SE404190B - Forfarande for framstellning av 7 (alfa-amino-p-hydroxifenylacetamido)-3-(1-metyl-5-tetrazolyltiometyl)-3-cefem-karboxylsyra och 7 (alfa-amino-p-hydroxifenylacetamido)-3-(5-metyl-1,3,4-tiadiazol-2-yltiometyl)-3-cefem... - Google Patents

Forfarande for framstellning av 7 (alfa-amino-p-hydroxifenylacetamido)-3-(1-metyl-5-tetrazolyltiometyl)-3-cefem-karboxylsyra och 7 (alfa-amino-p-hydroxifenylacetamido)-3-(5-metyl-1,3,4-tiadiazol-2-yltiometyl)-3-cefem...

Info

Publication number
SE404190B
SE404190B SE7304545A SE7304545A SE404190B SE 404190 B SE404190 B SE 404190B SE 7304545 A SE7304545 A SE 7304545A SE 7304545 A SE7304545 A SE 7304545A SE 404190 B SE404190 B SE 404190B
Authority
SE
Sweden
Prior art keywords
cefem
alfa
amino
yltiomethyl
tetrazolyltiomethyl
Prior art date
Application number
SE7304545A
Other languages
English (en)
Inventor
G L Dunn
J R E Hoover
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US262903A external-priority patent/US3867380A/en
Priority claimed from US00289499A external-priority patent/US3855213A/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of SE404190B publication Critical patent/SE404190B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7304545A 1972-06-14 1973-03-30 Forfarande for framstellning av 7 (alfa-amino-p-hydroxifenylacetamido)-3-(1-metyl-5-tetrazolyltiometyl)-3-cefem-karboxylsyra och 7 (alfa-amino-p-hydroxifenylacetamido)-3-(5-metyl-1,3,4-tiadiazol-2-yltiometyl)-3-cefem... SE404190B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US262903A US3867380A (en) 1971-02-18 1972-06-14 3-Heterocyclic thiomethylcephalosporins
US00289499A US3855213A (en) 1971-02-18 1972-09-15 3-heterocyclic thiomethyl-cephalosporins

Publications (1)

Publication Number Publication Date
SE404190B true SE404190B (sv) 1978-09-25

Family

ID=26949532

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7302579A SE416472B (sv) 1972-06-14 1973-02-23 Forfarande for framstellning av 7-(alfa-amino-p-hydroxifenylacetamido)-3-(1,2,3-triazolyltiometyl)-3-cefem-4-karboxylsyror
SE7304545A SE404190B (sv) 1972-06-14 1973-03-30 Forfarande for framstellning av 7 (alfa-amino-p-hydroxifenylacetamido)-3-(1-metyl-5-tetrazolyltiometyl)-3-cefem-karboxylsyra och 7 (alfa-amino-p-hydroxifenylacetamido)-3-(5-metyl-1,3,4-tiadiazol-2-yltiometyl)-3-cefem...

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7302579A SE416472B (sv) 1972-06-14 1973-02-23 Forfarande for framstellning av 7-(alfa-amino-p-hydroxifenylacetamido)-3-(1,2,3-triazolyltiometyl)-3-cefem-4-karboxylsyror

Country Status (20)

Country Link
JP (2) JPS5518716B2 (sv)
AR (1) AR197237A1 (sv)
AT (1) AT324560B (sv)
AU (1) AU464107B2 (sv)
CA (2) CA1076560A (sv)
CH (2) CH586709A5 (sv)
DD (1) DD105238A5 (sv)
DE (1) DE2316867C2 (sv)
DK (1) DK142913B (sv)
ES (2) ES412207A1 (sv)
FI (1) FI56843C (sv)
FR (2) FR2187298B1 (sv)
GB (2) GB1363833A (sv)
HU (1) HU168689B (sv)
IE (2) IE37409B1 (sv)
IL (1) IL42126A (sv)
NL (2) NL7302817A (sv)
PH (1) PH9941A (sv)
PL (1) PL91074B1 (sv)
SE (2) SE416472B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR780000197B1 (en) * 1972-12-26 1978-05-26 Bristol Myers Co Method for preparing antibacterial agent
PH16419A (en) * 1973-01-31 1983-09-29 Bristol Myers Co 7-(d-alpha-amino-alpha-(3'-methyl-4'-hydroxyphenyl)-acetamido)-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid,pharmaceutically acceptable esters and salts thereof
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
CA1074784A (en) * 1974-09-06 1980-04-01 Sumitomo Chemical Company N-ACYLAMINO-.alpha.-ARYLACETAMIDO CEPHALOSPORINS
JPS5346995A (en) * 1976-10-12 1978-04-27 Sangyo Kagaku Kenkyu Kyokai Antibacterial agents
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
JPS6182606A (ja) * 1984-09-29 1986-04-26 東芝ライテック株式会社 昇降装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA698494B (en) * 1969-02-26 1971-07-28 Lilly Co Eli Sulfur-containing cephalosporing antibiotics
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
IE37409B1 (en) 1977-07-20
IE37499B1 (en) 1977-08-03
DD105238A5 (sv) 1974-04-12
FI56843C (fi) 1980-04-10
GB1363833A (en) 1974-08-21
ES412207A1 (es) 1976-01-01
DE2316866B2 (de) 1976-10-07
ES413501A1 (es) 1976-07-16
CA999293A (en) 1976-11-02
NL7302817A (sv) 1973-12-18
JPS4931689A (sv) 1974-03-22
CH586709A5 (sv) 1977-04-15
JPS5953274B2 (ja) 1984-12-24
AR197237A1 (es) 1974-03-22
JPS4954393A (sv) 1974-05-27
FR2187298B1 (sv) 1976-12-03
IE37499L (en) 1973-12-14
IL42126A0 (en) 1973-06-29
JPS5518716B2 (sv) 1980-05-21
SE416472B (sv) 1981-01-05
DK142913B (da) 1981-02-23
FI56843B (fi) 1979-12-31
AU464107B2 (en) 1975-08-14
CH589093A5 (sv) 1977-06-30
HU168689B (sv) 1976-06-28
FR2187298A1 (sv) 1974-01-18
IL42126A (en) 1975-12-31
AT324560B (de) 1975-09-10
FR2187299A1 (sv) 1974-01-18
FR2187299B1 (sv) 1976-12-03
DE2316867C2 (de) 1982-05-19
NL7305206A (sv) 1973-12-18
DE2316867A1 (de) 1974-01-03
PL91074B1 (en) 1977-02-28
CA1076560A (en) 1980-04-29
PH9941A (en) 1976-06-14
GB1358027A (en) 1974-06-26
DE2316866A1 (de) 1974-01-03
AU5234573A (en) 1974-08-22
IE37409L (en) 1973-12-14
DK142913C (sv) 1981-09-28

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