PH16419A - 7-(d-alpha-amino-alpha-(3'-methyl-4'-hydroxyphenyl)-acetamido)-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid,pharmaceutically acceptable esters and salts thereof - Google Patents

7-(d-alpha-amino-alpha-(3'-methyl-4'-hydroxyphenyl)-acetamido)-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid,pharmaceutically acceptable esters and salts thereof

Info

Publication number
PH16419A
PH16419A PH15486A PH15486A PH16419A PH 16419 A PH16419 A PH 16419A PH 15486 A PH15486 A PH 15486A PH 15486 A PH15486 A PH 15486A PH 16419 A PH16419 A PH 16419A
Authority
PH
Philippines
Prior art keywords
alpha
ylthiomethyl
cephem
acetamido
triazol
Prior art date
Application number
PH15486A
Inventor
Richard Baker Stephen
Truman Holdrege Charles
Cheney Cannon
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of PH16419A publication Critical patent/PH16419A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH15486A 1973-01-31 1974-01-31 7-(d-alpha-amino-alpha-(3'-methyl-4'-hydroxyphenyl)-acetamido)-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid,pharmaceutically acceptable esters and salts thereof PH16419A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32823473A 1973-01-31 1973-01-31
US36169673A 1973-05-18 1973-05-18

Publications (1)

Publication Number Publication Date
PH16419A true PH16419A (en) 1983-09-29

Family

ID=26986279

Family Applications (2)

Application Number Title Priority Date Filing Date
PH15486A PH16419A (en) 1973-01-31 1974-01-31 7-(d-alpha-amino-alpha-(3'-methyl-4'-hydroxyphenyl)-acetamido)-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid,pharmaceutically acceptable esters and salts thereof
PH20034A PH14842A (en) 1973-01-31 1977-07-26 Chemical process

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH20034A PH14842A (en) 1973-01-31 1977-07-26 Chemical process

Country Status (7)

Country Link
JP (1) JPS5953275B2 (en)
CA (1) CA1035353A (en)
DE (1) DE2404592C2 (en)
FR (2) FR2215942B1 (en)
GB (1) GB1439419A (en)
NL (1) NL7401361A (en)
PH (2) PH16419A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL49183A0 (en) * 1975-03-27 1976-05-31 Pfizer Novel cephalosporin derivatives,their preparation and pharmaceutical compositions containing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6915169D0 (en) * 1969-04-21 1973-02-20 Bristol Myers Co CHEMICAL PROCESS
NL7112483A (en) * 1970-09-14 1972-03-16
IL38099A (en) * 1970-12-17 1976-01-30 Smith Kline French Lab 3-heterocyclyl thiomethylcephalosporins
AU463529B2 (en) * 1971-01-18 1975-07-31 Bristol-Myers Company Cephalosporin derivatives and process fob the preparation thereof
US3757014A (en) * 1971-05-07 1973-09-04 Bristol Myers Co Ts 1,3,4 - oxadiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid and sal7-(d-(alpha-amino-alpha-pheyle-acetamido)) - 3-(s-(5-hydroxymethyl -
CA1076560A (en) * 1972-06-14 1980-04-29 Smith Kline And French Canada Ltd. 3-heterocyclic thiomethylcephalosporins
CA999574A (en) * 1972-06-14 1976-11-09 Smith Kline And French Canada Ltd. 7-hydroxyhalophenylacetamido-3-h heterocyclicthiomethyl cephalosporins

Also Published As

Publication number Publication date
FR2215942B1 (en) 1978-12-22
DE2404592A1 (en) 1974-08-01
DE2404592C2 (en) 1984-01-19
GB1439419A (en) 1976-06-16
FR2215942A1 (en) 1974-08-30
NL7401361A (en) 1974-08-02
CA1035353A (en) 1978-07-25
PH14842A (en) 1981-12-16
FR2391728B1 (en) 1982-08-20
FR2391728A1 (en) 1978-12-22
JPS5953275B2 (en) 1984-12-24
JPS49101395A (en) 1974-09-25

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