf_load_stackoverflow) | 1975-12-08 |
| CS181221B2 (en) | 1978-03-31 |
| FR2133752A1 (enrdf_load_stackoverflow) | 1972-12-01 |
| JPS5320511B1 (enrdf_load_stackoverflow) | 1978-06-27 |
| JPS53111083A (en) | 1978-09-28 |
| IL47921A0 (en) | 1975-11-25 |
| CA967964A (en) | 1975-05-20 |
| CH565160A5 (enrdf_load_stackoverflow) | 1975-08-15 |
| IL39218A (en) | 1976-10-31 |
| AU4117472A (en) | 1973-10-18 |
| DK131466B (da) | 1975-07-21 |
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