IL42126A - 7-(alpha-amino-p-hydroxyphenylacetamido)-3-(1,2,3-triazolyl thiomethyl)3-cephem-4-carboxylic acid derivatives - Google Patents

7-(alpha-amino-p-hydroxyphenylacetamido)-3-(1,2,3-triazolyl thiomethyl)3-cephem-4-carboxylic acid derivatives

Info

Publication number
IL42126A
IL42126A IL42126A IL4212673A IL42126A IL 42126 A IL42126 A IL 42126A IL 42126 A IL42126 A IL 42126A IL 4212673 A IL4212673 A IL 4212673A IL 42126 A IL42126 A IL 42126A
Authority
IL
Israel
Prior art keywords
hydroxyphenylacetamido
cephem
thiomethyl
triazolyl
alpha
Prior art date
Application number
IL42126A
Other languages
English (en)
Other versions
IL42126A0 (en
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US262903A external-priority patent/US3867380A/en
Priority claimed from US00289499A external-priority patent/US3855213A/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL42126A0 publication Critical patent/IL42126A0/xx
Publication of IL42126A publication Critical patent/IL42126A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL42126A 1972-06-14 1973-04-27 7-(alpha-amino-p-hydroxyphenylacetamido)-3-(1,2,3-triazolyl thiomethyl)3-cephem-4-carboxylic acid derivatives IL42126A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US262903A US3867380A (en) 1971-02-18 1972-06-14 3-Heterocyclic thiomethylcephalosporins
US00289499A US3855213A (en) 1971-02-18 1972-09-15 3-heterocyclic thiomethyl-cephalosporins

Publications (2)

Publication Number Publication Date
IL42126A0 IL42126A0 (en) 1973-06-29
IL42126A true IL42126A (en) 1975-12-31

Family

ID=26949532

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42126A IL42126A (en) 1972-06-14 1973-04-27 7-(alpha-amino-p-hydroxyphenylacetamido)-3-(1,2,3-triazolyl thiomethyl)3-cephem-4-carboxylic acid derivatives

Country Status (20)

Country Link
JP (2) JPS5518716B2 (de)
AR (1) AR197237A1 (de)
AT (1) AT324560B (de)
AU (1) AU464107B2 (de)
CA (2) CA1076560A (de)
CH (2) CH586709A5 (de)
DD (1) DD105238A5 (de)
DE (1) DE2316867C2 (de)
DK (1) DK142913B (de)
ES (2) ES412207A1 (de)
FI (1) FI56843C (de)
FR (2) FR2187298B1 (de)
GB (2) GB1363833A (de)
HU (1) HU168689B (de)
IE (2) IE37409B1 (de)
IL (1) IL42126A (de)
NL (2) NL7302817A (de)
PH (1) PH9941A (de)
PL (1) PL91074B1 (de)
SE (2) SE416472B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR780000197B1 (en) * 1972-12-26 1978-05-26 Bristol Myers Co Method for preparing antibacterial agent
FR2215942B1 (de) * 1973-01-31 1978-12-22 Bristol Myers Co
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
CA1074784A (en) * 1974-09-06 1980-04-01 Sumitomo Chemical Company N-ACYLAMINO-.alpha.-ARYLACETAMIDO CEPHALOSPORINS
JPS5346995A (en) * 1976-10-12 1978-04-27 Sangyo Kagaku Kenkyu Kyokai Antibacterial agents
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
JPS6010226U (ja) * 1983-06-30 1985-01-24 松下電工株式会社 昇降装置
JPS6182606A (ja) * 1984-09-29 1986-04-26 東芝ライテック株式会社 昇降装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA698494B (en) * 1969-02-26 1971-07-28 Lilly Co Eli Sulfur-containing cephalosporing antibiotics
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
DK142913C (de) 1981-09-28
IE37499B1 (en) 1977-08-03
FR2187298B1 (de) 1976-12-03
FR2187299A1 (de) 1974-01-18
JPS4954393A (de) 1974-05-27
FI56843B (fi) 1979-12-31
DE2316866B2 (de) 1976-10-07
IL42126A0 (en) 1973-06-29
FR2187299B1 (de) 1976-12-03
DE2316867C2 (de) 1982-05-19
NL7302817A (de) 1973-12-18
SE404190B (sv) 1978-09-25
AT324560B (de) 1975-09-10
AU464107B2 (en) 1975-08-14
JPS5518716B2 (de) 1980-05-21
PL91074B1 (en) 1977-02-28
HU168689B (de) 1976-06-28
IE37409B1 (en) 1977-07-20
DE2316867A1 (de) 1974-01-03
DD105238A5 (de) 1974-04-12
CA1076560A (en) 1980-04-29
ES412207A1 (es) 1976-01-01
IE37499L (en) 1973-12-14
CA999293A (en) 1976-11-02
NL7305206A (de) 1973-12-18
JPS5953274B2 (ja) 1984-12-24
PH9941A (en) 1976-06-14
AU5234573A (en) 1974-08-22
AR197237A1 (es) 1974-03-22
FI56843C (fi) 1980-04-10
GB1358027A (en) 1974-06-26
DE2316866A1 (de) 1974-01-03
JPS4931689A (de) 1974-03-22
CH589093A5 (de) 1977-06-30
CH586709A5 (de) 1977-04-15
ES413501A1 (es) 1976-07-16
DK142913B (da) 1981-02-23
IE37409L (en) 1973-12-14
GB1363833A (en) 1974-08-21
SE416472B (sv) 1981-01-05
FR2187298A1 (de) 1974-01-18

Similar Documents

Publication Publication Date Title
YU39521B (en) Process for the manufacture of new 1,2,4-triazole derivatives
HK3277A (en) Prostanoic acid derivatives
IL43348A0 (en) 1-oxo-2,2-disubstituted-5-indanyloxy-(or thio) alkanoic acids
ZA737357B (en) Prostanoic acid derivatives
GB1407348A (en) Cephalosporanic acid derivatives
CA986923A (en) Process for preparing 7-(o-aminomethylphenylacetamido)-3-((heterocyclic thio)-methyl) ceph-3-em-4-carboxylic acids
CA1004220A (en) 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacetamido) desacetoxycephalosporanic acid dihydrate
IL42126A (en) 7-(alpha-amino-p-hydroxyphenylacetamido)-3-(1,2,3-triazolyl thiomethyl)3-cephem-4-carboxylic acid derivatives
CA1014950A (en) 7-(0-amino-methylphenylacetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
CA1013344A (en) 7-(0-aminomethylphenyl-acetamido)-3-(tetrazolo(4,5-b)-pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
AU5428373A (en) 6-/& (guanylureidoalkanylamino) aracylamino/penicillanic acids
IE39343L (en) 2-loweralkyl -2 or 3-cephem-4-carboxylic acid derivatives
IL45692A (en) 7-(cyanomethylaryl)acetamido cephalosporin derivatives
AU471195B2 (en) Herbicidal thioprorionic acid derivatives
JPS57176968A (en) (1-oxo-2,3-hydrocarbylene-5-indanyloxy(or thio))alkanoic acid
CA983020A (en) 7-(D-(.alpha.-AMINO-.alpha.-PHENYLACETAMIDO))-3-(5-METHYL-1,3,4-OXADIAZOL-2-YLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID AND SALTS THEREOF
IL45936A0 (en) 7-(alpha-(3-guanyl-1-ureido)phenyl-acetamido)-3-cephem-4-carboxylic acid derivatives
CA999292A (en) 7-(D-(.alpha.-AMINO-.alpha.-PHENYL-,THIENYL-ACETAMIDO))-3-5-(HETEROCYCLIC)CARBONYL) THIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACIDS
JPS5767556A (en) Manufacture of 9-desoxy-prosta-5,9(10),13- trienic acid derivative
CA835981A (en) 7-(sydnone-2-acetamido)-cephalosporanic acid
CA903767A (en) Prostanoic acid derivatives
AU481170B2 (en) Prostanoic acid derivatives
AU482145B2 (en) Prostanoic acid derivatives
YU39712B (en) Process for obtaining cephalosporanic acid derivatives
CA1014951A (en) 7-(0-amino-methylphenylacetamido)-3-(3-hydroxypyridazin -6-ylthiomethyl)-3-cephem-4-carboxylic acid and intermediates therefor